Topical application of a gentamicin-collagen sponge combined with systemic antibiotic therapy for the treatment of diabetic foot infections of moderate severity: a randomized, controlled, multicenter clinical trialBenjamin A Lipsky
Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA, USA
J Am Podiatr Med Assoc 102:223-32. 2012
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Executive summary: 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infectionsBenjamin A Lipsky
Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA
Clin Infect Dis 54:1679-84. 2012
..Employing multidisciplinary foot teams improves outcomes. Clinicians and healthcare organizations should attempt to monitor, and thereby improve, their outcomes and processes in caring for DFIs...
- 2012 Infectious Diseases Society of America clinical practice guideline for the diagnosis and treatment of diabetic foot infections
Benjamin A Lipsky
Department of Medicine, University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
Clin Infect Dis 54:e132-73. 2012
..Employing multidisciplinary foot teams improves outcomes. Clinicians and healthcare organizations should attempt to monitor, and thereby improve, their outcomes and processes in caring for DFIs...
- Skin and soft tissue infections in hospitalised patients with diabetes: culture isolates and risk factors associated with mortality, length of stay and cost
B A Lipsky
VA Puget Sound Health Care System, General Internal Medicine S 111 PCC, University of Washington, 1660 S Columbian Way, Seattle, WA, USA
Diabetologia 53:914-23. 2010
..Skin and soft tissue infections (SSTIs) cause substantial morbidity in persons with diabetes. There are few data on pathogens or risk factors associated with important outcomes in diabetic patients hospitalised with SSTIs...
- Treatment of bacterial prostatitis
Benjamin A Lipsky
General Internal Medicine Service, Veterans Affairs Puget Sound Health Care System, Seattle, Washington, USA
Clin Infect Dis 50:1641-52. 2010
..We review recent pharmacological and clinical data on treating bacterial prostatitis...
Developing and validating a risk score for lower-extremity amputation in patients hospitalized for a diabetic foot infectionBenjamin A Lipsky
Department of Medicine, University of Washington, Seattle, WA, USA
Diabetes Care 34:1695-700. 2011
..We sought to develop and validate a risk score to aid in the early identification of patients hospitalized for diabetic foot infection who are at highest risk of LEA...
- The role of diabetes mellitus in the treatment of skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: results from three randomized controlled trials
Benjamin A Lipsky
Medical Service, VA Puget Sound Health Care System, 1880 S Columbian Way S 111 GIMC, Seattle, WA 98108 1587, USA
Int J Infect Dis 15:e140-6. 2011
..To compare outcomes of treating complicated skin and skin structure infections (cSSSI) caused by methicillin-resistant Staphylococcus aureus (MRSA) with linezolid versus vancomycin in diabetic and non-diabetic patients...
- Predicting bacteremia among patients hospitalized for skin and skin-structure infections: derivation and validation of a risk score
Benjamin A Lipsky
General Medical Service, Veterans Affairs Puget Sound Health Care System, Department of Medicine, University of Washington, Seattle, Washington 98108, USA
Infect Control Hosp Epidemiol 31:828-37. 2010
..We used selected demographic and clinical characteristics easily assessable at initial evaluation to develop a model for the early identification of patients with SSSI who are at higher risk for bacteremia...
- Principles and practice of antibiotic therapy of diabetic foot infections
B A Lipsky
University of Washington, School of Medicine, Seattle, USA
Diabetes Metab Res Rev 16:S42-6. 2000
..Various non-antimicrobial adjunct therapies may sometimes be helpful. Published in 2000 by John Wiley & Sons, Ltd...
- Evidence-based antibiotic therapy of diabetic foot infections
B A Lipsky
Department of Medicine, University of Washington School of Medicine and Medical Service, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108 1597, USA
FEMS Immunol Med Microbiol 26:267-76. 1999
..Suggested regimens based on the severity of infection are provided...
- Expert opinion on the management of infections in the diabetic foot
B A Lipsky
VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
Diabetes Metab Res Rev 28:163-78. 2012
..If properly treated, most diabetic foot infections can be cured. Providers practising in developing countries, and their patients, face especially challenging situations...
- Urinary catheters: what type do men and their nurses prefer?
S Saint
Department of Medicine, University of Michigan Health System, Health Services Research and Development, Ann Arbor Veterans Affairs Medical Center, 48109 0376, USA
J Am Geriatr Soc 47:1453-7. 1999
..We sought to determine the beliefs of both older male patients and nursing staff about the relative merits and problems of condom and indwelling catheters...
- Improving the appropriateness of vancomycin use by sequential interventions
B A Lipsky
Veterans Affairs Puget Sound Health Care System, and the Department of Medicine, University of Washington, Seattle 98108 1532, USA
Am J Infect Control 27:84-91. 1999
..However, educational interventions provided only transient benefit on institutional prescribing patterns...
- The evaluation and treatment of complicated skin and skin structure infections
Paul B Cornia
University of Washington School of Medicine, Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System and Department of Medicine, Seattle, WA 98108 1597, USA
Expert Opin Pharmacother 9:717-30. 2008
..Skin and skin structure infections are frequently encountered in clinical practice. Fortunately, these infections usually produce only mild to moderate symptoms and signs. Some, however, are severe and may even be life-threatening...
- Diagnosis and treatment of diabetic foot infections
Benjamin A Lipsky
Medical Service, Veterans Affairs Puget Sound Health Care System, and Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98108-9804, USA
Clin Infect Dis 39:885-910. 2004
- Optimising antimicrobial therapy in diabetic foot infections
Nalini Rao
Division of Infectious Disease, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232 1381, USA
Drugs 67:195-214. 2007
..Certain other organisms, such as Pseudomonas aeruginosa and Enterococcus spp., while potentially pathogenic, are often colonisers that do not require targeted therapy...
- Clinical predictors of treatment failure for diabetic foot infections: data from a prospective trial
Benjamin A Lipsky
Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, WA 98108 1597, USA
Int Wound J 4:30-8. 2007
..Increased white blood cell count and severe UT wound grade at baseline, but not other features, were significant independent and additive risk factors for clinical failure in patients treated for a diabetic foot infection...
- Treating diabetic foot infections with sequential intravenous to oral moxifloxacin compared with piperacillin-tazobactam/amoxicillin-clavulanate
Benjamin A Lipsky
VA Puget Sound Health Care System and University of Washington, Seattle, WA, USA
J Antimicrob Chemother 60:370-6. 2007
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- Topical antimicrobial therapy for treating chronic wounds
Benjamin A Lipsky
Veterans Affairs Puget Sound Health Care System and 2University of Washington, School of Medicine, Seattle, WA 98108, USA
Clin Infect Dis 49:1541-9. 2009
..We provide clinically relevant information on currently available topical antimicrobial agents...
- Which antimicrobial impregnated central venous catheter should we use? Modeling the costs and outcomes of antimicrobial catheter use
Kristin D Marciante
Pharmaceutical Outcomes Research and Policy Program, Department of Pharmacy, University of Washington, Seattle WA 98195, USA
Am J Infect Control 31:1-8. 2003
..It remains unclear whether minocycline/rifampin catheters are cost-effective for all high-risk patients or only those requiring longer-term catheterization...
- Using maximal sterile barriers to prevent central venous catheter-related infection: a systematic evidence-based review
Kent K Hu
Northwest Health Services Research and Development Program, Department of Medicine, University of Washington and VA Puget Sound HCS, 1660 South Columbian Way, HSR and D (152, Seattle, WA 98108, USA
Am J Infect Control 32:142-6. 2004
..While we believe the available evidence does support the use of maximal sterile barriers during routine insertion of central venous catheters, prospective studies and economic analyses would better clarify its value...
- Clinical problem-solving. Nothing to cough at--a 73-year-old man presented to the emergency department with a 4-day history of nonproductive cough that worsened at night
Paul B Cornia
Primary and Specialty Medical Care Service, Veterans Affairs Puget Sound Health Care System, and the Department of Medicine, University of Washington School of Medicine, Seattle, WA 98108-1597, USA
N Engl J Med 357:1432-7. 2007
- Are granulocyte colony-stimulating factors beneficial in treating diabetic foot infections?: A meta-analysis
Mario Cruciani
University of Washington, School of Medicine, Director, General Internal Medicine Clinic, VA Puget Sound Health Care System S 111 GIMC, 1660 South Columbian Way, Seattle, WA 98108 1597, USA
Diabetes Care 28:454-60. 2005
..To assess the value of granulocyte colony-stimulating factor (G-CSF) as adjunctive therapy for diabetic foot infections...
- Ertapenem versus piperacillin/tazobactam for diabetic foot infections (SIDESTEP): prospective, randomised, controlled, double-blinded, multicentre trial
Benjamin A Lipsky
University of Washington School of Medicine and Veterans Affairs Puget Sound Health Care System S 111 GIMC, 1660 S Columbian Way, Seattle, WA 98108, USA
Lancet 366:1695-703. 2005
..Our aim was to assess the efficacy and safety of ertapenem versus piperacillin/tazobactam for foot infections...
- New developments in diagnosing and treating diabetic foot infections
Benjamin A Lipsky
University of Washington, USA
Diabetes Metab Res Rev 24:S66-71. 2008
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- Commentary: indwelling urinary catheters in hospitalized patients: when in doubt, pull it out
Paul B Cornia
Primary and Specialty Medicine Service, Veterans Affairs Puget Sound Health Care System and the University of Washington School of Medicine, Seattle, Washington, USA
Infect Control Hosp Epidemiol 29:820-2. 2008
- Influenza vaccination rates of children in households with high-risk adults
Ru Chien Chi
Veterans Administration Puget Sound Health Care System, Seattle, WA, USA
Public Health Rep 125:192-8. 2010
..We evaluated influenza vaccine coverage among children to determine whether or not living with a high-risk adult predicts the likelihood of being vaccinated...
- Topical versus systemic antimicrobial therapy for treating mildly infected diabetic foot ulcers: a randomized, controlled, double-blinded, multicenter trial of pexiganan cream
Benjamin A Lipsky
Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98116 1597, USA
Clin Infect Dis 47:1537-45. 2008
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- Skin, soft tissue, bone, and joint infections in hospitalized patients: epidemiology and microbiological, clinical, and economic outcomes
Benjamin A Lipsky
VA Puget Sound Health Care System, Seattle, Washington 98108, USA
Infect Control Hosp Epidemiol 28:1290-8. 2007
..There are currently few published studies on the epidemiology and clinical and economic outcomes of these infections, whether acquired in the community or healthcare setting, in a large population...
