Research Topics
Genomes and GenesSpecies | Limas KupcinskasSummaryAffiliation: Kaunas University of Medicine Country: Lithuania Publications
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Detail Information
Publications
Helicobacter pylori and non-malignant diseasesLimas Kupcinskas
Department of Gastroenterology, Kaunas University of Medicine, Mickeviciaus str 9, LT 44307 Kaunas, Lithuania
Helicobacter 10:26-33. 2005..pylori eradication does not cause gastro-esophageal reflux disease (GORD), however, a negative association between H. pylori and GORD does exist, especially in Asia, but the nature of this relationship should be further clarified...
De novo erosive esophagitis in duodenal ulcer patients related to pre-existing reflux symptoms, smoking, and patient age, but not to Helicobacter pylori eradication: a one-year follow-up studyLaimas Jonaitis
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, 50028 Kaunas, Lithuania
Medicina (Kaunas) 46:454-9. 2010..Therefore, we aimed to elucidate the role of H. pylori eradication and other factors in the development of erosive esophagitis in patients with duodenal ulcer...
[Modern attitude towards management of laryngopharyngeal form of gastroesophageal reflux disease. Lithuanian clinical practice guidelines for adults]Nora Siupsinskiene
Department of Otorhinolaryngology, Kaunas University of Medicine, Kaunas, Lithuania
Medicina (Kaunas) 43:832-9. 2007..Combined therapy for nonresponders is described. Algorithm for stopping the medication is recommended. These recommendations may provide an efficient and economical approach to the management of this problem...
Helicobacter pylori genotypes in Lithuanian patients with chronic gastritis and duodenal ulcerJolanta Miciuleviciene
Department of Gastroenterology, Kaunas University of Medicine, Lithuania
Medicina (Kaunas) 44:449-54. 2008..The aim of this study was to assess the relationship between cagPAI, vacA, and iceA status and severity of the disease in patients from Lithuania, infected by H. pylori...
The humoral immuneresponse to Helicobacter pylori infection in children with gastrointestinal symptomsDaiva Janulaityte-Gunther
Department of Microbiology, Kaunas University of Medicine, Lithuania
FEMS Immunol Med Microbiol 44:205-12. 2005..pylori infection in Lithuanian children is higher compared to Western Europe. The infection is acquired in early life. Diagnosing H. pylori infection, serology is helpful, but endoscopy/histology remains as gold standard...
NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel diseaseJurgita Sventoraityte
Department of Gastroenterology, Kaunas University of Medicine, A Mickeviciaus Street 9, LT 44307 Kaunas, Lithuania
World J Gastroenterol 16:359-64. 2010..To investigate the frequency of NOD2, IL23R and ATG16L1 genetic variants in a case-control panel for inflammatory bowel disease (IBD) from Lithuania...
Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms are not associated with premalignant gastric conditions: a combined haplotype analysisLimas Kupcinskas
Department of Gastroenterology, Kaunas University of Medicine, Kaunas, Lithuania
Eur J Gastroenterol Hepatol 22:1189-95. 2010..Here, IL1B and IL1RN polymorphisms were analyzed as genotypes and haplotypes in relation to the presence of atrophic gastritis (AG) and intestinal metaplasia in the stomach...
Gastroesophageal reflux disease after Helicobacter pylori eradication in gastric ulcer patients: a one-year follow-up studyLaimas Jonaitis
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
Medicina (Kaunas) 44:211-5. 2008....
Hepatic venous pressure gradient measurement in patients with liver cirrhosis: a correlation with disease severity and variceal bleedingVilma Silkauskaite
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, Kaunas, Lithuania
Medicina (Kaunas) 45:8-13. 2009..The aim of present study was to evaluate relationships between degree of portal hypertension, severity of the disease, and bleeding status in patients with liver cirrhosis...
Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled studyLimas Kupcinskas
Kaunas University of Medicine, 50009 Kaunas, Lithuania
Phytomedicine 15:391-9. 2008..The aim of this study was to evaluate the efficacy of the natural antioxidant astaxanthin in functional dyspepsia in different doses and compared with placebo...
Predictors of premature delivery in patients with intrahepatic cholestasis of pregnancyJurate Kondrackiene
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu Street 2, Kaunas 50009, Lithuania
World J Gastroenterol 13:6226-30. 2007..To evaluate the predictive value of clinical symptoms and biochemical parameters for prematurity in intrahepatic cholestasis of pregnancy (ICP)...
[Diagnostics of laryngopharyngeal form of gastroesophageal reflux disease for adults (Lithuanian clinical practice guidelines)]Ruta Pribuisiene
Department of Otorhinolaryngology, Kaunas University of Medicine, Kaunas, Lithuania
Medicina (Kaunas) 43:508-15. 2007..The guidelines are designed for the otorhinolaryngologists, gastroenterologists, and general practitioners...
Diagnostic sensitivity and specificity of laryngoscopic signs of reflux laryngitisRuta Pribuisiene
Department of Otorhinolaryngology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
Medicina (Kaunas) 44:280-7. 2008..To assess the diagnostic sensitivity and specificity of the laryngoscopic signs of reflux laryngitis...
Liver diseases unique to pregnancyJurate Kondrackiene
J Kondrackiene, Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
Medicina (Kaunas) 44:337-45. 2008..The correct diagnosis is critical, as any delay can result in morbidity or mortality of both the mother and fetus. Early delivery and advances in supportive management are the only available option for improving the prognosis...
Precancerous gastric conditions in high Helicobacter pylori prevalence areas: comparison between Eastern European (Lithuanian, Latvian) and Asian (Taiwanese) patientsLaimas Jonaitis
Department of Gastroenterology, Kaunas University of Medicine, Kaunas, Lithuania
Medicina (Kaunas) 43:623-9. 2007....
Helicobacter pylori antibodies and gastric cancer: a gender-related differenceDaiva Janulaityte-Gunther
Department of Microbiology, Kaunas University of Medicine, Mickeviciaus 9, LT 4430 Kaunas, Lithuania
FEMS Immunol Med Microbiol 44:191-5. 2005..H. pylori seems, however, to be a more important for development of gastric cancer in females than in males or males may have more confounding risk factors for gastric cancer than females...
Acute liver failure in LithuaniaDalia Adukauskiene
Department of Intensive Care, Kaunas University of Medicine, Kaunas, Lithuania
Medicina (Kaunas) 44:536-40. 2008..The aim of our study was to analyze the causes, outcomes, and prognostic factors of ALF in patients referred to tertiary care center in Lithuania...
Laryngeal examination is superior to endoscopy in the diagnosis of the laryngopharyngeal form of gastroesophageal reflux diseaseLaimas Jonaitis
Department of Gastroenterology, Kaunas University of Medicine, Kaunas, Lithuania
Scand J Gastroenterol 41:131-7. 2006..The purpose of this study was to evaluate the role of endoscopic and laryngologic examination in the diagnosis of LF GERD and to create a laryngoscopic reflux index (LRI)...
Incidence of inflammatory bowel disease in kaunas region, lithuaniaGediminas Kiudelis
Department of Gastroenterology, Medical Academy, Lithuanian University of Health Sciences, Eiveniu 2, 50028 Kaunas, Lithuania
Medicina (Kaunas) 48:431-5. 2012..The incidence of Crohn's disease was low and very similar to other countries of Eastern Europe. Age at onset of the diseases appeared to be older than that reported in the Western industrialized countries...
Immune system alterations in patients with inflammatory bowel disease during remissionJurgita Sventoraityte
Department of Gastroenterology, Kaunas University of Medicine, Kaunas, Lithuania
Medicina (Kaunas) 44:27-33. 2008..The aim of this study was to evaluate cytokine profile in patients with different forms of inflammatory bowel disease - ulcerative colitis and Crohn's disease - during clinical remission phase...
Intrahepatic cholestasis of pregnancy-current achievements and unsolved problemsJurate Kondrackiene
Department of Gastroenterology, Kaunas University of Medicine, Kaunas 50009, Lithuania
World J Gastroenterol 14:5781-8. 2008..Clinical trials are required to identify the most suitable monitoring modalities that can specifically predict poor perinatal outcome. This article aims to review current achievements and unsolved problems of ICP...
An unusual case of bleeding from stomach due to a giant diospyrobezoarJolanta Sumskiene
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
Medicina (Kaunas) 45:476-9. 2009..Such pathology potentially could be prevented by dietary advice...
Prevalence of hepatitis B virus chronic carriers and risk factors for hepatitis B virus infection among Lithuanian army soldiersLimas Kupcinskas
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, Kaunas, LT 50009 Lithuania
Mil Med 172:625-7. 2007..Study data proved the need for health promotion, prophylactic vaccination, and monitoring programs at the Lithuanian Armed Forces...
Disease-specific health-related quality of life and its determinants in liver cirrhosis patients in LithuaniaJolanta Sumskiene
Department of Gastroenterology, Kaunas University of Medicine, A.Mickeviciaus Street 9, Kaunas LT-44307, Lithuania
World J Gastroenterol 12:7792-7. 2006..CONCLUSION: QOL was significantly impaired in all CLDQ domains in liver cirrhosis patients. Increase in severity of disease was the major factor associated with poorer QOL...
Evaluation of a novel 14C-urea breath test "Heliprobe" in diagnosis of Helicobacter pylori infectionLaimas Virginijus Jonaitis
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
Medicina (Kaunas) 43:32-5. 2007..The aim of our study was to establish the diagnostic value of the novel, inexpensive, quick, and convenient to use (14)C-urea breath test "Heliprobe", Noster AB, Sweden...
A 1 year follow-up study of the consequences of Helicobacter pylori eradication in duodenal ulcer patients: unchanged frequency of erosive oesophagitis and decreased prevalence of non-erosive gastro-oesophageal reflux diseaseLimas Kupcinskas
Department of Gastroenterology, Kaunas University of Medicine, Lithuania
Eur J Gastroenterol Hepatol 16:369-74. 2004..pylori eradication, (2) patients with persistent H. pylori infection after attempts at eradication, and (3) controls in whom H. pylori eradication had not been attempted...
Influence of wrap length on the effectiveness of Nissen and Toupet fundoplication: a prospective randomized studyAntanas Mickevicius
Surgery Department, Kaunas University of Medicine, S Lozoraicio 32, Kaunas 50116, Lithuania
Surg Endosc 22:2269-76. 2008..Much less attention has been paid to the fundic wrap length. This study aimed to compare the effectiveness of two different wrap lengths among the patients undergoing partial or total fundoplication...
High frequency of the c.3207C>A (p.H1069Q) mutation in ATP7B gene of Lithuanian patients with hepatic presentation of Wilson's diseaseLaimutis Kucinskas
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, Kaunas LT 50009, Lithuania
World J Gastroenterol 14:5876-9. 2008..To investigate the prevalence of the ATP7B gene mutation in patients with hepatic presentation of Wilson's disease (WD) in Lithuania...
Perceptual and acoustic characteristics of voice changes in reflux laryngitis patientsRuta Pribuisiene
Department of Otolaryngology, Kaunas University of Medicine, Kaunas, Lithuania
J Voice 20:128-36. 2006..The results of the study demonstrated that multidimensional voice assessment documented deteriorated voice quality and restricted phonation capabilities in the tested group of RL patients...
[Dietary characteristics of patients with inflammatory bowel diseases]Aida Zvirbliene
Department of Gastroenterology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania
Medicina (Kaunas) 42:895-9. 2006..To evaluate nutritional status and dietary habits of Lithuanian patients with ulcerative colitis and Crohn's disease and to compare with those of healthy controls...
Efficacy and safety of ursodeoxycholic acid versus cholestyramine in intrahepatic cholestasis of pregnancyJurate Kondrackiene
Department of Gastroenterology, Kaunas University of Medicine, Kaunas, Lithuania
Gastroenterology 129:894-901. 2005..The aim of this randomized study was to evaluate the efficacy and safety of ursodeoxycholic acid in comparison with cholestyramine...
What Bizzozero never could imagine - Helicobacter pylori today and tomorrowDaiva Janulaityte-Gunther
Department of Microbiology, Kaunas University of Medicine, A Mickeviciaus 9, 3000 Kaunas, Lithuania
Medicina (Kaunas) 39:542-9. 2003..From large epidemiological studies made during the last twenty years as well as from microbiological research we have learned much more about this in the beginning nameless and mysterious bacterium...
Gastric inflammatory markers and interleukins in patients with functional dyspepsia treated with astaxanthinLeif Percival Andersen
Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
FEMS Immunol Med Microbiol 50:244-8. 2007..1999). These dietary conditions are impossible in studies involving humans, and may be due to the minor effect when the host have access to antioxidants in their diet...
Pantoprazole 20 mg on demand is effective in the long-term management of patients with mild gastro-oesophageal reflux diseaseSuleiman Kaspari
Private Practice, , Germany
Eur J Gastroenterol Hepatol 17:935-41. 2005..Hence, on-demand treatment with pantoprazole 20 mg is safe and effective in maintaining control of the symptoms heartburn, acid regurgitation and pain on swallowing symptoms in patients with GORD grade 0/I with superiority to placebo...
Gastric inflammatory markers and interleukins in patients with functional dyspepsia, with and without Helicobacter pylori infectionLeif P Andersen
Department of Clinical Microbiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
FEMS Immunol Med Microbiol 44:233-8. 2005..001). By using an index of inflammatory markers trends can be summarized and thereby significant which may be of importance when gastric inflammation is investigated in children and patients with functional dyspepsia...
Combined serum IgG response to Helicobacter pylori VacA and CagA predicts gastric cancerDaiva Janulaityte Günther
Department of Microbiology, University of Medicine, Kaunas, Lithuania
FEMS Immunol Med Microbiol 50:220-5. 2007..The detection of antibodies to 94- and 30-kDa bands, in association with the determination of serum antibodies to CagA+/VacA+, may have a prospective value in assessment of the risk of developing of gastric cancer...
