Emmanuel D Levy

Summary

Publications

  1. doi request reprint A simple definition of structural regions in proteins and its use in analyzing interface evolution
    Emmanuel D Levy
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    J Mol Biol 403:660-70. 2010
  2. pmc Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information
    Emmanuel D Levy
    Departement de Biochimie, Universite de Montreal, Montreal, Quebec, Canada
    Philos Trans R Soc Lond B Biol Sci 367:2594-606. 2012
  3. pmc CORRIE: enzyme sequence annotation with confidence estimates
    Benjamin Audit
    Laboratoire Joliot Curie and Laboratoire de Physique, CNRS UMR5672, Ecole Normale Superieure, Lyon Cedex 07, France
    BMC Bioinformatics 8:S3. 2007
  4. doi request reprint Systemizing the structures and structuring the system
    Emmanuel D Levy
    Universite de Montreal, Succ Centre, Ville, Montreal, Quebec, Canada
    Expert Rev Proteomics 7:319-22. 2010
  5. doi request reprint Weak functional constraints on phosphoproteomes
    Christian R Landry
    Centre Robert Cedergren, Bio Informatique et Génomique, Departement de Biochimie, C P 6128, Succ Centre Ville, Montreal, Quebec H3C 3J7, Canada
    Trends Genet 25:193-7. 2009
  6. pmc Molecular characterization of the evolution of phagosomes
    Jonathan Boulais
    Departement de pathologie et biologie cellulaire, Universite de Montreal, Montreal, Quebec, Canada
    Mol Syst Biol 6:423. 2010
  7. doi request reprint How perfect can protein interactomes be?
    Emmanuel D Levy
    Universite de Montreal, Montreal, Quebec, Canada
    Sci Signal 2:pe11. 2009
  8. doi request reprint Homomeric protein complexes: evolution and assembly
    A J Venkatakrishnan
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Biochem Soc Trans 38:879-82. 2010
  9. pmc Assembly reflects evolution of protein complexes
    Emmanuel D Levy
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nature 453:1262-5. 2008
  10. doi request reprint Evolution and dynamics of protein interactions and networks
    Emmanuel D Levy
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Curr Opin Struct Biol 18:349-57. 2008

Collaborators

Detail Information

Publications10

  1. doi request reprint A simple definition of structural regions in proteins and its use in analyzing interface evolution
    Emmanuel D Levy
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    J Mol Biol 403:660-70. 2010
    ..This analysis and conclusions will help understand the notion of promiscuity in protein-protein interaction networks...
  2. pmc Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information
    Emmanuel D Levy
    Departement de Biochimie, Universite de Montreal, Montreal, Quebec, Canada
    Philos Trans R Soc Lond B Biol Sci 367:2594-606. 2012
    ..Finally, we provide a model of functional and noisy or 'accidental' phosphorylation that explains these observations...
  3. pmc CORRIE: enzyme sequence annotation with confidence estimates
    Benjamin Audit
    Laboratoire Joliot Curie and Laboratoire de Physique, CNRS UMR5672, Ecole Normale Superieure, Lyon Cedex 07, France
    BMC Bioinformatics 8:S3. 2007
    ..The CORRIE server is available at: http://www.genomes.org/services/corrie/...
  4. doi request reprint Systemizing the structures and structuring the system
    Emmanuel D Levy
    Universite de Montreal, Succ Centre, Ville, Montreal, Quebec, Canada
    Expert Rev Proteomics 7:319-22. 2010
    ..In two other sections, we report studies that aim at charting and analyzing cellular systems, and finally we discuss talks that pointed to the issue of promiscuity in biological networks...
  5. doi request reprint Weak functional constraints on phosphoproteomes
    Christian R Landry
    Centre Robert Cedergren, Bio Informatique et Génomique, Departement de Biochimie, C P 6128, Succ Centre Ville, Montreal, Quebec H3C 3J7, Canada
    Trends Genet 25:193-7. 2009
    ..Our findings highlight the need to use evolutionary information to identify functional regulatory features such as post-translational modifications of eukaryotic proteomes...
  6. pmc Molecular characterization of the evolution of phagosomes
    Jonathan Boulais
    Departement de pathologie et biologie cellulaire, Universite de Montreal, Montreal, Quebec, Canada
    Mol Syst Biol 6:423. 2010
    ..Our work thus provides the first thorough analysis of the changes that enabled the transformation of the phagosome from a phagotrophic compartment into an organelle fully competent for antigen presentation...
  7. doi request reprint How perfect can protein interactomes be?
    Emmanuel D Levy
    Universite de Montreal, Montreal, Quebec, Canada
    Sci Signal 2:pe11. 2009
    ..Finally, we propose experimental strategies to estimate the fraction of evolutionary noise in PPI networks...
  8. doi request reprint Homomeric protein complexes: evolution and assembly
    A J Venkatakrishnan
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Biochem Soc Trans 38:879-82. 2010
    ..Also, we briefly discuss the pathway of their assembly in solution...
  9. pmc Assembly reflects evolution of protein complexes
    Emmanuel D Levy
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nature 453:1262-5. 2008
    ..Our model of self-assembly allows reliable prediction of evolution and assembly of a complex solely from its crystal structure...
  10. doi request reprint Evolution and dynamics of protein interactions and networks
    Emmanuel D Levy
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK
    Curr Opin Struct Biol 18:349-57. 2008
    ..Finally, we discuss recently developed methods that will improve this picture in the future...