Yangqiu Li

Summary

Publications

  1. pmc The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies
    Li Shi
    Institute of Hematology, Jinan University, Guangzhou 510632, China
    J Hematol Oncol 6:74. 2013
  2. pmc Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation
    Qi Shen
    Institute of Hematology, Jinan University, Guangzhou 510632, China
    J Hematol Oncol 6:64. 2013
  3. pmc Changes in the MALT1-A20-NF-κB expression pattern may be related to T cell dysfunction in AML
    Li Shi
    Institute of Hematology, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 13:37. 2013
  4. pmc The differential expression pattern of the BMI-1, SALL4 and ABCA3 genes in myeloid leukemia
    Qi Shen
    Institute of Hematology, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 12:42. 2012
  5. pmc New insights into antigen specific immunotherapy for chronic myeloid leukemia
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 12:52. 2012
  6. pmc The role of A20 in the pathogenesis of lymphocytic malignancy
    Fan Zhang
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Cancer Cell Int 12:44. 2012
  7. pmc The role of BCL11B in hematological malignancy
    Xin Huang
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Exp Hematol Oncol 1:22. 2012
  8. pmc Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemia
    Chunlan Lin
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, People s Republic of China
    Cancer Cell Int 12:13. 2012
  9. pmc Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    J Transl Med 8:47. 2010
  10. doi request reprint Change in expression pattern of TCR-CD3 complex in patients with multiple myeloma
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 16:143-50. 2011

Collaborators

Detail Information

Publications60

  1. pmc The role of PD-1 and PD-L1 in T-cell immune suppression in patients with hematological malignancies
    Li Shi
    Institute of Hematology, Jinan University, Guangzhou 510632, China
    J Hematol Oncol 6:74. 2013
    ..The role of PD-1 and PD-L1 in T-cell immune suppression and the potential for immunotherapy via blocking PD-1 and PD-L1 in hematological malignancies are also reviewed. ..
  2. pmc Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation
    Qi Shen
    Institute of Hematology, Jinan University, Guangzhou 510632, China
    J Hematol Oncol 6:64. 2013
    ..Down-regulating PPP2R5C gene expression might be considered as a new therapeutic target strategy for CML, particularly for imatinib-resistant CML. ..
  3. pmc Changes in the MALT1-A20-NF-κB expression pattern may be related to T cell dysfunction in AML
    Li Shi
    Institute of Hematology, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 13:37. 2013
    ....
  4. pmc The differential expression pattern of the BMI-1, SALL4 and ABCA3 genes in myeloid leukemia
    Qi Shen
    Institute of Hematology, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 12:42. 2012
    ..abstract:..
  5. pmc New insights into antigen specific immunotherapy for chronic myeloid leukemia
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 12:52. 2012
    ....
  6. pmc The role of A20 in the pathogenesis of lymphocytic malignancy
    Fan Zhang
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Cancer Cell Int 12:44. 2012
    ..The identification of A20 mutations and deletions in lymphocytic malignancy and the predictive significance of these aberrations are also reviewed...
  7. pmc The role of BCL11B in hematological malignancy
    Xin Huang
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Exp Hematol Oncol 1:22. 2012
    ..This review summarizes current data and knowledge concerning the alteration of BCL11B in hematological malignancies and its role as a potential target for therapies directed against T cell malignancies...
  8. pmc Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemia
    Chunlan Lin
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, People s Republic of China
    Cancer Cell Int 12:13. 2012
    ..abstract:..
  9. pmc Decreased level of recent thymic emigrants in CD4+ and CD8+T cells from CML patients
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    J Transl Med 8:47. 2010
    ..Based on our previous finding, to further characterize the immune status, T cell proliferative history was analyzed in CD4+ and CD8+ T cells from chronic myeloid leukemia (CML) patients...
  10. doi request reprint Change in expression pattern of TCR-CD3 complex in patients with multiple myeloma
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 16:143-50. 2011
    ..This study contributes to a better understanding of the cellular immune features in MM patients...
  11. pmc Gene expression profiles in BCL11B-siRNA treated malignant T cells
    Xin Huang
    Institute of Hematology, Medical College, Jinan University, Guangzhou, PR China
    J Hematol Oncol 4:23. 2011
    ..The expression profiles of several genes were further validated in the BCL11B-siRNA -treated Molt-4 cells and primary T-ALL cells...
  12. doi request reprint Reduced levels of recent thymic emigrants in acute myeloid leukemia patients
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, 510632 Guangzhou, China
    Cancer Immunol Immunother 58:1047-55. 2009
    ..In the present study, in order to further characterize the T cell immunity in acute myeloid leukemia (AML) patients, the level of recent thymic emigrants (RTE) was analyzed...
  13. ncbi request reprint [The feature of TCR V alpha40 with Jdelta1, Ddelta3 or psiJalpha gene rearrrangements in T cells]
    Yang qiu Li
    Institute of Hematology, Medical College of Jinan University, Guangzhou 510632, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:52-5. 2002
    ..It is concluded that the TCR V alpha40-psi Jalpha was the most frequent rearrangement in mature and immature T cells, whereas TCR Valpha40-Ddelta3 was more frequently rearranged in immature T cells..
  14. doi request reprint Alterations in the expression pattern of TCR zeta chain in T cells from patients with hematological diseases
    Yangqiu Li
    Institute of Hematology, Medical College and Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou 510632, China
    Hematology 13:267-75. 2008
    ....
  15. ncbi request reprint TRAV and TRBV repertoire, clonality and the proliferative history of umbilical cord blood T-cells
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    Transpl Immunol 18:151-8. 2007
    ..The incomplete repertoire and naivety of CB T-cells might be the reason that CB hematopoietic stem cells transplant recipients are less likely to develop graft vs host disease...
  16. ncbi request reprint The TCR Vbeta repertoire usage of T-cells from cord blood induced by chronic myelogenous leukemia associated antigen
    Yangqiu Li
    Institute of Hematology, Medical College of Jinan University, Guangzhou, China
    Hematology 10:387-92. 2005
    ....
  17. ncbi request reprint Recent thymic output function in patients with hematological malignancy
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Hematology 10:297-305. 2005
    ....
  18. doi request reprint TRGV and TRDV repertoire distribution and clonality of T cells from umbilical cord blood
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Transpl Immunol 20:155-62. 2009
    ..However, this study will definitively contribute to understand the cellular immune features better and to exploit more efficiently the therapeutic potentials of CB...
  19. doi request reprint BCL11B suppression does not influence CD34(+) cell differentiation and proliferation
    Qi Shen
    Institute of Hematology, Medical College, Jinan University, Guangzhou, PR China
    Hematology 17:329-33. 2012
    ..In conclusion, the BCL11B-siRNA935 used in this study may be safe, and BCL11B may be considered a new candidate for targeted gene therapy in T-cell malignancies...
  20. doi request reprint The role of BCL11B in regulating the proliferation of human naive T cells
    Si Chen
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, People s Republic of China
    Hum Immunol 73:456-64. 2012
    ..In conclusion, BCL11B is required for T-cell survival; its overexpression could effectively increase the T-cell activation and proliferation abilities and Th-cell differentiation as well...
  21. ncbi request reprint Down regulation of BCL11B expression inhibits proliferation and induces apoptosis in malignant T cells by BCL11B-935-siRNA
    Xin Huang
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 16:236-42. 2011
    ..Suppression of BCL11B by RNA interference could inhibit the proliferation and induce the apoptosis effectively in leukemic T cells, which might be considered as a new target therapeutic strategy in T-cell malignancies...
  22. pmc Alternative expression of TCRζ related genes in patients with chronic myeloid leukemia
    Xianfeng Zha
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, China
    J Hematol Oncol 5:74. 2012
    ..The characteristics of TCRζ 3'-UTR alternative splicing may be a novel immunological marker for the evaluation of the CML immune status...
  23. doi request reprint A change in CD3γ, CD3δ, CD3ϵ, and CD3ζ gene expression in T-lymphocytes from benzene-exposed and benzene-poisoned workers
    Bo Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, PR China
    J Immunotoxicol 9:160-7. 2012
    ..For now, it is hoped that this study may contribute to a better understanding of the disorders in cellular immunity frequently found with benzene-exposed workers...
  24. pmc Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia
    Xin Huang
    Institute of Hematology, Medical College, Jinan University, and Department of Hematology, Guangdong General Hospital, Guangzhou, 510632, PR China
    J Hematol Oncol 3:44. 2010
    ....
  25. ncbi request reprint Gene expression profiling of CD3gamma, delta, epsilon, and zeta chains in CD4(+) and CD8(+) T cells from human umbilical cord blood
    Shaohua Chen
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 15:230-5. 2010
    ..Higher expression of CD3 genes in CD4(+) T cells might relate to the strong ability of activation of TCR-mediated signals, and suggests that this is one of the features responsible for the low allo-reactivity of CB T cells...
  26. doi request reprint Alteration of the gene expression profile of T-cell receptor αβ-modified T-cells with diffuse large B-cell lymphoma specificity
    Xianfeng Zha
    Jinan University, Guangzhou, China
    Hematology 18:138-43. 2013
    ..The changes corresponded to an up-regulation in the differentiation and proliferation of the T-cells. These data may help to explain some of the characteristics of the redirected T-cells...
  27. pmc Expression and distribution of PPP2R5C gene in leukemia
    Haitao Zheng
    Institute of Hematology, Medical College, Jinan University, Guangzhou, People s Republic of China
    J Hematol Oncol 4:21. 2011
    ....
  28. pmc Upregulated TCRζ enhances interleukin-2 production in T-cells from patients with CML
    Xianfeng Zha
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    DNA Cell Biol 31:1628-35. 2012
    ..It is possible that TCRζ chain reconstitution in leukemia-specific, clonally expanded T cells will effectively increase their activation of antileukemia cytotoxicity...
  29. pmc Differential gene expression profiles of PPP2R5C-siRNA-treated malignant T cells
    Yu Chen
    1 Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou, China
    DNA Cell Biol 32:573-81. 2013
    ....
  30. pmc Altered expression of the TCR signaling related genes CD3 and FcεRIγ in patients with aplastic anemia
    Bo Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    J Hematol Oncol 5:6. 2012
    ..However, primary and secondary failure after immunosuppressive therapy is frequent. Thus, knowledge of the immune mechanisms leading to AA is crucial to fundamentally understand the disease...
  31. doi request reprint The expression pattern of CD3 chain genes in fetal/maternal interface
    Xiaoye Lu
    Department of Histology and Embryology, Medical College, Jinan University, Guangzhou, China
    Hematology 16:185-9. 2011
    ..In conclusion, the present study characterized the expression pattern of CD3-gamma, -delta, -epsilon and -zeta chain genes from placenta, which contributes to further understanding of the features of T-cell immune status in placenta...
  32. pmc Frequency analysis of TRBV subfamily sjTRECs to characterize T-cell reconstitution in acute leukemia patients after allogeneic hematopoietic stem cell transplantation
    Xiuli Wu
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, PR China
    J Hematol Oncol 4:19. 2011
    ..To assess the proliferative history in different T-cell receptor beta variable region (TRBV) subfamilies of T cells after HSCT, expansion of TRBV subfamily-naive T cells was determined by analysis of a series of TRBV-BD1 sjTRECs...
  33. ncbi request reprint The feature of TRGV and TRDV repertoire distribution and clonality in patients with immune thrombocytopenic purpura
    Xueli Zhang
    Department of Hematology, First Affiliated Hospital, Jinan University, Guangzhou 510632, China
    Hematology 14:237-44. 2009
    ..In conclusion, the alteration of peripheral TRGV and TRDV repertoire pattern might play a role in the pathogenesis of immune-mediated platelet destruction in some cases with ITP...
  34. doi request reprint Characterization of the CDR3 structure of the Vβ21 T cell clone in patients with P210(BCR-ABL)-positive chronic myeloid leukemia and B-cell acute lymphoblastic leukemia
    Xianfeng Zha
    Institute of Hematology, Medical College, Jihan University, Guangzhou, China
    Hum Immunol 72:798-804. 2011
    ..The characterization of the CDR3 structure was complex. Regrettably, at this time it was not possible to confirm that the Vβ21 T cell clones were derived from the stimulation of p210(BCR-ABL) protein...
  35. pmc Evolution of T-cell clonality in a patient with Ph-negative acute lymphocytic leukemia occurring after interferon and imatinib therapy for Ph-positive chronic myeloid leukemia
    Liang Wang
    Department of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, 510632, PR China
    J Hematol Oncol 3:14. 2010
    ..The features of restrictive usage and absence of partial T cell clones have been found in patients with CML. However, the T-cell clonal evolution of Ph-negative malignancies during treatment for CML is still unknown...
  36. doi request reprint The T-cell receptor Vbeta gene repertoire and clonal expansion from peripheral blood T cells in benzene-exposed workers in China
    Bo Li
    Institute of Hematology, Medical College, Jinan University, China
    Hematology 14:106-10. 2009
    ..05). The most frequently used Vbeta genes were Vbeta3, Vbeta21, Vbeta6, and Vbeta16. We observed a skewed distribution and clonal expansion of TCR Vbeta subfamilies in benzene-exposed workers...
  37. doi request reprint Restricted TRBV repertoire in CD4+ and CD8+ T-cell subsets from CML patients
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 16:43-9. 2011
    ..In conclusion, the restricted expression of TRBV subfamilies indicates the T-cell immunodeficiency in CML patients; however, clonally expanded T cells suggest a specific immune response to leukemia associated antigens...
  38. doi request reprint Characterization of conserved CDR3 sequence of TCR alpha- and beta-chain genes in peripheral blood T-cells from patients with diffuse large B-cell lymphoma
    Qingsong Yin
    Institute of Hematology, Jinan University, Guangzhou, China
    Hematology 15:48-57. 2010
    ..These findings revealed the mono/oligoclonally expanded T cells were derived from the stimulation of some antigens in the PB of patients with DLBCL, and may be recognizing an identical antigenic epitope...
  39. ncbi request reprint Clonal expanded TCR Vbeta T cells in patients with APL
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Hematology 10:135-9. 2005
    ..The clonal expansion of T-cells were considered to be a specific anti-leukemic immune response by host T-cells activated by the leukemia-associated-antigen...
  40. doi request reprint Enhancement of specific cellular immune response induced by DNA vaccines encoding PML-RARalpha and hIL-2 genes
    Dongzhi Cen
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 15:88-95. 2010
    ..Our results indicate that a DNA vaccine with PML fusion gene segment and hIL-2 together might elicit increased cellular immune responses in mice...
  41. doi request reprint TCR zeta chain expression in T cells from patients with CML
    Si Chen
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 14:95-100. 2009
    ..Taken together, these results indicate that TCR zeta chain expression was decreased in PBMCs and CD4+ T cells from patients with CML and this could be up-regulated partially by using stimulators...
  42. pmc The feature of distribution and clonality of TCR γ/δ subfamilies T cells in patients with B-cell non-Hodgkin lymphoma
    Liang Wang
    Department of Oncology, First Affiliated Hospital, Jinan University, Guangzhou 510632, China
    J Immunol Res 2014:241246. 2014
    ....
  43. pmc Alternative expression pattern of MALT1-A20-NF-κB in patients with rheumatoid arthritis
    Xu Wang
    Institute of Hematology, Jinan University, Guangzhou 510632, China Key Laboratory for Regenerative Medicine of Ministry of Education, Jinan University, Guangzhou 510632, China
    J Immunol Res 2014:492872. 2014
    ..In conclusion, we first characterized the alternative expression pattern of MALT1, A20, and NF-κB in RA, which may be related to abnormal T cell activation. ..
  44. pmc Distribution and clonality of the vα and vβ T-cell receptor repertoire of regulatory T cells in leukemia patients with and without graft versus host disease
    Zhenyi Jin
    1 Institute of Hematology, Jinan University, Guangzhou, China
    DNA Cell Biol 33:182-8. 2014
    ..Restricted utilization of the Vα and Vβ subfamilies and the absence of some important TCR rearrangements in Treg cells may be related to GVHD due to a lower regulating function of Treg subfamilies. ..
  45. pmc The TCR γδ repertoire and relative gene expression characteristics of T-ALL cases with biclonal malignant Vδ1 and Vδ2 T cells
    Haitao Zheng
    1 Institute of Hematology, Jinan University, Guangzhou, People s Republic of China
    DNA Cell Biol 33:49-56. 2014
    ..Thus, our findings may improve the understanding of biclonal T-ALL. ..
  46. ncbi request reprint [Expression down-regulation of c-Cbl and Cbl-b genes in peripheral blood mononuclear cells from multiple myeloma patients]
    Su Fang
    Institute of Hematology, Jinan University, Guangzhou, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29:842-5. 2013
    ..To investigate c-Cbl and Cbl-b gene expressions in peripheral blood mononuclear cells (PBMCs) from multiple myeloma (MM) patients...
  47. pmc Generation of diffuse large B cell lymphoma-associated antigen-specific Vα6/Vβ13+T cells by TCR gene transfer
    Qingsong Yin
    Institute of Hematology, Medical College, Jinan University, Guangzhou, 510632, PR China
    J Hematol Oncol 4:2. 2011
    ..The transfer of T cell receptor (TCR) genes endows T cells with new antigen specificity. Therefore, the aim of this study is to generate diffuse large B cell lymphoma (DLBCL)-specific T cells by T cell receptor (TCR) gene transfer...
  48. ncbi request reprint Clonal expansion T cells identified in acute monoblastic leukemia by CDR3 size analysis of TCR V beta repertoire using RT-PCR and genescan
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Chin Med J (Engl) 115:69-71. 2002
    ..To investigate the distribution and clonality of T cell receptor (TCR) V beta repertoire in patients with acute monoblastic leukemia (AML-M5)...
  49. pmc A BCR/ABL-hIL-2 DNA vaccine enhances the immune responses in BALB/c mice
    Yanan Qin
    Department of Microbiology and Immunology, Medical College, Jinan University, Guangzhou 510632, China
    Biomed Res Int 2013:136492. 2013
    ..These results indicate that a DNA vaccine containing BCR/ABL and hIL-2 together may elicit increased in vivo humoral and cellular immune responses in BALB/c mice. ..
  50. ncbi request reprint GATA-1, -2 and -3 genes expression in bone marrow microenviroment with chronic aplastic anemia
    Xiuli Wu
    Medical College, Institute of Hematology, Jinan University, Guangzhou, PR China
    Hematology 12:331-5. 2007
    ..The change of expression levels of GATA genes may influence the hematopoiesis in BM microenvironment and relate to the pathogenesis and development of aplastic anemia...
  51. ncbi request reprint Evaluation of TCR Vbeta subfamily T cell expansion in NOD/SCID mice transplanted with human cord blood hematopoietic stem cells
    Chen Lin
    Department of Microbiology and Immunology, Medical College of Jinan University, Guangzhou, PR China
    Hematology 12:325-30. 2007
    ..The restricted expression and clonal expansion of some CB T cell clones may be induced by tissue-antigens of NOD/SCID mice...
  52. doi request reprint Deficiency of CD3gamma, delta, epsilon, and zeta expression in T cells from AML patients
    Shaohua Chen
    Institute of Hematology, Medical College, Jinan University, Guangzhou, China
    Hematology 16:31-6. 2011
    ..Deficiency of all four CD3 gene expression levels might represent the feature related to T-cell immunodeficiency...
  53. ncbi request reprint [Expression of reconstructed BCR-ABL-pIRES-SEA plasmids in the skeletal muscles of BALB/c mice]
    Yongpeng Gao
    Department of Microbiology and Immunology, Medical College, Jinan University, Guangzhou 510632, China
    Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 29:519-23. 2012
    ..The reconstructed BCR-ABL-pIRES-SEA plasmids can effectively express gene production in the skeletal muscles of mice and have the common features of DNA vaccine...
  54. ncbi request reprint Leukemia associated clonal expansion of TCR Vbeta subfamily T cells
    Yangqiu Li
    Institute of Hematology, Medical College, Jinan University, Guangzhou 510632, China
    Hematology 8:375-84. 2003
    ..Understanding such clonality and restricted usage of TCR Vbeta repertoire of leukemia-associated expanded T cells may be useful for the design of new immuno-therapeutic strategy for leukemia...
  55. pmc SEA antagonizes the imatinib-meditated inhibitory effects on T cell activation via the TCR signaling pathway
    Guanming Wang
    Department of Microbiology and Immunology, Medical College, Jinan University, Guangzhou 510632, China Quanzhou Medical college, Quanzhou 362000, China
    Biomed Res Int 2014:682010. 2014
    ..It is conceivable that SEA antagonizes the imatinib-mediated inhibition of T cell activation and proliferation through the TCR signaling pathway. ..
  56. pmc Notch1 signaling is involved in regulating Foxp3 expression in T-ALL
    Xiaodan Luo
    Department of Oncology and Hematology, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, 510230, China
    Cancer Cell Int 13:34. 2013
    ..We studied Foxp3 and Notch1 expression in vivo and in vitro, and analyzed the biological characteristics of T-ALL cell line systematically after Notch inhibition and explored the crosstalk between Notch signaling and Foxp3 expression...
  57. doi request reprint Foxp3 gene expression in oral lichen planus: a clinicopathological study
    Lei Lei
    Department of Stomatology, Medical College of Jinan University, Guangzhou, Guangdong 510632, P R China
    Mol Med Rep 9:928-34. 2014
    ..05). This study indicated that Foxp3 expression in patients with OLP is associated with the severity and duration of the disorder, suggesting altered immune suppression in the development, clinical course and responsiveness to treatment...
  58. pmc The role of peptide and DNA vaccines in myeloid leukemia immunotherapy
    Chen Lin
    Department of Microbiology and Immunology, Medical College, Jinan University, Guangzhou, 510632, China
    Cancer Cell Int 13:13. 2013
    ..This review will focus on peptides and DNA vaccines in the context of myeloid leukemias, and optimal strategies for enhancing the efficacy of vaccines based on myeloid leukemia immunization are also summarized...
  59. ncbi request reprint KDR and Sema3 genes expression in bone marrow stromal cells and hematopoietic cells from leukemia patients and normal individuals
    Zhen Wang
    Guangdong Provincial Lung Cancer Research Institute, Cancer Center, Guangdong Provincial People s Hospital, Guangzhou 510800, P R China
    Hematology 10:307-12. 2005
    ..Sema3 could also sustain the survival of hematopoietic cells with its high expression, while Sema3 gene expression may be inhibited in AML and CML...