Fabio Santos Lira

Summary

Publications

  1. pmc Long-term interdisciplinary therapy reduces endotoxin level and insulin resistance in obese adolescents
    Fabio S Lira
    Departamento de Fisiologia, Rua Botucatu nº 862 Vila Clementino, Sao Paulo, Brazil
    Nutr J 11:74. 2012
  2. pmc Sleep duration in elderly obese patients correlated negatively with intake fatty
    Aline Alves Santana
    Laboratorio de Fisiologia e Bioquimica do Exercicio, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Lipids Health Dis 11:99. 2012
  3. pmc Gut-central nervous system axis is a target for nutritional therapies
    Gustavo D Pimentel
    Department of Internal Medicine, State University of Campinas, Campinas, Brazil
    Nutr J 11:22. 2012
  4. pmc Dietary whey protein lessens several risk factors for metabolic diseases: a review
    Gabriela T D Sousa
    Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo USP, Sao Paulo SP, Brazil
    Lipids Health Dis 11:67. 2012
  5. doi request reprint Both adiponectin and interleukin-10 inhibit LPS-induced activation of the NF-κB pathway in 3T3-L1 adipocytes
    Fabio Santos Lira
    Departamento de Fisiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Cytokine 57:98-106. 2012
  6. pmc Hypothalamic inflammation is reversed by endurance training in anorectic-cachectic rats
    Fabio S Lira
    Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of Sao Paulo USP, Sao Paulo, SP Brazil
    Nutr Metab (Lond) 8:60. 2011
  7. pmc β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway
    Gustavo D Pimentel
    Department of Physiology of Nutrition, Federal University of Sao Paulo UNIFESP, Sao Paulo, SP Brazil
    Nutr Metab (Lond) 8:11. 2011
  8. pmc Obesity, diabetes and OSAS induce of sleep disorders: exercise as therapy
    Eduardo S Alves
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Brazil
    Lipids Health Dis 10:148. 2011
  9. pmc Exercise training improves sleep pattern and metabolic profile in elderly people in a time-dependent manner
    Fabio S Lira
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Brasil
    Lipids Health Dis 10:1-6. 2011
  10. pmc Acute exhaustive exercise regulates IL-2, IL-4 and MyoD in skeletal muscle but not adipose tissue in rats
    José C Rosa Neto
    Department of Physiology of Nutrition, Federal University of Sao Paulo, Sao Paulo, Brazil
    Lipids Health Dis 10:97. 2011

Collaborators

Detail Information

Publications31

  1. pmc Long-term interdisciplinary therapy reduces endotoxin level and insulin resistance in obese adolescents
    Fabio S Lira
    Departamento de Fisiologia, Rua Botucatu nº 862 Vila Clementino, Sao Paulo, Brazil
    Nutr J 11:74. 2012
    ....
  2. pmc Sleep duration in elderly obese patients correlated negatively with intake fatty
    Aline Alves Santana
    Laboratorio de Fisiologia e Bioquimica do Exercicio, Universidade do Extremo Sul Catarinense, Criciuma, SC, Brazil
    Lipids Health Dis 11:99. 2012
    ..The purpose of the present study was to evaluate the relationship between sleep duration and dietary habits in elderly obese patients treated at an institute of cardiology...
  3. pmc Gut-central nervous system axis is a target for nutritional therapies
    Gustavo D Pimentel
    Department of Internal Medicine, State University of Campinas, Campinas, Brazil
    Nutr J 11:22. 2012
    ..Therefore, this review highlights the relationship between the gut-central nervous system axis and targets for nutritional therapies...
  4. pmc Dietary whey protein lessens several risk factors for metabolic diseases: a review
    Gabriela T D Sousa
    Departamento de Fisiologia e Biofisica, Instituto de Ciencias Biomedicas, Universidade de Sao Paulo USP, Sao Paulo SP, Brazil
    Lipids Health Dis 11:67. 2012
    ..Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress...
  5. doi request reprint Both adiponectin and interleukin-10 inhibit LPS-induced activation of the NF-κB pathway in 3T3-L1 adipocytes
    Fabio Santos Lira
    Departamento de Fisiologia, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Cytokine 57:98-106. 2012
    ..In addition, inhibition of NF-κB signaling pathways may be an excellent strategy for the treatment of inflammation in obese individuals...
  6. pmc Hypothalamic inflammation is reversed by endurance training in anorectic-cachectic rats
    Fabio S Lira
    Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of Sao Paulo USP, Sao Paulo, SP Brazil
    Nutr Metab (Lond) 8:60. 2011
    ..abstract:..
  7. pmc β-Hydroxy-β-methylbutyrate (HMβ) supplementation stimulates skeletal muscle hypertrophy in rats via the mTOR pathway
    Gustavo D Pimentel
    Department of Physiology of Nutrition, Federal University of Sao Paulo UNIFESP, Sao Paulo, SP Brazil
    Nutr Metab (Lond) 8:11. 2011
    ..Expression of the insulin receptor was increased only in liver. Thus, our results suggest that HMβ supplementation can be used to increase muscle mass without adverse health effects...
  8. pmc Obesity, diabetes and OSAS induce of sleep disorders: exercise as therapy
    Eduardo S Alves
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Brazil
    Lipids Health Dis 10:148. 2011
    ..At present, our group is investigating the effect of chronic endurance exercise on sleep alterations...
  9. pmc Exercise training improves sleep pattern and metabolic profile in elderly people in a time-dependent manner
    Fabio S Lira
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Brasil
    Lipids Health Dis 10:1-6. 2011
    ..Suggesting that this population requires training strategy modifications as to ensure consistent alterations regarding metabolism...
  10. pmc Acute exhaustive exercise regulates IL-2, IL-4 and MyoD in skeletal muscle but not adipose tissue in rats
    José C Rosa Neto
    Department of Physiology of Nutrition, Federal University of Sao Paulo, Sao Paulo, Brazil
    Lipids Health Dis 10:97. 2011
    ....
  11. pmc Supplementing alpha-tocopherol (vitamin E) and vitamin D3 in high fat diet decrease IL-6 production in murine epididymal adipose tissue and 3T3-L1 adipocytes following LPS stimulation
    Fabio S Lira
    Departamento de Fisiologia, Universidade Federal de Sao Paulo, Brasil
    Lipids Health Dis 10:37. 2011
    ..Additionally, we measured the effects of vitamin E and vitamin D3 treatment on LPS-stimulated 3T3-L1 adipocytes IL-6 and IL-10 secretion...
  12. pmc Sleep deprivation affects inflammatory marker expression in adipose tissue
    José C Rosa Neto
    Departmento de Fisiologia da Nutrição, Universidade Federal de São Paulo UNIFESP São Paulo SP, Brazil
    Lipids Health Dis 9:125. 2010
    ..We also assessed lipid profiles and serum levels of corticosterone, leptin, and adiponectin after 96 hours of sleep deprivation...
  13. pmc PAKs supplement improves immune status and body composition but not muscle strength in resistance trained individuals
    Frederigo G Romero
    Department of Biodynamic, Mackenzie Presbiterian University, Sao Paulo, Brazil
    J Int Soc Sports Nutr 7:36. 2010
    ..These results indicate that, a mixed formula supplement is able to improve immune status and body composition but not maximum strength in recreational strength trained subjects in a 4 weeks period...
  14. doi request reprint Visceral fat decreased by long-term interdisciplinary lifestyle therapy correlated positively with interleukin-6 and tumor necrosis factor-α and negatively with adiponectin levels in obese adolescents
    Fabio Santos Lira
    Postgraduate Program of Nutrition, Federal University of Sao Paulo UNIFESP, São Paulo SP 04020 060, Brazil
    Metabolism 60:359-65. 2011
    ....
  15. pmc Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile
    Fabio S Lira
    Molecular Biology of the Cell Group, Institute of Biomedical Sciences, Department of Cell and Developmental Biology, University of Sao Paulo, Brazil
    Diabetol Metab Syndr 2:31. 2010
    ..The effects of chronic aerobic exercise upon lipid profile has been previously demonstrated, but few studies showed this effect under resistance exercise conditions...
  16. ncbi request reprint Is acute supramaximal exercise capable of modulating lipoprotein profile in healthy men?
    Fabio Santos Lira
    Institute of Biomedical Sciences, Department of Cell and Developmental Biology, University of Sao Paulo, Brazil
    Eur J Clin Invest 40:759-65. 2010
    ..This study examined the effects of acute supramaximal exercise (approximately 115% VO(2max)) on the blood lipid profile for three different carbohydrate (CHO) storage levels (control, low and high)...
  17. pmc Conjugated Linoleic Acid: good or bad nutrient
    Daniela C Goncalves
    Department of Physiology, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo SP, Brazil
    Diabetol Metab Syndr 2:62. 2010
    ..However, our results show that, CLA appears to be not a good supplement in patients with cachexia...
  18. pmc Inflammation and adipose tissue: effects of progressive load training in rats
    Fabio S Lira
    Department of Physiology of Nutrition, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    Lipids Health Dis 9:109. 2010
    ..In the present study, we investigated the regulation of cytokine production in the adipose tissue of rats after an overtraining-inducing exercise protocol...
  19. pmc Dose and latency effects of leucine supplementation in modulating glucose homeostasis: opposite effects in healthy and glucocorticoid-induced insulin-resistance states
    Nelo Eidy Zanchi
    Laboratory of Applied Nutrition and Metabolism, School of Physical Education and Sports, University of Sao Paulo, Sao Paulo, Brazil
    Nutrients 4:1851-67. 2012
    ....
  20. ncbi request reprint Chronic low frequency/low volume resistance training reduces pro-inflammatory cytokine protein levels and TLR4 mRNA in rat skeletal muscle
    Nelo Eidy Zanchi
    Laboratory of Applied Nutrition and Metabolism, Physical Education and Sport School, University of Sao Paulo, Av Prof Mello Moraes, 65, Sao Paulo, SP, 05508 900, Brazil
    Eur J Appl Physiol 109:1095-102. 2010
    ....
  21. doi request reprint Depot-specific modulation of adipokine levels in rat adipose tissue by diet-induced obesity: the effect of aerobic training and energy restriction
    Alex Shimura Yamashita
    Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil
    Cytokine 52:168-74. 2010
    ..508); and adiponectin (r=0.342). These results suggest a tissue-specific heterogeneous response in adipokines level. The combination of the protocols (aerobic training and energy restriction) did not induce an enhanced effect...
  22. pmc Low-grade inflammation and spinal cord injury: exercise as therapy?
    Eduardo da Silva Alves
    Departamento de Psicobiologia, Universidade Federal de Sao Paulo, UNIFESP, Campus Sao Paulo, 04020 050 São Paulo, Brazil
    Mediators Inflamm 2013:971841. 2013
    ....
  23. pmc Can high altitude influence cytokines and sleep?
    Valdir de Aquino Lemos
    Departamento de Psicobiologia, Campus Sao Paulo, UNIFESP, Sao Paulo, SP, Brazil
    Mediators Inflamm 2013:279365. 2013
    ....
  24. pmc Renewed avenues through exercise muscle contractility and inflammatory status
    Nelo Eidy Zanchi
    Laboratory of Applied Nutrition and Metabolism, Physical Education and Sport School, University of Sao Paulo, 05508 030 São Paulo, Brazil
    ScientificWorldJournal 2012:584205. 2012
    ..This paper aims to describe specific data from the literature regarding the effects of exercise on inflammatory diseases in order to promote a more sophisticated perspective on the anti-inflammatory effects of exercise...
  25. doi request reprint Experimental chronic low-frequency resistance training produces skeletal muscle hypertrophy in the absence of muscle damage and metabolic stress markers
    Nelo Eidy Zanchi
    Laboratory of Applied Nutrition and Metabolism, Physical Education and Sport School, University of Sao Paulo, Sao Paulo, Brazil
    Cell Biochem Funct 28:232-8. 2010
    ..Such information may have practical applications if reproduced in situations where skeletal muscle hypertrophy is desired but high mechanical stimuli of skeletal muscle and inflammation are not...
  26. doi request reprint Chronic resistance training decreases MuRF-1 and Atrogin-1 gene expression but does not modify Akt, GSK-3beta and p70S6K levels in rats
    Nelo Eidy Zanchi
    Laboratory of Applied Nutrition and Metabolism, Physical Education and Sport School, University of Sao Paulo, Av Prof Mello Moraes, 65, Sao Paulo, SP, 05508 900, Brazil
    Eur J Appl Physiol 106:415-23. 2009
    ..However, proteolytic gene expression is modified even after a prolonged resistance training regimen leading to moderate skeletal muscle hypertrophy...
  27. doi request reprint HMB supplementation: clinical and athletic performance-related effects and mechanisms of action
    Nelo Eidy Zanchi
    Laboratory of Applied Nutrition and Metabolism, Physical Education and Sports School, University of Sao Paulo, Sao Paulo, Brazil
    Amino Acids 40:1015-25. 2011
    ..Moreover, the possible mechanisms of cell signaling regulation leading to increases and/or sparing (during catabolic conditions) of skeletal muscle mass are discussed in detail based on the recent literature...
  28. doi request reprint Autonomic changes in young smokers: acute effects of inspiratory exercise
    Fernando Rodrigues
    Human Movement Laboratory, Sao Judas Tadeu University, Av Taquari, 546, Sao Paulo, SP, 03166 000, Brazil
    Clin Auton Res 23:201-7. 2013
    ..However, little is known about the early consequences of smoking and the acute effects of a single inspiratory muscle exercise session (IME). We evaluated the acute effects of an IME on cardiac parameters of young smokers...
  29. pmc Strategies for reducing body fat mass: effects of liposuction and exercise on cardiovascular risk factors and adiposity
    Fabiana Braga Benatti
    School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
    Diabetes Metab Syndr Obes 4:141-54. 2011
    ..Consequently, one could suggest that liposuction and exercise appear to be safe and effective strategies for either the treatment of metabolic disorders or aesthetic purposes...
  30. doi request reprint High altitude exposure impairs sleep patterns, mood, and cognitive functions
    Valdir de Aquino Lemos
    Departamento de Psicobiologia Campus São Paulo, Universidade Federal de Sao Paulo, Sao Paulo, Brasil
    Psychophysiology 49:1298-306. 2012
    ..Vigor, attention, visual and working memory, concentration, executive functions, inhibitory control, and speed of mental processing worsened. Changes in sleep patterns can modulate mood and cognition after 24 h...