In Kyoon Lyoo

Summary

Publications

  1. doi request reprint The neurobiological role of the dorsolateral prefrontal cortex in recovery from trauma. Longitudinal brain imaging study among survivors of the South Korean subway disaster
    In Kyoon Lyoo
    Department of Psychiatry and Interdisciplinary Program in Neuroscience, Seoul National University College of Medicine and College of Natural Sciences, 28 Yongon Dong, Jongno gu, 110 744 Seoul, South Korea
    Arch Gen Psychiatry 68:701-13. 2011
  2. pmc Morphometric changes in lateral ventricles of patients with recent-onset type 2 diabetes mellitus
    Junghyun H Lee
    Department of Pharmacy, Ewha University College of Pharmacy, Seoul, South Korea
    PLoS ONE 8:e60515. 2013
  3. pmc Neurochemical alterations in methamphetamine-dependent patients treated with cytidine-5'-diphosphate choline: a longitudinal proton magnetic resonance spectroscopy study
    Sujung J Yoon
    Department of Psychiatry, Catholic University of Korea School of Medicine, Seoul, South Korea
    Neuropsychopharmacology 35:1165-73. 2010
  4. pmc Network-level structural abnormalities of cerebral cortex in type 1 diabetes mellitus
    In Kyoon Lyoo
    Ewha Brain Institute and College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha W University, Seoul, South Korea
    PLoS ONE 8:e71304. 2013
  5. doi request reprint Laterobasal amygdalar enlargement in 6- to 7-year-old children with autism spectrum disorder
    Jieun E Kim
    Department of Psychiatry, Seoul National University, Seoul, South Korea
    Arch Gen Psychiatry 67:1187-97. 2010
  6. doi request reprint Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study
    Sujung J Yoon
    Department of Psychiatry, Catholic University College of Medicine, Seoul, South Korea
    Neuropsychopharmacology 34:1810-8. 2009
  7. pmc Lithium-induced gray matter volume increase as a neural correlate of treatment response in bipolar disorder: a longitudinal brain imaging study
    In Kyoon Lyoo
    Department of Psychiatry, Seoul National University, Seoul, South Korea
    Neuropsychopharmacology 35:1743-50. 2010
  8. doi request reprint Altered cortical gyrification patterns in panic disorder: deficits and potential compensation
    Sujung Yoon
    Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, South Korea
    J Psychiatr Res 47:1446-54. 2013
  9. pmc Clinical response of quetiapine in rapid cycling manic bipolar patients and lactate level changes in proton magnetic resonance spectroscopy
    Dajung J Kim
    Department of Psychiatry, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul, 110 744, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:1182-8. 2007
  10. doi request reprint Associations between anterior cingulate cortex glutamate and gamma-aminobutyric acid concentrations and the harm avoidance temperament
    Hengjun J Kim
    Interdisciplinary Program in Brain Science, Seoul National University College of Natural Sciences, Seoul, South Korea
    Neurosci Lett 464:103-7. 2009

Collaborators

  • Perry F Renshaw
  • Sujung J Yoon
  • Christopher M Ryan
  • Jeanyung Chey
  • Deborah A Yurgelun-Todd
  • David L Dunner
  • Min Soo Lee
  • Jee Hyun Ha
  • Young Mee Lee
  • Jun Young Lee
  • Namhee Choi
  • Su Yeon Kim
  • Bruce M Cohen
  • Boong Nyun Kim
  • Min Sup Shin
  • Eun Young Kim
  • Jaeuk Hwang
  • Jieun E Kim
  • Byung Joo Ham
  • Doug Hyun Han
  • Byeong Taek Lee
  • Dajung J Kim
  • Han Byul Cho
  • Stephen R Dager
  • Hengjun J Kim
  • Namkug Kim
  • Ihn Geun Choi
  • Ain Chung
  • Young Hoon Sung
  • Sunho Lee
  • Hyeonseok S Jeong
  • Dajung Kim
  • Minue J Kim
  • Seth D Friedman
  • Do Un Jeong
  • Younghoon Sung
  • In Chan Song
  • Soojeong Bae
  • Jun Won Hwang
  • Soojeong C Bae
  • Jungsu S Oh
  • Chansoo Jun
  • Marc J Kaufman
  • Soonhyun Ban
  • Sun Hea Lee
  • Eun Ko
  • Yera Choi
  • Jiyoung Ma
  • Jiyoung J Jung
  • Jooyeon Jamie Im
  • Dennis W Shaw
  • Annette M Estes
  • Jeong Ho Chae
  • Jong Woo Kim
  • Gyunggoo Cho
  • Tae Suk Kim
  • Jong Woo Paik
  • Sujin Bae
  • Seokjun J Hong
  • Rhee Hun Kang
  • Hyun Soo Khang
  • Sun Yong Chung
  • Jung Hye Kwon
  • Ho In Kwon
  • Byungjoo Ham
  • Hyunsoo Khang
  • Kevin C Yang
  • Jihyun H Kim
  • Minyoung E Sim
  • Seog Ju Kim
  • - Seong Whi Cho
  • Taeyoung Choi
  • Byungchol Lee
  • - Hyung Soo Khang
  • Boung Chul Lee
  • Ho Young Lee
  • Soo Churl Cho
  • Jaeun Yoo
  • Dai Jin Kim
  • Meyoung Kon Kim
  • Dong Soo Lee
  • Sung Nam Cho
  • Jung Su Oh
  • Myoung Jin Choi
  • Duck Sun Ahn
  • Jihyun Kim
  • Kwang Suk Park

Detail Information

Publications31

  1. doi request reprint The neurobiological role of the dorsolateral prefrontal cortex in recovery from trauma. Longitudinal brain imaging study among survivors of the South Korean subway disaster
    In Kyoon Lyoo
    Department of Psychiatry and Interdisciplinary Program in Neuroscience, Seoul National University College of Medicine and College of Natural Sciences, 28 Yongon Dong, Jongno gu, 110 744 Seoul, South Korea
    Arch Gen Psychiatry 68:701-13. 2011
    ....
  2. pmc Morphometric changes in lateral ventricles of patients with recent-onset type 2 diabetes mellitus
    Junghyun H Lee
    Department of Pharmacy, Ewha University College of Pharmacy, Seoul, South Korea
    PLoS ONE 8:e60515. 2013
    ..The current findings suggest that atrophic changes particularly of the anterior frontal lobe can occur as early as the first year after the clinical diagnosis of type 2 diabetes mellitus...
  3. pmc Neurochemical alterations in methamphetamine-dependent patients treated with cytidine-5'-diphosphate choline: a longitudinal proton magnetic resonance spectroscopy study
    Sujung J Yoon
    Department of Psychiatry, Catholic University of Korea School of Medicine, Seoul, South Korea
    Neuropsychopharmacology 35:1165-73. 2010
    ..Further studies with a larger sample size of MA-dependent patients are warranted to confirm a long-term efficacy of CDP-choline in neuroprotection and abstinence...
  4. pmc Network-level structural abnormalities of cerebral cortex in type 1 diabetes mellitus
    In Kyoon Lyoo
    Ewha Brain Institute and College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha W University, Seoul, South Korea
    PLoS ONE 8:e71304. 2013
    ..The current results provide structural evidence for T1DM-related dysfunctional cortical organization, which specifically underlie the top-down cognitive control of language, memory, and emotion. ..
  5. doi request reprint Laterobasal amygdalar enlargement in 6- to 7-year-old children with autism spectrum disorder
    Jieun E Kim
    Department of Psychiatry, Seoul National University, Seoul, South Korea
    Arch Gen Psychiatry 67:1187-97. 2010
    ..To date, we are not aware of any in vivo reports specifically assessing subregional amygdalar abnormalities in individuals with ASD...
  6. doi request reprint Decreased glutamate/glutamine levels may mediate cytidine's efficacy in treating bipolar depression: a longitudinal proton magnetic resonance spectroscopy study
    Sujung J Yoon
    Department of Psychiatry, Catholic University College of Medicine, Seoul, South Korea
    Neuropsychopharmacology 34:1810-8. 2009
    ..Furthermore, cytidine's efficacy in bipolar depression may be mediated by decreased levels of cerebral glutamate and/or glutamine, consistent with alterations in excitatory neurotransmission...
  7. pmc Lithium-induced gray matter volume increase as a neural correlate of treatment response in bipolar disorder: a longitudinal brain imaging study
    In Kyoon Lyoo
    Department of Psychiatry, Seoul National University, Seoul, South Korea
    Neuropsychopharmacology 35:1743-50. 2010
    ..Results suggest that lithium induces sustained increases in cerebral gray matter volume in patients with BD and that these changes are related to the therapeutic efficacy of lithium...
  8. doi request reprint Altered cortical gyrification patterns in panic disorder: deficits and potential compensation
    Sujung Yoon
    Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, South Korea
    J Psychiatr Res 47:1446-54. 2013
    ..Our findings suggest not only substantial perturbation in cortical gyrification patterns in panic disorder but also potential contribution of integrated cortical folding pattern of the default mode network to alleviated panic severity. ..
  9. pmc Clinical response of quetiapine in rapid cycling manic bipolar patients and lactate level changes in proton magnetic resonance spectroscopy
    Dajung J Kim
    Department of Psychiatry, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul, 110 744, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:1182-8. 2007
    ..52, p=0.003). Our findings suggest that quetiapine's antimanic and antidepressant efficacy in patients with rapid cycling bipolar disorder may potentially be related to decreased lactate levels in frontal regions of the brain...
  10. doi request reprint Associations between anterior cingulate cortex glutamate and gamma-aminobutyric acid concentrations and the harm avoidance temperament
    Hengjun J Kim
    Interdisciplinary Program in Brain Science, Seoul National University College of Natural Sciences, Seoul, South Korea
    Neurosci Lett 464:103-7. 2009
    ..48, df=30, P=0.005). These findings suggest that glutamate and GABA concentrations in ACC are closely related to levels of the HA temperament in healthy subjects...
  11. ncbi request reprint The neural substrates of affective processing toward positive and negative affective pictures in patients with major depressive disorder
    Byeong Taek Lee
    Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:1487-92. 2007
    ..Also, these findings suggest that the bilateral inferior orbitofrontal cortices and left amygdala may be preferentially recruited in MDD patients, but not in healthy individuals...
  12. ncbi request reprint Altered prefrontal glutamate-glutamine-gamma-aminobutyric acid levels and relation to low cognitive performance and depressive symptoms in type 1 diabetes mellitus
    In Kyoon Lyoo
    Department of Psychiatry and Interdisciplinary Program in Brain Science, Seoul National University, 28 Yongon Dong, Jongno gu, Seoul 110 744, South Korea
    Arch Gen Psychiatry 66:878-87. 2009
    ..Neural substrates for low cognitive performance and depression, common long-term central nervous system-related changes in patients with type 1 diabetes mellitus, have not yet been studied...
  13. ncbi request reprint Decreased N-acetyl-aspartate levels in anterior cingulate and hippocampus in subjects with post-traumatic stress disorder: a proton magnetic resonance spectroscopy study
    Byung Joo Ham
    Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    Eur J Neurosci 25:324-9. 2007
    ....
  14. ncbi request reprint Decreased GABA levels in anterior cingulate and basal ganglia in medicated subjects with panic disorder: a proton magnetic resonance spectroscopy (1H-MRS) study
    Byung Joo Ham
    Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:403-11. 2007
    ..Our data suggested in part that alterations of the GABA function and the energy metabolism in ACC and basal ganglia may play an important role in the pathophysiology of panic disorder...
  15. ncbi request reprint Diminished rostral anterior cingulate activity in response to threat-related events in posttraumatic stress disorder
    Minue J Kim
    Department of Psychology, Seoul National University, Seoul, South Korea
    J Psychiatr Res 42:268-77. 2008
    ..The current study specifically focuses on the abnormal activity of the rostral anterior cingulate, using a paradigm which elicits an unexpected processing conflict caused by salient emotional stimuli...
  16. doi request reprint Amygdalar shape analysis method using surface contour aligning, spherical mapping, and probabilistic subregional segmentation
    Namkug Kim
    Department of Radiology, Ulsan University College of Medicine, Seoul, South Korea
    Neurosci Lett 488:65-9. 2011
    ..This is generally in agreement with previous findings from animal studies. The current method may be used for measuring subtle local shape changes of the amygdala in various psychiatric or neurologic disorders...
  17. ncbi request reprint A randomized, double-blind placebo-controlled trial of oral creatine monohydrate augmentation for enhanced response to a selective serotonin reuptake inhibitor in women with major depressive disorder
    In Kyoon Lyoo
    Department of Psychiatry and the Interdisciplinary Program in Neuroscience, Seoul National University College of Medicine, Seoul, South Korea
    Am J Psychiatry 169:937-45. 2012
    ..Such augmentation may lead to a more rapid onset of antidepressant effects and a greater treatment response, potentially by restoring brain bioenergetics at the cellular level...
  18. ncbi request reprint Posterior cerebellar vermal deficits in bipolar disorder
    Dajung Kim
    Interdisciplinary Program in Neuroscience, Seoul National University, Seoul, South Korea
    J Affect Disord 150:499-506. 2013
    ..Based on growing evidence of the crucial role of the cerebellum in emotional regulation, we sought to identify cerebellar structural deficits in a large sample of patients with bipolar disorder (BD)...
  19. doi request reprint Morphometric abnormalities of the lateral ventricles in methamphetamine-dependent subjects
    Hyeonseok S Jeong
    Interdisciplinary Program in Neuroscience, Seoul National University College of Natural Sciences, 103 Daehak Ro, Jongno gu, Seoul 110 799, South Korea
    Drug Alcohol Depend 131:222-9. 2013
    ..The current study was aimed to examine the size and shape alterations of the lateral ventricles in methamphetamine-dependent subjects...
  20. pmc Enlarged cavum septum pellucidum as a neurodevelopmental marker in adolescent-onset opiate dependence
    Jaeuk Hwang
    Department of Psychiatry, Soonchunhyang University College of Medicine, Seoul, South Korea
    PLoS ONE 8:e78590. 2013
    ..Here we examined whether having an abnormally large cavum septum pellucidum (CSP), a putative marker of limbic structural maldevelopment, is associated with opiate dependence particularly beginning in adolescence...
  21. ncbi request reprint Increased white matter hyperintensities in male methamphetamine abusers
    Soojeong C Bae
    Department of Psychiatry, Seoul National University College of Medicine and Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Drug Alcohol Depend 81:83-8. 2006
    ..The current study was conducted to compare the prevalence, severity, and location of white matter signal hyperintensities (WMH) on brain magnetic resonance (MR) imaging in methamphetamine (MA) abusers...
  22. ncbi request reprint Decreased cerebral blood flow of the right anterior cingulate cortex in long-term and short-term abstinent methamphetamine users
    Jaeuk Hwang
    Department of Psychiatry, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Drug Alcohol Depend 82:177-81. 2006
    ..The aim of the current study was to explore changes of relative regional cerebral blood flow (rCBF) in short-term and long-term abstinent methamphetamine (MA) users...
  23. ncbi request reprint Advances in magnetic resonance imaging methods for the evaluation of bipolar disorder
    In Kyoon Lyoo
    Department of Psychiatry, Seoul National University, South Korea, Seoul, South Korea
    CNS Spectr 11:269-80. 2006
    ..Integrative issues and future directions in this relatively young field, including multi-modal approaches enabling us to produce more comprehensive results, are discussed...
  24. doi request reprint Differential regional gray matter volumes in patients with on-line game addiction and professional gamers
    Doug Hyun Han
    Department of Psychiatry, Chung Ang University, College of Medicine, Seoul, South Korea
    J Psychiatr Res 46:507-15. 2012
    ..The current study suggests that increased gray matter volumes of the left cingulate gyrus in pro-gamers and of the left thalamus in POGA may contribute to the different clinical characteristics of pro-gamers and POGA...
  25. ncbi request reprint Depression and Internet addiction in adolescents
    Jee Hyun Ha
    Department of Psychiatry, School of Medicine, Konkuk University, Seoul, South Korea
    Psychopathology 40:424-30. 2007
    ..Third, the relationship between Internet addiction and biogenetic temperament as assessed by the Temperament and Character Inventory was evaluated...
  26. doi request reprint The neural substrates of affective face recognition in patients with Hwa-Byung and healthy individuals in Korea
    Byeong Taek Lee
    Department of Psychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    World J Biol Psychiatry 10:552-9. 2009
    ..The current study indicates that the suppression of affect results in aberrant function of the brain regions of the visual pathway, and functional impairment in the ACC may contribute to the pathophysiology of HB...
  27. ncbi request reprint The relationship between temperament and character and psychopathology in community children with overweight
    Jun Won Hwang
    Department of Psychiatry, Seoul National University College of Medicine, Seoul, South Korea
    J Dev Behav Pediatr 27:18-24. 2006
    ..Compared to nonoverweight and children at risk of overweight, overweight children had distinct patterns of temperament and character that were related to the specific psychopathology...
  28. ncbi request reprint Basal ganglia shape alterations in bipolar disorder
    Jaeuk Hwang
    Department of Psychiatry, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul 110 744, South Korea
    Am J Psychiatry 163:276-85. 2006
    ....
  29. ncbi request reprint Personality, dopamine receptor D4 exon III polymorphisms, and academic achievement in medical students
    Byung Joo Ham
    Department of Neuropsychiatry, Hangang Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea
    Neuropsychobiology 53:203-9. 2006
    ....
  30. ncbi request reprint Dopamine genes and reward dependence in adolescents with excessive internet video game play
    Doug Hyun Han
    From McLean Hospital Brain Imaging Center and Department of Psychiatry DHH, KCY, IKL, PFR, Harvard Medical School, Belmont, MA the Department of Psychiatry YSL, EYK, Chung Ang University Medical School, Seoul, South Korea and the Department of Psychiatry IKL, Seoul National University College of Medicine, Seoul, South Korea
    J Addict Med 1:133-8. 2007
    ..In particular, the DRD2 Taq1A1 allele seems to be associated with reward dependence in EIGP adolescents...
  31. ncbi request reprint Shape changes of the corpus callosum in abstinent methamphetamine users
    Jungsu S Oh
    Interdisciplinary Program in Medical and Biological Engineering, Seoul National University, 28 Yongun Dong Chongno Gu, Seoul, South Korea
    Neurosci Lett 384:76-81. 2005
    ....