Andrea Lukes

Summary

Publications

  1. doi request reprint Daily menstrual blood loss and quality of life in women with heavy menstrual bleeding
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    Womens Health (Lond Engl) 8:503-11. 2012
  2. doi request reprint Safety of tranexamic acid in women with heavy menstrual bleeding: an open-label extension study
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    Womens Health (Lond Engl) 7:591-8. 2011
  3. doi request reprint Improved premenstrual syndrome symptoms after NovaSure endometrial ablation
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    J Minim Invasive Gynecol 18:607-11. 2011
  4. doi request reprint Tranexamic acid: a novel oral formulation for the treatment of heavy menstrual bleeding
    Andrea S Lukes
    Rochester General Hospital, 1425 Portland Ave, Rochester, NY 14621, USA
    Womens Health (Lond Engl) 7:151-8. 2011
  5. doi request reprint Estimating a meaningful reduction in menstrual blood loss for women with heavy menstrual bleeding
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    Curr Med Res Opin 26:2673-8. 2010
  6. doi request reprint Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, North Carolina 27713, USA
    Obstet Gynecol 116:865-75. 2010
  7. ncbi request reprint Evolving issues in the clinical and managed care settings on the management of menopause following the women's health initiative
    Andrea Lukes
    Carolina Women s Research and Wellness Center, 110 Conner Dr, Chapel Hill, NC 27514, USA
    J Manag Care Pharm 14:7-13. 2008
  8. ncbi request reprint Use of the levonorgestrel-releasing intrauterine system in women with hemostatic disorders
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Chapel Hill, North Carolina 27514, USA
    Fertil Steril 90:673-7. 2008
  9. doi request reprint Multisite management study of menorrhagia with abnormal laboratory haemostasis: a prospective crossover study of intranasal desmopressin and oral tranexamic acid
    Peter A Kouides
    Mary M Gooley Hemophilia Center and the Rochester General Hospital, Rochester, NY 14621, USA
    Br J Haematol 145:212-20. 2009
  10. ncbi request reprint von Willebrand's disease diagnosed after menorrhagia worsened from levonorgestrel intrauterine system
    Andrea S Lukes
    Department of Obstetrics and Gynecology and Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Obstet Gynecol 105:1223-6. 2005

Detail Information

Publications16

  1. doi request reprint Daily menstrual blood loss and quality of life in women with heavy menstrual bleeding
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    Womens Health (Lond Engl) 8:503-11. 2012
    ....
  2. doi request reprint Safety of tranexamic acid in women with heavy menstrual bleeding: an open-label extension study
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    Womens Health (Lond Engl) 7:591-8. 2011
    ..An open-label, extension clinical study was conducted to assess the safety of a novel, oral formulation of tranexamic acid (TA) in women with cyclic heavy menstrual bleeding...
  3. doi request reprint Improved premenstrual syndrome symptoms after NovaSure endometrial ablation
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    J Minim Invasive Gynecol 18:607-11. 2011
    ..To evaluate the change in premenstrual syndrome (PMS) symptoms in women with heavy periods who underwent endometrial ablation...
  4. doi request reprint Tranexamic acid: a novel oral formulation for the treatment of heavy menstrual bleeding
    Andrea S Lukes
    Rochester General Hospital, 1425 Portland Ave, Rochester, NY 14621, USA
    Womens Health (Lond Engl) 7:151-8. 2011
    ..This article provides a summary of the clinical development, therapeutic efficacy and tolerability profile of this novel formulation of tranexamic acid for the treatment of HMB...
  5. doi request reprint Estimating a meaningful reduction in menstrual blood loss for women with heavy menstrual bleeding
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, NC 27713, USA
    Curr Med Res Opin 26:2673-8. 2010
    ..The purpose of this investigation was to correlate subjective and objective aspects of HMB treatment by identifying the minimum change in MBL that would be considered meaningful to women...
  6. doi request reprint Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, North Carolina 27713, USA
    Obstet Gynecol 116:865-75. 2010
    ..To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding...
  7. ncbi request reprint Evolving issues in the clinical and managed care settings on the management of menopause following the women's health initiative
    Andrea Lukes
    Carolina Women s Research and Wellness Center, 110 Conner Dr, Chapel Hill, NC 27514, USA
    J Manag Care Pharm 14:7-13. 2008
    ..This was true despite the fact that the WHI trial was a primary prevention study conducted in postmenopausal women and was not designed to evaluate the efficacy of HRT in the treatment of VMS...
  8. ncbi request reprint Use of the levonorgestrel-releasing intrauterine system in women with hemostatic disorders
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Chapel Hill, North Carolina 27514, USA
    Fertil Steril 90:673-7. 2008
    ..To evaluate the use of the levonorgestrel-releasing intrauterine system (LNG-IUS) in women with known hemostatic disorders and abnormal uterine bleeding...
  9. doi request reprint Multisite management study of menorrhagia with abnormal laboratory haemostasis: a prospective crossover study of intranasal desmopressin and oral tranexamic acid
    Peter A Kouides
    Mary M Gooley Hemophilia Center and the Rochester General Hospital, Rochester, NY 14621, USA
    Br J Haematol 145:212-20. 2009
    ..Use of both IN-DDAVP and TA improved QOL by all four instruments. We conclude that both medications reduced MBL and improved QOL among females with menorrhagia and abnormal laboratory haemostasis, but TA proved more effective...
  10. ncbi request reprint von Willebrand's disease diagnosed after menorrhagia worsened from levonorgestrel intrauterine system
    Andrea S Lukes
    Department of Obstetrics and Gynecology and Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Obstet Gynecol 105:1223-6. 2005
    ..Adult females with menorrhagia may have unrecognized mild von Willebrand's disease. Most females with known von Willebrand's disease report menorrhagia...
  11. ncbi request reprint Hemostasis and menstruation: appropriate investigation for underlying disorders of hemostasis in women with excessive menstrual bleeding
    Peter A Kouides
    Mary M Gooley Hemophilia Treatment Center, University of Rochester School of Medicine, Rochester, New York, USA
    Fertil Steril 84:1345-51. 2005
    ..This review highlights important components in a structured history and outlines primary and secondary hematologic testing that should be considered in the evaluation of excessive menstrual bleeding...
  12. ncbi request reprint Disorders of hemostasis and excessive menstrual bleeding: prevalence and clinical impact
    Andrea S Lukes
    Women s Hemostasis and Thrombosis Clinic, Duke University Medical Center, Durham, North Carolina 27710, USA
    Fertil Steril 84:1338-44. 2005
    ..The most common underlying bleeding disorder is von Willebrand disease, which occurs in only 1% to 2% of the general population but in approximately 13% of women with excessive menstrual bleeding...
  13. ncbi request reprint Use of a new platelet function analyzer to detect von Willebrand disease in women with menorrhagia
    Andra H James
    Department of Obstetrics and Gynecology, Division of Hematology, Duke University Medical Center, Durham, NC, USA
    Am J Obstet Gynecol 191:449-55. 2004
    ..The purpose of this study was to assess the usefulness of a new platelet function analyzer in the detection of von Willebrand disease and platelet dysfunction in women with menorrhagia...
  14. ncbi request reprint A benefit-risk review of systemic haemostatic agents: part 2: in excessive or heavy menstrual bleeding
    Ian S Fraser
    Department of Obstetrics and Gynaecology, University of Sydney, Sydney, NSW, Australia
    Drug Saf 31:275-82. 2008
    ..g. mefenamic acid) and combined estrogen/progestogen oral contraceptives. In patients with an underlying bleeding disorder (e.g. von Willebrand disease), an additional option is intranasal desmopressin...
  15. ncbi request reprint Abnormal uterine bleeding and underlying hemostatic disorders: report of a consensus process
    Malcolm G Munro
    Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA
    Fertil Steril 84:1335-7. 2005
    ....
  16. ncbi request reprint Hysterectomy versus expanded medical treatment for abnormal uterine bleeding: clinical outcomes in the medicine or surgery trial
    Andrea S Lukes
    Obstet Gynecol 104:864; author reply 864-5. 2004