John M Luce

Summary

Publications

  1. ncbi request reprint Perspectives on care at the close of life. Management of dyspnea in patients with far-advanced lung disease: "once I lose it, it's kind of hard to catch it... "
    J M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, 1001 Potrero Ave, Room 5K1, San Francisco, CA 94110, USA
    JAMA 285:1331-7. 2001
  2. ncbi request reprint Can health care costs be reduced by limiting intensive care at the end of life?
    John M Luce
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Respir Crit Care Med 165:750-4. 2002
  3. ncbi request reprint Corticosteroids in ARDS. An evidence-based review
    John M Luce
    Department of Medicine and Anesthesia, University of California, Medical Surgical Intensive Care Unit, San Francisco General Hospital, San Francisco, California, USA
    Crit Care Clin 18:79-89, vii. 2002
  4. pmc Hope, truth, and preparing for death: perspectives of surrogate decision makers
    Latifat Apatira
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143, USA
    Ann Intern Med 149:861-8. 2008
  5. doi request reprint A history of resolving conflicts over end-of-life care in intensive care units in the United States
    John M Luce
    Department of Medicine and Anesthesia, University of California, San Francisco, and San Francisco General Hospital, San Francisco, CA, USA
    Crit Care Med 38:1623-9. 2010
  6. ncbi request reprint Life support for patients without a surrogate decision maker: who decides?
    Douglas B White
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143 0903, USA
    Ann Intern Med 147:34-40. 2007
  7. doi request reprint End-of-life decision making in the intensive care unit
    John M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, 1001 Potrero Avenue, Room 5K1, San Francisco, CA 94110, USA
    Am J Respir Crit Care Med 182:6-11. 2010
  8. ncbi request reprint Decisions to limit life-sustaining treatment for critically ill patients who lack both decision-making capacity and surrogate decision-makers
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Crit Care Med 34:2053-9. 2006
  9. pmc A history of ethics and law in the intensive care unit
    John M Luce
    Department of Medicine, University of California, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care Clin 25:221-37, x. 2009
  10. pmc Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debate
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
    Am J Respir Crit Care Med 180:320-5. 2009

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Perspectives on care at the close of life. Management of dyspnea in patients with far-advanced lung disease: "once I lose it, it's kind of hard to catch it... "
    J M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, 1001 Potrero Ave, Room 5K1, San Francisco, CA 94110, USA
    JAMA 285:1331-7. 2001
    ..Physicians should encourage end-stage lung disease patients and their families to discuss issues such as hospitalization and mechanical ventilation, to prepare advance directives, and to participate in a plan to manage their dyspnea...
  2. ncbi request reprint Can health care costs be reduced by limiting intensive care at the end of life?
    John M Luce
    Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Am J Respir Crit Care Med 165:750-4. 2002
  3. ncbi request reprint Corticosteroids in ARDS. An evidence-based review
    John M Luce
    Department of Medicine and Anesthesia, University of California, Medical Surgical Intensive Care Unit, San Francisco General Hospital, San Francisco, California, USA
    Crit Care Clin 18:79-89, vii. 2002
    ....
  4. pmc Hope, truth, and preparing for death: perspectives of surrogate decision makers
    Latifat Apatira
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143, USA
    Ann Intern Med 149:861-8. 2008
    ..Although many physicians worry that openly discussing a poor prognosis will cause patients and families to lose hope, surrogate decision makers' perspectives on this topic are largely unknown...
  5. doi request reprint A history of resolving conflicts over end-of-life care in intensive care units in the United States
    John M Luce
    Department of Medicine and Anesthesia, University of California, San Francisco, and San Francisco General Hospital, San Francisco, CA, USA
    Crit Care Med 38:1623-9. 2010
    ..To present a case of conflict over end-of-life care in the intensive care unit (ICU) and to describe how such conflicts have been resolved in the United States since the inception of ICUs...
  6. ncbi request reprint Life support for patients without a surrogate decision maker: who decides?
    Douglas B White
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143 0903, USA
    Ann Intern Med 147:34-40. 2007
    ..Physicians in intensive care units have withdrawn life support in incapacitated patients who lack surrogate decision makers and advance directives, yet little is known about how often this occurs or under what circumstances...
  7. doi request reprint End-of-life decision making in the intensive care unit
    John M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, 1001 Potrero Avenue, Room 5K1, San Francisco, CA 94110, USA
    Am J Respir Crit Care Med 182:6-11. 2010
    ..Ethics committees actually are allowed to make such decisions in one state when disagreements cannot be resolved otherwise...
  8. ncbi request reprint Decisions to limit life-sustaining treatment for critically ill patients who lack both decision-making capacity and surrogate decision-makers
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Crit Care Med 34:2053-9. 2006
    ..We sought to determine how often such patients are admitted to the ICU of a metropolitan hospital and how end-of-life decisions are made for them...
  9. pmc A history of ethics and law in the intensive care unit
    John M Luce
    Department of Medicine, University of California, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care Clin 25:221-37, x. 2009
    ..Advancement of the ethical principle of respect for patient autonomy in ICUs increasingly is in conflict with physicians' concern about their own prerogatives and with the just distribution of medical resources...
  10. pmc Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debate
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
    Am J Respir Crit Care Med 180:320-5. 2009
    ..Although there is a growing belief that physicians should routinely provide a recommendation to surrogates during deliberations about withdrawing life support, there is a paucity of empirical data on surrogates' perspectives on this topic...
  11. pmc Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertainty
    Leah R Evans
    Division of Pulmonary and Critical Care Medicine, University of California School of Medicine, San Francisco, California 94143 0903, USA
    Am J Respir Crit Care Med 179:48-53. 2009
    ..Many physicians are reluctant to discuss a patient's prognosis when there is significant prognostic uncertainty...
  12. pmc The pressure to withhold or withdraw life-sustaining therapy from critically ill patients in the United States
    John M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, 1001 Potrero Avenue, Room 5 K1, San Francisco, CA 94110, USA
    Am J Respir Crit Care Med 175:1104-8. 2007
    ..The pressure also may damage communications and cause resentment. If communications cannot be improved, and if the pressure cannot be relieved, a due process approach to conflict resolution that involves other parties may be required...
  13. pmc Who should receive life support during a public health emergency? Using ethical principles to improve allocation decisions
    Douglas B White
    Program in Medical Ethics, School of Medicine, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0903, USA
    Ann Intern Med 150:132-8. 2009
    ..We discuss strategies to engage the public in setting the priorities that will guide allocation of scarce life-sustaining treatments during a public health emergency...
  14. ncbi request reprint Intrinsic positive end-expiratory pressure in Acute Respiratory Distress Syndrome (ARDS) Network subjects
    Catherine Lee Hough
    Division of Pulmonary and Critical Care Medicine, Department of Medicine at the University of Washington, Seattle, WA, USA
    Crit Care Med 33:527-32. 2005
    ....
  15. pmc Doubt and belief in physicians' ability to prognosticate during critical illness: the perspective of surrogate decision makers
    Lucas S Zier
    UC Berkeley UC San Francisco Joint Medical Program, School of Public Health, University of California, Berkeley, CA, USA
    Crit Care Med 36:2341-7. 2008
    ..We sought to determine: 1) surrogates' beliefs about whether physicians can accurately prognosticate for critically ill patients; and 2) how individuals use prognostic information in their role as surrogate decision-makers...
  16. ncbi request reprint Research ethics and consent in the intensive care unit
    John M Luce
    Medical and Surgical Intensive Care Units, San Francisco General Hospital, University of California, San Francisco, California 94110, USA
    Curr Opin Crit Care 9:540-4. 2003
    ..The subject of research ethics and informed consent in the ICU has recently received unprecedented attention during the past year, the reasons for which are reviewed herein...
  17. doi request reprint Informed consent for clinical research involving patients with chest disease in the United States
    John M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    Chest 135:1061-8. 2009
    ..Consent can be deferred or waived for emergency research only rarely in the United States, in contrast to other countries...
  18. ncbi request reprint Protecting subjects with decisional impairment in research: the need for a multifaceted approach
    Henry J Silverman
    Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Am J Respir Crit Care Med 169:10-4. 2004
  19. ncbi request reprint Clinical implementation of the ARDS network protocol is associated with reduced hospital mortality compared with historical controls
    Richard H Kallet
    Department of Anesthesia, University of California, San Francisco at San Francisco General Hospital, California, USA
    Crit Care Med 33:925-9. 2005
    ..To assess the impact of implementing a low tidal volume ventilation strategy on hospital mortality for patients with acute lung injury or acute respiratory distress syndrome...
  20. ncbi request reprint Palliative care in the intensive care unit: barriers, advances, and unmet needs
    Douglas B White
    Division of Pulmonary and Critical Care Medicine and Program in Medical Ethics, University of California, 521 Parnassus Avenue, Suite C 126, San Francisco, CA 94143 0903, USA
    Crit Care Clin 20:329-43, vii. 2004
    ..As ongoing research efforts yield new insights, our ability to practice evidence-based palliative care in the ICU will grow, and new avenues for improvement will become evident...
  21. ncbi request reprint Detection of patient-ventilator asynchrony during low tidal volume ventilation, using ventilator waveform graphics
    Richard H Kallet
    National Heart, Lung, and Blood Institute s ARDS Network, University of California, San Francisco General Hospital, 94110, USA
    Respir Care 47:183-5. 2002
  22. doi request reprint Medical malpractice and the chest physician
    John M Luce
    Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, San Francisco, CA 94110, USA
    Chest 134:1044-50. 2008
    ..And by stressing individual accountability, it conflicts with a systems-oriented approach to reducing medical errors...
  23. ncbi request reprint Intensive care of human immunodeficiency virus-infected patients during the era of highly active antiretroviral therapy
    Alison Morris
    Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA, USA
    Am J Respir Crit Care Med 166:262-7. 2002
    ..These patients may have an improved survival because of effects of therapy on variables such as likelihood of non-AIDS-associated admission diagnoses and serum albumin levels...
  24. ncbi request reprint Is the concept of informed consent applicable to clinical research involving critically ill patients?
    John M Luce
    San Francisco General Hospital, CA, USA
    Crit Care Med 31:S153-60. 2003
    ..Stronger research oversight may be as important as informed consent in protecting patient welfare...
  25. ncbi request reprint Three patients who asked that life support be withheld or withdrawn in the surgical intensive care unit
    John M Luce
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, USA
    Crit Care Med 30:775-80. 2002
    ..To illustrate some of the difficulties encountered in the transition from restorative to palliative care and in the pursuit of patient autonomy in the intensive care unit...
  26. pmc Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury
    Carolyn S Calfee
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143 0111, USA
    Intensive Care Med 35:248-57. 2009
    ....
  27. doi request reprint Recommendations for end-of-life care in the intensive care unit: a consensus statement by the American College [corrected] of Critical Care Medicine
    Robert D Truog
    Harvard Medical School and Children s Hospital, Boston, MA, USA
    Crit Care Med 36:953-63. 2008
    ..S. perspective. They do not use an evidence grading system because most of the recommendations are based on ethical and legal principles that are not derived from empirically based evidence...
  28. ncbi request reprint Quality indicators for end-of-life care in the intensive care unit
    Ellen B Clarke
    Center for Applied Ethics and Professional Practice, University of Washington, Seattle, USA
    Crit Care Med 31:2255-62. 2003
    ..A second goal was to propose specific clinician and organizational behaviors and interventions that might be used to improve these EOLC quality indicators...
  29. ncbi request reprint A legally sanctioned process for resolving conflicts about treatment considered medically inappropriate
    John M Luce
    Crit Care Med 35:1419-20. 2007
  30. ncbi request reprint Ethics consultation in the intensive care unit
    Douglas B White
    JAMA 290:3191; author reply 3191-2. 2003
  31. ncbi request reprint A content analysis of forms, guidelines, and other materials documenting end-of-life care in intensive care units
    Ellen B Clarke
    Department of Critical Care Medicine, Brown University, Rhode Island Hospital, Providence, RI, USA
    J Crit Care 19:108-17. 2004
    ..A second purpose was to determine how these materials might be modified to include more EOLC content and used to trigger clinical behaviors that might improve the quality of EOLC...
  32. ncbi request reprint Rationing critical care beds: a systematic review
    Tasnim Sinuff
    Crit Care Med 32:1588-97. 2004
    ..Rationing critical care beds occurs daily in the hospital setting. The objective of this systematic review was to examine the impact of rationing intensive care unit beds on the process and outcomes of care...
  33. ncbi request reprint International differences in end-of-life attitudes in the intensive care unit: results of a survey
    Arino Yaguchi
    Department of Intensive Care Medicine, Erasme Hospital, Free University of Brussels, Brussels, Belgium
    Arch Intern Med 165:1970-5. 2005
    ..Important international differences exist in attitudes toward end-of-life issues in the intensive care unit...
  34. ncbi request reprint The imperfect diagnosis of acute respiratory distress syndrome
    John M Luce
    Crit Care Med 33:2419-20. 2005
  35. pmc Reasons for nonenrollment in a clinical trial of acute lung injury
    Andrea E Glassberg
    The Permanente Medical Group, 39400 Paseo Padre Parkway, Fremont, CA 94538, USA
    Chest 134:719-23. 2008
    ..We examined the reasons for nonenrollment and the impact of the availability of a surrogate decision maker on critical care clinical trials enrollment...
  36. ncbi request reprint Acknowledging our mistakes
    John M Luce
    Crit Care Med 34:1575-6. 2006
  37. ncbi request reprint Rationing in the intensive care unit
    Robert D Truog
    Professor of Medical Ethics and Anesthesia Pediatrics, Harvard Medical School, Senior Associate in Critical Care Medicine, Children s Hospital, Boston, MA, USA
    Crit Care Med 34:958-63; quiz 971. 2006
    ..quot; Although some have maintained that rationing of health care is unethical, we argue that rationing is not only unavoidable but essential to ensuring the ethical distribution of medical goods and services...