Ying Liu

Summary

Publications

  1. pmc C-MYC controlled TIP110 protein expression regulates OCT4 mRNA splicing in human embryonic stem cells
    Ying Liu
    Department of Cell Biology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas 76092, USA
    Stem Cells Dev 22:689-94. 2013
  2. pmc Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Stem Cells Dev 21:829-33. 2012
  3. pmc Suppression of HIV-1 Nef translation by Sam68 mutant-induced stress granules and nef mRNA sequestration
    Jorge Henao-Mejia
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Cell 33:87-96. 2009
  4. ncbi request reprint Requirement of an additional Sam68 domain for inhibition of human immunodeficiency virus type 1 replication by Sam68 dominant negative mutants lacking the nuclear localization signal
    Jizhong Zhang
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, United States
    Gene 363:67-76. 2005
  5. pmc Sam68 functions in nuclear export and translation of HIV-1 RNA
    Johnny J He
    Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    RNA Biol 6:384-6. 2009
  6. ncbi request reprint Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1
    Jizhong Zhang
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Walther Oncology Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 174:7995-8002. 2005
  7. ncbi request reprint HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes
    Albeiro López-Herrera
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biochim Biophys Acta 1741:55-64. 2005
  8. ncbi request reprint Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes
    Betty Y Zhou
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Cell Neurosci 27:296-305. 2004
  9. pmc TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA
    Blood 117:5643-51. 2011
  10. ncbi request reprint Tip110, the human immunodeficiency virus type 1 (HIV-1) Tat-interacting protein of 110 kDa as a negative regulator of androgen receptor (AR) transcriptional activation
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 279:21766-73. 2004

Collaborators

Detail Information

Publications29

  1. pmc C-MYC controlled TIP110 protein expression regulates OCT4 mRNA splicing in human embryonic stem cells
    Ying Liu
    Department of Cell Biology and Anatomy, University of North Texas Health Science Center, Fort Worth, Texas 76092, USA
    Stem Cells Dev 22:689-94. 2013
    ..Thus, TIP110 expression in ESCs regulates alternative splicing of OCT4, an event required for pluripotency of ESCs...
  2. pmc Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Stem Cells Dev 21:829-33. 2012
    ....
  3. pmc Suppression of HIV-1 Nef translation by Sam68 mutant-induced stress granules and nef mRNA sequestration
    Jorge Henao-Mejia
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Cell 33:87-96. 2009
    ....
  4. ncbi request reprint Requirement of an additional Sam68 domain for inhibition of human immunodeficiency virus type 1 replication by Sam68 dominant negative mutants lacking the nuclear localization signal
    Jizhong Zhang
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, United States
    Gene 363:67-76. 2005
    ....
  5. pmc Sam68 functions in nuclear export and translation of HIV-1 RNA
    Johnny J He
    Center for AIDS Research and Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    RNA Biol 6:384-6. 2009
    ..Elucidation of the precise molecular function of Sam68 in HIV-1 gene expression is clearly warranted and is expected to unambiguously establish Sam68 as an important host factor for HIV-1 replication...
  6. ncbi request reprint Neisseria gonorrhoeae enhances infection of dendritic cells by HIV type 1
    Jizhong Zhang
    Department of Microbiology and Immunology, Division of Infectious Diseases, Walther Oncology Center, Walther Oncology Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 174:7995-8002. 2005
    ..These results provide one potential mechanism through which GC infection increases HIV replication in patients infected with both GC and HIV...
  7. ncbi request reprint HIV-1 interaction with human mannose receptor (hMR) induces production of matrix metalloproteinase 2 (MMP-2) through hMR-mediated intracellular signaling in astrocytes
    Albeiro López-Herrera
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Biochim Biophys Acta 1741:55-64. 2005
    ..In addition, these results provide new evidence to support the notion that hMR is capable of eliciting intracellular signaling upon ligand binding...
  8. ncbi request reprint Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes
    Betty Y Zhou
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Mol Cell Neurosci 27:296-305. 2004
    ..In addition, these data suggest that astrocyte dysfunction contributes, at least in part, to Tat neurotoxicity and subsequently HIV-associated neuropathogenesis...
  9. pmc TIP110/p110nrb/SART3/p110 regulation of hematopoiesis through CMYC
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA
    Blood 117:5643-51. 2011
    ..These results demonstrate a role for TIP110 in the regulation of hematopoiesis, effects that are likely linked to TIP110 regulation of CMYC...
  10. ncbi request reprint Tip110, the human immunodeficiency virus type 1 (HIV-1) Tat-interacting protein of 110 kDa as a negative regulator of androgen receptor (AR) transcriptional activation
    Ying Liu
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 279:21766-73. 2004
    ..Taken together, these results indicate that Tip110 is a negative regulator of AR transcriptional activation, and may be directly involved in AR-related developmental, physiological, and pathological processes...
  11. pmc Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells
    Ying Liu
    Department of Microbiology and Immunology and the Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Exp Hematol 36:947-56. 2008
    ..To optimize culture and transduction conditions, we compared various lengths of time for prestimulation before transduction, transduction duration, and posttransduction cell culture...
  12. pmc Protection against human immunodeficiency virus type 1 Tat neurotoxicity by Ginkgo biloba extract EGb 761 involving glial fibrillary acidic protein
    Wei Zou
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut St, Indianapolis, IN 46202, USA
    Am J Pathol 171:1923-35. 2007
    ....
  13. pmc Up-regulation of hepatitis C virus replication and production by inhibition of MEK/ERK signaling
    Jean Ndjomou
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
    PLoS ONE 4:e7498. 2009
    ..The MEK/ERK signaling pathway positively regulates replication of many RNA viruses. However, whether and how this signaling pathway affects hepatitis C virus (HCV) replication and production is not well understood...
  14. pmc Lack of plakoglobin in epidermis leads to keratoderma
    Deqiang Li
    Riley Heart Research Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 287:10435-43. 2012
    ..Our findings provide important insights for understanding the pathogenesis of human palmoplantar keratoderma...
  15. ncbi request reprint Induction of C chemokine XCL1 (lymphotactin/single C motif-1 alpha/activation-induced, T cell-derived and chemokine-related cytokine) expression by HIV-1 Tat protein
    Byung oh Kim
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Immunol 172:1888-95. 2004
    ....
  16. pmc Inhibition of HIV-1 infection and replication by enhancing viral incorporation of innate anti-HIV-1 protein A3G: a non-pathogenic Nef mutant-based anti-HIV strategy
    Linden A Green
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46206, USA
    J Biol Chem 284:13363-72. 2009
    ..Taken together, these results indicate that Nef7.A3G can effectively restrict HIV infection and replication by restoring the virion incorporation of A3G, even in the presence of Vif...
  17. pmc Direct participation of Sam68, the 68-kilodalton Src-associated protein in mitosis, in the CRM1-mediated Rev nuclear export pathway
    Jinliang Li
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis 46202, USA
    J Virol 76:8374-82. 2002
    ....
  18. pmc Tip110 interacts with YB-1 and regulates each other's function
    Khalid Amine Timani
    University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    BMC Mol Biol 14:14. 2013
    ..Tip110 plays important roles in tumor immunobiology, pre-mRNA splicing, expression regulation of viral and host genes, and possibly protein turnover. It is clear that our understanding of Tip110 biological function remains incomplete...
  19. pmc Neuropathologies in transgenic mice expressing human immunodeficiency virus type 1 Tat protein under the regulation of the astrocyte-specific glial fibrillary acidic protein promoter and doxycycline
    Byung oh Kim
    Department of Microbiology and Immunology, The Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Am J Pathol 162:1693-707. 2003
    ....
  20. pmc CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor
    Ying Liu
    Department of Microbiology and Immunology and Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Virol 78:4120-33. 2004
    ..Taken together, these results demonstrate the direct involvement of hMR in HIV-1 infection of astrocytes and suggest that HIV-1 interaction with hMR plays an important role in HIV-1 neuropathogenesis...
  21. pmc Inhibition of HIV-1 entry by extracts derived from traditional Chinese medicinal herbal plants
    In Woo Park
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    BMC Complement Altern Med 9:29. 2009
    ..In the current study, we characterized a panel of extracts of traditional Chinese medicinal herbal plants for their activities against HIV-1 replication...
  22. pmc Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy
    Deqiang Li
    Riley Heart Research Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Hum Mol Genet 20:4582-96. 2011
    ..These findings have provided further insights for the pathogenesis of ARVC and potential therapeutic interventions...
  23. pmc Tip110 protein binds to unphosphorylated RNA polymerase II and promotes its phosphorylation and HIV-1 long terminal repeat transcription
    Weina Zhao
    From the Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202 and
    J Biol Chem 289:190-202. 2014
    ..Taken together, these findings have provided additional and mechanistic evidence to support Tip110 function in HIV-1 transcription. ..
  24. pmc Impaired function of Fanconi anemia type C-deficient macrophages
    Ying Liu
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA
    J Leukoc Biol 91:333-40. 2012
    ....
  25. ncbi request reprint Development and characterization of a recombinant cDNA-based hepatitis C virus system
    Jean Ndjomou
    Department of Microbiology and Immunology, Indiana University School of Medicine, R2 302, 950 W Walnut Street, Indianapolis, IN 46202, USA
    Biochem Biophys Res Commun 359:57-62. 2007
    ..These results support potential use of this system for studies on expression and processing of the HCV polyprotein and assembly and release of HCV-like particles...
  26. pmc Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis
    Deqiang Li
    Riley Heart Research Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Development 138:303-15. 2011
    ..Biochemical analyses indicate that Daam1 does not regulate cytoskeletal organization through RhoA, Rac1 or Cdc42. Our study highlights a crucial role for Daam1 in regulating the actin cytoskeleton and tissue morphogenesis...
  27. ncbi request reprint HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110
    Ying Liu
    Department of Microbiology and Immunology, Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    J Biol Chem 277:23854-63. 2002
    ..Taken together, these data demonstrate that Tip110 regulates Tat transactivation activity through direct interaction, and suggest that Tip110 is an important cellular factor for HIV-1 gene expression and viral replication...
  28. pmc Structure of C3PO and mechanism of human RISC activation
    Xuecheng Ye
    Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Nat Struct Mol Biol 18:650-7. 2011
    ..The current work supports a Dicer-independent mechanism for human RISC activation, in which Ago2 directly binds duplex siRNA and nicks the passenger strand, and then C3PO activates RISC by degrading the Ago2-nicked passenger strand...
  29. ncbi request reprint Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice
    Timothy B Campbell
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202 5181, USA
    Stem Cells Dev 16:347-54. 2007
    ..These results suggest that inhibition of CD26 may be one way to enhance engraftment of limiting numbers of stem cells during CB transplantation...