Ajit P Limaye

Summary

Publications

  1. pmc CMV in critically ill patients: pathogen or bystander?
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington and Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Rev Med Virol 20:372-9. 2010
  2. ncbi request reprint Impact of cytomegalovirus in organ transplant recipients in the era of antiviral prophylaxis
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98195 7110, USA
    Transplantation 81:1645-52. 2006
  3. pmc Cytomegalovirus reactivation in critically ill immunocompetent patients
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195 7110, USA
    JAMA 300:413-22. 2008
  4. pmc Quantitation of cytomegalovirus DNA load in dried blood spots correlates well with plasma viral load
    Ajit P Limaye
    Department of Medicine, University of Washington, Washington, USA
    J Clin Microbiol 51:2360-4. 2013
  5. ncbi request reprint Incidence and clinical features of ganciclovir-resistant cytomegalovirus disease in heart transplant recipients
    Fanny Li
    Department of Pharmacy Services, University of Washington, Seattle, WA 98195, USA
    Clin Infect Dis 45:439-47. 2007
  6. pmc Marked variability of BK virus load measurement using quantitative real-time PCR among commonly used assays
    Noah G Hoffman
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington 98195, USA
    J Clin Microbiol 46:2671-80. 2008
  7. ncbi request reprint Antiviral resistance in cytomegalovirus: an emerging problem in organ transplant recipients
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, WA 98195, USA
    Semin Respir Infect 17:265-73. 2002
  8. pmc Rapid detection of human cytomegalovirus UL97 and UL54 mutations directly from patient samples
    Ruth Hall Sedlak
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA
    J Clin Microbiol 51:2354-9. 2013
  9. doi request reprint Infections in transplant patients
    Genevieve L Pagalilauan
    Division of General Internal Medicine, University of Washington School of Medicine, 4245 Roosevelt Way Northeast, Seattle, WA 98115, USA
    Med Clin North Am 97:581-600, x. 2013
  10. pmc Convenient selective differential broth for isolation of vancomycin-resistant enterococcus from fecal material
    Thomas J Novicki
    Department of Laboratory Medicine, University of Washington, Seattle, Washington 98195 7110, USA
    J Clin Microbiol 42:1637-40. 2004

Collaborators

Detail Information

Publications27

  1. pmc CMV in critically ill patients: pathogen or bystander?
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington and Program in Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Rev Med Virol 20:372-9. 2010
    ....
  2. ncbi request reprint Impact of cytomegalovirus in organ transplant recipients in the era of antiviral prophylaxis
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington, Seattle, WA 98195 7110, USA
    Transplantation 81:1645-52. 2006
    ..Antiviral prophylaxis has been shown to decrease the incidence of cytomegalovirus (CMV) disease in organ transplant recipients, but whether CMV disease that occurs despite prophylaxis is associated with mortality remains unknown...
  3. pmc Cytomegalovirus reactivation in critically ill immunocompetent patients
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington Medical Center, 1959 NE Pacific St, Seattle, WA 98195 7110, USA
    JAMA 300:413-22. 2008
    ....
  4. pmc Quantitation of cytomegalovirus DNA load in dried blood spots correlates well with plasma viral load
    Ajit P Limaye
    Department of Medicine, University of Washington, Washington, USA
    J Clin Microbiol 51:2360-4. 2013
    ..Future studies to optimize and evaluate this methodology for patient self-collected samples are warranted...
  5. ncbi request reprint Incidence and clinical features of ganciclovir-resistant cytomegalovirus disease in heart transplant recipients
    Fanny Li
    Department of Pharmacy Services, University of Washington, Seattle, WA 98195, USA
    Clin Infect Dis 45:439-47. 2007
    ..The incidence and clinical and virologic aspects of ganciclovir-resistant cytomegalovirus (CMV) disease have not been well-characterized in heart transplant recipients...
  6. pmc Marked variability of BK virus load measurement using quantitative real-time PCR among commonly used assays
    Noah G Hoffman
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington 98195, USA
    J Clin Microbiol 46:2671-80. 2008
    ..These results suggest that both accurate BKV measurement and the uniform application of BKV screening guidelines could be significantly improved by the use of standardized reference materials and PCR primers and probes...
  7. ncbi request reprint Antiviral resistance in cytomegalovirus: an emerging problem in organ transplant recipients
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, WA 98195, USA
    Semin Respir Infect 17:265-73. 2002
    ..Better diagnostic tools and newer, less toxic, antiviral agents with different mechanisms of action are urgently needed to decrease the morbidity associated with this complication in organ transplant recipients...
  8. pmc Rapid detection of human cytomegalovirus UL97 and UL54 mutations directly from patient samples
    Ruth Hall Sedlak
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, USA
    J Clin Microbiol 51:2354-9. 2013
    ..One of these patients had no concurrent UL97 mutation, pointing toward the need for an assay that facilitates dual UL97/UL54 gene testing for complete resistance profiling...
  9. doi request reprint Infections in transplant patients
    Genevieve L Pagalilauan
    Division of General Internal Medicine, University of Washington School of Medicine, 4245 Roosevelt Way Northeast, Seattle, WA 98115, USA
    Med Clin North Am 97:581-600, x. 2013
    ..General concepts are reviewed, and a series of patient cases described that illustrate the specific learning points based on common presenting clinical symptoms. ..
  10. pmc Convenient selective differential broth for isolation of vancomycin-resistant enterococcus from fecal material
    Thomas J Novicki
    Department of Laboratory Medicine, University of Washington, Seattle, Washington 98195 7110, USA
    J Clin Microbiol 42:1637-40. 2004
    ..We have thus developed an easily prepared vancomycin selective differential broth that is significantly more sensitive and specific in the detection of VRE than is direct fecal plating to BEA agar...
  11. ncbi request reprint Late-onset cytomegalovirus disease in liver transplant recipients despite antiviral prophylaxis
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Transplantation 78:1390-6. 2004
    ..The incidence and impact of cytomegalovirus (CMV) disease that occurs despite CMV prophylaxis among liver transplant recipients have been incompletely defined...
  12. ncbi request reprint Ganciclovir-resistant cytomegalovirus in organ transplant recipients
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, WA 98195 7110, USA
    Clin Infect Dis 35:866-72. 2002
    ..Better diagnostic tools and newer, less-toxic antiviral agents with different mechanisms of action are urgently needed to decrease the morbidity associated with this complication in organ transplant recipients...
  13. ncbi request reprint Polyomavirus nephropathy in native kidneys of non-renal transplant recipients
    Ajit P Limaye
    Departments of Laboratory Medicine and Medicine, University of Washington, Seattle, WA, USA
    Am J Transplant 5:614-20. 2005
    ..Studies to define the incidence and potential contribution of PVN to chronic renal dysfunction commonly attributed to calcineurin inhibitor toxicity in non-renal transplant recipients are warranted...
  14. ncbi request reprint High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy
    Ajit P Limaye
    Department of Laboratory Medicine, University of Washington, Seattle, WA, USA
    J Infect Dis 185:20-7. 2002
    ..All ganR isolates contained a UL97 mutation. GanR CMV infection occurs in nearly 10% of lung transplant recipients, despite preemptive antiviral therapy, and is more common among D+/R- patients...
  15. ncbi request reprint Invasive pneumococcal infections in adult lung transplant recipients
    Guy de Bruyn
    Department of Medicine, University of Washington, Washington, WA, USA
    Am J Transplant 4:1366-71. 2004
    ..Alternative prevention strategies, including use of the conjugated pneumococcal vaccine, should be explored in future studies...
  16. doi request reprint Systematic assessment of culture review as a tool to assess errors in the clinical microbiology laboratory
    Nancy Goodyear
    Department of Laboratory Medicine, University of Washington, Box 357110, Seattle, WA 98195, USA
    Arch Pathol Lab Med 132:1792-5. 2008
    ..Daily supervisory review is a common practice in microbiology laboratories; however, there are no publications describing errors corrected by this practice...
  17. ncbi request reprint Association of hepatic iron overload with invasive fungal infection in liver transplant recipients
    Jacob Alexander
    Division of Gastroenterology, University of Washington Medical Center, Seattle, WA 98195, USA
    Liver Transpl 12:1799-804. 2006
    ..45-6.56; P = 0.003). Hepatic iron overload is strongly and independently associated with posttransplantation invasive fungal infections. Studies to confirm this finding in other centers and define the mechanism are warranted...
  18. pmc Isolation of metronidazole-resistant Bacteroides fragilis carrying the nimA nitroreductase gene from a patient in Washington State
    Jeffrey M Schapiro
    Department of Laboratory Medicine, University of Washington Medical Center, Box 357110, 1959 NE Pacific St, Seattle, WA 98195, USA
    J Clin Microbiol 42:4127-9. 2004
    ..fragilis strains in the United States and the importance of susceptibility testing in selected situations...
  19. pmc Strongyloidiasis in transplant patients
    Alison C Roxby
    Division of Allergy and Infectious Diseases, University of Washington, Seattle, USA
    Clin Infect Dis 49:1411-23. 2009
    ....
  20. pmc Prosthetic joint infection due to "Helcococcus pyogenes" [corrected]
    Anil A Panackal
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA 98195 7110, USA
    J Clin Microbiol 42:2872-4. 2004
    ..We describe a case of prosthetic joint infection due to a previously undescribed organism that is genetically most closely related to Helcococcus...
  21. pmc Rapid identification of commonly encountered Candida species directly from blood culture bottles
    Rangaraj Selvarangan
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington 98195 7110, USA
    J Clin Microbiol 41:5660-4. 2003
    ..Our assay allows rapid (</=2 h) and specific detection of the most common Candida spp. directly from positive blood cultures and may facilitate delivery of optimal antifungal therapy...
  22. doi request reprint Short-course isoniazid plus rifapentine directly observed therapy for latent tuberculosis in solid-organ transplant candidates
    Diego Lopez de Castilla
    1 Solid Organ Transplant Infectious Disease Program, Division of Allergy and Infectious Disease, Department of Medicine, University of Washington, Seattle, WA 2 TB Control Program, Public Health Seattle and King County, WA 3 Division of Pulmonary and Critical Care, Department of Medicine, University of Washington, Seattle, WA 4 School of Pharmacy, University of Washington, Seattle, WA 5 Address correspondence to Ajit P Limaye, M D, University of Washington, Box 356174, 1959 NE Pacific St, Seattle, WA 98195 6174
    Transplantation 97:206-11. 2014
    ....
  23. pmc Clinical impact associated with corrected results in clinical microbiology testing
    Shan Yuan
    Department of Laboratory Medicine, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195 7110, USA
    J Clin Microbiol 43:2188-93. 2005
    ..Our method has the potential to be implemented in other laboratory settings to identify and characterize errors that impact patient safety...
  24. ncbi request reprint Polyomavirus nephropathy in pediatric kidney transplant recipients
    Jodi M Smith
    Department of Pediatrics, Division of Nephrology, University of Washington, Seattle, WA, USA
    Am J Transplant 4:2109-17. 2004
    ..Further studies to confirm this finding and to define the clinical utility of routine pre-transplant BKV serologic testing are warranted...
  25. pmc Nocardia veterana, a new emerging pathogen
    Sudha Pottumarthy
    Department of Laboratory Medicine, University of Washington, Seattle, Washington 98195, USA
    J Clin Microbiol 41:1705-9. 2003
    ..These cases illustrate the pathogenic potential of this newly described species and emphasize the importance of accurate identification of Nocardia isolates to the species level by integrated use of phenotypic and genotypic methods...
  26. ncbi request reprint Inconsistent localization of gram-positive bacteria to prostate-specific specimens from patients with chronic prostatitis
    John N Krieger
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 66:721-5. 2005
    ..To determine the rate of gram-positive localizations and whether repetitive cultures demonstrate consistent localization of gram-positive bacteria in patients with chronic prostatitis symptoms...
  27. ncbi request reprint Confirmation of Chagas' cardiomyopathy following heart transplantation
    Binh An P Phan
    Division of Cardiology, Department of Medicine, University of Washington, 1914 N 34th Street, Suite 105, Seattle, WA 98103, USA
    Heart Vessels 21:325-7. 2006
    ..We review the epidemiology, cardiac pathology, and evaluation of patients with Chagas' cardiac disease. We discuss the clinical features of Chagas' cardiomyopathy and available treatments including cardiac transplantation...