Gérard Lucotte

Summary

Publications

  1. Lucotte G, Dieterlen F. More about the Viking hypothesis of origin of the delta32 mutation in the CCR5 gene conferring resistance to HIV-1 infection. Infect Genet Evol. 2003;3:293-5 pubmed
    ..We constructed an allele map of delta32 frequencies in Europe; the map is in accordance to the Vikings hypothesis of the origin of the mutation and his dissemination during the eighth to the tenth centuries. ..
  2. Lucotte G, Dieterlen F. A European allele map of the C282Y mutation of hemochromatosis: Celtic versus Viking origin of the mutation?. Blood Cells Mol Dis. 2003;31:262-7 pubmed
    ..The highest European frequencies are observed in the Celtic populations in Ireland, in the United Kingdom, and in France, but elevated frequencies are also observed in Scandinavia. ..
  3. Lucotte G, Smets P. CCR5-Delta32 allele frequencies in Ashkenazi Jews. Genet Test. 2003;7:333-7 pubmed
    ..20, p < 0.03). Founder effect and genetic drift are proposed to explain the elevated values observed in Ashkenazi Jews and those originating from Lithuania. ..
  4. Lucotte G, Houzet A, Hubans C, Lagarde J, Lenoir G. Mutations of the noggin (NOG) and of the activin A type I receptor (ACVR1) genes in a series of twenty-seven French fibrodysplasia ossificans progressiva (FOP) patients. Genet Couns. 2009;20:53-62 pubmed
    ..Mutations 274G>C, 283G>A and 617G>A segregate with the trait in five different FOP families, some members of them being partially affected by the disease. ..
  5. Lucotte G, Mercier G, Dieterlen F, Yuasa I. A decreasing gradient of 374F allele frequencies in the skin pigmentation gene SLC45A2, from the north of West Europe to North Africa. Biochem Genet. 2010;48:26-33 pubmed publisher
    ..869). The results confirm that the distribution of the 374F allele may reflect the ultraviolet radiation level and can be associated with skin color variation in these regions. ..
  6. Lucotte G, Yuasa I. Near fixation of 374l allele frequencies of the skin pigmentation gene SLC45A2 in Africa. Biochem Genet. 2013;51:655-65 pubmed publisher
    ..Almost all the African populations located below 16° of latitude are fixed for the 374l allele. Peul, Toucouleur, and Soninké populations have 374l allele frequencies of 0.06, 0.03, and 0.03, respectively. ..

Locale

Detail Information

Publications6

  1. Lucotte G, Dieterlen F. More about the Viking hypothesis of origin of the delta32 mutation in the CCR5 gene conferring resistance to HIV-1 infection. Infect Genet Evol. 2003;3:293-5 pubmed
    ..We constructed an allele map of delta32 frequencies in Europe; the map is in accordance to the Vikings hypothesis of the origin of the mutation and his dissemination during the eighth to the tenth centuries. ..
  2. Lucotte G, Dieterlen F. A European allele map of the C282Y mutation of hemochromatosis: Celtic versus Viking origin of the mutation?. Blood Cells Mol Dis. 2003;31:262-7 pubmed
    ..The highest European frequencies are observed in the Celtic populations in Ireland, in the United Kingdom, and in France, but elevated frequencies are also observed in Scandinavia. ..
  3. Lucotte G, Smets P. CCR5-Delta32 allele frequencies in Ashkenazi Jews. Genet Test. 2003;7:333-7 pubmed
    ..20, p < 0.03). Founder effect and genetic drift are proposed to explain the elevated values observed in Ashkenazi Jews and those originating from Lithuania. ..
  4. Lucotte G, Houzet A, Hubans C, Lagarde J, Lenoir G. Mutations of the noggin (NOG) and of the activin A type I receptor (ACVR1) genes in a series of twenty-seven French fibrodysplasia ossificans progressiva (FOP) patients. Genet Couns. 2009;20:53-62 pubmed
    ..Mutations 274G>C, 283G>A and 617G>A segregate with the trait in five different FOP families, some members of them being partially affected by the disease. ..
  5. Lucotte G, Mercier G, Dieterlen F, Yuasa I. A decreasing gradient of 374F allele frequencies in the skin pigmentation gene SLC45A2, from the north of West Europe to North Africa. Biochem Genet. 2010;48:26-33 pubmed publisher
    ..869). The results confirm that the distribution of the 374F allele may reflect the ultraviolet radiation level and can be associated with skin color variation in these regions. ..
  6. Lucotte G, Yuasa I. Near fixation of 374l allele frequencies of the skin pigmentation gene SLC45A2 in Africa. Biochem Genet. 2013;51:655-65 pubmed publisher
    ..Almost all the African populations located below 16° of latitude are fixed for the 374l allele. Peul, Toucouleur, and Soninké populations have 374l allele frequencies of 0.06, 0.03, and 0.03, respectively. ..