Bingjian Lu

Summary

Publications

  1. doi request reprint Analysis of SOX9 expression in colorectal cancer
    Bingjian Lu
    Department of Pathology, School of Medicine, Zhejiang University Department of Anatomical and Cellular Pathology, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Am J Clin Pathol 130:897-904. 2008
  2. ncbi request reprint [DHPLC analysis of microsatellite instability in gastric cancer]
    Bing jian Lu
    Department of Surgical Pathology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University Hangzhou 310 016, China
    Yi Chuan 26:574-8. 2004
  3. ncbi request reprint [Germline polymorphisms of Bat26 and its significance in gastric cancer microsatellite instability]
    Bing jian Lu
    Deparment of Pathology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:353-7. 2005
  4. ncbi request reprint [Bioinformatic analysis of adenoma-normal mucosa SSH library of colon]
    Bing jian Lu
    Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University, Hangzhou 310031, China
    Yi Chuan 28:385-92. 2006
  5. pmc A transcriptome anatomy of human colorectal cancers
    Bingjian Lu
    Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University, PR, 310031, China
    BMC Cancer 6:40. 2006
  6. doi request reprint SVM-T-RFE: a novel gene selection algorithm for identifying metastasis-related genes in colorectal cancer using gene expression profiles
    Xiaobo Li
    Department of Pathology, School of Medicine, Zhejiang University, Hangzhou 310058, People s Republic of China
    Biochem Biophys Res Commun 419:148-53. 2012
  7. doi request reprint TaqMan low density array is roughly right for gene expression quantification in colorectal cancer
    Bingjian Lu
    Department of Pathology, School of Medicine, Zhejiang University, PR China
    Clin Chim Acta 389:146-51. 2008
  8. doi request reprint Downregulation of Krüppel-like factor 9 in human colorectal cancer
    Ling Kang
    Department of Pathology and Pathophysiology, Affiliated Women s Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Pathol Int 58:334-8. 2008
  9. doi request reprint Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach
    Hua Xue
    Department of Pathology and Pathophysiology, Affiliated Women s Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Proteome Res 9:545-55. 2010
  10. ncbi request reprint Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese
    Enping Xu
    Department of Pathology and Pathophysiology, Center for Environmental Genomics, School of Medicine, Zhejiang University, and Department of Clinical Pathology, Sir Run Run Shaw Hospital, Hangzhou, China
    Mol Carcinog 46:924-9. 2007

Collaborators

Detail Information

Publications26

  1. doi request reprint Analysis of SOX9 expression in colorectal cancer
    Bingjian Lu
    Department of Pathology, School of Medicine, Zhejiang University Department of Anatomical and Cellular Pathology, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Am J Clin Pathol 130:897-904. 2008
    ..05). The detection of SOX9 expression might contribute to predicting clinical outcomes for patients with colorectal cancer...
  2. ncbi request reprint [DHPLC analysis of microsatellite instability in gastric cancer]
    Bing jian Lu
    Department of Surgical Pathology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University Hangzhou 310 016, China
    Yi Chuan 26:574-8. 2004
    ..Results obtained from DHPLC and gel electrophoresis were completely consistent. Thus, DHPLC analysis of Bat26 site may be a favorable method of detecting MSI-H status in gastric cancer, and be of clinical importance...
  3. ncbi request reprint [Germline polymorphisms of Bat26 and its significance in gastric cancer microsatellite instability]
    Bing jian Lu
    Deparment of Pathology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:353-7. 2005
    ..To detect the germline polymorphic variations of Bat26 in Chinese and its significance in microsatellite instability (MSI) study of gastric cancers...
  4. ncbi request reprint [Bioinformatic analysis of adenoma-normal mucosa SSH library of colon]
    Bing jian Lu
    Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University, Hangzhou 310031, China
    Yi Chuan 28:385-92. 2006
    ..The candidate genes in A-N library would be of great significance in disclosing the molecular mechanism underlying in colonic adenoma initiation and progression...
  5. pmc A transcriptome anatomy of human colorectal cancers
    Bingjian Lu
    Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University, PR, 310031, China
    BMC Cancer 6:40. 2006
    ..A practical approach is to mine a global transcriptome profile of disease from public database. New concepts of these diseases might emerge by landscaping this profile...
  6. doi request reprint SVM-T-RFE: a novel gene selection algorithm for identifying metastasis-related genes in colorectal cancer using gene expression profiles
    Xiaobo Li
    Department of Pathology, School of Medicine, Zhejiang University, Hangzhou 310058, People s Republic of China
    Biochem Biophys Res Commun 419:148-53. 2012
    ..A fraction of selected genes have been reported to be associated with CRC development or metastasis...
  7. doi request reprint TaqMan low density array is roughly right for gene expression quantification in colorectal cancer
    Bingjian Lu
    Department of Pathology, School of Medicine, Zhejiang University, PR China
    Clin Chim Acta 389:146-51. 2008
    ..TaqMan low density array (LDA) is promising for high throughput screening in functional genomics by simultaneously measuring mRNA expression of multiple genes. However, the reproducibility and reliability remain to be explored...
  8. doi request reprint Downregulation of Krüppel-like factor 9 in human colorectal cancer
    Ling Kang
    Department of Pathology and Pathophysiology, Affiliated Women s Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Pathol Int 58:334-8. 2008
    ..001) on tissue microarray. These results indicate that KLF9 may be involved in the carcinogenesis of human colorectal cancer...
  9. doi request reprint Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach
    Hua Xue
    Department of Pathology and Pathophysiology, Affiliated Women s Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    J Proteome Res 9:545-55. 2010
    ..Both trefoil factor 3 and growth/differentiation factor 15 could serve as potential biomarkers for the prediction of colorectal cancer metastasis...
  10. ncbi request reprint Association of matrix metalloproteinase-2 and -9 promoter polymorphisms with colorectal cancer in Chinese
    Enping Xu
    Department of Pathology and Pathophysiology, Center for Environmental Genomics, School of Medicine, Zhejiang University, and Department of Clinical Pathology, Sir Run Run Shaw Hospital, Hangzhou, China
    Mol Carcinog 46:924-9. 2007
    ..Our results suggest that the presence of -1575G allele in the MMP-2 promoter region may be of significance in the assessment of colorectal cancer risk and invasive potential...
  11. doi request reprint Dynamic down-regulation of Krüppel-like factor 4 in colorectal adenoma-carcinoma sequence
    Jing Xu
    Department of Pathology, School of Medicine, Zhejiang University, Hangzhou, 310058, People s Republic of China
    J Cancer Res Clin Oncol 134:891-8. 2008
    ..To explore the clinical significance of Krüppel-like factors 4 (KLF4) expression in colorectal cancer initiation and progression...
  12. ncbi request reprint Systemic analysis of the differential gene expression profile in a colonic adenoma-normal SSH library
    Bingjian Lu
    Department of Pathology and Pathophysiology, Zhejiang University, PR China
    Clin Chim Acta 378:42-7. 2007
    ..In our previous study, we have developed an adenoma minus normal mucosa suppression subtractive hybridization (SSH) library and identified 109 differentially expressed clones...
  13. doi request reprint Tumor suppressor gene insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) induces senescence-like growth arrest in colorectal cancer cells
    Yu Ma
    Department of Pathology, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310058, China
    Exp Mol Pathol 85:141-5. 2008
    ..Restoration of IGFBP-rP1 function might have potential therapeutic significance in colorectal cancer...
  14. ncbi request reprint Differential expression of mimecan and thioredoxin domain-containing protein 5 in colorectal adenoma and cancer: a proteomic study
    YingHong Wang
    Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University, Hangzhou, 310058, China
    Exp Biol Med (Maywood) 232:1152-9. 2007
    ..Thus, the differentially expressed proteins might serve as potential biomarkers for colorectal cancer detection and intervention...
  15. doi request reprint -8p12-23 and +20q are predictors of subtypes and metastatic pathways in colorectal cancer: construction of tree models using comparative genomic hybridization data
    Xiaobo Li
    Department of Pathology, School of Medicine, Zhejiang University, Hangzhou 310058, People s Republic of China
    OMICS 15:37-47. 2011
    ..Particularly, the metastatic pathways we describe may provide pivotal clues for metastatic candidate genes, and thus impact on the prediction and intervention of metastatic colorectal cancer...
  16. doi request reprint Serum insulin-like, growth factor binding protein-related protein 1 (IGFBP-rP1) and endometrial cancer risk in Chinese women
    Yan Zhan
    Department of Clinical Laboratory, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, China
    Int J Cancer 132:411-6. 2013
    ..13; 95% CI = 1.30-3.49; IGFBP-rP1: 0.57; 95% CI = 0.34-0.94). Hyperinsulinemia and high IGFBP-rP1 levels confer altered risks for endometrial carcinoma...
  17. ncbi request reprint Expression of REG4 in ovarian mucinous tumors
    Qiong Huang
    Departments of Pathology and Pathophysiology Surgical Pathology Gynecologic Oncology, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, Zhejiang Province, P R China
    Appl Immunohistochem Mol Morphol 22:295-301. 2014
    ..Expression of CK7/REG4 may contribute to the differential diagnosis between primary and metastatic ovarian mucinous tumors. ..
  18. doi request reprint The association between metabolic abnormality and endometrial cancer: a large case-control study in China
    Yan Zhang
    Department of Clinical Pathology, Affiliated Women s Hospital, School of Medicine, Zhejiang University, PR China
    Gynecol Oncol 117:41-6. 2010
    ..To investigate the association between insulin-resistance-related conditions (comprising the metabolic syndrome) and endometrial cancer risk in Chinese women...
  19. pmc The cancer secretome: a reservoir of biomarkers
    Hua Xue
    Department of Pathology, School of Medicine, Zhejiang University, PR China
    J Transl Med 6:52. 2008
    ..Further improvements on strategies and technologies will continue to drive forward cancer secretome research and enable development of a wealth of clinically valuable cancer biomarkers...
  20. ncbi request reprint Secretagogin, a novel neuroendocrine marker, has a distinct expression pattern from chromogranin A
    Maode Lai
    Department of Pathology and Pathophysiology, School of Medicine, Zhejiang University, and Department of Surgical Pathology, The First Affiliated Hospital, Zhejiang, China
    Virchows Arch 449:402-9. 2006
    ..We conclude that SCGN is a novel neuroendocrine marker that may be useful in routine surgical pathology practice...
  21. ncbi request reprint No association between the polymorphisms in matrix metalloproteinase-1 and matrix metalloproteinase-3 promoter regions and colorectal cancer in Chinese
    Enping Xu
    Department of Pathology and Pathophysiology, Center for Environmental Genomics, School of Medicine, Zhejiang University, Hangzhou 310031, China
    Dis Colon Rectum 49:1439-44. 2006
    ..In this study, we investigated whether these functional polymorphisms are associated with colorectal cancer in a Chinese population...
  22. doi request reprint Epithelioid trophoblastic tumor: an outcome-based literature review of 78 reported cases
    Xiaofei Zhang
    Department of Surgical Pathology, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, China
    Int J Gynecol Cancer 23:1334-8. 2013
    ..This analysis aimed to assess the effects of current management on clinical outcomes and to identify potential prognostic indicators in ETT...
  23. doi request reprint Microwave heating of long-term formalin-fixed surgical pathology specimens improves quality of extracted DNA
    Shanshui Wu
    Department of Oncology, Quzhou Municipal Hospital, Quzhou, Zhejiang Province, PR China
    Appl Immunohistochem Mol Morphol 20:512-7. 2012
    ..The successful fluorescence multiplex polymerase chain reaction-capillary electrophoresis analysis in these samples might facilitate MSI detection in clinical practice...
  24. doi request reprint Atypical epithelioid trophoblastic lesion with cyst and fistula formation after a cesarean section: a rare form of gestational trophoblastic disease
    Yun Liang
    Department of Surgical Pathology, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, Zhejiang, P R China
    Int J Gynecol Pathol 31:458-62. 2012
    ..The Ki67 indexes were 12.7% and 8.6%, respectively. We propose their description as atypical epithelioid trophoblastic lesions with cyst and fistula formation after a Cesarean section...
  25. ncbi request reprint Ovarian steroid cell tumor, not otherwise specified (NOS): an unusual case with myelolipoma
    Xiaofei Zhang
    Department of Surgical Pathology, Women s Reproductive Health Laboratory of Zhejiang Province, the Affiliated Women s Hospital, School of Medicine, Zhejiang University, 2 Xueshi Road, Hangzhou, Zhejiang, China
    Int J Gynecol Pathol 30:460-5. 2011
    ..Lineage-specific markers including myeloid peroxidase were variably expressed in hematopoietic cells. This rare case will expand our appreciation of the spectrum and histogenesis of ovarian tumors...
  26. pmc The expressions of bHLH gene HES1 and HES5 in advanced ovarian serous adenocarcinomas and their prognostic significance: a retrospective clinical study
    Xinyu Wang
    Women s Reproductive Health Laboratory of Zhejiang Province, Department of Gynecologic Oncology, Women s Hospital, School of Medicine, Zhejiang University, 310006 Hangzhou, China
    J Cancer Res Clin Oncol 136:989-96. 2010
    ..The aim of the study is to investigate significance of the expression of HES1/HES5 protein, downstream effectors of Notch, in prognosis of the patients with advanced ovarian epithelial cancers...