Andreas W Loepke

Summary

Publications

  1. doi request reprint Developmental neurotoxicity of sedatives and anesthetics: a concern for neonatal and pediatric critical care medicine?
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Crit Care Med 11:217-26. 2010
  2. doi request reprint Cell age-specific vulnerability of neurons to anesthetic toxicity
    Rylon D Hofacer
    Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Ann Neurol 73:695-704. 2013
  3. doi request reprint Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex
    George K Istaphanous
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Anesth Analg 116:845-54. 2013
  4. doi request reprint Anesthetics and sedatives: toxic or protective for the developing brain?
    Christopher G Ward
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Pharmacol Res 65:271-4. 2012

Collaborators

  • John J McAuliffe
  • Christopher G Ward
  • Steve C Danzer
  • Rylon D Hofacer
  • George K Istaphanous
  • Elizabeth A Hughes
  • Bernadin Joseph
  • John C McCann
  • Connie Jiang
  • Xinyu Nan
  • Meng Deng

Detail Information

Publications4

  1. doi request reprint Developmental neurotoxicity of sedatives and anesthetics: a concern for neonatal and pediatric critical care medicine?
    Andreas W Loepke
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Pediatr Crit Care Med 11:217-26. 2010
    ..To evaluate the currently available evidence for the deleterious effects of sedatives and anesthetics on developing brain structure and neurocognitive function...
  2. doi request reprint Cell age-specific vulnerability of neurons to anesthetic toxicity
    Rylon D Hofacer
    Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Ann Neurol 73:695-704. 2013
    ..Elucidating these questions is critical for assessing the phenomenon's applicability to humans, defining the susceptible age, predicting vulnerable neuronal populations, and devising mitigating strategies...
  3. doi request reprint Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex
    George K Istaphanous
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Anesth Analg 116:845-54. 2013
    ..We conducted the present study to immunohistochemically identify the dying cells and to quantify the fraction of cells undergoing apoptotic death in neonatal mouse cortex, a substantially affected brain region...
  4. doi request reprint Anesthetics and sedatives: toxic or protective for the developing brain?
    Christopher G Ward
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
    Pharmacol Res 65:271-4. 2012
    ..The mechanisms and human applicability of anesthetic neurotoxicity and neuroprotection remain under intense investigation and this Perspectives article summarizes the current state of research...