Up-regulation of heat shock protein 70-1 (Hsp70-1) in human limbo-corneal epithelial cells cultivated on amniotic membrane: A proteomic studyDavid Hui Kang Ma
Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
J Cell Physiol 227:2030-9. 2012
..Thus, deltaNp63α-associated Hsp70-1 over-expression may promote HLE progenitor cell survival on IAM, possibly through the cytoprotective and anti-apoptotic effect of Hsp70-1...
Regulation of corneal angiogenesis in limbal stem cell deficiencyDavid Hui Kang Ma
Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC
Prog Retin Eye Res 25:563-90. 2006
..These findings highlight the significance of delicate epithelial-matrix interactions in the maintenance of corneal avascularity...
- Comparison of amniotic membrane graft alone or combined with intraoperative mitomycin C to prevent recurrence after excision of recurrent pterygia
David Hui Kang Ma
Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Cornea 24:141-50. 2005
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- Generation of endostatin by matrix metalloproteinase and cathepsin from human limbocorneal epithelial cells cultivated on amniotic membrane
David Hui Kang Ma
Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Kweishan Township, Taoyuan County 333, Taiwan
Invest Ophthalmol Vis Sci 48:644-51. 2007
..This study is to identify mechanisms for enhanced endostatin production by HLE cells cultivated on AM...
- Transplantation of cultivated oral mucosal epithelial cells for severe corneal burn
D H K Ma
Department of Ophthalmology, Chang Gung Memorial Hospital, Department of Chinese Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan
Eye (Lond) 23:1442-50. 2009
..To access the feasibility of using cultivated oral mucosal epithelial cell transplantation (COMET) for the management of severe corneal burn...
- Long-term observation of aqueous flare following penetrating keratoplasty
David Hui Kang Ma
Department of Ophtalmology, Chang Gung Memorial Hospital, Kwei Shan Township, Taoyuan County, Taiwan
Cornea 22:413-9. 2003
..To understand the influence of preoperative corneal conditions, combined implant surgeries, and subsequent rejection on the aqueous flare value following penetrating keratoplasty (PK)...
- Expression of tissue inhibitor of metalloproteinase-4 in normal human corneal cells and experimental corneal neovascularization
David Hui Kang Ma
Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Ophthalmic Res 35:199-207. 2003
..To study the expression of TIMP-4 in cultured corneal cells and in corneal neovascularization...
- Matrix revolution: molecular mechanism for inflammatory corneal neovascularization and restoration of corneal avascularity by epithelial stem cell transplantation
David Hui Kang Ma
Limbal Stem Cell Laboratory, Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Ocul Surf 7:128-44. 2009
..Taken together, the merits of enhanced anti-angiogenic activity and the preservation of corneal epithelial stem cells encourage further application of this tissue engineering technique for ocular surface reconstruction...
- In vitro antiangiogenic activity in ex vivo expanded human limbocorneal epithelial cells cultivated on human amniotic membrane
David Hui-Kang Ma
Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Invest Ophthalmol Vis Sci 45:2586-95. 2004
..This highlights the significance of cell-matrix and cell-cell interaction in the regulation of antiangiogenic factor secretion by HLE cells...
- Amniotic membrane transplantation for persistent corneal ulcers and perforations in acute fungal keratitis
Hung-Chi Chen
Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Cornea 25:564-72. 2006
..However, the risk of persistent or recurrent infection necessitates continued antifungal treatment and patient monitoring...
- Amniotic membrane graft for the management of scleral melting and corneal perforation in recalcitrant infectious scleral and corneoscleral ulcers
David Hui-Kang Ma
Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
Cornea 21:275-83. 2002
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- Inhibition of fibroblast-induced angiogenic phenotype of cultured endothelial cells by the overexpression of tissue inhibitor of metalloproteinase (TIMP)-3
David Hui-Kang Ma
Department of Ophthalmology, Chang-Gung Memorial Hospital, Chang-Gung University, Kweishan, Taoyuan, Taiwan
J Biomed Sci 10:526-34. 2003
..Overexpression of TIMP-3 by ECs may be considered a gene therapy strategy for the treatment of pathological angiogenesis such as cancer and diabetic retinopathy...
- Amniotic membrane transplantation for pseudomonal keratitis with impending perforation
Jesse Hung-Chi Chen
Department of Ophthalmology, Chang Gung Memorial Hospital, Taipei
Chang Gung Med J 25:144-52. 2002
..CONCLUSION: AMT may be considered an alternative method for treating pseudomonal keratitis, especially when stromal melting and loss are extensive, and the infection has been controlled...
- Amniotic membrane grafts following excision of corneal and conjunctival intraepithelial neoplasia
Lung Kun Yeh
Department of Ophthalmology, Chang Gung Memorial Hospital, Taipei
Chang Gung Med J 26:737-44. 2003
..CONCLUSION: Amniotic membrane graft is an effective and safe alternative adjunctive treatment for primary CIN. Further studies with longer follow-up are recommended to evaluate the risk of recurrence and other adverse effects...
- Late onset lamellar keratitis and epithelial ingrowth following orbital cellulitis
Ching-Liang Kuo
Department of Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China
J Refract Surg 22:202-4. 2006
..CONCLUSIONS: Lamellar keratitis does not always occur early following LASIK and may be associated with orbital cellulitis...
- Carbodiimide cross-linked hyaluronic acid hydrogels as cell sheet delivery vehicles: characterization and interaction with corneal endothelial cells
Pei Lin Lu
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan 30013, Republic of China
J Biomater Sci Polym Ed 19:1-18. 2008
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