N J Diederich

Summary

Affiliation: Centre Hospitalier de Luxembourg
Country: Luxembourg

Publications

  1. doi request reprint Hallucinations in Parkinson disease
    Nico J Diederich
    Department of Neurology, Center Hospitalier de Luxembourg, 4 rue Barblé, Luxembourg City, Luxembourg
    Nat Rev Neurol 5:331-42. 2009
  2. ncbi request reprint Are patients with Parkinson's disease blind to blindsight?
    Nico J Diederich
    1 Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg2 Centre for Systems Biomedicine, University of Luxembourg, Esch Belval, Luxembourg3 Department of Neurological Sciences, Rush University Medical Centre, Chicago, USA
    Brain 137:1838-49. 2014
  3. doi request reprint Parkinson's disease: acquired frailty of archaic neural networks?
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    J Neurol Sci 314:143-51. 2012
  4. doi request reprint Ventral intermediate thalamic stimulation in complex tremor syndromes
    N J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Stereotact Funct Neurosurg 86:167-72. 2008
  5. ncbi request reprint Visual hallucinations and symptoms of REM sleep behavior disorder in Parkinsonian tauopathies
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Int J Geriatr Psychiatry 23:598-603. 2008
  6. doi request reprint Slow wave sleep and dopaminergic treatment in Parkinson's disease: a polysomnographic study
    N J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Acta Neurol Scand 120:308-13. 2009
  7. ncbi request reprint Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: a case report
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:1496-9. 2005
  8. ncbi request reprint Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:1413-8. 2005
  9. ncbi request reprint Progressive sleep 'destructuring' in Parkinson's disease. A polysomnographic study in 46 patients
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, 4, Rue Barble, L 1210 Luxembourg, Luxembourg
    Sleep Med 6:313-8. 2005
  10. doi request reprint Discriminative power of different nonmotor signs in early Parkinson's disease. A case-control study
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Mov Disord 25:882-7. 2010

Detail Information

Publications17

  1. doi request reprint Hallucinations in Parkinson disease
    Nico J Diederich
    Department of Neurology, Center Hospitalier de Luxembourg, 4 rue Barblé, Luxembourg City, Luxembourg
    Nat Rev Neurol 5:331-42. 2009
    ..The aim of this Review is to present epidemiological, phenomenological, pathophysiological and therapeutic aspects of hallucinations in PD...
  2. ncbi request reprint Are patients with Parkinson's disease blind to blindsight?
    Nico J Diederich
    1 Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg2 Centre for Systems Biomedicine, University of Luxembourg, Esch Belval, Luxembourg3 Department of Neurological Sciences, Rush University Medical Centre, Chicago, USA
    Brain 137:1838-49. 2014
    ....
  3. doi request reprint Parkinson's disease: acquired frailty of archaic neural networks?
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    J Neurol Sci 314:143-51. 2012
    ....
  4. doi request reprint Ventral intermediate thalamic stimulation in complex tremor syndromes
    N J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Stereotact Funct Neurosurg 86:167-72. 2008
    ..We report on deep brain stimulation (DBS) in the ventral intermediate part of the thalamus in 4 patients with complex tremor syndromes, 2 classified as Holmes tremor (HT) and 2 as thalamic tremor (TT)...
  5. ncbi request reprint Visual hallucinations and symptoms of REM sleep behavior disorder in Parkinsonian tauopathies
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Int J Geriatr Psychiatry 23:598-603. 2008
    ..In Parkinsonism, visual hallucinations (VH) and REM sleep behavior disorder (RBD) have been thought to indicate underlying synucleinopathy...
  6. doi request reprint Slow wave sleep and dopaminergic treatment in Parkinson's disease: a polysomnographic study
    N J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Acta Neurol Scand 120:308-13. 2009
    ..So far, there has been no study specifically investigating the influence of diurnal dopaminergic medication (DM) on nocturnal slow wave sleep (SWS)...
  7. ncbi request reprint Efficient internal pallidal stimulation in Gilles de la Tourette syndrome: a case report
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:1496-9. 2005
    ..Pronation/ supination bradykinesia of the left extremities was a well-tolerated, permanent side effect. Pallidal DBS could become a valuable rescue therapy for otherwise intractable GTS...
  8. ncbi request reprint Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:1413-8. 2005
    ..Longitudinal studies of patients with such "abortive" SAS are warranted to establish if this finding reflects benign nocturnal respiratory muscle dyskinesia or constitutes a precursor sign of dysautonomia in PD...
  9. ncbi request reprint Progressive sleep 'destructuring' in Parkinson's disease. A polysomnographic study in 46 patients
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, 4, Rue Barble, L 1210 Luxembourg, Luxembourg
    Sleep Med 6:313-8. 2005
    ..Sleep abnormalities in Parkinson's disease (PD) are frequent, but it is unknown whether or not there is progressive loss of physiological sleep architecture or what the causes could be...
  10. doi request reprint Discriminative power of different nonmotor signs in early Parkinson's disease. A case-control study
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg
    Mov Disord 25:882-7. 2010
    ..Visual deficits had the best discriminatory power. Being brief and inexpensive, visual tests should be further investigated in larger cohorts as potential screening tool for early PD...
  11. doi request reprint The placebo treatments in neurosciences: New insights from clinical and neuroimaging studies
    Nico J Diederich
    Department of Neurosciences, Centre Hospitalier de Luxembourg, 4, Rue Barble, L 1210 Luxembourg City, Luxembourg
    Neurology 71:677-84. 2008
    ..In depression, PL partially imitates selective serotonin reuptake inhibitor-mediated brain activation. Diseases lacking major "top-down" or cortically based regulation may be less prone to PL-related improvement...
  12. ncbi request reprint Parkinson disease with old-age onset: a comparative study with subjects with middle-age onset
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Arch Neurol 60:529-33. 2003
    ..To our knowledge, no prior study has focused on subjects with Parkinson disease (PD) with elderly disease onset, and there is little evidence-based knowledge of treatment outcomes in these patients...
  13. ncbi request reprint Camptocormia associated with focal myositis in multiple-system atrophy
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg
    Mov Disord 21:390-4. 2006
    ..The therapeutic response was poor. Similarities with the dropped-head syndrome suggest that the muscle pathology may be either the primary cause of CC, a focal reaction to the CC posture, or a coincident syndrome of old age...
  14. ncbi request reprint Cerebral acetylcholine esterase activity in mild cognitive impairment
    Karl Herholz
    Department of Neurology, University of Cologne, Koln, Germany
    Neuroreport 16:1431-4. 2005
    ..These results suggest that low cortical acetylcholine esterase activity may be an indicator of impending dementia in patients with mild cognitive impairment...
  15. ncbi request reprint Repeated visual hallucinations in Parkinson's disease as disturbed external/internal perceptions: focused review and a new integrative model
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 20:130-40. 2005
    ..This new conceptual framework permits an anatomical view of VH and suggests new, testable hypotheses regarding their pathophysiology and therapy...
  16. ncbi request reprint Coping strategies for visual hallucinations in Parkinson's disease
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, Luxembourg
    Mov Disord 18:831-2. 2003
    ..We found that 36 of our 46 Parkinson's disease subjects with hallucinations (78%) used coping strategies: cognitive techniques in 69%; interactive techniques in 62%; and visual techniques in 33%...
  17. ncbi request reprint Progressive worsening of spatial and chromatic processing deficits in Parkinson disease
    Nico J Diederich
    Department of Neuroscience, Centre Hospitalier de Luxembourg, 4 rue Barblé, L 1210 Luxembourg, Belgium
    Arch Neurol 59:1249-52. 2002
    ..Impairments of color discrimination (CD) and contrast sensitivity are established signs of Parkinson disease (PD), but their temporal evolution has not been studied...