Partner characteristics predicting HIV-1 set point in sexually acquired HIV-1 among African seroconvertersJairam R Lingappa
University of Washington 325 Ninth Avenue, Box 359927 Seattle, WA 98104, USA
AIDS Res Hum Retroviruses 29:164-71. 2013
..Acyclovir use, BV among women source partners, and circumcision among male source partners may alter the set point by affecting transmitted virus inoculum in the source partners' genital compartment...
Estimating the impact of plasma HIV-1 RNA reductions on heterosexual HIV-1 transmission riskJairam R Lingappa
Department of Global Health, University of Washington, Seattle, Washington, United States of America
PLoS ONE 5:e12598. 2010
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Sensitivity and specificity of herpes simplex virus-2 serological assays among HIV-infected and uninfected urban UgandansJ Lingappa
Department of Global Health, University of Washington, Seattle, WA 98102, USA
Int J STD AIDS 21:611-6. 2010
..001). Of commercially available HSV-2 serological assays, Kalon alone, or Focus ELISA followed by Biokit confirmation perform best. Improved HSV-2 assays are needed for HSV-2 and HIV-1 public health activities in Africa...
Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposureJairam R Lingappa
Department of Global Health, University of Washington, Seattle, Washington, United States of America
PLoS ONE 6:e28632. 2011
..To minimize misclassification of HIV-1 risk, we quantified HIV-1 exposure, using data including plasma HIV-1 concentrations, gender, and condom use...
Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trialJairam R Lingappa
Department of Global Health, Seattle, WA, USA
Lancet 375:824-33. 2010
..Daily suppression of this herpes virus reduces plasma HIV-1 concentrations, but whether it delays HIV-1 disease progression is unknown. We investigated the effect of acyclovir on HIV-1 progression...