Research Topics
| Robert WennigSummaryAffiliation: University of Luxembourg Country: Luxembourg Publications
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Detail Information
Publications
Back to the roots of modern analytical toxicology: Jean Servais Stas and the Bocarmé murder caseRobert Wennig
Laboratoire National de Santé Toxicologie, Université du Luxembourg, Luxembourg
Drug Test Anal 1:153-5. 2009..During court trial this identification was challenged by his mentor M. J. B. Orfila from Paris, who had stated 3 years before, that it would never be possible to isolate and identify organic poisons from organ tissues...
GC/MS based identification of skunk spray maliciously deployed as "biological weapon" to harm civiliansRobert Wennig
Laboratoire National de Santé, Toxicologie, Université du Luxembourg, 162A Avenue de la Faïencerie, L 1511 Luxembourg, Luxembourg
J Chromatogr B Analyt Technol Biomed Life Sci 878:1433-6. 2010..No health sequels were observed for any of the persons implicated in this case...
Ethyl glucuronide determination: head hair versus non-head hairIsabelle Kerekes
Laboratoire National de Santé Toxicologie, Université du Luxembourg, Luxembourg
Alcohol Alcohol 44:62-6. 2009..As in some cases scalp hair is not available, the analysis of hair from alternative anatomical sites becomes of interest...
Determination of fentanyl in sweat and hair of a patient using transdermal patchesSerge Schneider
Laboratoire National de Santé, Division de Toxicologie, Université du Luxembourg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
J Anal Toxicol 32:260-4. 2008..Fentanyl concentrations in sweat varied from 0.17 to 1.02 ng/microL, and time-resolved segmented hair analysis showed a maximum fentanyl concentration of 0.48 ng/mg of hair during the period of the therapy...
Influence of bleaching on the enantiomeric disposition of amphetamine-type stimulants in hairLiliane Ferreira Martins
National Laboratory of Health, Toxicology Division, University of Luxembourg, 162A Avenue de la Faïencerie, L 1511, Luxembourg
Forensic Sci Int 176:38-41. 2008..Our findings pointed out that bleaching treatments decrease concentrations of STA in hair without influencing their enantiomeric ratios...
Ethyl glucuronide concentration in hair is not influenced by pigmentationBrice M R Appenzeller
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
Alcohol Alcohol 42:326-7. 2007..The results confirm that, unlike many other substances, the EtG determination in hair has not to take into account the hair colour for the correct interpretation of hair testing results...
Segmental determination of ethyl glucuronide in hair: a pilot studyBrice M R Appenzeller
Centre de Recherche Public Santé Laboratoire National de Santé, Laboratoire de Toxicologie, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
Forensic Sci Int 173:87-92. 2007..Variations in the EtG concentrations with respect to hair segments may provide an overview of the drinking history of patients. Moreover, EtG concentration in hair may help to estimate the daily alcohol intake...
Time-resolved hair analysis of MDMA enantiomers by GC/MS-NCILiliane Ferreira Martins
National Laboratory of Health, Toxicology Division, University of Luxembourg, Luxembourg, Luxembourg
Forensic Sci Int 172:150-5. 2007..Furthermore, both enantiomers of amphetamine (AM) were also detected in hair segments of four volunteers and the R/S ratios ranged from 1.00 to 1.47...
Was a child poisoned by ethanol? Discrimination between ante-mortem consumption and post-mortem formationBrice M R Appenzeller
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, 1511, Luxembourg, Luxembourg
Int J Legal Med 122:429-34. 2008..The absence of EtG in the liver of the deceased compared to the high level (19.56 mug/g) detected in the positive control's liver is a further indication that the ethanol detected in the body of the deceased is of post-mortem origin...
Time resolved analysis of risperidone and 9-hydroxy-risperidone in hair using LC/MS-MSSerge Schneider
Laboratoire National de Santé, Division de Toxicologie, Université du Luxembourg, 162A, avenue de la Faiencerie, L 1511 Luxembourg, Luxembourg
J Chromatogr B Analyt Technol Biomed Life Sci 877:2589-92. 2009..These preliminary results indicate a better relationship between the administered dose and hair concentration for 9-OH-RSP than for the parent drug. Furthermore, the RSP/9-OH-RSP ratio varied from 1 to 83...
Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in human hair by gas chromatography-negative chemical ionization mass spectrometryClaude Schummer
Laboratoire de Toxicologie, CRP Sante, Université du Luxembourg, Campus Limpertsberg, 1511 Luxembourg, Luxembourg
J Chromatogr A 1216:6012-9. 2009..According to the easiness of hair sampling and based on the extended detection windows provided by hair analysis, this method is proposed as a new promising tool for the assessment of human chronic exposure to PAHs...
Internet suicide guidelines: report of a life-threatening poisoning using tobacco extractSerge Schneider
Laboratoire National de Santé, Division de Toxicologie, Université du Luxembourg, Luxembourg
J Emerg Med 38:610-3. 2010..Severe nicotine intoxication occurred in a patient after ingestion of a tobacco extract made from a recipe found on a freely available Internet site...
Simultaneous enantioselective quantification of methadone and of 2-ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine in oral fluid using capillary electrophoresisLiliane F Martins
National Laboratory of Health, Toxicology Division, University of Luxembourg, 162A, avenue de la Faiencerie, L 1511 Luxembourg, Luxembourg
J Chromatogr B Analyt Technol Biomed Life Sci 862:79-85. 2008..Our data pointed out that higher concentrations of (R)-MTD and the enantioselective excess of (S)-EDDP in OF may reflect the free fraction of MTD and EDDP enantiomers in plasma...
Sensitive, rapid and validated gas chromatography/negative ion chemical ionization-mass spectrometry assay including derivatisation with a novel chiral agent for the enantioselective quantification of amphetamine-type stimulants in hairLiliane Ferreira Martins
National Laboratory of Health, Toxicology Division, University of Luxembourg, 162A Avenue de la Faïencerie, L 1511 Luxembourg, Luxembourg
J Chromatogr B Analyt Technol Biomed Life Sci 842:98-105. 2006..One hair specimen was tested positive for both enantiomers of MDMA and MDA...
Quantification of lorazepam and lormetazepam in human breast milk using GC-MS in the negative chemical ionization modePatrick Lemmer
Laboratoire National de Santé, Division de Toxicologie, Université de Luxembourg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
J Anal Toxicol 31:224-6. 2007..100 ng/mL for lorazepam. Our method was applied to real case samples from a woman receiving both benzodiazepines. Lorazepam concentrations varied from 55.3 to 123.1 ng/mL, and lormetazepam concentrations varied from 1.7 to 7.3 ng/mL...
Efavirenz in human breast milk, mothers', and newborns' plasmaSerge Schneider
Laboratoire National de la Santé, Division de Toxicologie, Université du Luxembourg, Luxembourg, Luxembourg
J Acquir Immune Defic Syndr 48:450-4. 2008..The EFV concentrations in maternal plasma, breast milk and in newborns' plasma of 13 women and their children between 6 weeks and 6 months post partum are reported...
Drugs and chronic alcohol abuse in driversBrice M R Appenzeller
Centre de Recherche Public, Santé Laboratoire National de Santé, Division de Toxicologie, Université du Luxembourg, Campus Limpertsberg, 162A Avenue de la Faïencerie, L 1511 Luxembourg, Luxembourg
Forensic Sci Int 155:83-90. 2005..Medicinal psychoactive drugs were clearly associated with poly-drug use, and were furthermore detected at supra-therapeutic levels in 34.9%...
Determination of the volume of sweat accumulated in a sweat-patch using sodium and potassium as internal referenceBrice M R Appenzeller
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé Université du Luxembourg, Campus Limpertsberg, 162A Avenue de la Faïencerie, L 1511 Luxembourg
J Chromatogr B Analyt Technol Biomed Life Sci 852:333-7. 2007..0%. Results demonstrated the usefulness of sodium as internal standard to determine the volume of sweat accumulated in a patch, and confirm the suitability of PharmChek patch for the collection and determination of cations in sweat...
