Joost Lumens

Summary

Publications

  1. pmc Comparative electromechanical and hemodynamic effects of left ventricular and biventricular pacing in dyssynchronous heart failure: electrical resynchronization versus left-right ventricular interaction
    Joost Lumens
    Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, L Institut de rythmologie et modélisation cardiaque LIRYC, Université Bordeaux, Bordeaux, France Maastricht University Medical Center, Cardiovascular Research Institute Maastricht CARIM, Maastricht, The Netherlands Electronic address
    J Am Coll Cardiol 62:2395-403. 2013
  2. ncbi request reprint Early-diastolic left ventricular lengthening implies pulmonary hypertension-induced right ventricular decompensation
    Joost Lumens
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, PO Box 616, Maastricht, 6200 MD, The Netherlands
    Cardiovasc Res 96:286-95. 2012
  3. ncbi request reprint Cardiovascular modeling in pulmonary arterial hypertension: focus on mechanisms and treatment of right heart failure using the CircAdapt model
    Joost Lumens
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, Netherlands
    Am J Cardiol 110:39S-48S. 2012
  4. ncbi request reprint Mechanistic evaluation of echocardiographic dyssynchrony indices: patient data combined with multiscale computer simulations
    Joost Lumens
    Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
    Circ Cardiovasc Imaging 5:491-9. 2012
  5. ncbi request reprint Right ventricular free wall pacing improves cardiac pump function in severe pulmonary arterial hypertension: a computer simulation analysis
    Joost Lumens
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, and Department of Cardiology, University Hospital Maastricht, Universiteitssingel 50, PO Box 616, 6200MR Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 297:H2196-205. 2009
  6. ncbi request reprint Left ventricular underfilling and not septal bulging dominates abnormal left ventricular filling hemodynamics in chronic thromboembolic pulmonary hypertension
    Joost Lumens
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 299:H1083-91. 2010
  7. ncbi request reprint Acute hemodynamic benefits of biventricular and single-site systemic ventricular pacing in patients with a systemic right ventricle
    Irene E van Geldorp
    Hopital Cardiologique du Haut Leveque, Bordeaux University Hospital, Bordeaux, France
    Heart Rhythm 10:676-82. 2013
  8. ncbi request reprint Noninvasive electrocardiographic mapping to improve patient selection for cardiac resynchronization therapy: beyond QRS duration and left bundle branch block morphology
    Sylvain Ploux
    Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, LIRYC, L Institut de rythmologie et modélisation cardiaque, Université de Bordeaux, Bordeaux, France
    J Am Coll Cardiol 61:2435-43. 2013
  9. ncbi request reprint Detailed analysis of ventricular activation sequences during right ventricular apical pacing and left bundle branch block and the potential implications for cardiac resynchronization therapy
    Romain Eschalier
    Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, Université Bordeaux, IHU LIRYC, Bordeaux, France Clermont Université, Université d Auvergne, CArdio Vascular Interventional Therapy and Imaging CaVITI, Image Science for Interventional Techniques ISIT, UMR6284, and CHU Clermont Ferrand, Cardiology Department, F 63003 Clermont Ferrand, France
    Heart Rhythm 12:137-43. 2015
  10. pmc Control of whole heart geometry by intramyocardial mechano-feedback: a model study
    Theo Arts
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    PLoS Comput Biol 8:e1002369. 2012

Detail Information

Publications15

  1. pmc Comparative electromechanical and hemodynamic effects of left ventricular and biventricular pacing in dyssynchronous heart failure: electrical resynchronization versus left-right ventricular interaction
    Joost Lumens
    Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, L Institut de rythmologie et modélisation cardiaque LIRYC, Université Bordeaux, Bordeaux, France Maastricht University Medical Center, Cardiovascular Research Institute Maastricht CARIM, Maastricht, The Netherlands Electronic address
    J Am Coll Cardiol 62:2395-403. 2013
    ....
  2. ncbi request reprint Early-diastolic left ventricular lengthening implies pulmonary hypertension-induced right ventricular decompensation
    Joost Lumens
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, PO Box 616, Maastricht, 6200 MD, The Netherlands
    Cardiovasc Res 96:286-95. 2012
    ..We hypothesized that this early-diastolic LVFW lengthening is caused by altered RVFW myofibre function and may therefore serve as a non-invasive measure of PH-induced RV (dys)function...
  3. ncbi request reprint Cardiovascular modeling in pulmonary arterial hypertension: focus on mechanisms and treatment of right heart failure using the CircAdapt model
    Joost Lumens
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, Netherlands
    Am J Cardiol 110:39S-48S. 2012
    ....
  4. ncbi request reprint Mechanistic evaluation of echocardiographic dyssynchrony indices: patient data combined with multiscale computer simulations
    Joost Lumens
    Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
    Circ Cardiovasc Imaging 5:491-9. 2012
    ..We investigated whether the variability of predictive power between the dyssynchrony indices can be explained by differences in their operational definitions...
  5. ncbi request reprint Right ventricular free wall pacing improves cardiac pump function in severe pulmonary arterial hypertension: a computer simulation analysis
    Joost Lumens
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, and Department of Cardiology, University Hospital Maastricht, Universiteitssingel 50, PO Box 616, 6200MR Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 297:H2196-205. 2009
    ..Thus our simulations indicate that, in decompensated PAH, RVfw pacing may improve RV pump function and may homogenize workload over the ventricular walls...
  6. ncbi request reprint Left ventricular underfilling and not septal bulging dominates abnormal left ventricular filling hemodynamics in chronic thromboembolic pulmonary hypertension
    Joost Lumens
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 299:H1083-91. 2010
    ..Thus, our simulations suggest that the increase of mitral E/A with PEA is caused two-thirds by an increase of RV output and one-third by the abolishment of leftward septal bulging...
  7. ncbi request reprint Acute hemodynamic benefits of biventricular and single-site systemic ventricular pacing in patients with a systemic right ventricle
    Irene E van Geldorp
    Hopital Cardiologique du Haut Leveque, Bordeaux University Hospital, Bordeaux, France
    Heart Rhythm 10:676-82. 2013
    ..Conventional nonsystemic ventricular pacing (non-systVP) may even further increase this risk...
  8. ncbi request reprint Noninvasive electrocardiographic mapping to improve patient selection for cardiac resynchronization therapy: beyond QRS duration and left bundle branch block morphology
    Sylvain Ploux
    Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, LIRYC, L Institut de rythmologie et modélisation cardiaque, Université de Bordeaux, Bordeaux, France
    J Am Coll Cardiol 61:2435-43. 2013
    ..This study sought to investigate whether noninvasive electrocardiographic activation mapping is a useful method for predicting response to cardiac resynchronization therapy (CRT)...
  9. ncbi request reprint Detailed analysis of ventricular activation sequences during right ventricular apical pacing and left bundle branch block and the potential implications for cardiac resynchronization therapy
    Romain Eschalier
    Hôpital Cardiologique du Haut Lévêque, CHU Bordeaux, Université Bordeaux, IHU LIRYC, Bordeaux, France Clermont Université, Université d Auvergne, CArdio Vascular Interventional Therapy and Imaging CaVITI, Image Science for Interventional Techniques ISIT, UMR6284, and CHU Clermont Ferrand, Cardiology Department, F 63003 Clermont Ferrand, France
    Heart Rhythm 12:137-43. 2015
    ..Whether right ventricular apical pacing (RVAP) produces similar ventricular activation patterns has not been well studied...
  10. pmc Control of whole heart geometry by intramyocardial mechano-feedback: a model study
    Theo Arts
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    PLoS Comput Biol 8:e1002369. 2012
    ..Different combinations of mechano-sensors satisfied the condition that control of geometry is stable. Thus, we expect that for various species, evolution may have selected different solutions for mechano-adaptation...
  11. ncbi request reprint Atrial septostomy benefits severe pulmonary hypertension patients by increase of left ventricular preload reserve
    Yvette Koeken
    Department of Biomedical Engineering, Maastricht University, Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 302:H2654-62. 2012
    ..This flow enhances left ventricular filling, allows blood pressure maintenance, but does not increase oxygen availability in the peripheral tissue...
  12. ncbi request reprint Influence of left ventricular lead position relative to scar location on response to cardiac resynchronization therapy: a model study
    Peter R Huntjens
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht, Maastricht University, Universiteitssingel 50, P O Box 616, 6229 ER Maastricht, The Netherlands
    Europace 16:iv62-iv68. 2014
    ..We investigated this complex interaction using a computational model...
  13. ncbi request reprint Mechano-electrical coupling as framework for understanding functional remodeling during LBBB and CRT
    Nico H L Kuijpers
    Department of Biomedical Engineering, Cardiovascular Research Institute Maastricht CARIM, Maastricht University, Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 306:H1644-59. 2014
    ..In conclusion, MEC may represent a useful framework for better understanding the long-term changes in cardiac electrophysiology and contraction following LBBB as well as CRT...
  14. ncbi request reprint Impaired subendocardial contractile myofiber function in asymptomatic aged humans, as detected using MRI
    Joost Lumens
    Dept of Biophysics, Cardiovascular Research Institute Maastricht, Maastricht Univ, PO Box 616, 6200 MD Maastricht, The Netherlands
    Am J Physiol Heart Circ Physiol 291:H1573-9. 2006
    ....
  15. pmc Three-wall segment (TriSeg) model describing mechanics and hemodynamics of ventricular interaction
    Joost Lumens
    Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Ann Biomed Eng 37:2234-55. 2009
    ....