John D Lueck

Summary

Publications

  1. pmc Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle
    John D Lueck
    Department of Pharmacology and Physiology, and 2 Department of Neurology, University of Rochester, Rochester, NY 14642, USA
    J Gen Physiol 136:597-613. 2010
  2. pmc Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy
    John D Lueck
    Department of Physiology and Pharmacology, University of Rochester, Rochester, NY 14642, USA
    J Gen Physiol 129:79-94. 2007
  3. pmc Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy
    Thurman M Wheeler
    Department of Neurology, University of Rochester, Rochester, New York 14618, USA
    J Clin Invest 117:3952-7. 2007
  4. doi Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA
    Thurman M Wheeler
    Departments of Neurology, Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA
    Science 325:336-9. 2009
  5. ncbi Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1
    John D Lueck
    Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Am J Physiol Cell Physiol 292:C1291-7. 2007
  6. pmc Allele-specific gene silencing in two mouse models of autosomal dominant skeletal myopathy
    Ryan E Loy
    Department of Pharmacology and Physiology, University of Rochester, Rochester, New York, United States of America
    PLoS ONE 7:e49757. 2012

Collaborators

Detail Information

Publications6

  1. pmc Sarcolemmal-restricted localization of functional ClC-1 channels in mouse skeletal muscle
    John D Lueck
    Department of Pharmacology and Physiology, and 2 Department of Neurology, University of Rochester, Rochester, NY 14642, USA
    J Gen Physiol 136:597-613. 2010
    ..Collectively, these results demonstrate that the majority of functional ClC-1 channels localize to the sarcolemma and provide essential insight into the basis of myofiber excitability in normal and diseased skeletal muscle...
  2. pmc Muscle chloride channel dysfunction in two mouse models of myotonic dystrophy
    John D Lueck
    Department of Physiology and Pharmacology, University of Rochester, Rochester, NY 14642, USA
    J Gen Physiol 129:79-94. 2007
    ....
  3. pmc Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy
    Thurman M Wheeler
    Department of Neurology, University of Rochester, Rochester, New York 14618, USA
    J Clin Invest 117:3952-7. 2007
    ....
  4. doi Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA
    Thurman M Wheeler
    Departments of Neurology, Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA
    Science 325:336-9. 2009
    ..These findings suggest an alternative use of antisense methods, to inhibit deleterious interactions of proteins with pathogenic RNAs...
  5. ncbi Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1
    John D Lueck
    Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Am J Physiol Cell Physiol 292:C1291-7. 2007
    ....
  6. pmc Allele-specific gene silencing in two mouse models of autosomal dominant skeletal myopathy
    Ryan E Loy
    Department of Pharmacology and Physiology, University of Rochester, Rochester, New York, United States of America
    PLoS ONE 7:e49757. 2012
    ..As determined by quantitative real time PCR, the degree of functional rescue in YS/+ and IT/+ mice correlated well with the relative increase in fractional WT allele expression...