Yigang Li



  1. Chen J, Cao J, Fang L, Liu B, Zhou Q, Sun Y, et al. Berberine derivatives reduce atherosclerotic plaque size and vulnerability in apoE(-/-) mice. J Transl Med. 2014;12:326 pubmed publisher
    ..These results have demonstrated that BBR derivatives, dhBBR and Di-MeBBR, are superior to BBR in inhibiting inflammation and reducing plaque size and vulnerability. ..
  2. Hou J, Li W, Guo K, Chen X, Chen Y, Li C, et al. Antiarrhythmic effects and potential mechanism of WenXin KeLi in cardiac Purkinje cells. Heart Rhythm. 2016;13:973-82 pubmed publisher
    ..Moreover, WXKL exerted significantly less use-dependent block of I(NaP) than that of flecainide, indicating its lower proarrhythmic effect. WXKL exhibits antiarrhythmic properties in cardiac PCs via selective inhibition of I(NaL). ..
  3. Wang Q, Hu X, Li S, Wang X, Wang J, Zhang R, et al. Association of the angiotensinogen M235T polymorphism with recurrence after catheter ablation of acquired atrial fibrillation. J Renin Angiotensin Aldosterone Syst. 2015;16:888-97 pubmed publisher
    ..These strategies may differ and should be individualized according to patients' genotype. Future studies are warranted to validate the potential effect of AGT M235T on AF recurrence post CA. ..
  4. Yang L, Zhang P, Chen X, Li C, Sun J, Hou J, et al. Semaphorin 3a transfection into the left stellate ganglion reduces susceptibility to ventricular arrhythmias after myocardial infarction in rats. Europace. 2016;18:1886-1896 pubmed publisher
    ..Semaphorin 3a overexpression in the LSG ameliorates the inducibility of ventricular arrhythmias after MI, mainly through attenuation of neural remodelling within the cardiac-neuraxis. ..
  5. Li C, Zhou Q, Yang L, Chen Y, Hou J, Guo K, et al. Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway. Basic Res Cardiol. 2016;111:19 pubmed publisher
    ..Future studies are warranted to test the feasibility of overexpressing Dusp14 as a therapeutic strategy to attenuate cardiac hypertrophy and failure. ..
  6. Yu Y, Ye L, Li Y, Burkin D, DUAN D. Heart-specific overexpression of the human short CLC-3 chloride channel isoform limits myocardial ischemia-induced ERP and QT prolongation. Int J Cardiol. 2016;214:218-24 pubmed publisher
    ..CLC-3 up-regulation may serve as an important adaptive mechanism against myocardial ischemia. ..
  7. Wang Y, Chen G, Li X, Zhou X, Li Y. Prolonged P-wave duration is associated with atrial fibrillation recurrence after radiofrequency catheter ablation: A systematic review and meta-analysis. Int J Cardiol. 2017;227:355-359 pubmed publisher
    ..SROC analysis suggested an acceptable predictive efficiency of PWD for AFR (AUC=0.66). The risk of AFR after RFCA is strongly related to a prolonged PWD. PWD is one potential low-cost and feasible predictor of AFR after RFCA. ..
  8. Li W, Yu Y, Hou J, Zhou Z, Guo K, Zhang P, et al. Larger rate dependence of late sodium current in cardiac Purkinje cells: A potential link to arrhythmogenesis. Heart Rhythm. 2017;14:422-431 pubmed publisher
  9. Chen Y, Wang Q, Li C, Hou J, Chen X, Zhou Q, et al. Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function. J Mol Cell Cardiol. 2017;105:1-11 pubmed publisher

More Information


  1. Fei Y, Li W, Hou J, Guo K, Chen X, Chen Y, et al. Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling. Int J Mol Sci. 2017;18: pubmed publisher
    ..H?O? induced afterdepolarizations via the activation of PKC and the enhancement of ICa,L and INa,L. These results provide evidence of a link between oxidative stress, PKC activation and afterdepolarizations. ..
  2. Wang Q, Yu Y, Zhang P, Chen Y, Li C, Chen J, et al. The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation. Basic Res Cardiol. 2017;112:47 pubmed publisher