- Genotoxicity of the steroidal oestrogens oestrone and oestradiol: possible mechanism of uterine and mammary cancer developmentJ G Liehr
Stehlin Foundation for Cancer Research at Christus St Joseph Hospital, Houston, Texas 77003, USA
Hum Reprod Update 7:273-81. 2001..Sequencing of this gene isolated from V79 mutant clones revealed point mutations and deletions. It is concluded that oestradiol plays a dual role as mutagen/carcinogen and as growth-stimulating hormone in the induction of tumours...
- Role of iron in estrogen-induced cancerJ G Liehr
Stehlin Foundation for Cancer Research, 1918 Chenevert, Houston, TX 77003, USA
Curr Med Chem 8:839-49. 2001..A role of iron in hormone-associated cancer in humans offers attractive routes for cancer prevention by regulating metal ion metabolism and interfering with iron accumulation in tissues...
- IRON AND ESTROGEN INDUCED CARCINOGENESISJOACHIM LIEHR; Fiscal Year: 2001..In future experiments he will extend his findings to understanding the interactions of vitamins A and D with estrogens and iron in the etiology of breast cancer, and extend his hypothesis to prostate cancer. ..