Alexander N Lukashev

Summary

Publications

  1. Lukashev A, Drexler J, Belalov I, Eschbach Bludau M, Baumgarte S, Drosten C. Genetic variation and recombination in Aichi virus. J Gen Virol. 2012;93:1226-35 pubmed publisher
    ..While in most picornaviruses the genomic dinucleotide content contributed significantly to CUB, in AiV its extreme nucleotide content, i.e. 57?% third codon position C, was the main driving force behind the apparent CUB. ..
  2. Lukashev A, Zamyatnin A. Viral Vectors for Gene Therapy: Current State and Clinical Perspectives. Biochemistry (Mosc). 2016;81:700-8 pubmed publisher
    ..This review summarizes the latest trends in the development of gene therapy, in particular, various aspects and prospects of the development of clinical products based on viral delivery systems. ..
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    Lukashev A, Lashkevich V, Koroleva G, Ilonen J, Hinkkanen A. Recombination in uveitis-causing enterovirus strains. J Gen Virol. 2004;85:463-70 pubmed
    ..A full genome sequence comparison of the three subtypes of EU-causing strains excludes the role of recent recombination in their emergence, and points to their independent emergence...
  4. request reprint
    Lukashev A. Role of recombination in evolution of enteroviruses. Rev Med Virol. 2005;15:157-67 pubmed
    ..It remains to be determined what role recombination plays in the emergence of new enterovirus variants and in the macroevolution of animal enteroviruses and viruses of the picorna-like supergroup. ..
  5. Lukashev A, Ivanova O, Eremeeva T, Iggo R. Evidence of frequent recombination among human adenoviruses. J Gen Virol. 2008;89:380-8 pubmed publisher
    ..Comparison of the right end (nt 18838-33452) of this isolate with that of the ATCC Ad6 strain showed clear evidence of multiple recombination events...
  6. Lukashev A. Recombination among picornaviruses. Rev Med Virol. 2010;20:327-37 pubmed publisher
    ..This review covers existing evidence of recombination in most genera of the family Picornaviridae and possible implications for diagnostics, epidemiology and classification...
  7. Lukashev A, Drexler J, Kotova V, Amjaga E, Reznik V, Gmyl A, et al. Novel serotypes 105 and 116 are members of distinct subgroups of human enterovirus C. J Gen Virol. 2012;93:2357-62 pubmed publisher
    ..As there is also evidence of different permissive replication systems and distinct genetic properties of these subgroups, they may represent subspecies of the HEV-C species or different stages of speciation. ..

Locale

Detail Information

Publications7

  1. Lukashev A, Drexler J, Belalov I, Eschbach Bludau M, Baumgarte S, Drosten C. Genetic variation and recombination in Aichi virus. J Gen Virol. 2012;93:1226-35 pubmed publisher
    ..While in most picornaviruses the genomic dinucleotide content contributed significantly to CUB, in AiV its extreme nucleotide content, i.e. 57?% third codon position C, was the main driving force behind the apparent CUB. ..
  2. Lukashev A, Zamyatnin A. Viral Vectors for Gene Therapy: Current State and Clinical Perspectives. Biochemistry (Mosc). 2016;81:700-8 pubmed publisher
    ..This review summarizes the latest trends in the development of gene therapy, in particular, various aspects and prospects of the development of clinical products based on viral delivery systems. ..
  3. request reprint
    Lukashev A, Lashkevich V, Koroleva G, Ilonen J, Hinkkanen A. Recombination in uveitis-causing enterovirus strains. J Gen Virol. 2004;85:463-70 pubmed
    ..A full genome sequence comparison of the three subtypes of EU-causing strains excludes the role of recent recombination in their emergence, and points to their independent emergence...
  4. request reprint
    Lukashev A. Role of recombination in evolution of enteroviruses. Rev Med Virol. 2005;15:157-67 pubmed
    ..It remains to be determined what role recombination plays in the emergence of new enterovirus variants and in the macroevolution of animal enteroviruses and viruses of the picorna-like supergroup. ..
  5. Lukashev A, Ivanova O, Eremeeva T, Iggo R. Evidence of frequent recombination among human adenoviruses. J Gen Virol. 2008;89:380-8 pubmed publisher
    ..Comparison of the right end (nt 18838-33452) of this isolate with that of the ATCC Ad6 strain showed clear evidence of multiple recombination events...
  6. Lukashev A. Recombination among picornaviruses. Rev Med Virol. 2010;20:327-37 pubmed publisher
    ..This review covers existing evidence of recombination in most genera of the family Picornaviridae and possible implications for diagnostics, epidemiology and classification...
  7. Lukashev A, Drexler J, Kotova V, Amjaga E, Reznik V, Gmyl A, et al. Novel serotypes 105 and 116 are members of distinct subgroups of human enterovirus C. J Gen Virol. 2012;93:2357-62 pubmed publisher
    ..As there is also evidence of different permissive replication systems and distinct genetic properties of these subgroups, they may represent subspecies of the HEV-C species or different stages of speciation. ..