Margaret K Callahan

Summary

Publications

  1. ncbi Heat shock up-regulates lmp2 and lmp7 and enhances presentation of immunoproteasome-dependent epitopes
    Margaret K Callahan
    Center for Immunotherapy of Cancer and Infectious Diseases, University of Connecticut School of Medicine, Farmington, CT 06030, USA
    J Immunol 177:8393-9. 2006
  2. pmc Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation
    Margaret K Callahan
    Center for Immunotherapy of Cancer and Infectious Diseases, Department of Immunology, University of Connecticut School of Medicine, Farmington, CT 06030 1601, USA
    Proc Natl Acad Sci U S A 105:1662-7. 2008
  3. ncbi Resistance to CD4+CD25+ regulatory T cells and TGF-beta in Cbl-b-/- mice
    Elizabeth A Wohlfert
    Department of Medicine, Division of Rheumatic Diseases, and Center of Immunotherapy for Cancer and Infectious Diseases, University of Connecticut Health Center, Farmington, CT 06030, USA
    J Immunol 173:1059-65. 2004
  4. ncbi Treating human cancers with heat shock protein-peptide complexes: the road ahead
    Pramod K Srivastava
    University of Connecticut School of Medicine, Center for Immunotherapy of Cancer and Infectious Diseases, Department of Immunology, Farmington, CT 06030 1601, USA
    Expert Opin Biol Ther 9:179-86. 2009

Collaborators

Detail Information

Publications4

  1. ncbi Heat shock up-regulates lmp2 and lmp7 and enhances presentation of immunoproteasome-dependent epitopes
    Margaret K Callahan
    Center for Immunotherapy of Cancer and Infectious Diseases, University of Connecticut School of Medicine, Farmington, CT 06030, USA
    J Immunol 177:8393-9. 2006
    ..These findings show a novel immunological sequel to the cellular response to stress that may play a key role during fever or other homeostatic perturbations...
  2. pmc Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation
    Margaret K Callahan
    Center for Immunotherapy of Cancer and Infectious Diseases, Department of Immunology, University of Connecticut School of Medicine, Farmington, CT 06030 1601, USA
    Proc Natl Acad Sci U S A 105:1662-7. 2008
    ..The introduction of a stress-inducible component in these pathways has significant implications for their modulation during fever and infection...
  3. ncbi Resistance to CD4+CD25+ regulatory T cells and TGF-beta in Cbl-b-/- mice
    Elizabeth A Wohlfert
    Department of Medicine, Division of Rheumatic Diseases, and Center of Immunotherapy for Cancer and Infectious Diseases, University of Connecticut Health Center, Farmington, CT 06030, USA
    J Immunol 173:1059-65. 2004
    ..Coupled with recent reports of resistance to T(reg) in T(eff) exposed to LPS-treated dendritic cells, our present findings suggest that resistance to regulation may be a relevant mechanism in both normal immune function and autoimmunity...
  4. ncbi Treating human cancers with heat shock protein-peptide complexes: the road ahead
    Pramod K Srivastava
    University of Connecticut School of Medicine, Center for Immunotherapy of Cancer and Infectious Diseases, Department of Immunology, Farmington, CT 06030 1601, USA
    Expert Opin Biol Ther 9:179-86. 2009
    ..Two randomized Phase III trials have been completed recently...