Chun Yen Lin

Summary

Publications

  1. pmc Low-pressure pulsed focused ultrasound with microbubbles promotes an anticancer immunological response
    Hao Li Liu
    Department of Electrical Engineering, Chang Gung University, Taoyuan, Taiwan
    J Transl Med 10:221. 2012
  2. ncbi request reprint Patients younger than forty years old with hepatitis C virus genotype-1 chronic infection had treatment responses similar to genotype-2 infection and not related to interleukin-28B polymorphism
    Chun Yen Lin
    Division of Hepatology, Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Taiwan
    Ann Hepatol 12:62-9. 2013
  3. ncbi request reprint Various predictors of sustained virologic response in different age groups of patients with genotype-1 chronic hepatitis C
    Chun Yen Lin
    Departments of Gastroenterology and Hepatology Rheumatology, Allergy and Immunology, Linkou Medical Center, Chang Gung Memorial Hospital School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    J Clin Gastroenterol 47:794-9. 2013
  4. pmc IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection
    Chun Yen Lin
    Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
    PLoS ONE 6:e18322. 2011
  5. pmc MELD score can predict early mortality in patients with rebleeding after band ligation for variceal bleeding
    Wei Ting Chen
    Department of Hepato Gastroenterology, Linkou Medical Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 333, Taipei, Taiwan, China
    World J Gastroenterol 17:2120-5. 2011
  6. ncbi request reprint A strong association between down-regulation of HLA-DR expression and the late mortality in patients with severe acute pancreatitis
    Yu Pin Ho
    Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
    Am J Gastroenterol 101:1117-24. 2006
  7. pmc None of the six SNPs of IL28B could predict treatment responses in genotype 2 chronic HCV infected patients by propensity score matching analysis
    Wen Juei Jeng
    Division of Hepatology, Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    PLoS ONE 7:e48217. 2012
  8. doi request reprint Recurrence of spontaneous bacterial peritonitis in cirrhotic patients non-prophylactically treated with norfloxacin: serum albumin as an easy but reliable predictive factor
    Chien Hao Huang
    Department of Hepato Gastroenterology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, ROC
    Liver Int 31:184-91. 2011
  9. doi request reprint Predictors of changes in hemoglobin levels in patients with chronic hepatitis C treated with ribavirin plus pegylated interferon-α
    Ching Chih Hu
    Liver Research Unit, Chang Gung Memorial Hospital, Keelung, Taiwan
    Ren Fail 34:429-34. 2012
  10. doi request reprint Tumor necrosis factor-α and interleukin-10 contribute to immunoparalysis in patients with acute pancreatitis
    Yu Pin Ho
    Department of Hepatogastroenterology, Linkou Medical Center, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Hum Immunol 72:18-23. 2011

Collaborators

Detail Information

Publications19

  1. pmc Low-pressure pulsed focused ultrasound with microbubbles promotes an anticancer immunological response
    Hao Li Liu
    Department of Electrical Engineering, Chang Gung University, Taoyuan, Taiwan
    J Transl Med 10:221. 2012
    ..Here we demonstrated that another form of focused ultrasound delivery, using low-pressure, pulsed-mode exposure in the presence of microbubbles (MBs), may also trigger an antitumor immunological response and inhibit tumor growth...
  2. ncbi request reprint Patients younger than forty years old with hepatitis C virus genotype-1 chronic infection had treatment responses similar to genotype-2 infection and not related to interleukin-28B polymorphism
    Chun Yen Lin
    Division of Hepatology, Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Taiwan
    Ann Hepatol 12:62-9. 2013
    ..However, the treatment responses of the young patients had not been analyzed before. Therefore, we conducted this study to investigate the treatment responses of CHC patients younger than 40 years old (y/o)...
  3. ncbi request reprint Various predictors of sustained virologic response in different age groups of patients with genotype-1 chronic hepatitis C
    Chun Yen Lin
    Departments of Gastroenterology and Hepatology Rheumatology, Allergy and Immunology, Linkou Medical Center, Chang Gung Memorial Hospital School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    J Clin Gastroenterol 47:794-9. 2013
    ..However, variation of SVR predictors in different age groups was not explored before. We therefore conducted this study for investigating this issue...
  4. pmc IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection
    Chun Yen Lin
    Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
    PLoS ONE 6:e18322. 2011
    ..This study was to investigate the predictive power of IL28B SNPs for on-treatment responses and SVR in treatment-naïve patients with GT1-HCV chronic infection...
  5. pmc MELD score can predict early mortality in patients with rebleeding after band ligation for variceal bleeding
    Wei Ting Chen
    Department of Hepato Gastroenterology, Linkou Medical Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan 333, Taipei, Taiwan, China
    World J Gastroenterol 17:2120-5. 2011
    ..To investigate the outcomes, as well as risk factors for 6-wk mortality, in patients with early rebleeding after endoscopic variceal band ligation (EVL) for esophageal variceal hemorrhage (EVH)...
  6. ncbi request reprint A strong association between down-regulation of HLA-DR expression and the late mortality in patients with severe acute pancreatitis
    Yu Pin Ho
    Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan
    Am J Gastroenterol 101:1117-24. 2006
    ..However, the relationship between this parameter and late mortality of acute pancreatitis is still unclear. Therefore, we conducted this study in order to elucidate this issue...
  7. pmc None of the six SNPs of IL28B could predict treatment responses in genotype 2 chronic HCV infected patients by propensity score matching analysis
    Wen Juei Jeng
    Division of Hepatology, Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    PLoS ONE 7:e48217. 2012
    ..This study investigated the predictability of six single nucleotide polymorphisms (SNP) of IL28B on the treatment responses of PR in patients with CHC GT2...
  8. doi request reprint Recurrence of spontaneous bacterial peritonitis in cirrhotic patients non-prophylactically treated with norfloxacin: serum albumin as an easy but reliable predictive factor
    Chien Hao Huang
    Department of Hepato Gastroenterology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan, ROC
    Liver Int 31:184-91. 2011
    ..Nonetheless, there are no definitive patient selection parameters identifying who would benefit from SID...
  9. doi request reprint Predictors of changes in hemoglobin levels in patients with chronic hepatitis C treated with ribavirin plus pegylated interferon-α
    Ching Chih Hu
    Liver Research Unit, Chang Gung Memorial Hospital, Keelung, Taiwan
    Ren Fail 34:429-34. 2012
    ..The aim of this study was to evaluate the magnitude and frequency of change in Hb and determine the predictive risk factors for Hb decrease during this therapy...
  10. doi request reprint Tumor necrosis factor-α and interleukin-10 contribute to immunoparalysis in patients with acute pancreatitis
    Yu Pin Ho
    Department of Hepatogastroenterology, Linkou Medical Center, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Hum Immunol 72:18-23. 2011
    ..Therefore, both TNF-α and IL-10 contributed to the development of immunoparalysis in patients with acute pancreatitis...
  11. doi request reprint LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer
    Jayashri Mahalingam
    Department of Gastroenterology Hepatology, Chang Gung University, Kweishan, Tayouan, Taiwan
    Clin Cancer Res 18:5224-33. 2012
    ..LAP(+)CD4(+) T cell is a recently identified subset of suppressor T cells. This study was designed to investigate their clinical relevance in patients with CRC...
  12. doi request reprint Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer
    Yung Chang Lin
    Department of Hematology Oncology, Linkou Medical Center, Chang Gung Memorial Hospital, Kweishan, Tayouan, Taiwan
    Int J Cancer 132:1341-50. 2013
    ..In summary, we confirmed that activated T(reg) cells are a distinct subgroup with effector memory phenotype and fully functional regulatory activity against human colorectal cancer immunity...
  13. ncbi request reprint Expression of the HCRP1 mRNA in HCC as an independent predictor of disease-free survival after surgical resection
    Ming Wei Lai
    Department of Pediatric Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Hepatol Res 39:164-76. 2009
    ..852; 95% CI, 1.131-3.032; P = 0.014) were included as independent predictors for disease-free survival. Conclusion: Expression of HCRP1 mRNA served as an independent predictor for postoperative disease-free survival in HCC patients...
  14. doi request reprint Oral inoculation of probiotics Lactobacillus acidophilus NCFM suppresses tumour growth both in segmental orthotopic colon cancer and extra-intestinal tissue
    Chien Chang Chen
    Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Chang Gung Children s Hospital, 12L, 5 Fu Hsing Street, Kwei Shan, Taoyuan 333, Taiwan, ROC
    Br J Nutr 107:1623-34. 2012
    ..The down-regulated expression of CXCR4 mRNA and MHC class I, as well as increasing apoptosis in tumour tissue, indicated that La may be associated with modulating the cellular response triggered by colon carcinogenesis...
  15. ncbi request reprint EMR2 receptor ligation modulates cytokine secretion profiles and cell survival of lipopolysaccharide-treated neutrophils
    Tzu Ying Chen
    Department of Microbiology and Immunology, College of Medicine, Chang Gung University, Taoyuan, Taiwan
    Chang Gung Med J 34:468-77. 2011
    ..In this study, we examined the effect of EMR2 ligation by its specific antibody on the cytokine expression profile and cell survival of lipopolysaccharide (LPS)-treated neutrophils...
  16. doi request reprint Hepatitis B virus-DNA level and basal core promoter A1762T/G1764A mutation in liver tissue independently predict postoperative survival in hepatocellular carcinoma
    Chau Ting Yeh
    Liver Research Center, Department of Hepato Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Hepatology 52:1922-33. 2010
    ..A short stretch pre-S deletion located between codons 107 and 141 was strongly associated with a poorer postoperative prognosis...
  17. pmc Vascularized composite allograft rejection is delayed by intrajejunal treatment with donor splenocytes without concomitant immunosuppressants
    Christopher Glenn Wallace
    Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University and Medical College, Taipei, Taiwan
    Clin Dev Immunol 2012:704063. 2012
    ..We studied its effects on recipient immune responses and VCA rejection...
  18. ncbi request reprint Endotoxemia contributes to the immune paralysis in patients with cirrhosis
    Chun Yen Lin
    Department of Hepatogastroenterology, Linkou Medical Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan
    J Hepatol 46:816-26. 2007
    ..However, the relationship between HLA-DR expression and cirrhosis is unclear...
  19. doi request reprint The indispensable role of CCR5 for in vivo suppressor function of tumor-derived CD103+ effector/memory regulatory T cells
    Li Yuan Chang
    College of Medicine, Chang Gung University, Kweishan, Taoyuan, Taiwan
    J Immunol 189:567-74. 2012
    ..In conclusion, these results indicate that the potent in vivo suppression ability of CD103(+) Tregs is due to the tissue-migration ability through CCR5 expression...