Zongjin Li

Summary

Publications

  1. pmc Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases
    Zongjin Li
    The Department of Radiology and Molecular Imaging Program at Stanford MIPS, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cell Biochem 106:194-9. 2009
  2. pmc Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction
    Zongjin Li
    Department of Radiology and Molecular Imaging Program at Stanford MIPS, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 4:e8443. 2009
  3. pmc MicroRNA-210 as a novel therapy for treatment of ischemic heart disease
    Shijun Hu
    Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305 5111, USA
    Circulation 122:S124-31. 2010
  4. pmc Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells
    Zongjin Li
    Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305 5344, USA
    Stem Cells Dev 20:1701-10. 2011
  5. pmc Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion
    Ngan F Huang
    Division of Cardiovascular Medicine, Stanford University, 300 Pasteur Drive, Stanford, CA 94305 5406, USA
    Arterioscler Thromb Vasc Biol 30:984-91. 2010
  6. pmc Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation
    Shijun Hu
    Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305 5454, USA
    Circulation 124:S27-34. 2011
  7. pmc Novel minicircle vector for gene therapy in murine myocardial infarction
    Mei Huang
    Department of Radiology, Stanford University School of Medicine, CA 94305 5344, USA
    Circulation 120:S230-7. 2009
  8. ncbi request reprint Imaging neural stem cell graft-induced structural repair in stroke
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center and Stanford Institute for Neuro Innovationand Translational Neurosciences, Stanford, CA, USA
    Cell Transplant 22:881-92. 2013
  9. pmc Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation
    Xiaoyan Xie
    Department of Radiology and Molecular Imaging Program, Division of Cardiology, Stanford University, Stanford, California 94305 5344, USA
    Stem Cells Dev 18:205-14. 2009
  10. pmc Effects of long-term culture on human embryonic stem cell aging
    Xiaoyan Xie
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Stem Cells Dev 20:127-38. 2011

Collaborators

Detail Information

Publications22

  1. pmc Transplantation of human embryonic stem cell-derived endothelial cells for vascular diseases
    Zongjin Li
    The Department of Radiology and Molecular Imaging Program at Stanford MIPS, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cell Biochem 106:194-9. 2009
    ..Finally, cell enhancement strategies to improve the engraftment efficiency of hESC-ECs will be discussed...
  2. pmc Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction
    Zongjin Li
    Department of Radiology and Molecular Imaging Program at Stanford MIPS, Stanford University School of Medicine, Stanford, California, USA
    PLoS ONE 4:e8443. 2009
    ..Moreover, to fully understand the beneficial effects of stem cell therapy, investigators must be able to track the functional biology and physiology of transplanted cells in living subjects over time...
  3. pmc MicroRNA-210 as a novel therapy for treatment of ischemic heart disease
    Shijun Hu
    Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305 5111, USA
    Circulation 122:S124-31. 2010
    ..We hypothesize that microRNA-210 can rescue cardiac function after myocardial infarction by upregulation of angiogenesis and inhibition of cellular apoptosis in the heart...
  4. pmc Functional characterization and expression profiling of human induced pluripotent stem cell- and embryonic stem cell-derived endothelial cells
    Zongjin Li
    Division of Cardiology, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305 5344, USA
    Stem Cells Dev 20:1701-10. 2011
    ....
  5. pmc Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion
    Ngan F Huang
    Division of Cardiovascular Medicine, Stanford University, 300 Pasteur Drive, Stanford, CA 94305 5406, USA
    Arterioscler Thromb Vasc Biol 30:984-91. 2010
    ..We examined the effect of delivery modality on the survival, localization, and functional effects of exogenously administered embryonic stem cells (ESCs) or endothelial cells derived from them (ESC-ECs) in the ischemic hindlimb...
  6. pmc Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation
    Shijun Hu
    Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305 5454, USA
    Circulation 124:S27-34. 2011
    ..Therefore, the development of novel prosurvival strategies to boost stem cell survival will be of significant benefit to this field...
  7. pmc Novel minicircle vector for gene therapy in murine myocardial infarction
    Mei Huang
    Department of Radiology, Stanford University School of Medicine, CA 94305 5344, USA
    Circulation 120:S230-7. 2009
    ..In this study, we develop a novel nonviral vector that robustly and persistently expresses the hypoxia-inducible factor-1 alpha (HIF-1alpha) therapeutic gene in the heart, leading to functional benefits after myocardial infarction...
  8. ncbi request reprint Imaging neural stem cell graft-induced structural repair in stroke
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center and Stanford Institute for Neuro Innovationand Translational Neurosciences, Stanford, CA, USA
    Cell Transplant 22:881-92. 2013
    ..Longitudinal multimodal imaging provides insights into time course dose-dependent interactions between NSC grafts and structural changes in infarcted tissue...
  9. pmc Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation
    Xiaoyan Xie
    Department of Radiology and Molecular Imaging Program, Division of Cardiology, Stanford University, Stanford, California 94305 5344, USA
    Stem Cells Dev 18:205-14. 2009
    ..This genetically modified line can be used to study the biological role of STAT3 during ES cell differentiation into different derivatives...
  10. pmc Effects of long-term culture on human embryonic stem cell aging
    Xiaoyan Xie
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Stem Cells Dev 20:127-38. 2011
    ..These findings suggest that prolonged culture of hES cells may negatively impact mitochondrial function and possibly affect long-term pluripotency...
  11. pmc Imaging survival and function of transplanted cardiac resident stem cells
    Zongjin Li
    Department of Radiology and Molecular Imaging Program MIPS, Stanford University School of Medicine, Stanford, California 94305 5344, USA
    J Am Coll Cardiol 53:1229-40. 2009
    ..The goal of this study is to characterize resident cardiac stem cells (CSCs) and investigate their therapeutic efficacy in myocardial infarction by molecular imaging methods...
  12. pmc Short hairpin RNA interference therapy for ischemic heart disease
    Mei Huang
    Stanford University School of Medicine, Edwards Building R354, Stanford, CA 94305 5344, USA
    Circulation 118:S226-33. 2008
    ..Here we hypothesize that short hairpin RNA (shRNA) interference therapy targeting PHD2 can be used for treatment of myocardial ischemia and this process can be followed noninvasively by molecular imaging...
  13. pmc Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects
    Zongjin Li
    Department of Radiology and Molecular Imaging Program at Stanford, Stanford University School of Medicine, Stanford, California 94305 5344, USA
    Stem Cells 26:864-73. 2008
    ..Furthermore, transplantation of predifferentiated rather than undifferentiated hES cells would be more suited for avoiding teratoma formation...
  14. pmc A nonviral minicircle vector for deriving human iPS cells
    Fangjun Jia
    Departments of Medicine and Radiology, Stanford University School of Medicine, Stanford, California, USA
    Nat Methods 7:197-9. 2010
    ..Here we use a single minicircle vector to generate transgene-free iPSCs from adult human adipose stem cells...
  15. pmc Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia
    Ian Y Chen
    1 Departments of Radiology, Bioengineering, and Material Science and Engineering, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305
    Hum Gene Ther Methods 24:279-88. 2013
    ..The imaging techniques developed herein should be useful for further optimizing HIF-1α-VP2 therapy in preclinical models of myocardial ischemia...
  16. pmc Effects of ionizing radiation on self-renewal and pluripotency of human embryonic stem cells
    Kitchener D Wilson
    Department of Bioengineering, Stanford University, Stanford, California, USA
    Cancer Res 70:5539-48. 2010
    ..Studies such as this will help define the limits for radiation exposure for pregnant women and also radiotracer reporter probes for tracking cellular regenerative therapies...
  17. pmc Genetic modification of embryonic stem cells with VEGF enhances cell survival and improves cardiac function
    Xiaoyan Xie
    The Department of Radiology and Molecular Imaging Program at Stanford, Stanford University, Stanford, California, USA
    Cloning Stem Cells 9:549-63. 2007
    ..With further validation, this platform may have broad applications for current basic research and further clinical studies...
  18. doi request reprint Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, Stanford, Calif 94305 5487, USA
    Stroke 41:516-23. 2010
    ..In the present study, we sought to investigate the efficacy of human neural stem cells derived from human embryonic stem cells in a rat model of neonatal HI and the mechanisms enhancing brain repair...
  19. pmc Molecular and magnetic resonance imaging of human embryonic stem cell-derived neural stem cell grafts in ischemic rat brain
    Marcel M Daadi
    Department of Neurosurgery, Stanford Stroke Center, Stanford University School of Medicine, California 94305 5487, USA
    Mol Ther 17:1282-91. 2009
    ..Our data suggest that the combination of BLI and MRI modalities provides reliable real-time monitoring of cell fate...
  20. pmc Transcriptome alteration in the diabetic heart by rosiglitazone: implications for cardiovascular mortality
    Kitchener D Wilson
    Department of Radiology, Stanford University School of Medicine, Stanford, California, United States of America
    PLoS ONE 3:e2609. 2008
    ..To investigate the effects of rosiglitazone on the diabetic heart, we performed cardiac transcriptional profiling and imaging studies of a murine model of type 2 diabetes, the C57BL/KLS-lepr(db)/lepr(db) (db/db) mouse...
  21. pmc Quantum dot imaging for embryonic stem cells
    Shuan Lin
    Molecular Imaging Program at Stanford MIPS and Bio X Program, Department of Radiology, Stanford University, Stanford, CA 94305, USA
    BMC Biotechnol 7:67. 2007
    ..In this report, we aimed to evaluate in vivo multiplex imaging of mouse embryonic stem (ES) cells labeled with Qtracker delivered quantum dots (QDs)...
  22. pmc Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease
    Zongjin Li
    Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Circulation 116:I46-54. 2007
    ....