Pierre Michel Llorca

Summary

Publications

  1. pmc Effectiveness of clozapine in neuroleptic-resistant schizophrenia: clinical response and plasma concentrations
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, BP 69, 63003 Clermont Ferrand, France
    J Psychiatry Neurosci 27:30-7. 2002
  2. ncbi request reprint Tardive dyskinesias and antipsychotics: a review
    Pierre Michel Llorca
    C M P B, C H U Clermont Ferrand, rue Montalembert, BP 69, 63003 cedex 1, Clermont Ferrand, France
    Eur Psychiatry 17:129-38. 2002
  3. doi request reprint Clinical predictors of response to olanzapine or risperidone during acute episode of schizophrenia
    Georges Brousse
    University Clermont 1, UFR Medecine, EA 3845, CHU Clermont Ferrand, Service de Psychiatrie B, Clermont Ferrand, F63001, France
    Psychiatry Res 179:12-8. 2010
  4. ncbi request reprint Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease
    Stephanie Bannier
    CHU Clermont Ferrand, Neurology Department, Clermont Ferrand, France
    J Neurol Neurosurg Psychiatry 83:1019-21. 2012
  5. ncbi request reprint Multicenter validation study of the %CDT TIA kit in alcohol abuse and alcohol dependence
    Raymund Schwan
    Department of Psychiatry, University Hospital, Clermont Ferrand, France
    Alcohol Clin Exp Res 28:1331-7. 2004
  6. doi request reprint Clinicians' attitudes toward the use of long-acting injectable antipsychotics
    Ludovic Samalin
    Department of Psychiatry B, University of Auvergne, Clermont Ferrand, France
    J Nerv Ment Dis 201:553-9. 2013
  7. doi request reprint Body weight gain and deep brain stimulation
    Isabelle Rieu
    CHU Clermont Ferrand, Neurology Department, Clermont Ferrand, F 63001, France
    J Neurol Sci 310:267-70. 2011
  8. doi request reprint Pharmacogenetic of response efficacy to antipsychotics in schizophrenia: pharmacodynamic aspects. Review and implications for clinical research
    Olivier Blanc
    Univ Clermont, UFR Medecine, Clermont Ferrand, France
    Fundam Clin Pharmacol 24:139-60. 2010
  9. ncbi request reprint A composite scale applied to evaluate anxiety in schizophrenic patients (SAES)
    Pierre Michel Llorca
    CHU of Clermont Ferrand, Psychiatry Service, Place Henri Dunant, 63000, Clermont Ferrand, France
    Eur Arch Psychiatry Clin Neurosci 264:171-8. 2014
  10. ncbi request reprint General practitioners and alcohol use disorders: quantity without quality
    Laurent Malet
    Department of Psychiatry, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Alcohol Clin Exp Res 27:61-6. 2003

Collaborators

Detail Information

Publications29

  1. pmc Effectiveness of clozapine in neuroleptic-resistant schizophrenia: clinical response and plasma concentrations
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, BP 69, 63003 Clermont Ferrand, France
    J Psychiatry Neurosci 27:30-7. 2002
    ....
  2. ncbi request reprint Tardive dyskinesias and antipsychotics: a review
    Pierre Michel Llorca
    C M P B, C H U Clermont Ferrand, rue Montalembert, BP 69, 63003 cedex 1, Clermont Ferrand, France
    Eur Psychiatry 17:129-38. 2002
    ..They are doubtlessly promising, but we cannot ignore the notion of risk-benefit; regular monitoring and listening to the subjective experience of the patients must remain uppermost in the choice of therapy...
  3. doi request reprint Clinical predictors of response to olanzapine or risperidone during acute episode of schizophrenia
    Georges Brousse
    University Clermont 1, UFR Medecine, EA 3845, CHU Clermont Ferrand, Service de Psychiatrie B, Clermont Ferrand, F63001, France
    Psychiatry Res 179:12-8. 2010
    ..Clinical variables do not clearly appear to be good predictors of treatment efficacy...
  4. ncbi request reprint Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease
    Stephanie Bannier
    CHU Clermont Ferrand, Neurology Department, Clermont Ferrand, France
    J Neurol Neurosurg Psychiatry 83:1019-21. 2012
    ..Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (OHs)...
  5. ncbi request reprint Multicenter validation study of the %CDT TIA kit in alcohol abuse and alcohol dependence
    Raymund Schwan
    Department of Psychiatry, University Hospital, Clermont Ferrand, France
    Alcohol Clin Exp Res 28:1331-7. 2004
    ..The aim of this study was to evaluate, in terms of sensitivity and specificity, the performance of the new Bio-Rad %CDT TIA kit and GGT assay for identifying alcohol abuse and alcohol dependence (according to the DSM-IV criteria)...
  6. doi request reprint Clinicians' attitudes toward the use of long-acting injectable antipsychotics
    Ludovic Samalin
    Department of Psychiatry B, University of Auvergne, Clermont Ferrand, France
    J Nerv Ment Dis 201:553-9. 2013
    ..Conversely, some attitudes related to organizational aspects, particularly the relevance of health care costs, may vary from one country to another. ..
  7. doi request reprint Body weight gain and deep brain stimulation
    Isabelle Rieu
    CHU Clermont Ferrand, Neurology Department, Clermont Ferrand, F 63001, France
    J Neurol Sci 310:267-70. 2011
    ..This review reports current knowledge concerning weight changes in patients treated by DBS with different surgical targets. It also describes the mechanisms responsible for weight gain and the health outcome for the patients...
  8. doi request reprint Pharmacogenetic of response efficacy to antipsychotics in schizophrenia: pharmacodynamic aspects. Review and implications for clinical research
    Olivier Blanc
    Univ Clermont, UFR Medecine, Clermont Ferrand, France
    Fundam Clin Pharmacol 24:139-60. 2010
    ....
  9. ncbi request reprint A composite scale applied to evaluate anxiety in schizophrenic patients (SAES)
    Pierre Michel Llorca
    CHU of Clermont Ferrand, Psychiatry Service, Place Henri Dunant, 63000, Clermont Ferrand, France
    Eur Arch Psychiatry Clin Neurosci 264:171-8. 2014
    ..The SAES can be useful to investigate clinical, psychopathological, and therapeutic aspects of anxiety in schizophrenia. ..
  10. ncbi request reprint General practitioners and alcohol use disorders: quantity without quality
    Laurent Malet
    Department of Psychiatry, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Alcohol Clin Exp Res 27:61-6. 2003
    ..General medical practitioners are essential for the prevention, diagnosis, and management of alcohol use disorders. Studies to examine medical practice in this field, however, are very rare...
  11. ncbi request reprint [Disulfiram and addiction: reminders and new perspectives of use]
    Thomas Charpeaud
    Service de Psychiatrie de l Adulte B, CHU de Clermont Ferrand, Clermont Ferrand, France
    Therapie 66:273-80. 2011
    ..Although current data are insufficient to generalize its use in routine practice, they constitute a line of research interest for the future...
  12. ncbi request reprint Performance of asialotransferrin in detecting alcohol abuse
    Raymund Schwan
    Department of Psychiatry, University Hospital, Clermont Ferrand, France
    Alcohol Clin Exp Res 29:81-3. 2005
    ..The present study evaluated the performance of asialotransferrin, a newly proposed biomarker for alcohol use disorders, in detecting alcohol abuse and alcohol dependence...
  13. ncbi request reprint Alcohol consumption during pregnancy: a urge to increase prevention and screening
    Laurent Malet
    Psychiatrie B, CHU Clermont Ferrand, Rue Montalembert BP 69, F 63000, Clermont Ferrand, France
    Eur J Epidemiol 21:787-8. 2006
    ..One percent had 5 or more units per occasion. Despite the consensus recommending total abstinence during pregnancy, prenatal alcohol exposure remains a major public health issue...
  14. doi request reprint [Mixed states]
    Pierre Michel Llorca
    CHU Clermont Ferrand, BP 69, Clermont Ferrand cedex 01, France
    Encephale 38:S179-85. 2012
    ..As the evolution, the prognosis or the therapeutic strategies differ from what is applied in other thymic episodes, this transition from "mixed state" to manic or depressive episodes "with mixed features" may be relevant in practice...
  15. doi request reprint Hypersexuality and pathological gambling in Parkinson's disease: A cross-sectional case-control study
    Ingrid de Chazeron
    Univ Clermont 1, UFR Medecine, Clermont Ferrand, France
    Mov Disord 26:2127-30. 2011
    ....
  16. pmc Treatment in hospital for alcohol-dependent patients decreases attentional bias
    Valentin Flaudias
    Clermont Universite, EA 7280 NPsy Sydo, Clermont Ferrand, France Pôle Psychiatrie B, CHU Gabriel Montpied, Clermont Ferrand, France
    Neuropsychiatr Dis Treat 9:773-9. 2013
    ..The goal of the current study was to examine modification of AB during specialized hospitalization for alcohol dependence, with the suppression of a training bias that could be present in within-subject design...
  17. pmc Guidelines for the use and management of long-acting injectable antipsychotics in serious mental illness
    Pierre Michel Llorca
    CHU Clermont Ferrand, EA 7280, Clermont Ferrand University, Clermont Ferrand, France
    BMC Psychiatry 13:340. 2013
    ..As part of a process to improve the quality of care, the French Association for Biological Psychiatry and Neuropsychopharmacology (AFPBN) elaborated guidelines for the use and management of antipsychotic depots in clinical practice...
  18. doi request reprint Second meeting of the French CEIP (Centres d'Evaluation et d'Information sur la Pharmacodépendance). Part II: benzodiazepine withdrawal
    Nicolas Authier
    CEIP associé, Service de Pharmacologie, CHU Clermont Ferrand, Clermont Ferrand, France
    Therapie 64:365-70. 2009
    ..However more controlled clinical trials are needed to promote adequate and optimal patient care in management of benzodiazepine withdrawing...
  19. ncbi request reprint Tardive dyskinesia and glucid metabolism
    Georges Brousse
    CHU Clermont Ferrand, Service de Psychiatrie B, rue Montalembert, France
    Hum Psychopharmacol 22:373-80. 2007
    ..A role of insulin-dependent diabetes in the onset of tardive dyskinesia has been reported and relies on weak physiopathological evidence...
  20. ncbi request reprint Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study
    Pierre Michel Llorca
    Hopital Gabriel Montpied, Clermont Ferrand, France
    J Clin Psychiatry 63:1020-7. 2002
    ..The aim of the current study was to confirm those positive results over a 3-month period in adult outpatients...
  21. ncbi request reprint The use of biological laboratory markers in the diagnosis of alcohol misuse: an evidence-based approach
    Raymund Schwan
    Department of Psychiatry, University Medical School, Clermont Ferrand, France
    Drug Alcohol Depend 74:273-9. 2004
    ..Our aim was to determine how best to use biological markers to objectify alcohol problems in patients with clinical suspicion of alcohol misuse...
  22. pmc Asenapine in bipolar I disorder: evidence and place in patient management
    Ludovic Samalin
    centre hospitalier universitaire de Clermont Ferrand, Psychiatry B, 58, rue Montalembert, Clermont Ferrand 63000, France
    Ther Adv Chronic Dis 4:5-14. 2013
    ..This tolerability profile confirms the heterogeneity of the second-generation antipsychotic class and supports the view of some authors for the need to re-evaluate the boundaries of this group...
  23. ncbi request reprint Discussion of prevalence and management of discomfort when swallowing pills: orodispersible tablets expand treatment options in patients with depression
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, BP 69, 63003, Clermont Ferrand, Cedex I, France
    Ther Deliv 2:611-22. 2011
    ..Orodispersible tablets do not need to be taken with water and can be packaged discreetly in single doses. Orodispersible tablets have been shown to be effective in a number of therapy areas including depression...
  24. ncbi request reprint Limits of usual biochemical alcohol markers in cord blood at term: a fetal/maternal population-based study
    Denis Gallot
    Universite d Auvergne, JE2447, ARDEMO, and CHU, maternité Hôtel Dieu, Clermont Ferrand, France
    Clin Chem Lab Med 45:546-8. 2007
    ..The aim of our study was to assess the efficiency of the usual alcohol biomarkers measured in cord blood to identify alcohol-exposed neonates immediately after birth...
  25. doi request reprint Partial compliance in schizophrenia and the impact on patient outcomes
    Pierre Michel Llorca
    Centre Medico Psychologique B, Centre Hospitalier Universitaire, Clermont Ferrand, France
    Psychiatry Res 161:235-47. 2008
    ..Long-acting risperidone may therefore bring together the benefits of the atypical antipsychotics with the long-acting injection delivery system required to build a platform for improved outcomes...
  26. ncbi request reprint Efficacy and safety of direct transition to risperidone long-acting injectable in patients treated with various antipsychotic therapies
    Hans Jurgen Moller
    Department of Psychiatry, University of Munich, Germany
    Int Clin Psychopharmacol 20:121-30. 2005
    ..Direct initiation of RLAI was effective and well tolerated. RLAI provides an advancement in the treatment options available for a wide range of patients requiring long-term antipsychotic therapy...
  27. ncbi request reprint Treatment of schizophrenia with long-acting injectable risperidone: a 12-month open-label trial of the first long-acting second-generation antipsychotic
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck, Austria
    J Clin Psychiatry 64:1250-7. 2003
    ..The long-term safety and efficacy of long-acting injectable risperidone, the first long-acting second-generation antipsychotic, were evaluated in stable patients with schizophrenia...
  28. ncbi request reprint Effects of cyamemazine on hERG, INa, ICa, Ito, Isus and IK1 channel currents, and on the QTc interval in guinea pigs
    William Crumb
    Zenas Technologies, New Orleans, LA, USA
    Eur J Pharmacol 532:270-8. 2006
    ..These non-clinical findings confirm the excellent cardiac safety records of cyamemazine during its 30 years of extensive therapeutic use...
  29. ncbi request reprint Bilateral deep brain stimulation of the globus pallidus to treat tardive dyskinesia
    Philippe Damier
    Centre Hospitalier Universitaire de Nantes, centre d investigation clinique, Nantes, France
    Arch Gen Psychiatry 64:170-6. 2007
    ..Tardive dyskinesia (TD) is a common and potentially disabling disorder induced by use of antipsychotic drugs for which medical treatment often gives disappointing results...