Hui Li

Summary

Publications

  1. pmc Human migration through bottlenecks from Southeast Asia into East Asia during Last Glacial Maximum revealed by Y chromosomes
    Xiaoyun Cai
    Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    PLoS ONE 6:e24282. 2011
  2. pmc Paternal genetic structure of Hainan aborigines isolated at the entrance to East Asia
    Dongna Li
    Department of Biology, Hainan Medical College, Haikou, Hainan, China
    PLoS ONE 3:e2168. 2008
  3. pmc Inferring human history in East Asia from Y chromosomes
    Chuan Chao Wang
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, 220 Handan Road, Shanghai, China
    Investig Genet 4:11. 2013
  4. pmc High diversity and no significant selection signal of human ADH1B gene in Tibet
    Yan Lu
    State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
    Investig Genet 3:23. 2012
  5. pmc Paternal genetic affinity between Western Austronesians and Daic populations
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes for Biomedical Sciences, Fudan University, Shanghai 200433, China
    BMC Evol Biol 8:146. 2008
  6. ncbi request reprint Genetic origin of Kadai-speaking Gelong people on Hainan island viewed from Y chromosomes
    Dongna Li
    Department of Biology, Hainan Medical College, Haikou, Hainan, China
    J Hum Genet 55:462-8. 2010
  7. ncbi request reprint Mitochondrial DNA diversity and population differentiation in southern East Asia
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Am J Phys Anthropol 134:481-8. 2007
  8. ncbi request reprint Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai, China
    Mol Biol Evol 22:725-34. 2005
  9. pmc Down-regulation of SIX3 is associated with clinical outcome in lung adenocarcinoma
    Min Li Mo
    School of Life Sciences, Tsinghua University, Beijing, China
    PLoS ONE 8:e71816. 2013
  10. doi request reprint Y-chromosome O3 haplogroup diversity in Sino-Tibetan populations reveals two migration routes into the eastern Himalayas
    Longli Kang
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Ann Hum Genet 76:92-9. 2012

Collaborators

Detail Information

Publications64

  1. pmc Human migration through bottlenecks from Southeast Asia into East Asia during Last Glacial Maximum revealed by Y chromosomes
    Xiaoyun Cai
    Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    PLoS ONE 6:e24282. 2011
    ..The ages of O3a3b-M7 and O3a3c1-M117 were estimated to be approximately 19 thousand years, followed by the emergence of the ancestors of HM lineages out of MK and the unidirectional northward migrations into East Asia...
  2. pmc Paternal genetic structure of Hainan aborigines isolated at the entrance to East Asia
    Dongna Li
    Department of Biology, Hainan Medical College, Haikou, Hainan, China
    PLoS ONE 3:e2168. 2008
    ..At the southern entrance to East Asia, early population migration has affected most of the Y-chromosome variations of East Asians...
  3. pmc Inferring human history in East Asia from Y chromosomes
    Chuan Chao Wang
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, 220 Handan Road, Shanghai, China
    Investig Genet 4:11. 2013
    ..Furthermore, application of Y chromosome analyses in the family genealogy studies offers successful showcases of the utility of genetics in studying the ancient history. ..
  4. pmc High diversity and no significant selection signal of human ADH1B gene in Tibet
    Yan Lu
    State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
    Investig Genet 3:23. 2012
    ..abstract:..
  5. pmc Paternal genetic affinity between Western Austronesians and Daic populations
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes for Biomedical Sciences, Fudan University, Shanghai 200433, China
    BMC Evol Biol 8:146. 2008
    ....
  6. ncbi request reprint Genetic origin of Kadai-speaking Gelong people on Hainan island viewed from Y chromosomes
    Dongna Li
    Department of Biology, Hainan Medical College, Haikou, Hainan, China
    J Hum Genet 55:462-8. 2010
    ..However, this identification is invalid until it is accepted by the Gelong people themselves and the Hainan government...
  7. ncbi request reprint Mitochondrial DNA diversity and population differentiation in southern East Asia
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology and Center for Evolutionary Biology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Am J Phys Anthropol 134:481-8. 2007
    ..MtDNA data of Daic, Austro-Asiatic and other populations in South China has therefore proven pivotal for studying the human history of East Asia...
  8. ncbi request reprint Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai, China
    Mol Biol Evol 22:725-34. 2005
    ..Moreover, our data defined some new (sub-)haplogroups (A6, B4e, B4f, C5, F1a1, F1a1a, and R9c), which will direct further efforts to improve the phylogeny of East Asian mtDNAs...
  9. pmc Down-regulation of SIX3 is associated with clinical outcome in lung adenocarcinoma
    Min Li Mo
    School of Life Sciences, Tsinghua University, Beijing, China
    PLoS ONE 8:e71816. 2013
    ..Little is known about the role of SIX3 in human tumorigenesis. This study is to assess the expression/function of SIX3 and the significance of SIX3 as a prognostic biomarker in lung adenocarcinoma...
  10. doi request reprint Y-chromosome O3 haplogroup diversity in Sino-Tibetan populations reveals two migration routes into the eastern Himalayas
    Longli Kang
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Ann Hum Genet 76:92-9. 2012
    ..Thus, we have shown that populations with haplogroup O3 moved into the eastern Himalayas through at least two routes...
  11. pmc Combined EGFR and VEGFR versus single EGFR signaling pathways inhibition therapy for NSCLC: a systematic review and meta-analysis
    Xinji Zhang
    Department of Health Statistics, Second Military Medical University, Shanghai, China
    PLoS ONE 7:e40178. 2012
    ..Hence, a meta-analysis comparing therapy inhibiting both VEGFR and EGFR signaling pathways with that inhibiting EGFR signaling pathway alone was performed...
  12. ncbi request reprint Genetic evidence supports demic diffusion of Han culture
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, School of Life Sciences and Morgan Tan International Center for Life Sciences, Fudan University, Shanghai 200433, China
    Nature 431:302-5. 2004
    ..16 billion (2000 census), and are by far the largest ethnic group in the world. The expansion process of Han culture is thus of great interest to researchers in many fields...
  13. doi request reprint Mitochondrial origin of the matrilocal Mosuo people in China
    Yan Lu
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, People s Republic of China
    Mitochondrial DNA 23:13-9. 2012
    ..Therefore, we concluded that the Mosuo people have the closest genetic relationship with the Pumi, and that they started to practice matrilocality several thousand years ago...
  14. doi request reprint A mitochondrial revelation of early human migrations to the Tibetan Plateau before and after the last glacial maximum
    Zhendong Qin
    State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, China
    Am J Phys Anthropol 143:555-69. 2010
    ....
  15. doi request reprint 3,5-Diiodo-l-thyronine ameliorates diabetic nephropathy in streptozotocin-induced diabetic rats
    Guoguo Shang
    Department of Pathology, Fudan University, Shanghai, People s Republic of China
    Biochim Biophys Acta 1832:674-84. 2013
    ..Collectively, these results suggested that T2 was a protective agent against renal damage in diabetic nephropathy, whose action involved regulation of SIRT1...
  16. ncbi request reprint Y chromosomes of prehistoric people along the Yangtze River
    Hui Li
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai 200433, China
    Hum Genet 122:383-8. 2007
    ..Noticeable genetic segregation was observed among the prehistoric cultures, demonstrating the genetic foundation of the multiple origins of the Chinese Civilization...
  17. ncbi request reprint [Genetic structure of Tujia as revealed by Y chromosomes]
    Xuan Hua Xie
    Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai 200433, China
    Yi Chuan Xue Bao 31:1023-9. 2004
    ....
  18. pmc Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer
    Lili Ji
    Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, China
    PLoS ONE 8:e63404. 2013
    ..Taken together, theses data suggested that Nrf2-ARE pathway is required for the regulatory expression of Mrp1 and implicated Nrf2 as a new therapeutic target for MDR...
  19. ncbi request reprint Aldose reductase regulates TGF-beta1-induced production of fibronectin and type IV collagen in cultured rat mesangial cells
    Tao Jiang
    Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, China
    Nephrology (Carlton) 11:105-12. 2006
    ..To study the effects of aldose reductase (AR) on production of fibronectin and type IV collagen in rat mesangial cells (MsC)...
  20. doi request reprint Pemetrexed plus platinum or gemcitabine plus platinum for advanced non-small cell lung cancer: final survival analysis from a multicentre randomized phase II trial in the East Asia region and a meta-analysis
    Xinji Zhang
    Department of Health Statistics, Eastern Hepatobiliary Surgery Hospital, Shanghai, China
    Respirology 18:131-9. 2013
    ..An additional meta-analysis was performed to systematically evaluate pemetrexed/platinum as first-line treatment for advanced NSCLC...
  21. pmc Major population expansion of East Asians began before neolithic time: evidence of mtDNA genomes
    Hong Xiang Zheng
    State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    PLoS ONE 6:e25835. 2011
    ..The results suggest that the population growth in East Asia constituted a need for the introduction of agriculture and might be one of the driving forces that led to the further development of agriculture...
  22. doi request reprint Positive selection on mitochondrial M7 lineages among the Gelong people in Hainan
    Kun Yang
    School of Agronomy, Hainan University, Haikou, Hainan, China
    J Hum Genet 56:253-6. 2011
    ..In the future, whole mitochondrial genome sequencing might reveal the functional advantage of the M7 lineages...
  23. doi request reprint Gut CaVP is an innate immune protein against bacterial challenge in amphioxus Branchiostoma belcheri
    Zhen Hong Zhuang
    Center for Proteomics, Department of Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People s Republic of China
    Fish Shellfish Immunol 31:217-23. 2011
    ..parahaemolyticus and challenge by Gram-positive Staphylococcus aureus. These findings indicate the importance of gut CaVP in response to bacterial challenge...
  24. ncbi request reprint Overactivated neddylation pathway as a therapeutic target in lung cancer
    Lihui Li
    Affiliations of authors Cancer Institute, Fudan University Shanghai Cancer Center LL, Gy, PC, DW, CL, WY, YW, LJ, Department of Oncology, Shanghai Medical College LL, Gy, PC, DW, CL, WY, YW, LJ, Department of Immunology, School of Basic Medical Sciences LL, Gy, CL, YW, YC, LJ, Clinical Statistics Center, Department of Radiation Oncology, Fudan University Shanghai Cancer Center JZ, LX, HJ, and Liver Cancer Institute, Zhongshan Hospital JS, QG, Fudan University, Shanghai, Detroit
    J Natl Cancer Inst 106:dju083. 2014
    ..A number of oncoproteins and tumor suppressors are known to be neddylated, but whether the neddylation pathway is entirely activated in human cancer remains unexplored...
  25. ncbi request reprint [Origin of Hakka and Hakkanese: a genetics analysis]
    Hui Li
    Center for Anthropological Studies at Fudan University, Shanghai 200433, China
    Yi Chuan Xue Bao 30:873-80. 2003
    ..Southern Chinese dialects, such as Hakkanese may also be those languages of Southern aborigines at first, and turn to extant appearance under the continuance effect of Northern Chinese...
  26. pmc An updated tree of Y-chromosome Haplogroup O and revised phylogenetic positions of mutations P164 and PK4
    Shi Yan
    State Key Laboratory of Genetic Engineering and Ministry of Education, Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai, China
    Eur J Hum Genet 19:1013-5. 2011
    ..The marker PK4 is also relocated from downstream of M88 to upstream of M95, separating the former O2(*) into two parts. This revision evidently improved the resolving power of Y-chromosome phylogeny in East Asia...
  27. doi request reprint Present Y chromosomes reveal the ancestry of Emperor CAO Cao of 1800 years ago
    Chuanchao Wang
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Department of History, Fudan University, Shanghai, China
    J Hum Genet 57:216-8. 2012
    ..Therefore, Emperor CAO Cao's claim was not supported by genetic evidence. This study offers a successful showcase of the utility of genetics in studying the ancient history...
  28. doi request reprint Dermatoglyphic changes during the population admixture between Kam and Han Chinese
    Xu Cheng
    MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, 220 Handan Road, Shanghai 200433, China
    Homo 60:143-57. 2009
    ..These dermatoglyphic changes may result from increased heterozygosity in the admixed population. The genetic modes of these changes may be relatively simple and will be useful for future dermatoglyph genetic studies...
  29. ncbi request reprint Construction of novel bifunctional chimeric proteins possessing antitumor and thrombolytic activities
    Jing Hui
    Laboratory of Biomaterials and Biopharmaceuticals, School of Life Sciences, Liaoning University, Shenyang, 110036, China
    J Microbiol Biotechnol 22:894-901. 2012
    ..Neither the SEC2 or Sak component of each chimeric protein affected the activity of the other component. The results presented in this study provide a possible strategy to prevent and cure tumor thrombus...
  30. doi request reprint 2,4-Dichlorophenol induces global DNA hypermethylation through the increase of S-adenosylmethionine and the upregulation of DNMTs mRNA in the liver of goldfish Carassius auratus
    Xiaoning Zhang
    School of Life Sciences, Lanzhou University, Lanzhou 730000, China
    Comp Biochem Physiol C Toxicol Pharmacol 160:54-9. 2014
    ..Our report is the first one to show that short-term 2,4-DCP exposure caused the global DNA hypermethylation via altered SAM level and DNMTs expression in fish. ..
  31. doi request reprint DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection
    Zhiquan Wang
    Laboratory of Neurodegenerative Diseases, Institute of Health Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Science and Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Ann Neurol 70:591-9. 2011
    ..However, the mechanisms underlying dopaminergic neuron loss related to DJ-1 mutation remain undefined. Therefore, it is important to find the new mechanisms underlying the antioxidative functions of DJ-1...
  32. doi request reprint Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways
    Chenghai Li
    Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
    J Bone Miner Res 26:644-56. 2011
    ..Together our data demonstrate that MA suppresses RANKL-induced osteoclastogenesis through NF-κB and MAPK/AP-1 signaling pathways and that MA is a promising agent in the treatment of osteoclast-related diseases such as osteoporosis...
  33. pmc Detection of E2A-PBX1 fusion transcripts in human non-small-cell lung cancer
    Min Li Mo
    School of Life Sciences, Tsinghua University, Beijing 10084, China
    J Exp Clin Cancer Res 32:29. 2013
    ..E2A-PBX1 fusion gene caused by t(1;19)(q23;p13), has been well characterized in acute lymphoid leukemia (ALL). There is no report on E2A-PBX1 fusion transcripts in non-small-cell lung cancer (NSCLC)...
  34. pmc Adverse drug reactions of spontaneous reports in shanghai pediatric population
    Hui Li
    Department of Health Statistics, Second Military Medical University, Shanghai, China
    PLoS ONE 9:e89829. 2014
    ..Knowledge of drug safety in the pediatric population of China is limited. This study was designed to evaluate ADRs in children reported to the spontaneous reporting system (SRS) of Shanghai in 2009...
  35. pmc Adoptive immunotherapy in postoperative hepatocellular carcinoma: a systemic review
    Feng Xie
    Department of Health Statistics, The Second Military Medical University, Shanghai, China
    PLoS ONE 7:e42879. 2012
    ..To address this issue, we did a systemic review of the literatures and analyzed the data with emphasis on the recurrence and survival...
  36. doi request reprint Identification of plasma-responsive outer membrane proteins and their vaccine potential in Edwardsiella tarda using proteomic approach
    Chao Wang
    Center for Proteomics, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou 510275, China
    J Proteomics 75:1263-75. 2012
    ....
  37. ncbi request reprint EGCG inhibits Cd(2+)-induced apoptosis through scavenging ROS rather than chelating Cd(2+) in HL-7702 cells
    Zhen An
    School of Life Sciences, Lanzhou University, Lanzhou, Gansu, China
    Toxicol Mech Methods 24:259-67. 2014
    ..Therefore, a clear conclusion from this work can be made that EGCG could inhibit Cd(2+)-induced apoptosis by acting as a ROS scavenger rather than a metal chelating agent. ..
  38. ncbi request reprint [Genotyping and parental related methylation of SNRPN gene rs220030]
    Hui Li
    Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Fa Yi Xue Za Zhi 29:103-6, 115. 2013
    ..To establish an analytical technique for detecting CpG methylation status by pyrosequencing and to further investigate the feasibility of applying rs220030 to the determination of parental origin allele...
  39. doi request reprint Measurements of normal nasal airway assessed by 3-dimensional computed tomography in Chinese children and adolescents
    Hui Li
    Department of Oral and Maxillofacial Surgery, College of Stomatology, Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China
    Int J Pediatr Otorhinolaryngol 77:180-3. 2013
    ..To establish normative data of nasal airway dimensions in Chinese children and adolescents by age and sex...
  40. pmc Adenoviral delivery of the EMX2 gene suppresses growth in human gastric cancer
    Jie Li
    Protein Science Laboratory of Ministry of Education, School of Life Sciences, Tsinghua University, Beijing, China
    PLoS ONE 7:e45970. 2012
    ..Recent studies suggest possible involvement of EMX2 in human cancers; however, the role of EMX2 in carcinogenesis needs further exploration...
  41. doi request reprint Conditioned medium from alternatively activated macrophages induce mesangial cell apoptosis via the effect of Fas
    Yuan Huang
    Department of Pathology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China
    Exp Cell Res 319:3051-7. 2013
    ..Our findings provide compelling evidence that M2 macrophages control the growth of mesangial cells in renal inflammatory conditions. ..
  42. doi request reprint Cervical carcinoma cells stimulate the angiogenesis through TSLP promoting growth and activation of vascular endothelial cells
    Feng Xie
    Laboratory for Reproductive Immunology, Hospital and Institute of Obstetrics and Gynecology, IBS, Fudan University Shanghai Medical College, Shanghai, China
    Am J Reprod Immunol 70:69-79. 2013
    ..To explore whether cervical carcinomas cells-derived thymic stromal lymphopoietin (TSLP) modulates the biologic behavior of vascular endothelial cells and herein participates in the angiogenesis in the cervical cancer pathogenesis...
  43. pmc SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation
    Chao Huang
    Department of Cell Biology, Key Laboratory of The Education Ministry for Cell Differentiation and Apoptosis, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    EMBO J 28:2748-62. 2009
    ..In vivo nude mouse xenografts overexpressing SENP3 are more angiogenic. Taken together, our results identify SENP3 as a redox sensor that regulates HIF-1 transcriptional activity under oxidative stress through the de-SUMOylation of p300...
  44. doi request reprint Aldose reductase regulates TNF-α-induced inducible nitric oxide synthase expression in human mesangial cells
    Jingjing Zhao
    Department of Pathology, Shanghai Medical School, Fudan University, 138 Yi Xue Yuan Road, Shanghai 200032, China
    Mol Biol Rep 39:1815-22. 2012
    ..Taken together, these data demonstrate the role of AR in regulating iNOS expression induced by TNF-α in cultured HMC, indicating the novel function of AR in glomerulonephritis besides glucose metabolism...
  45. pmc Reprogramming of ovine adult fibroblasts to pluripotency via drug-inducible expression of defined factors
    Lei Bao
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China
    Cell Res 21:600-8. 2011
    ..Moreover, sheep iPS cells may be directly used to generate precise gene-modified sheep...
  46. doi request reprint The intracellular plasmid DNA localization of cationic reducible cholesterol-disulfide lipids
    Ruilong Sheng
    Laboratory of Polymer Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China
    Biomaterials 32:3507-19. 2011
    ..In general, these may pave a new way to utilize cholesterol, amino acids and other functional natural products to prepare efficient gene/drug delivery carriers with simple structure and low cytotoxicity...
  47. ncbi request reprint HGF protects rat mesangial cells from high-glucose-mediated oxidative stress
    Hui Li
    Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, PR China
    Am J Nephrol 26:519-30. 2006
    ..The aim of the present study was to evaluate whether HGF could prevent rat mesangial cells (RMC) from high-glucose-mediated oxidative stress and explore its relevant mechanism...
  48. pmc Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans
    Bo Wen
    State Key Laboratory of Genetic Engineering and Center for Anthropological Studies, Fudan University, Shanghai, China
    Am J Hum Genet 74:856-65. 2004
    ..This is the first genetic evidence revealing sex-biased admixture in STB populations, which has genetic, historical, and anthropological implications...
  49. ncbi request reprint Ly-1 antibody reactive clone is an important nucleolar protein for control of self-renewal and differentiation in embryonic stem cells
    Hui Li
    Shanghai Stem Cell Institute, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Stem Cells 27:1244-54. 2009
    ....
  50. doi request reprint Autografts and xenografts of skin fibroblasts delivering BMP-2 effectively promote orthotopic and ectopic osteogenesis
    Rongying Wang
    Department of Cell Biology, Key Laboratory of The Education Ministry for Cell Differentiation and Apoptosis, The Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Anat Rec (Hoboken) 292:777-86. 2009
    ..The success of bone regeneration in calvaria defects induced by the autologous hBMP-2-modified skin fibroblasts provides evidence that fibroblasts could be effectively used in ex vivo gene therapy for local bone repair...
  51. doi request reprint 2,4-dichlorophenol induces apoptosis in primary hepatocytes of grass carp (Ctenopharyngodon idella) through mitochondrial pathway
    Hui Li
    School of Life Sciences, Lanzhou University, Lanzhou 730000, China
    Aquat Toxicol 140:117-22. 2013
    ..Taken together, this is the first study that has identified that 2,4-DCP exposure induced apoptosis through the mitochondria-dependent pathway in primary hepatocytes of grass carp. ..
  52. ncbi request reprint In vivo detection of metabolic changes by 1H-MRS in the DEN-induced hepatocellular carcinoma in Wistar rat
    Wei Dong Zhao
    Department of Radiology, Zhongshan Hospital, Shanghai Medical School, Fudan University, Shanghai, China, 200032
    J Cancer Res Clin Oncol 131:597-602. 2005
    ..To investigate the serial changes of the hepatic metabolites in a chemical-induced rat model of hepatocellular carcinoma (HCC) in vivo by a clinical 1.5 T MR scanner...
  53. doi request reprint Lymph node metastasis between sternocleidomastoid and sternohyoid muscle in clinically node-positive papillary thyroid carcinoma
    Guohua Sun
    Department of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai, China
    Head Neck 35:1168-70. 2013
    ..Therefore, our objective was to investigate the significance of LNSS metastasis...
  54. pmc Adjuvant chemotherapy, with or without taxanes, in early or operable breast cancer: a meta-analysis of 19 randomized trials with 30698 patients
    Ying Yi Qin
    Department of Health Statistics, Second Military Medical University, Shanghai, China
    PLoS ONE 6:e26946. 2011
    ..We investigated disease-free survival (DFS), overall survival (OS), and drug-related toxicities of taxanes by a systematic review and meta-analysis...
  55. doi request reprint Alpha-fetoprotein: a new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines
    Mengsen Li
    Key Laboratory of Molecular Biology, Hainan Medical College, Haikou, Hainan, China
    Int J Cancer 128:524-32. 2011
    ..In conclusion, these results demonstrate that cytoplasmic AFP is involved in regulation of hepatocellular growth and tumorigenesis...
  56. doi request reprint Gut SCP is an immune-relevant molecule involved in the primary immunological memory or pattern recognition in the amphioxus Branchiostoma belcheri
    Zhen Hong Zhuang
    Department of Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian 361005, People s Republic of China
    Fish Shellfish Immunol 30:700-5. 2011
    ..These results indicate that gut SCP is an immune-relevant molecule involved in the primary immunological memory or pattern recognition in the amphioxus Branchiostoma belcheri...
  57. doi request reprint Aspirin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity in primary midbrain cultures
    Fang Wang
    Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 1277 Jiefang Avenue, Wuhan, Hubei, China
    J Mol Neurosci 46:153-61. 2012
    ..These results suggest that ASA protects DA neurodegeneration by inhibiting the microglial-mediated oxidative stress/inflammatory response and by regulating the production of anti-inflammatory cytokines...
  58. ncbi request reprint Inhibiting tumor-cell growth by novel truncated staphylococcal enterotoxin C2 mutant
    Jing Hui
    Laboratory of Biomaterials and Biopharmaceuticals, School of Life Sciences, Liaoning University, Shenyang 110036, China
    Sheng Wu Gong Cheng Xue Bao 27:891-9. 2011
    ..It will become novel anti-tumor agents with the lowest side-effects and best treatment effects in clinic...
  59. doi request reprint A novel protocol for three-dimensional reconstruction of pharyngeal airway on computed tomography
    Rui Zhang
    Shanghai Key Laboratory of Stomatology, Shanghai, China
    J Craniofac Surg 24:1215-20. 2013
    ....
  60. ncbi request reprint Responses of ecosystem carbon cycle to experimental warming: a meta-analysis
    Meng Lu
    Coastal Ecosystems Research Station of the Yangtze River Estuary, Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Institute of Biodiversity Science, Fudan University, 220 Handan Road, Shanghai 200433 China
    Ecology 94:726-38. 2013
    ..Our results are also potentially useful for parameterizing and benchmarking land surface models in terms of C cycle responses to climate warming...
  61. doi request reprint Comment on "Phonemic diversity supports a serial founder effect model of language expansion from Africa"
    Chuan Chao Wang
    Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, and Department of Chinese Language and Literature, Fudan University, Shanghai 200433, China
    Science 335:657; author reply 657. 2012
    ..However, his claim was only supported when the phonemic diversities were binned into three or five levels. Analyses using raw data without simplification suggest a decline from central Asia rather than from Africa...
  62. doi request reprint A mild and efficient synthesis of monofluorinated α-lactam pseudopeptides via a novel dehydrofluorination of Ugi products
    Nianjin Liu
    Shanghai Key Laboratory of Chemical Biology, Center of Fluorine Chemical Technology, School of Pharmacy, East China University of Science and Technology, 200237, Shanghai, China
    Mol Divers 14:501-6. 2010
    ....
  63. ncbi request reprint Molecular analysis of the bacterial community in a continental high-temperature and water-flooded petroleum reservoir
    Hui Li
    Institute of Applied Chemistry, East China University of Science and Technology, Shanghai, China
    FEMS Microbiol Lett 257:92-8. 2006
    ..This work provides significant information on the structure of bacterial communities in high-temperature, long-term water-flooded petroleum reservoirs...
  64. doi request reprint Measurements of normal upper airway assessed by 3-dimensional computed tomography in Chinese children and adolescents
    Hui Li
    Department of Oral and Maxillofacial Surgery, College of Stomatology, Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China
    Int J Pediatr Otorhinolaryngol 75:1240-6. 2011
    ..To establish normative data of upper airway dimensions in Chinese children and adolescents by age and sex...