Francisco López-Muñoz

Summary

Publications

  1. ncbi request reprint [The historical background of the pineal gland: II. From the seat of the soul to a neuroendocrine organ]
    Francisco López-Muñoz
    Universidad de Alcala Facultad de Medicina, Alcala de Henares, Espana
    Rev Neurol 50:117-25. 2010
  2. ncbi request reprint [The historical background of the pineal gland: I. From a spiritual valve to the seat of the soul]
    Francisco López-Muñoz
    Departamento de Farmacologia, Universidad de Alcala, Facultad de Medicina, Alcala de Henares, Espana
    Rev Neurol 50:50-7. 2010
  3. ncbi request reprint A bibliometric study of scientific research conducted on second-generation antipsychotic drugs in Singapore
    Francisco López-Muñoz
    Faculty of Health Sciences, Camilo José Cela University, C Castillo de Alarcón, 49, Urb Villafranca del Castillo, Villanueva de la Canada, 28692 Madrid, Spain
    Singapore Med J 55:24-33. 2014
  4. doi request reprint The Australian contribution to the literature on atypical antipsychotic drugs: a bibliometric study
    Francisco López-Muñoz
    Faculty of Health Sciences, and Director of International Doctoral School, Camilo José Cela University, Madrid, Spain
    Australas Psychiatry 21:343-5. 2013
  5. doi request reprint [The pineal gland as physical tool of the soul faculties: a persistent historical connection]
    F Lopez-Munoz
    Departamento de Farmacologia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Neurologia 27:161-8. 2012
  6. ncbi request reprint The role of serendipity in the discovery of the clinical effects of psychotropic drugs: beyond of the myth
    Francisco López-Muñoz
    Pharmacology Department, Universidad Camilo Jose Cela, Madrid, Spain
    Actas Esp Psiquiatr 40:34-42. 2012
  7. doi request reprint The discovery of chlordiazepoxide and the clinical introduction of benzodiazepines: half a century of anxiolytic drugs
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Anxiety Disord 25:554-62. 2011
  8. doi request reprint Sadness as a passion of the soul: a psychopathological consideration of the Cartesian concept of melancholy
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Ctra Madrid Barcelona, Km 33, 600, Alcalá de Henares 29971, Madrid, Spain
    Brain Res Bull 85:42-53. 2011
  9. doi request reprint Neurobiological background for the development of new drugs in schizophrenia
    Francisco López-Muñoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    Clin Neuropharmacol 34:111-26. 2011
  10. doi request reprint An historical view of the pineal gland and mental disorders
    F Lopez-Munoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Clin Neurosci 18:1028-37. 2011

Collaborators

Detail Information

Publications39

  1. ncbi request reprint [The historical background of the pineal gland: II. From the seat of the soul to a neuroendocrine organ]
    Francisco López-Muñoz
    Universidad de Alcala Facultad de Medicina, Alcala de Henares, Espana
    Rev Neurol 50:117-25. 2010
    ..Throughout history a number of speculations have been put forward concerning the functional role of the pineal gland, perhaps some of the most important being the neurophysiological proposals by Descartes...
  2. ncbi request reprint [The historical background of the pineal gland: I. From a spiritual valve to the seat of the soul]
    Francisco López-Muñoz
    Departamento de Farmacologia, Universidad de Alcala, Facultad de Medicina, Alcala de Henares, Espana
    Rev Neurol 50:50-7. 2010
    ..Throughout history, the special anatomical location of the pineal gland in the central nervous system has given rise to a number of physiological hypotheses regarding the functional role of this organ...
  3. ncbi request reprint A bibliometric study of scientific research conducted on second-generation antipsychotic drugs in Singapore
    Francisco López-Muñoz
    Faculty of Health Sciences, Camilo José Cela University, C Castillo de Alarcón, 49, Urb Villafranca del Castillo, Villanueva de la Canada, 28692 Madrid, Spain
    Singapore Med J 55:24-33. 2014
    ..A bibliometric study was carried out to ascertain the volume and impact of scientific literature published on second-generation antipsychotic drugs (SGAs) in Singapore from 1997 to 2011...
  4. doi request reprint The Australian contribution to the literature on atypical antipsychotic drugs: a bibliometric study
    Francisco López-Muñoz
    Faculty of Health Sciences, and Director of International Doctoral School, Camilo José Cela University, Madrid, Spain
    Australas Psychiatry 21:343-5. 2013
    ..We performed a bibliometric study on scientific publications on atypical antipsychotic drugs (AADs) from Australia...
  5. doi request reprint [The pineal gland as physical tool of the soul faculties: a persistent historical connection]
    F Lopez-Munoz
    Departamento de Farmacologia, Facultad de Medicina, Universidad de Alcala, Madrid, Espana
    Neurologia 27:161-8. 2012
    ..One of more known hypotheses on this subject was proposed by Descartes, for whom the soul would host in the pineal gland, a brain body with a special location that would adequately address the functionalism of the human body...
  6. ncbi request reprint The role of serendipity in the discovery of the clinical effects of psychotropic drugs: beyond of the myth
    Francisco López-Muñoz
    Pharmacology Department, Universidad Camilo Jose Cela, Madrid, Spain
    Actas Esp Psiquiatr 40:34-42. 2012
    ..This is the case of imipramine, lithium salts, chlorpromazine or meprobamate...
  7. doi request reprint The discovery of chlordiazepoxide and the clinical introduction of benzodiazepines: half a century of anxiolytic drugs
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Anxiety Disord 25:554-62. 2011
    ....
  8. doi request reprint Sadness as a passion of the soul: a psychopathological consideration of the Cartesian concept of melancholy
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Ctra Madrid Barcelona, Km 33, 600, Alcalá de Henares 29971, Madrid, Spain
    Brain Res Bull 85:42-53. 2011
    ..From the 19th century onwards, emotional symptomatology finally began to be used in diagnostic criteria for mood disorders...
  9. doi request reprint Neurobiological background for the development of new drugs in schizophrenia
    Francisco López-Muñoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    Clin Neuropharmacol 34:111-26. 2011
    ....
  10. doi request reprint An historical view of the pineal gland and mental disorders
    F Lopez-Munoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Clin Neurosci 18:1028-37. 2011
    ....
  11. ncbi request reprint Bibliometric analysis of biomedical publications on SSRI during 1980-2000
    Francisco López-Muñoz
    Department of Pharmacology, University of Alcala, Madrid, Spain
    Depress Anxiety 18:95-103. 2003
    ....
  12. ncbi request reprint Reboxetine adjunct for partial or nonresponders to antidepressant treatment
    Gabriel Rubio
    Psychiatry Service, La Paz University Hospital, Madrid, Spain
    J Affect Disord 81:67-72. 2004
    ..To investigate the usefulness of the combination therapy with two antidepressants from different pharmacological families in treatment-resistant depressive patients...
  13. ncbi request reprint Neuron theory, the cornerstone of neuroscience, on the centenary of the Nobel Prize award to Santiago Ramón y Cajal
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, C Juan Ignacio Luca de Tena 8, 28027 Madrid, Spain
    Brain Res Bull 70:391-405. 2006
    ..Today, no neuroscientific discipline could be understood without recourse to the concept of neuronal individuality and nervous transmission at a synaptic level, as basic units of the nervous system...
  14. ncbi request reprint Mapping the scientific research on atypical antipsychotic drugs in Spain: a bibliometric assessment
    Francisco López-Muñoz
    Faculty of Health Sciences, Camilo José Cela University Madrid, Spain Department of Pharmacology, University of Alcala Madrid, Spain Hospital 12 de Octubre Research Institute Madrid, Spain
    Actas Esp Psiquiatr 41:349-60. 2013
    ..We carried out a bibliometric study on the scientific publications in relation to atypical antipsychotic drugs (AADs) in Spain...
  15. ncbi request reprint History of the discovery and clinical introduction of chlorpromazine
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    Ann Clin Psychiatry 17:113-35. 2005
    ..The historical process of discovery and clinical introduction of chlorpromazine, one of the greatest advances of 20th century medicine and history of psychiatry, is analyzed...
  16. ncbi request reprint Adjunctive treatment with risperidone in clozapine-resistant schizophrenia: a case report and review
    Ivan Lerma-Carrillo
    Acute Inpatients Unit, Dr R Lafora Psychiatric Hospital, Madrid, Spain
    Clin Neuropharmacol 30:114-21. 2007
    ..The combination of clozapine and risperidone in the treatment of partial responders to clozapine has been one of those receiving most interest from research...
  17. ncbi request reprint Half a century of antidepressant drugs: on the clinical introduction of monoamine oxidase inhibitors, tricyclics, and tetracyclics. Part I: monoamine oxidase inhibitors
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Clin Psychopharmacol 27:555-9. 2007
  18. ncbi request reprint "Than all the herbs described by Dioscorides...": the traces of Andrés Laguna in the works of Cervantes
    Francisco López-Muñoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    Pharm Hist 49:87-108. 2007
  19. ncbi request reprint Psychiatry and political-institutional abuse from the historical perspective: the ethical lessons of the Nuremberg Trial on their 60th anniversary
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Pharmacology Department, University of Alcala, Madrid, Spain
    Prog Neuropsychopharmacol Biol Psychiatry 31:791-806. 2007
    ..Various strategies can be used to combat such abuses, though it is uncertain how effective they are in preventing them...
  20. doi request reprint Historical evolution of the neurotransmission concept
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, University of Alcala, Madrid, Spain
    J Neural Transm 116:515-33. 2009
    ..Finally, we describe the process of the discovery of the different neurotransmitters and neuroreceptors, and analyse the new interpretations postulated in relation to the neurotransmission concept at the dawn of the twenty-first century...
  21. ncbi request reprint Evolution of Spanish scientific production in international obstetrics and gynecology journals during the period 1986-2002
    Pilar García-García
    Pharmacology Department, University of Alcala, Madrid, Spain
    Eur J Obstet Gynecol Reprod Biol 123:150-6. 2005
    ..The present bibliometric study analyzes Spanish scientific work published in the field of obstetrics and gynecology in the most important journals during the period 1986-2002...
  22. pmc Psychotropic drugs in the Cervantine texts
    Francisco López-Muñoz
    Department of Pharmacology, Neuropsychopharmacology Unit, University of Alcala, Madrid, Spain
    J R Soc Med 101:226-34. 2008
  23. ncbi request reprint Reboxetine addition in patients with mirtazapine-resistant depression: a case series
    Francisco López-Muñoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    Clin Neuropharmacol 29:192-6. 2006
    ....
  24. doi request reprint The role of psychopharmacology in the medical abuses of the Third Reich: from euthanasia programmes to human experimentation
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Campus Universitario, Ctra Madrid Barcelona Km 33, 600, 28871 Alcala de Henares, Madrid, Spain
    Brain Res Bull 77:388-403. 2008
    ....
  25. doi request reprint The consolidation of neuroleptic therapy: Janssen, the discovery of haloperidol and its introduction into clinical practice
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Ctra Madrid Barcelona, Km 33600, Alcala de Henares, 29971 Madrid, Spain
    Brain Res Bull 79:130-41. 2009
    ..Haloperidol has been included in the World Health Organisation's list of essential medicines...
  26. doi request reprint Reboxetine for ADHD in children non-responders or with poor tolerance to methylphenidate: a prospective long-term open-label study
    Javier Quintero
    Department of Psychiatry, Infanta Leonor Hospital, Madrid, Spain
    Atten Defic Hyperact Disord 2:107-13. 2010
    ..The initial findings of our study show that reboxetine may constitute an effective tool for long-term treatment of children with ADHD who present poor response or poor tolerance to initial treatment with methylphenidate...
  27. ncbi request reprint Effects of lamotrigine in patients with bipolar disorder and alcohol dependence
    Gabriel Rubio
    Retiro Health Mental Services, Madrid, Spain
    Bipolar Disord 8:289-93. 2006
    ..Open-label lamotrigine was examined in 28 outpatients with DSM-IV bipolar disorder and alcohol dependence. Lamotrigine was added to existing medication regimens...
  28. ncbi request reprint Bipolar disorder as an emerging pathology in the scientific literature: a bibliometric approach
    Francisco López-Muñoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    J Affect Disord 92:161-70. 2006
    ..To carry out a bibliometric study on the scientific publications in relation to bipolar disorder...
  29. ncbi request reprint Psychopathology in the Lujan-Fryns syndrome: report of two patients and review
    Ivan Lerma-Carrillo
    Acute Inpatients Unit, Dr R Lafora Psychiatric Hospital, Madrid, Spain
    Am J Med Genet A 140:2807-11. 2006
    ..Additionally, the high prevalence of psychopathological alterations in these patients suggests the need for psychiatric evaluation at the time of diagnosis...
  30. ncbi request reprint Long-acting injectable risperidone compared with zuclopenthixol in the treatment of schizophrenia with substance abuse comorbidity
    Gabriel Rubio
    Department of Psychiatry, Complutense University, Madrid, Spain
    Can J Psychiatry 51:531-9. 2006
    ..This study aimed to compare the efficacy of long-acting risperidone and zuclopenthixol in subjects with schizophrenia and substance abuse...
  31. ncbi request reprint The neurobiological interpretation of the mental functions in the work of Santiago Ramón y Cajal
    Francisco López-Muñoz
    University of Alcala, Madrid
    Hist Psychiatry 19:5-24. 2008
    ..After being awarded the Nobel Prize in 1906, Cajal's interests in psychological aspects began to decline...
  32. doi request reprint A bibliometric study of international scientific productivity in attention-deficit hyperactivity disorder covering the period 1980-2005
    Francisco López-Muñoz
    Dept of Pharmacology, Faculty of Medicine, University of Alcala, C Juan Ignacio Luca de Tena 8, 28027 Madrid, Spain
    Eur Child Adolesc Psychiatry 17:381-91. 2008
    ..We have carried out a bibliometric analysis of scientific publications related to attention-deficit hyperactivity disorder (ADHD) and its pharmacological treatment over the period 1980-2005...
  33. ncbi request reprint Management of depression in primary care: a survey of general practitioners in Spain
    Belén Martín-Agueda
    Pharmacology Department, University of Alcala, C Juan Ignacio Luca de Tena 8, 28027 Madrid, Spain
    Gen Hosp Psychiatry 27:305-12. 2005
    ....
  34. ncbi request reprint "The herbs that have the property of healing...,": the phytotherapy in Don Quixote
    Francisco López-Muñoz
    Department of Pharmacology, Faculty of Medicine, University of Alcala, C Juan Ignacio Luca de Tena 8, 28027 Madrid, Spain
    J Ethnopharmacol 106:429-41. 2006
    ..Also, we have examined the possible scientific influences, which might have inspired Cervantes in this field, mainly the work of Andrés Laguna (Dioscorides' Materia Medica)...
  35. doi request reprint Combined treatment with amisulpride in patients with schizophrenia discharged from a short-term hospitalization unit: a 1-year retrospective study
    Juan D Molina
    Doctor R Lafora Psychiatric Hospital, Madrid, Spain
    Clin Neuropharmacol 32:10-5. 2009
    ..The objective of this study is to describe polypharmacy with antipsychotic regimen in patients with schizophrenia discharged with amisulpride from the short-term hospitalization unit...
  36. ncbi request reprint Monoaminergic neurotransmission: the history of the discovery of antidepressants from 1950s until today
    Francisco López-Muñoz
    Neuropsychopharmacology Unit, Department of Pharmacology, Faculty of Medicine, University of Alcala, Madrid, Spain
    Curr Pharm Des 15:1563-86. 2009
    ....
  37. ncbi request reprint The effectiveness of lurasidone as an adjunct to lithium or divalproex in the treatment of bipolar disorder
    Cecilio Alamo
    Department of Biomedical Sciences Pharmacology Area, Faculty of Medicine and Health Sciences, University of Alcala, Madrid, Spain
    Expert Rev Neurother 14:593-605. 2014
    ..Additional studies are desirable to know the clinical profile of lurasidone in long-term treatment, in patients with bipolar II disorders, and versus other antipsychotic agents...