Multivariate analysis of neuronal interactions in the generalized partial least squares framework: simulations and empirical studiesFa Hsuan Lin
Harvard MIT Division of Health Sciences and Technology, Charlestown, MA 02446, USA
Neuroimage 20:625-42. 2003
..Overall, studies of synthetic and empirical data suggest that PLS analysis, using PCA decomposition, provides a stable and powerful tool for exploration of fMRI/behavior data...
Onset timing of cross-sensory activations and multisensory interactions in auditory and visual sensory corticesTommi Raij
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Bldg 149, 13 St, Charlestown, MA, USA
Eur J Neurosci 31:1772-82. 2010
..Audiovisual interactions started at 85 ms in the left auditory, 80 ms in the right auditory and 74 ms in the visual cortex, i.e., 3-21 ms after inputs from the two modalities converged...
- Cancellation of EEG and MEG signals generated by extended and distributed sources
Seppo P Ahlfors
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, Charlestown, 02129, USA
Hum Brain Mapp 31:140-9. 2010
..Furthermore, the selective cancellation may be used to explain some observed differences between EEG and MEG in terms of focal vs. widespread cortical activity...
- Attention-driven auditory cortex short-term plasticity helps segregate relevant sounds from noise
Jyrki Ahveninen
Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 108:4182-7. 2011
..In conclusion, a simple gain model alone cannot explain auditory selective attention. In nonprimary auditory cortices, attention-driven short-term plasticity retunes neurons to segregate relevant sounds from noise...
- Primary and multisensory cortical activity is correlated with audiovisual percepts
Margo McKenna Benoit
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02114, USA
Hum Brain Mapp 31:526-38. 2010
....
- Human posterior auditory cortex gates novel sounds to consciousness
Iiro P Jaaskelainen
Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 101:6809-14. 2004
..Our converging findings suggest that transient adaptation of feature-specific neurons within human posterior auditory cortex filters superfluous sounds from entering one's awareness...
- Dynamic magnetic resonance inverse imaging of human brain function
Fa Hsuan Lin
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
Magn Reson Med 56:787-802. 2006
..InI is expected to improve the time resolution of MRI and provide increased flexibility in the trade-off between spatial and temporal resolution for studies of dynamic activation patterns in the human brain...
- Stimulus-induced Rotary Saturation (SIRS): a potential method for the detection of neuronal currents with MRI
Thomas Witzel
Speech and Hearing Bioscience and Technology Program, Harvard MIT Division of Health Sciences and Technology, USA
Neuroimage 42:1357-65. 2008
..Magn. Reson. Med. 50, 40-49], but is potentially less encumbered by temporal and spatial cancellation effects...
- Functional MRI using regularized parallel imaging acquisition
Fa Hsuan Lin
Massachusetts General Hospital, Department of Radiology, MGH HMS MIT, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
Magn Reson Med 54:343-53. 2005
..Human motor and visual fMRI data acquired at different field strengths and array coils also demonstrate that regularized SENSE improves the detection of functionally active brain regions...
- Distributed current estimates using cortical orientation constraints
Fa Hsuan Lin
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
Hum Brain Mapp 27:1-13. 2006
..We also applied the method to in vivo auditory and somatosensory data...
- Task-modulated "what" and "where" pathways in human auditory cortex
Jyrki Ahveninen
Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, CNY 149 13th Street, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 103:14608-13. 2006
..This finding suggests that selective-attention effects are feature-specific in the human nonprimary auditory cortex and that they arise from enhanced tuning of receptive fields of task-relevant neuronal populations...
- MRI-constrained spectral imaging of benzodiazepine modulation of spontaneous neuromagnetic activity in human cortex
Jyrki Ahveninen
Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, CNY149 13th Street, Charlestown, MA 02129, USA
Neuroimage 35:577-82. 2007
..Anatomically constrained spectral imaging displays the cortical loci of drug effects on oscillatory brain activity, providing a novel tool for human pharmacological neuroimaging...
- Parallel input makes the brain run faster
Tommi Raij
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
Neuroimage 40:1792-7. 2008
..This arrangement could also allow very early top-down modulation of the bottom-up stream of sensory information...
- Event-related single-shot volumetric functional magnetic resonance inverse imaging of visual processing
Fa Hsuan Lin
MGH HST Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
Neuroimage 42:230-47. 2008
..Robust results from both single subject and group analyses demonstrate the sensitivity and feasibility of using volumetric InI in high temporal resolution investigations of human brain function...
Accelerated proton echo planar spectroscopic imaging (PEPSI) using GRAPPA with a 32-channel phased-array coilShang Yueh Tsai
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Magn Reson Med 59:989-98. 2008
..At 4-fold acceleration the mean CRLB for NAA, tCr, and Cho was less than 11%. In conclusion, the use of a 32-channel coil array and GRAPPA reconstruction can significantly reduce the measurement time for mapping brain metabolites...
- Parallel MRI reconstruction using variance partitioning regularization
Fa Hsuan Lin
Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan
Magn Reson Med 58:735-44. 2007
..Our anatomical and functional MRI results show that the VPR method can be applied to both static and dynamic MRI experiments to suppress noise amplification in parallel MRI reconstructions for improved image quality...
- Fast mapping of the T2 relaxation time of cerebral metabolites using proton echo-planar spectroscopic imaging (PEPSI)
Shang Yueh Tsai
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
Magn Reson Med 57:859-65. 2007
..Consistent spatial distributions of T2 were found in six healthy subjects, and disagreement among subjects was less than 10%. In summary, the PEPSI technique is a robust method to obtain fast mapping of metabolite T2...
- Sensitivity-encoded (SENSE) proton echo-planar spectroscopic imaging (PEPSI) in the human brain
Fa Hsuan Lin
MGH HMS MIT Athinoula A Martinos Center for Biomedical Imaging, Charlestown 02129, and Department of Radiology, Massachusetts General Hospital, Boston, USA
Magn Reson Med 57:249-57. 2007
..Thus, this technology is a promising means of reducing the scan times of 3D acquisitions and time-resolved 2D measurements...
- PROPELLER-EPI with parallel imaging using a circularly symmetric phased-array RF coil at 3.0 T: application to high-resolution diffusion tensor imaging
Tzu-Chao Chuang
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, R.O.C
Magn Reson Med 56:1352-8. 2006
..It is concluded that parallel PROPELLER-EPI is an effective technique that can substantially reduce susceptibility-induced geometric distortions at high field strength...
- Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimates
Fa Hsuan Lin
MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Building 149 13th St Charlestown, MA 02129, USA
Neuroimage 31:160-71. 2006
..The application of depth weighting to auditory and somatosensory experimental data illustrated the beneficial effect of depth weighting on the accuracy of spatiotemporal mapping of neuronal sources...
- PROPELLER EPI: an MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortions
Fu-Nien Wang
Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, R.O.C
Magn Reson Med 54:1232-40. 2005
..A higher signal-to-noise ratio (SNR) compared to single-shot EPI at an identical total scan time was achieved, which is advantageous for routine DTI applications in clinical practice...
- Spectral spatiotemporal imaging of cortical oscillations and interactions in the human brain
Fa-Hsuan Lin
MGH-MIT-MHS Athinoula A. Martinos Center for Biomedical Imaging, 13th Street, Charlestown, MA 02129, USA
Neuroimage 23:582-95. 2004
..Spectral spatiotemporal imaging of cortical oscillations and interactions in the human brain can provide further understanding of large-scale neural activity and communication between different brain regions...
- Parallel imaging reconstruction using automatic regularization
Fa Hsuan Lin
Division of Health Sciences and Technology, Harvard Medical School MIT, Cambridge, Massachusetts, USA
Magn Reson Med 51:559-67. 2004
..47 to 0.80 in twofold sensitivity encoding (SENSE) acceleration. In vivo anatomical images from an eight-channel system show an averaged g-factor reduction of 1.22 to 0.84 in 2.67-fold acceleration...
- Degenerate mode birdcage volume coil for sensitivity-encoded imaging
Fa-Hsuan Lin
Havard-MIT Division of Health Sciences and Technology, Boston, Massachusetts 02129, USA
Magn Reson Med 50:1107-11. 2003
..5 T. The maximal 2-fold acceleration in this dual-mode degenerate birdcage coil offers the potential to extend SENSE-type image reconstruction methods to applications demanding uniform whole brain coverage...
- A wavelet-based approximation of surface coil sensitivity profiles for correction of image intensity inhomogeneity and parallel imaging reconstruction
Fa Hsuan Lin
Harvard Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, Massachusetts, USA
Hum Brain Mapp 19:96-111. 2003
..The results, using bi-orthogonal Daubechies 97 wavelets and other members in this family, are evaluated for T1-weighted and T2-weighted brain imaging...
