Genomes and Genes


Eiliv Lund



  1. Lund E, Rasmussen Busund L, Thalabard J. Rethinking the carcinogenesis of breast cancer: The theory of breast cancer as a child deficiency disease or a pseudo semi-allograft. Med Hypotheses. 2018;120:76-80 pubmed publisher
    ..The theory of breast cancer as a child deficiency disease proposes that the protective effect of pregnancy on breast cancer incidence via the immune system is independent of other risk factors. ..
  2. Lund E, Plancade S, Nuel G, Bøvelstad H, Thalabard J. A processual model for functional analyses of carcinogenesis in the prospective cohort design. Med Hypotheses. 2015;85:494-7 pubmed publisher
    ..The processual approach as part of systems epidemiology might represent in a near future an alternative to human in vitro studies using human biological material for understanding the mechanisms and pathways involved in carcinogenesis. ..
  3. Bhoo Pathy N, Peeters P, Uiterwaal C, Bueno de Mesquita H, Bulgiba A, Bech B, et al. Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. Breast Cancer Res. 2015;17:15 pubmed publisher
    ..Higher caffeinated coffee intake may be associated with lower risk of postmenopausal breast cancer. Decaffeinated coffee intake does not seem to be associated with breast cancer. ..
  4. Merritt M, Riboli E, Murphy N, Kadi M, Tjønneland A, Olsen A, et al. Reproductive factors and risk of mortality in the European Prospective Investigation into Cancer and Nutrition; a cohort study. BMC Med. 2015;13:252 pubmed publisher
    ..These findings may contribute to the development of improved strategies to promote better long-term health in women. ..
  5. Bakken T, Braaten T, Olsen A, Kyrø C, Lund E, Skeie G. Consumption of Whole-Grain Bread and Risk of Colorectal Cancer among Norwegian Women (the NOWAC Study). Nutrients. 2016;8: pubmed publisher
    ..72-1.09) for the high consumption group and 0.86 (95% CI: 0.72-1.02) for the medium consumption group in a multivariable model. Overall, no association between whole-grain bread consumption and CRC was found. ..
  6. Lund E, Holden L, Bøvelstad H, Plancade S, Mode N, Günther C, et al. A new statistical method for curve group analysis of longitudinal gene expression data illustrated for breast cancer in the NOWAC postgenome cohort as a proof of principle. BMC Med Res Methodol. 2016;16:28 pubmed publisher
    ..When applied to a real data set it was able to discriminate between groups of genes with non-linear similar patterns before diagnosis. ..
  7. Jareid M, Thalabard J, Aarflot M, Bøvelstad H, Lund E, Braaten T. Levonorgestrel-releasing intrauterine system use is associated with a decreased risk of ovarian and endometrial cancer, without increased risk of breast cancer. Results from the NOWAC Study. Gynecol Oncol. 2018;149:127-132 pubmed publisher
    ..03 (0.91, 1.17), respectively. In this population-based prospective cohort study, ever users of LNG-IUS had a strongly reduced risk of ovarian and endometrial cancer compared to never users, with no increased risk of breast cancer. ..
  8. Lund E, Mode N, Waaseth M, Thalabard J. Overdiagnosis of breast cancer in the Norwegian Breast Cancer Screening Program estimated by the Norwegian Women and Cancer cohort study. BMC Cancer. 2013;13:614 pubmed publisher
    ..Naïve comparisons of screened and unscreened women may be affected by important differences in risk factors. The current challenge for the screening program is to improve the diagnostics used at prevalence screenings (ages 50-51). ..
  9. Borch K, Braaten T, Lund E, Weiderpass E. Physical activity before and after breast cancer diagnosis and survival - the Norwegian women and cancer cohort study. BMC Cancer. 2015;15:967 pubmed publisher
    ..Our results are very promising for women with breast cancer, and indicate that health care professionals should consider adding PA as a part of primary cancer treatment. ..

More Information


  1. Lund E, Nakamura A, Thalabard J. No overdiagnosis in the Norwegian Breast Cancer Screening Program estimated by combining record linkage and questionnaire information in the Norwegian Women and Cancer study. Eur J Cancer. 2018;89:102-112 pubmed publisher
    ..06). The findings of no significant overdiagnosis combined with smaller tumours and less lymph node metastases suggest that the prevailing view of overdiagnosis in the NBCSP should be challenged. ..
  2. Campa D, Husing A, McKay J, Sinilnikova O, Vogel U, Tjønneland A, et al. The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk. BMC Cancer. 2010;10:563 pubmed publisher