Jonas F Ludvigsson

Summary

Publications

  1. ncbi request reprint Coeliac disease and risk of sarcoidosis
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Sarcoidosis Vasc Diffuse Lung Dis 24:121-6. 2007
  2. doi request reprint Risk of lymphoproliferative malignancy in relation to small intestinal histopathology among patients with celiac disease
    Peter Elfström
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    J Natl Cancer Inst 103:436-44. 2011
  3. doi request reprint Small-intestinal histopathology and mortality risk in celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro 70185, Sweden
    JAMA 302:1171-8. 2009
  4. ncbi request reprint Risk of thromboembolism in 14,000 individuals with coeliac disease
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, and Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Br J Haematol 139:121-7. 2007
  5. doi request reprint Neutral risk of lung cancer in adults with celiac disease--nationwide cohort study
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, 701 85 Orebro, Sweden
    Lung Cancer 78:179-84. 2012
  6. doi request reprint Risk of thyroid disease in individuals with celiac disease
    Peter Elfström
    Department of Pediatrics, Orebro University Hospital, SE 701 85 Orebro, Sweden
    J Clin Endocrinol Metab 93:3915-21. 2008
  7. doi request reprint Psoriasis in a nationwide cohort study of patients with celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    J Invest Dermatol 131:2010-6. 2011
  8. ncbi request reprint Celiac disease and risk of liver disease: a general population-based study
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    Clin Gastroenterol Hepatol 5:63-69.e1. 2007
  9. pmc Validation study of villous atrophy and small intestinal inflammation in Swedish biopsy registers
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    BMC Gastroenterol 9:19. 2009
  10. pmc Primary hyperparathyroidism and celiac disease: a population-based cohort study
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, 701 85 Orebro, Sweden
    J Clin Endocrinol Metab 97:897-904. 2012

Detail Information

Publications57

  1. ncbi request reprint Coeliac disease and risk of sarcoidosis
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Sarcoidosis Vasc Diffuse Lung Dis 24:121-6. 2007
    ..Our main objective was to investigate the risk of subsequent sarcoidosis in individuals with CD in a general population cohort study. A second aim was to estimate the risk of CD in individuals with prior sarcoidosis...
  2. doi request reprint Risk of lymphoproliferative malignancy in relation to small intestinal histopathology among patients with celiac disease
    Peter Elfström
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    J Natl Cancer Inst 103:436-44. 2011
    ..The risk of lymphoproliferative malignancies in patients with small intestinal inflammation without villous atrophy and in patients with latent celiac disease is unknown...
  3. doi request reprint Small-intestinal histopathology and mortality risk in celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro 70185, Sweden
    JAMA 302:1171-8. 2009
    ..Studies of mortality in celiac disease have not taken small-intestinal pathology into account...
  4. ncbi request reprint Risk of thromboembolism in 14,000 individuals with coeliac disease
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, and Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    Br J Haematol 139:121-7. 2007
    ..27; 95% CI = 1.06-1.52). In conclusion, this study found a statistically significantly positive association between CD and VTE. This modest association might be explained by a combination of surveillance bias and chronic inflammation...
  5. doi request reprint Neutral risk of lung cancer in adults with celiac disease--nationwide cohort study
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, 701 85 Orebro, Sweden
    Lung Cancer 78:179-84. 2012
    ..Data on celiac disease (CD) and the risk of lung cancer are contradictory, with several studies suggesting a protective effect of CD. We investigated the future risk of lung cancer in individuals with biopsy-verified CD...
  6. doi request reprint Risk of thyroid disease in individuals with celiac disease
    Peter Elfström
    Department of Pediatrics, Orebro University Hospital, SE 701 85 Orebro, Sweden
    J Clin Endocrinol Metab 93:3915-21. 2008
    ..There is hence a need for further research. In this study, we estimated the risk of thyroid disease in individuals with celiac disease from a general population cohort...
  7. doi request reprint Psoriasis in a nationwide cohort study of patients with celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    J Invest Dermatol 131:2010-6. 2011
    ..91; 95% CI = 1.58-2.31). In conclusion, individuals with CD were at increased risk of psoriasis both before and after CD diagnosis...
  8. ncbi request reprint Celiac disease and risk of liver disease: a general population-based study
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    Clin Gastroenterol Hepatol 5:63-69.e1. 2007
    ..CD might also be associated with severe forms of liver disease. We investigated the risk of liver disease in 13,818 patients with CD (1964-2003) and 66,584 age- and sex-matched reference individuals from a general population cohort...
  9. pmc Validation study of villous atrophy and small intestinal inflammation in Swedish biopsy registers
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    BMC Gastroenterol 9:19. 2009
    ..Small intestinal biopsy with villous atrophy (VA) is the gold standard for the diagnosis of celiac disease (CD). We validated VA (Marsh 3) and small intestinal inflammation without VA (Marsh 1+2) in Swedish regional biopsy registers...
  10. pmc Primary hyperparathyroidism and celiac disease: a population-based cohort study
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, 701 85 Orebro, Sweden
    J Clin Endocrinol Metab 97:897-904. 2012
    ..Celiac disease (CD) has been linked to several endocrine disorders, including type 1 diabetes and thyroid disorders, but little is known regarding its association to primary hyperparathyroidism (PHPT)...
  11. ncbi request reprint Urinary tract infections in pregnant women with coeliac disease
    Ola Olén
    Department of Paediatrics, Stockholm Soder Hospital, Sweden
    Scand J Gastroenterol 42:186-93. 2007
    ..The objective of this study was to assess the risk of UTI and repeated episodes of UTI before the current pregnancy in women with diagnosed or undiagnosed CD...
  12. ncbi request reprint Smoking and celiac disease: a population-based cohort study
    Jonas F Ludvigsson
    Pediatric Department, Orebro University Hospital, Orebro, Sweden
    Clin Gastroenterol Hepatol 3:869-74. 2005
    ..Earlier studies indicate a protective effect of smoking against celiac disease (CD), but have been based on small numbers and retrospective collection of smoking data...
  13. ncbi request reprint Celiac disease and risk of adverse fetal outcome: a population-based cohort study
    Jonas F Ludvigsson
    Pediatric Department, Orebro University Hospital, Sweden
    Gastroenterology 129:454-63. 2005
    ..We investigated the risk of adverse outcomes in women with CD diagnosed prior to pregnancy and in women who did not receive a diagnosis of CD until after the delivery...
  14. ncbi request reprint Parental smoking and risk of coeliac disease in offspring
    Jonas F Ludvigsson
    Paediatric Department, Orebro University Hospital, Sweden
    Scand J Gastroenterol 40:336-42. 2005
    ..However, that study did not adjust for duration of exclusive breastfeeding, or look at passive smoking after birth...
  15. ncbi request reprint Celiac disease and risk of subsequent type 1 diabetes: a general population cohort study of children and adolescents
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro 701 85, Sweden
    Diabetes Care 29:2483-8. 2006
    ..We sought to determine the risk of subsequent type 1 diabetes diagnosed before the age of 20 years in children and adolescents with celiac disease in a national, general population-based cohort...
  16. pmc Increasing incidence of celiac disease in a north american population
    Jonas F Ludvigsson
    1 Division of Gastroenterology and Hepatology, Departments of Medicine and Immunology, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA 2 Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    Am J Gastroenterol 108:818-24. 2013
    ..Previous reports indicate that the incidence of CD is increasing. We examined the prevalence of CD in a well-defined US county...
  17. doi request reprint Risk of stroke in 28,000 patients with celiac disease: a nationwide cohort study in Sweden
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    J Stroke Cerebrovasc Dis 21:860-7. 2012
    ..We examined the risk of stroke in patients with biopsy-verified CD...
  18. ncbi request reprint Coeliac disease and risk of mood disorders--a general population-based cohort study
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    J Affect Disord 99:117-26. 2007
    ..Earlier research has indicated a positive association between coeliac disease (CD) and some mental disorders. Studies on CD and depression have inconsistent findings and we know of no study of CD and the risk of bipolar disorder (BD)...
  19. ncbi request reprint Coeliac disease and risk of renal disease-a general population cohort study
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Nephrol Dial Transplant 21:1809-15. 2006
    ..Coeliac disease (CD) may be a risk factor for renal disease...
  20. ncbi request reprint Risk of primary adrenal insufficiency in patients with celiac disease
    Peter Elfström
    Department of Pediatrics, Orebro University Hospital, SE 701 85 Orebro, Sweden
    J Clin Endocrinol Metab 92:3595-8. 2007
    ..Earlier research has suggested a positive association between Addison's disease (AD) and celiac disease (CD). We have here investigated the risk of AD in individuals with CD from a general population cohort...
  21. ncbi request reprint Socio-economic determinants, maternal smoking and coffee consumption, and exclusive breastfeeding in 10205 children
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Acta Paediatr 94:1310-9. 2005
    ..To examine socio-economic factors, smoking, coffee consumption and exclusive breastfeeding duration...
  22. ncbi request reprint Coeliac disease and risk of schizophrenia and other psychosis: a general population cohort study
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Scand J Gastroenterol 42:179-85. 2007
    ..The objective of our study was to determine the risk of non-affective psychosis in patients with CD in a national general population cohort...
  23. ncbi request reprint Risk of pancreatitis in 14,000 individuals with celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Linkoping, Sweden
    Clin Gastroenterol Hepatol 5:1347-53. 2007
    ..The aim of this study was to examine the risk of pancreatitis in patients with celiac disease (CD) from a general population cohort...
  24. pmc Symptoms and signs in individuals with serology positive for celiac disease but normal mucosa
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Sweden
    BMC Gastroenterol 9:57. 2009
    ..In this study we describe a model for identifying and characterizing individuals with normal mucosa but positive CD serology. Such individuals are sometimes referred to as having latent CD...
  25. doi request reprint Nationwide cohort study of risk of ischemic heart disease in patients with celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    Circulation 123:483-90. 2011
    ..Studies on ischemic heart disease (IHD) incidence in individuals with celiac disease (CD) are contradictory and do not take small intestinal pathology into account...
  26. doi request reprint Increased suicide risk in coeliac disease--a Swedish nationwide cohort study
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Dig Liver Dis 43:616-22. 2011
    ..We examined the risk of suicide in coeliac disease and amongst individuals where the small intestinal biopsy showed no villous atrophy...
  27. doi request reprint A nationwide population-based study to determine whether coeliac disease is associated with infertility
    Daniela Zugna
    Department of Paediatrics, Orebro University Hospital, Orebro, Sweden
    Gut 59:1471-5. 2010
    ..12 (95% CI 1.03 to 1.21) thereafter. Conclusion Overall, women with CD had a normal fertility, but their fertility was decreased in the last 2 years preceding CD diagnosis...
  28. ncbi request reprint Epidemiological study of constipation and other gastrointestinal symptoms in 8000 children
    Jonas F Ludvigsson
    Paediatric Department, Orebro University Hospital, Sweden
    Acta Paediatr 95:573-80. 2006
    ..Adult studies indicate that gastrointestinal symptoms vary with sex and socioeconomic status. We examined socioeconomic factors, infant sex, smoking and gastrointestinal symptoms, especially constipation, in 2.5 year-old children...
  29. pmc Does hemochromatosis predispose to celiac disease? A study of 29,096 celiac disease patients
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    Scand J Gastroenterol 48:176-82. 2013
    ..Case reports suggest an association between hereditary hemochromatosis (HH) and celiac disease (CD), but estimates of association are lacking. We estimated the association between HH and CD in a population-based study...
  30. pmc The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Orebro, Sweden
    Eur J Epidemiol 24:659-67. 2009
    ..We suggest that matching of registers through PIN and matching of national health registers without the explicit approval of the individual patient is to the benefit for both the individual patient and for society...
  31. ncbi request reprint Breastfeeding and introduction of solid foods in Swedish infants: the All Babies in Southeast Sweden study
    Hilde K Brekke
    Department of Clinical Nutrition, Sahlgrenska Academy at Goteborg University, and Paediatric Department, Orebro University Hospital, Sweden
    Br J Nutr 94:377-82. 2005
    ..The adherence to allergy-preventive advice was less than optimal in infants with atopic heredity...
  32. pmc External review and validation of the Swedish national inpatient register
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Sweden
    BMC Public Health 11:450. 2011
    ..A previous validation of the IPR by the National Board of Health and Welfare showed that 85-95% of all diagnoses in the IPR are valid. The current paper describes the history, structure, coverage and quality of the Swedish IPR...
  33. doi request reprint Increased risk of IgA nephropathy among individuals with celiac disease
    Adina Welander
    Clinical Epidemiology Unit, Department of Medicine Department of Pathology, Karolinska University Hospital, Stockholm Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    J Clin Gastroenterol 47:678-83. 2013
    ..To determine the risk of future biopsy-verified IgA nephropathy (IgAN) among individuals with biopsy-verified celiac disease (CD)...
  34. pmc Season of birth in a nationwide cohort of coeliac disease patients
    Benjamin Lebwohl
    Coeliac Disease Center, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, USA
    Arch Dis Child 98:48-51. 2013
    ..Children born in summer months are likely to be weaned and introduced to gluten during winter when viral infections are more frequent. Earlier studies on birth season and CD are limited in sample size and results are contradictory...
  35. ncbi request reprint Symptoms and signs have changed in Swedish children with coeliac disease
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Orebro, Sweden
    J Pediatr Gastroenterol Nutr 38:181-6. 2004
    ..This project was part of the ABIS study (All Babies in Southeast Sweden, born from October 1997 to October 1999)...
  36. ncbi request reprint Effect of HLA DQ2, dietary exposure and coeliac disease on the development of antibody response to gliadin in children
    Jonas F Ludvigsson
    Paediatric Department, Orebro University Hospital, Sweden
    Scand J Gastroenterol 41:919-28. 2006
    ..5 years of age in children who developed CD and in healthy children...
  37. ncbi request reprint Exclusive breastfeeding and risk of atopic dermatitis in some 8300 infants
    Jonas F Ludvigsson
    Department of Paediatrics, Orebro University Hospital, Orebro, Sweden
    Pediatr Allergy Immunol 16:201-8. 2005
    ..76; 95% CI AOR = 0.61-0.95; p = 0.016). This study indicates that exclusive breastfeeding does not influence the risk of AD during the first year of life, while presence of furred pets at home seems to be negatively associated with AD...
  38. doi request reprint Mortality and malignancy in celiac disease
    Jonas F Ludvigsson
    Department of Pediatrics, Orebro University Hospital, Orebro, Sweden
    Gastrointest Endosc Clin N Am 22:705-22. 2012
    ..The evidence that a GFD reduces the risk of mortality is weak, but there is some evidence suggesting that a GFD may reduce the risk of lymphoproliferative malignancy...
  39. pmc Pregnancy outcome and risk of celiac disease in offspring: a nationwide case-control study
    Karl Mårild
    Astrid Lindgren Children s Hospital, Solna, Sweden
    Gastroenterology 142:39-45.e3. 2012
    ..In recent decades rates of cesarean delivery and preterm birth survival have increased while at the same time the prevalence of celiac disease has doubled...
  40. ncbi request reprint [Do not treat interns-researchers unfairly!]
    Jonas F Ludvigsson
    Barnkliniken, Universitetssjukhuset i Orebro
    Lakartidningen 100:3162, 3165. 2003
  41. ncbi request reprint [Shortly about cohort studies]
    Jonas F Ludvigsson
    Barnkliniken, Universitetssjukhuset Orebro
    Lakartidningen 103:943-4. 2006
  42. ncbi request reprint Coeliac disease in the father and risk of adverse pregnancy outcome: a population-based cohort study
    Jonas F Ludvigsson
    Pediatric Department Orebro University Hospital, Sweden
    Scand J Gastroenterol 41:178-85. 2006
    ..The risk of adverse foetal outcomes was investigated in offspring to men with coeliac disease (CD) diagnosed prior to infant birth and in offspring to men who did not receive a diagnosis of CD until after the delivery...
  43. ncbi request reprint Risk factors in childhood obesity-findings from the All Babies In Southeast Sweden (ABIS) cohort
    Karina Huus
    Division of Pediatrics and Diabetes Research Centre, Linkoping University, Sweden
    Acta Paediatr 96:1321-5. 2007
    ....
  44. ncbi request reprint [Three books on one CD-ROM. ICDplus--software for searching classification codes]
    Jonas F Ludvigsson
    Barnkliniken, Regionsjukhuset i Orebro
    Lakartidningen 99:307-8. 2002
  45. ncbi request reprint [Palm computer--a mini notebook for physicians]
    Jonas F Ludvigsson
    Barnkliniken, Universitetssjukhuset, Orebro
    Lakartidningen 99:1473-6. 2002
  46. pmc Breastfeeding in Bolivia - information and attitudes
    Jonas F Ludvigsson
    Pediatric Department, Orebro University Hospital, Orebro, Sweden
    BMC Pediatr 3:4. 2003
    ..A second objective was to study the relationship between breastfeeding information, specified according to source and timing, and feeding pattern...
  47. ncbi request reprint [Regular palm computer with many useful functions for health personnel]
    Jonas F Ludvigsson
    Barnkliniken, Universitetssjukhuset, Orebro
    Lakartidningen 99:1477-8. 2002
  48. ncbi request reprint [Filemaker Pro 7--useful database software]
    Jonas F Ludvigsson
    Enheten för Klinisk Epidemiologi, Karolinska Universitetssjukhuset Solna
    Lakartidningen 102:2418-9. 2005
  49. ncbi request reprint [A software for physicians with mobile offices]
    Jonas F Ludvigsson
    Barnkliniken, Universitetssjukhuset, Orebro
    Lakartidningen 99:1479-80. 2002
  50. ncbi request reprint [Health information on the Internet. Quality stamps don't live upp to their names]
    Jonas F Ludvigsson
    Universitetssjukhuset, Orebro
    Lakartidningen 99:3714-5. 2002
  51. ncbi request reprint [Computer programs as a tool for creation of "mind maps". Tested study technique now in an electronic version]
    Jonas F Ludvigsson
    Barnkliniken, Orebro
    Lakartidningen 99:4284-5. 2002
  52. pmc Breastfeeding intentions, patterns, and determinants in infants visiting hospitals in La Paz, Bolivia
    Jonas F Ludvigsson
    Paediatric Department, Orebro University Hospital, 701 85 Orebro, Sweden
    BMC Pediatr 3:5. 2003
    ..Recent ecological research from Latin America has shown that infant health could be promoted through exclusive breastfeeding in infants aged 0-3 months and partial breastfeeding throughout the remainder of infancy...
  53. ncbi request reprint [Insufficient health information on Internet. Physicians are still necessary as intermediaries and interpreters of the information]
    Jonas F Ludvigsson
    Barnkliniken, Regionsjukhuset, Orebro
    Lakartidningen 99:306-7. 2002
  54. ncbi request reprint Recruiters and academia. Hard times for Swedish physician-researchers
    Jonas F Ludvigsson
    Orebro University Hospital in Sweden
    Nature 434:542. 2005
  55. doi request reprint Increased risk of immune thrombocytopenic purpura among inpatients with coeliac disease
    Ola Olén
    Sachs Children s Hospital, Stockholm South General Hospital, Sweden
    Scand J Gastroenterol 43:416-22. 2008
    ..Case reports have indicated a link between coeliac disease (CD) and immune thrombocytopenic purpura (ITP). Two national, register-based studies were carried out to investigate a possible association between CD and ITP and vice versa...
  56. pmc Coeliac disease: Decision tool needs to be developed for children
    Jonas F Ludvigsson
    BMJ 334:864. 2007
  57. ncbi request reprint RAR-related orphan receptor A isoform 1 (RORa1) is disrupted by a balanced translocation t(4;15)(q22.3;q21.3) associated with severe obesity
    Joakim Klar
    Department of Genetics and Pathology, The Rudbeck Laboratory, Uppsala University, Sweden
    Eur J Hum Genet 13:928-34. 2005
    ..We hypothesise that the obesity in this family is caused by (i) haploinsufficiency for RORa1 or, (ii) a gain of function mechanism mediated by the RORa1-UNC5C fusion gene...