A Fischer

Summary

Affiliation: Centre de Recherche Public-Sant
Country: Luxembourg

Publications

  1. pmc Simple DNA extraction method for dried blood spots and comparison of two PCR assays for diagnosis of vertical human immunodeficiency virus type 1 transmission in Rwanda
    A Fischer
    Retrovirology Laboratory, CRP Sante, Centre Hospitalier de Luxembourg, Luxembourg
    J Clin Microbiol 42:16-20. 2004
  2. ncbi request reprint Antiviral efficacy and resistance in patients on antiretroviral therapy in Kigali, Rwanda: the real-life situation in 2002
    A Fischer
    Centre Hospitalier de Luxembourg Retrovirology Laboratory, CRP Sante, Luxembourg
    HIV Med 7:64-6. 2006
  3. ncbi request reprint Four new adenosine deaminase mutations, altering a zinc-binding histidine, two conserved alanines, and a 5' splice site
    I Santisteban
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Hum Mutat 5:243-50. 1995
  4. ncbi request reprint The complex evolutionary history of gorillas: insights from genomic data
    O Thalmann
    Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 24:146-58. 2007
  5. ncbi request reprint Transcriptional up-regulation of histamine receptor-1 in epithelial, mucus and inflammatory cells in perennial allergic rhinitis
    Q T Dinh
    Department of Internal Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Allergy 35:1443-8. 2005
  6. ncbi request reprint [HIV-associated cerebral toxoplasmosis -- review and retrospective analysis of 36 patients]
    S Happe
    Abteilung Klinische Neurophysiologie, Georg August Universitat Gottingen
    Nervenarzt 73:1174-8. 2002
  7. ncbi request reprint Symptoms and HPV infection of the vulva: clinical manifestations or mere coincidence?
    B Ayer
    Cytology Department, Westmead Hospital, Sydney, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 41:443-6. 2001
  8. ncbi request reprint Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis
    F Altare
    Laboratoire de Genetique Humaine des Maladies Infectieuses, Universite Rene Descartes, INSERM U550, Faculte de Medecine Necker, Paris, France
    J Infect Dis 184:231-6. 2001
  9. pmc Expression and function of TrkB variants in developing sensory neurons
    N Ninkina
    School of Biological and Medical Sciences, University of St Andrews, UK
    EMBO J 15:6385-93. 1996
  10. pmc Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype
    I Santisteban
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    J Clin Invest 92:2291-302. 1993

Collaborators

  • J C Schmit
  • O Thalmann
  • Q T Dinh
  • S Happe
  • F Altare
  • B Ayer
  • F Lankester
  • L Vigilant
  • S Paabo
  • I Santisteban
  • S Dinh
  • S Wu
  • C Peiser
  • J Springer
  • B F Klapp
  • A Cryer
  • W Heppt
  • E Hamelmann
  • J P DiSanto
  • N Ninkina
  • St Evers
  • Ch Heese
  • U Gruneberg
  • M Freund
  • I W Husstedt
  • S Kloska
  • D Reichelt
  • B Spurrett
  • E Meinl
  • J E Baghdadi
  • A Ensser
  • A Breiman
  • J L Gaillard
  • J L Casanova
  • R Houghton
  • J Reichenbach
  • J F Emile
  • S Kelly
  • F X Arredondo-Vega
  • G de Saint Basile
  • L G Pinon
  • J Adu
  • A M Davies
  • V L Buchman
  • B Hilman
  • D H Dreyfus
  • J elDahr
  • E W Gelfand
  • J L Perignon
  • M Debre
  • A Dautry-Varsat
  • F Rieux-Laucat
  • R U Sorensen
  • J Y Bonnefoy
  • A Mary
  • L Uribe
  • J F Gauchat
  • A Lawton
  • D S Hummell
  • E R Stiehm

Detail Information

Publications13

  1. pmc Simple DNA extraction method for dried blood spots and comparison of two PCR assays for diagnosis of vertical human immunodeficiency virus type 1 transmission in Rwanda
    A Fischer
    Retrovirology Laboratory, CRP Sante, Centre Hospitalier de Luxembourg, Luxembourg
    J Clin Microbiol 42:16-20. 2004
    ..We conclude that this simple rapid DNA extraction method on DBS in combination with both detection methods gave a reliable molecular diagnosis of HIV-1 infection in children born to HIV-infected mothers...
  2. ncbi request reprint Antiviral efficacy and resistance in patients on antiretroviral therapy in Kigali, Rwanda: the real-life situation in 2002
    A Fischer
    Centre Hospitalier de Luxembourg Retrovirology Laboratory, CRP Sante, Luxembourg
    HIV Med 7:64-6. 2006
    ..Consequently the major objective for the ESTHER programme to improve the situation in Rwanda will be to reduce the drug shortage and facilitate the financial accessibility of the treatments...
  3. ncbi request reprint Four new adenosine deaminase mutations, altering a zinc-binding histidine, two conserved alanines, and a 5' splice site
    I Santisteban
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Hum Mutat 5:243-50. 1995
    ..Replacement of these small hydrophobic Ala residues with the charged, more bulky Asp side chain may distort ADA structure and affect enzyme stability or folding...
  4. ncbi request reprint The complex evolutionary history of gorillas: insights from genomic data
    O Thalmann
    Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany
    Mol Biol Evol 24:146-58. 2007
    ..9-1.6 MYA and subsequent, primarily male-mediated gene flow until approximately 80,000-200,000 years ago. Furthermore, simulations revealed that more gene flow took place from eastern to western gorilla populations than vice versa...
  5. ncbi request reprint Transcriptional up-regulation of histamine receptor-1 in epithelial, mucus and inflammatory cells in perennial allergic rhinitis
    Q T Dinh
    Department of Internal Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Allergy 35:1443-8. 2005
    ..The present study aimed to explore H1R and H2R expression in complex tissues of the nasal mucosa of perennial allergic rhinitis (PAR)...
  6. ncbi request reprint [HIV-associated cerebral toxoplasmosis -- review and retrospective analysis of 36 patients]
    S Happe
    Abteilung Klinische Neurophysiologie, Georg August Universitat Gottingen
    Nervenarzt 73:1174-8. 2002
    ..Indications and problems of stereotactic biopsy are discussed...
  7. ncbi request reprint Symptoms and HPV infection of the vulva: clinical manifestations or mere coincidence?
    B Ayer
    Cytology Department, Westmead Hospital, Sydney, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 41:443-6. 2001
    ..5% of asymptomatic women compared to 74% of symptomatic women (p = 0.007). This study suggests that vulvar symptoms are not clinical manifestations of HPV infection, but may be caused by dermatitis rather than HPV infection per se...
  8. ncbi request reprint Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis
    F Altare
    Laboratoire de Genetique Humaine des Maladies Infectieuses, Universite Rene Descartes, INSERM U550, Faculte de Medecine Necker, Paris, France
    J Infect Dis 184:231-6. 2001
    ..A diagnosis of IL-12Rbeta1 deficiency should therefore be considered in selected patients with severe tuberculosis, despite their resistance to BCG and a lack of atypical mycobacteriosis...
  9. pmc Expression and function of TrkB variants in developing sensory neurons
    N Ninkina
    School of Biological and Medical Sciences, University of St Andrews, UK
    EMBO J 15:6385-93. 1996
    ..Our results suggest that BDNF responsiveness in sensory neurons during development is modulated by the relative levels of catalytic and non-catalytic TrkB...
  10. pmc Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype
    I Santisteban
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710
    J Clin Invest 92:2291-302. 1993
    ..Tissue-specific variation in splicing efficiency may also ameliorate disease severity in patients with splicing mutations...
  11. ncbi request reprint CD40 ligand mutations in x-linked immunodeficiency with hyper-IgM
    J P DiSanto
    INSERM U 132, Hopital Necker Enfants Malades, Paris, France
    Nature 361:541-3. 1993
    ..These genetic alterations with abnormal CD40L expression provide a molecular basis for immunoglobulin isotype switch defects observed in this immunodeficiency...
  12. pmc Defective human interleukin 2 receptor gamma chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cells
    J P DiSanto
    Institut National de la Santé et de la Recherche Médicale U132, Hopital Necker Enfants Malades, Paris, France
    Proc Natl Acad Sci U S A 91:9466-70. 1994
    ..This atypical SCIDX1 patient demonstrates that certain IL-2R gamma chain abnormalities can also result in partial immunodeficiency phenotypes, potentially through differential effects on the IL-2, IL-4, or IL-7 receptor systems...
  13. ncbi request reprint Restriction-mediated differential display (RMDD)
    A Fischer
    F. Hoffmann-La Roche AG, Basel, Switzerland
    Curr Protoc Mol Biol . 2001
    ....