Research Topics
| Brice M R AppenzellerSummaryAffiliation: Laboratoire National de Sant Country: Luxembourg Publications
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Detail Information
Publications
Was a child poisoned by ethanol? Discrimination between ante-mortem consumption and post-mortem formationBrice M R Appenzeller
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, 1511, Luxembourg, Luxembourg
Int J Legal Med 122:429-34. 2008..The absence of EtG in the liver of the deceased compared to the high level (19.56 mug/g) detected in the positive control's liver is a further indication that the ethanol detected in the body of the deceased is of post-mortem origin...
Ethyl glucuronide concentration in hair is not influenced by pigmentationBrice M R Appenzeller
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
Alcohol Alcohol 42:326-7. 2007..The results confirm that, unlike many other substances, the EtG determination in hair has not to take into account the hair colour for the correct interpretation of hair testing results...
Determination of the volume of sweat accumulated in a sweat-patch using sodium and potassium as internal referenceBrice M R Appenzeller
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé Université du Luxembourg, Campus Limpertsberg, 162A Avenue de la Faïencerie, L 1511 Luxembourg
J Chromatogr B Analyt Technol Biomed Life Sci 852:333-7. 2007..0%. Results demonstrated the usefulness of sodium as internal standard to determine the volume of sweat accumulated in a patch, and confirm the suitability of PharmChek patch for the collection and determination of cations in sweat...
Drugs and chronic alcohol abuse in driversBrice M R Appenzeller
Centre de Recherche Public, Santé Laboratoire National de Santé, Division de Toxicologie, Université du Luxembourg, Campus Limpertsberg, 162A Avenue de la Faïencerie, L 1511 Luxembourg, Luxembourg
Forensic Sci Int 155:83-90. 2005..Medicinal psychoactive drugs were clearly associated with poly-drug use, and were furthermore detected at supra-therapeutic levels in 34.9%...
Quantitative determination of ethyl glucuronide in sweatClaude Schummer
Laboratoire de Toxicologie, Centre de Recherche Public Santé Laboratoire National de Santé, Luxembourg
Ther Drug Monit 30:536-9. 2008..This study suggests that EtG determination in sweat could represent an interesting alternative to urine or serum analysis for the control of abstinence of patients included in treatment programs...
Determination of farm workers' exposure to pesticides by hair analysisClaude Schummer
Laboratory of Analytical Human Biomonitoring CRP Santé, Université du Luxembourg, 162A Avenue de la Faïencerie, L 1511, Luxembourg
Toxicol Lett 210:203-10. 2012..Observations also suggest that spraying work would not necessarily be the only source of exposure to agricultural pesticides and that worker not directly involved in spraying can also be submitted to significant level of exposure...
Segmental determination of ethyl glucuronide in hair: a pilot studyBrice M R Appenzeller
Centre de Recherche Public Santé Laboratoire National de Santé, Laboratoire de Toxicologie, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
Forensic Sci Int 173:87-92. 2007..Variations in the EtG concentrations with respect to hair segments may provide an overview of the drinking history of patients. Moreover, EtG concentration in hair may help to estimate the daily alcohol intake...
Simultaneous determination of nicotine and PAH metabolites in human hair specimen: a potential methodology to assess tobacco smoke contribution in PAH exposureBrice M R Appenzeller
Laboratory of Analytical Human Biomonitoring CRP Santé, Université du Luxembourg, 162A Avenue de la Faïencerie, L 1511, Luxembourg, Grand Duchy of Luxembourg, Luxembourg
Toxicol Lett 210:211-9. 2012..This represents a useful tool for the accurate biomonitoring of chronic exposure to PAH and correct identification of the sources of exposure...
Multi-class pesticide analysis in human hair by gas chromatography tandem (triple quadrupole) mass spectrometry with solid phase microextraction and liquid injectionGuillaume Salquebre
Laboratory of Analytical Human Biomonitoring CRP Santé, Université du Luxembourg, Luxembourg, Luxembourg
Anal Chim Acta 710:65-74. 2012..Altogether, 13 different analytes were detected at concentration above the limit of quantification...
Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in human hair by gas chromatography-negative chemical ionization mass spectrometryClaude Schummer
Laboratoire de Toxicologie, CRP Sante, Université du Luxembourg, Campus Limpertsberg, 1511 Luxembourg, Luxembourg
J Chromatogr A 1216:6012-9. 2009..According to the easiness of hair sampling and based on the extended detection windows provided by hair analysis, this method is proposed as a new promising tool for the assessment of human chronic exposure to PAHs...
Comparison of MTBSTFA and BSTFA in derivatization reactions of polar compounds prior to GC/MS analysisClaude Schummer
Centre de Geochimie de la Surface, UMR 7517, CNRS Université Louis Pasteur, Laboratoire de Physico Chimie de l Atmosphère, Strasbourg Cedex, France
Talanta 77:1473-82. 2009..Findings were confirmed with applications of both reagents to biological and environmental matrices (urine and atmospheric aerosols)...
Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants: state of the art, critical review and future needsBrice M R Appenzeller
Laboratory of Analytical Human Biomonitoring CRP Santé, Université du Luxembourg, 162A Avenue de la Faïencerie, L 1511 Luxembourg
Toxicol Lett 210:119-40. 2012..This study also presents a critical assessment of some specific aspects presented in the literature as well as future needs to strengthen the position of hair as a relevant biomarker of exposure to be used in epidemiological studies...
Reply to: A commentary on "Hair analysis for biomonitoring of environmental and occupational exposure to organic pollutants."Brice M R Appenzeller
Laboratory of Analytical Human Biomonitoring CRP Santé, Université du Luxembourg, 162A Avenue de la Faïencerie, L 1511, Luxembourg, Grand Duchy of Luxembourg
Toxicol Lett 210:265-6. 2012..We also remind some important aspects related to the use of hair as a biomarker of exposure to mercury...
Determination of PAHs and OH-PAHs in rat brain by gas chromatography tandem (triple quadrupole) mass spectrometryNathalie Grova
Laboratory of Analytical Human Biomonitoring CRP Santé, Université du Luxembourg, Campus Limpertsberg, 162A Avenue de la Faïencerie, Luxembourg
Chem Res Toxicol 24:1653-67. 2011..This study proves, for the first time, the bioavailability of most of the PAHs and OH-PAHs in mammalian brain tissue and should provide an important new tool for future neurotoxicological studies...
Relationship between blood alcohol concentration and carbohydrate-deficient transferrin among driversBrice M R Appenzeller
Centre de Recherche Public de la Santé, Laboratoire National de Santé, Division de Toxicologie, Université du Luxembourg, Campus Limpertsberg, 162A, avenue de la Faiencerie, L 1511 Luxembourg
Drug Alcohol Depend 79:261-5. 2005....
Altered distribution of transferrin isoforms according to serum storage conditionsBrice M R Appenzeller
Centre de Recherche Public-Sant, Laboratoire National de Sant, Toxicologie,
Clin Chem 51:2159-62. 2005
