Shang Dong Liang

Summary

Publications

  1. Zou L, Gong Y, Liu S, Liang S. Natural compounds acting at P2 receptors alleviate peripheral neuropathy. Brain Res Bull. 2018;: pubmed publisher
  2. Yuan H, Ouyang S, Yang R, Li S, Gong Y, Zou L, et al. Osthole alleviated diabetic neuropathic pain mediated by the P2X4 receptor in dorsal root ganglia. Brain Res Bull. 2018;142:289-296 pubmed publisher
    ..Thus, osthole treatment may act on the P2X4 receptor to alleviate the mechanical and thermal hyperalgesia in DM rats. ..
  3. Li X, Kang L, Li G, Zeng H, Zhang L, Ling X, et al. Intrathecal leptin inhibits expression of the P2X2/3 receptors and alleviates neuropathic pain induced by chronic constriction sciatic nerve injury. Mol Pain. 2013;9:65 pubmed publisher
    ..Our findings suggest that exogenous leptin can alleviate the chronic neuropathic pain caused by CCI. The leptin effect may be mediated by attenuated expression of IL-6, TNF?, and the P2X2 and P2X3 receptors in the DRG of CCI rats. ..
  4. Wu H, Nie Y, Xiong H, Liu S, Li G, Huang A, et al. P2X7 Receptor Expression in Peripheral Blood Monocytes Is Correlated With Plasma C-Reactive Protein and Cytokine Levels in Patients With Type 2 Diabetes Mellitus: a Preliminary Report. Inflammation. 2015;38:2076-81 pubmed publisher
    ..These findings indicated that P2X7 receptor in peripheral blood monocytes may be involved in the pathological changes of T2DM, particularly affecting patients with high CRP levels. ..
  5. Lv Q, Xue Y, Li G, Zou L, Zhang X, Ying M, et al. Beneficial effects of evodiamine on P2X(4)-mediated inflammatory injury of human umbilical vein endothelial cells due to high glucose. Int Immunopharmacol. 2015;28:1044-9 pubmed publisher
    ..Thus the evodiamine may exert the anti-inflammation activity on high-glucose challenge HUVEC via suppressing the P2X4R signaling pathway, exhibiting beneficial ability to protect HUVECs from glucotoxicity. ..
  6. Zou L, Tu G, Xie W, Wen S, Xie Q, Liu S, et al. LncRNA NONRATT021972 involved the pathophysiologic processes mediated by P2X7 receptors in stellate ganglia after myocardial ischemic injury. Purinergic Signal. 2016;12:127-37 pubmed publisher
    ..NONRATT021972 siRNA treatment prevented the pathophysiologic processes mediated by P2X7 receptors in the SG after myocardial ischemic injury. ..
  7. Wang S, Xu H, Zou L, Xie J, Wu H, Wu B, et al. LncRNA uc.48+ is involved in diabetic neuropathic pain mediated by the P2X3 receptor in the dorsal root ganglia. Purinergic Signal. 2016;12:139-48 pubmed publisher
    ..48+ siRNA treatment. Therefore, uc.48+ siRNA treatment may alleviate the DNP by inhibiting the excitatory transmission mediated by the P2X3 receptor in DRG. ..
  8. Zhang J, Liu S, Xu B, Li G, Li G, Huang A, et al. Study of baicalin on sympathoexcitation induced by myocardial ischemia via P2X3 receptor in superior cervical ganglia. Auton Neurosci. 2015;189:8-15 pubmed publisher
    ..Baicalin might decrease sympathetic activity via inhibiting P2X3 receptor in rat SCG to protect the myocardium. ..
  9. Guo L, Li L, Liu M, Wan Q, Tian J, Huang Q, et al. Bottom-up preparation of nitrogen doped carbon quantum dots with green emission under microwave-assisted hydrothermal treatment and their biological imaging. Mater Sci Eng C Mater Biol Appl. 2018;84:60-66 pubmed publisher
    ..Owing to the facile experimental procedure and outstanding features of CDs, this work will open up a new avenue for fabrication and biomedical applications of CDs. ..

More Information

Publications29

  1. Lv Q, Wang K, Xu D, Liu M, Wan Q, Huang H, et al. Synthesis of Amphiphilic Hyperbranched AIE-active Fluorescent Organic Nanoparticles and Their Application in Biological Application. Macromol Biosci. 2016;16:223-30 pubmed publisher
  2. Liu S, Zou L, Xie J, Xie W, Wen S, Xie Q, et al. LncRNA NONRATT021972 siRNA regulates neuropathic pain behaviors in type 2 diabetic rats through the P2X7 receptor in dorsal root ganglia. Mol Brain. 2016;9:44 pubmed publisher
    ..Moreover, NONRATT021972 siRNA treatment reduced the release of inflammatory factors (TNF-?), thereby inhibiting the excitability of DRG neurons and reducing mechanical and thermal hyperalgesia in type 2 DM rats. ..
  3. Xu H, He L, Liu C, Tang L, Xu Y, Xiong M, et al. LncRNA NONRATT021972 siRNA attenuates P2X7 receptor expression and inflammatory cytokine production induced by combined high glucose and free fatty acids in PC12 cells. Purinergic Signal. 2016;12:259-68 pubmed publisher
    ..Therefore, inhibition of nc021972 may serve as a novel therapeutic strategy for diabetes complicated with nervous inflammatory diseases. ..
  4. Ying M, Liu H, Zhang T, Jiang C, Gong Y, Wu B, et al. Effect of artemisinin on neuropathic pain mediated by P2X4 receptor in dorsal root ganglia. Neurochem Int. 2017;108:27-33 pubmed publisher
    ..This finding suggested that artemisinin could inhibit the nociceptive transmission mediated by P2X4 receptor in the DRG SGCs and thus relieve pain behaviors in the CCI rats. ..
  5. Rao S, Liu S, Zou L, Jia T, Zhao S, Wu B, et al. The effect of sinomenine in diabetic neuropathic pain mediated by the P2X3 receptor in dorsal root ganglia. Purinergic Signal. 2017;13:227-235 pubmed publisher
    ..Therefore, sinomenine treatment may suppress the up-regulated expression and activation of the P2X3 receptor and relieve the hyperalgesia potentiated by the activation of P38MAPK in T2DM rats. ..
  6. request reprint
    Hong W, Li G, Nie Y, Zou L, Zhang X, Liu S, et al. Potential Involvement of P2 Receptors in the Pathological Processes of Hyperthyroidism: A Pilot Study. Ann Clin Lab Sci. 2016;46:254-9 pubmed
    ..In a conclusion, there is a relationship between the elevated expression of P2X3 receptor and P2X7 receptor in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients. ..
  7. Wu B, Zhang C, Zou L, Ma Y, Huang K, Lv Q, et al. LncRNA uc.48+ siRNA improved diabetic sympathetic neuropathy in type 2 diabetic rats mediated by P2X7 receptor in SCG. Auton Neurosci. 2016;197:14-8 pubmed publisher
    ..In conclusion, lncRNA uc.48+ siRNA improved diabetic sympathetic neuropathy in type 2 diabetic rats through regulating the expression of P2X7 and ERK signaling in SCG. ..
  8. Li G, Zou L, Xie W, Wen S, Xie Q, Gao Y, et al. The effects of NONRATT021972 lncRNA siRNA on PC12 neuronal injury mediated by P2X7 receptor after exposure to oxygen-glucose deprivation. Purinergic Signal. 2016;12:479-87 pubmed publisher
    ..Therefore, treatment with NONRATT021972 siRNA may decrease sympathetic neuronal injury induced by ischemia. ..
  9. Xu H, Liu C, Rao S, He L, Zhang T, Sun S, et al. LncRNA NONRATT021972 siRNA rescued decreased heart rate variability in diabetic rats in superior cervical ganglia. Auton Neurosci. 2016;201:1-7 pubmed publisher
    ..Meanwhile, NONRATT021972 siRNA rescued decreased HRV in DM rats. Therefore, inhibition of NONRATT021972 may serve as a novel therapeutic strategy for preventing the development of DCAN. ..
  10. Xie J, Liu S, Wu B, Li G, Rao S, Zou L, et al. The protective effect of resveratrol in the transmission of neuropathic pain mediated by the P2X7 receptor in the dorsal root ganglia. Neurochem Int. 2017;103:24-35 pubmed publisher
    ..Our data provide evidence that RES may suppress the transmission of neuropathic pain mediated by the P2X7 receptor in the satellite glial cells of dorsal root ganglia. ..
  11. Yi Z, Rao S, Ouyang S, Bai Y, Yang J, Ma Y, et al. A317491 relieved HIV gp120-associated neuropathic pain involved in P2X3 receptor in dorsal root ganglia. Brain Res Bull. 2017;130:81-89 pubmed publisher
    ..Therefore, the inhibition of the P2X3 receptor in rat DRG neurons relieved gp120-induced mechanical hyperalgesia. ..
  12. Peng H, Zou L, Xie J, Wu H, Wu B, Zhu G, et al. lncRNA NONRATT021972 siRNA Decreases Diabetic Neuropathic Pain Mediated by the P2X3 Receptor in Dorsal Root Ganglia. Mol Neurobiol. 2017;54:511-523 pubmed publisher
    ..Thus, NONRATT021972 siRNA treatment may suppress the upregulated expression and activation of the P2X3 receptor and reduce the hyperalgesia potentiated by the pro-inflammatory cytokine TNF-α in T2DM rats. ..
  13. Tu G, Zou L, Liu S, Wu B, Lv Q, Wang S, et al. Long noncoding NONRATT021972 siRNA normalized abnormal sympathetic activity mediated by the upregulation of P2X7 receptor in superior cervical ganglia after myocardial ischemia. Purinergic Signal. 2016;12:521-35 pubmed publisher
    ..Our findings suggest that NONRATT021972 siRNA could decrease the upregulation of the P2X7 receptor and improve the abnormal changes in cardiac function after myocardial ischemia. ..
  14. Xiong W, Tan M, He L, Ou X, Jin Y, Yang G, et al. Inhibitory effects of tetramethylpyrazine on pain transmission of trigeminal neuralgia in CCI-ION rats. Brain Res Bull. 2017;134:72-78 pubmed publisher
    ..Thus, TMP might have inhibitory effects on trigeminal neuralgia by suppressing the expression of P2X3 receptor in the TG and the phosphorylation of p38 and ERK1/2 in the TG. ..
  15. Xu H, Gong C, He L, Rao S, Liu X, Nie Y, et al. Purinergic P2X7 receptor functional genetic polymorphisms are associated with the susceptibility to osteoporosis in Chinese postmenopausal women. Purinergic Signal. 2017;13:339-346 pubmed publisher
    ..The findings suggest that the P2X7R rs3751143 functional polymorphism might contribute to OP susceptibility in Chinese postmenopausal women. ..
  16. Shi L, Wu B, Yi Z, Zhao S, Zou L, Li L, et al. P2Y12 shRNA treatment relieved HIV gp120-induced neuropathic pain in rats. Neurochem Int. 2018;112:259-266 pubmed publisher
    ..Upregulation of GFAP is a marker of SGC activation. Therefore, P2Y12 shRNA treatment decreased HIV gp120-induced mechanical and thermal hyperalgesia in gp120-treated rats. ..
  17. Li L, Sheng X, Zhao S, Zou L, Han X, Gong Y, et al. Nanoparticle-encapsulated emodin decreases diabetic neuropathic pain probably via a mechanism involving P2X3 receptor in the dorsal root ganglia. Purinergic Signal. 2017;13:559-568 pubmed publisher
    ..Therefore, nano emodin treatment may relieve DNP by decreasing excitatory transmission mediated by the DRG P2X3 receptor in T2DM rats. ..
  18. Wu B, Peng L, Xie J, Zou L, Zhu Q, Jiang H, et al. The P2X7 receptor in dorsal root ganglia is involved in HIV gp120-associated neuropathic pain. Brain Res Bull. 2017;135:25-32 pubmed publisher
    ..Therefore, inhibition of the P2X7 receptor in rat DRG relieved gp120-induced mechanical hyperalgesia and thermal hyperalgesia. ..
  19. Zhao S, Yang J, Han X, Gong Y, Rao S, Wu B, et al. Effects of nanoparticle-encapsulated curcumin on HIV-gp120-associated neuropathic pain induced by the P2X3 receptor in dorsal root ganglia. Brain Res Bull. 2017;135:53-61 pubmed publisher
    ..Therefore, nano curcumin treatment may inhibit P2X3 activation, decrease the sensitizing DRG primary afferents and relieve mechanical hyperalgesia and thermal hyperalgesia in gp120-treated rats. ..
  20. Yi Z, Xie L, Zhou C, Yuan H, Ouyang S, Fang Z, et al. P2Y12 receptor upregulation in satellite glial cells is involved in neuropathic pain induced by HIV glycoprotein 120 and 2',3'-dideoxycytidine. Purinergic Signal. 2018;14:47-58 pubmed publisher
    ..Thus, downregulating the P2Y12 receptor relieved mechanical and thermal hyperalgesia in gp120+ddC-treated rats. ..