Genomes and Genes


Keat Wei Loo



  1. Wei K, Sutherland H, Camilleri E, Haupt L, Griffiths L, Gan S. Computational epigenetic profiling of CpG islets in MTHFR. Mol Biol Rep. 2014;41:8285-92 pubmed publisher
    ..These results have significant implications for the understanding of the architecture of transcription factor binding at CpG islets as well as DNA methylation patterns that affect chromatin structure. ..
  2. Wei L, Au A, Menon S, Gan S, Griffiths L. Clinical Relevance of MTHFR, eNOS, ACE, and ApoE Gene Polymorphisms and Serum Vitamin Profile among Malay Patients with Ischemic Stroke. J Stroke Cerebrovasc Dis. 2015;24:2017-25 pubmed publisher
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    Lye H, Lee Y, Ooi S, Teh L, Lim L, Wei L. Modifying progression of aging and reducing the risk of neurodegenerative diseases by probiotics and synbiotics. Front Biosci (Elite Ed). 2018;10:344-351 pubmed
  4. Wei L, Au A, Teh L, Lye H. Recent Advances in the Genetics of Hypertension. Adv Exp Med Biol. 2017;956:561-581 pubmed publisher
    ..Current review concluded the potential biomarkers for hypertension, with regards to electrolyte and fluid transports, as well as sodium/potassium ions homeostasis, which are supported by the results of case-controls and meta-analyses. ..
  5. Wei L, Au A, Menon S, Griffiths L, Kooi C, Irene L, et al. Polymorphisms of MTHFR, eNOS, ACE, AGT, ApoE, PON1, PDE4D, and Ischemic Stroke: Meta-Analysis. J Stroke Cerebrovasc Dis. 2017;26:2482-2493 pubmed publisher
  6. Au A, Griffiths L, Irene L, Kooi C, Wei L. The impact of APOA5, APOB, APOC3 and ABCA1 gene polymorphisms on ischemic stroke: Evidence from a meta-analysis. Atherosclerosis. 2017;265:60-70 pubmed publisher
    ..The present meta-analysis confirmed a significant association of APOA5 rs662799 CC, APOA5 rs3135506 CG, APOB rs1801701 GA, APOB rs1042031 GA and ABCA1 rs2230806 GG with increased risk of ischemic stroke. ..