Edward A Levine

Summary

Publications

  1. doi request reprint Race and recurrence in women who undergo neoadjuvant chemotherapy for breast cancer
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Am J Surg 205:397-401. 2013
  2. pmc Outcomes of patients with esophageal cancer staged with [¹⁸F]fluorodeoxyglucose positron emission tomography (FDG-PET): can postchemoradiotherapy FDG-PET predict the utility of resection?
    Arta Monir Monjazeb
    Wake Forest University Health Sciences, Winston Salem, NC 27103, USA
    J Clin Oncol 28:4714-21. 2010
  3. ncbi request reprint Survival and health outcomes after cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of appendiceal origin
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157 1082, USA
    Ann Surg Oncol 15:125-33. 2008
  4. ncbi request reprint Monitoring health outcomes following cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University, School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 14:1105-13. 2007
  5. ncbi request reprint Optimal timing of systemic therapy in resectable colorectal liver metastases
    Chukwuemeka Ihemelandu
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 79:414-21. 2013
  6. ncbi request reprint Patterns of care analysis among women with ductal carcinoma in situ in North Carolina
    LeRon C Jackson
    Department of Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Am J Surg 195:164-9. 2008
  7. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: experience with 501 procedures
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Am Coll Surg 204:943-53; discussion 953-5. 2007
  8. ncbi request reprint Pathologic complete response may not represent the optimal surrogate for survival after preoperative therapy for esophageal cancer
    A William Blackstock
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Int J Gastrointest Cancer 37:7-14. 2006
  9. pmc Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer
    Beth O Van Emburgh
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Oncol Rep 19:1311-21. 2008
  10. pmc Survival and quality of life following cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colonic origin
    Adrienne R Hill
    Section of Hematology and Oncology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 18:3673-9. 2011

Collaborators

Detail Information

Publications68

  1. doi request reprint Race and recurrence in women who undergo neoadjuvant chemotherapy for breast cancer
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Am J Surg 205:397-401. 2013
    ..Black women can have worse outcomes than white women with breast cancer. We examined survival in black and white women who received neoadjuvant chemotherapy...
  2. pmc Outcomes of patients with esophageal cancer staged with [¹⁸F]fluorodeoxyglucose positron emission tomography (FDG-PET): can postchemoradiotherapy FDG-PET predict the utility of resection?
    Arta Monir Monjazeb
    Wake Forest University Health Sciences, Winston Salem, NC 27103, USA
    J Clin Oncol 28:4714-21. 2010
    ..To determine whether [(18)F]fluorodeoxyglucose positron emission tomography (FDG-PET) can delineate patients with esophageal cancer who may not benefit from esophagectomy after chemoradiotherapy...
  3. ncbi request reprint Survival and health outcomes after cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for disseminated peritoneal cancer of appendiceal origin
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157 1082, USA
    Ann Surg Oncol 15:125-33. 2008
    ..This aggressive therapy may impair patient quality of life (QOL). The purpose of this study was to monitor health outcomes before and after treatment...
  4. ncbi request reprint Monitoring health outcomes following cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, Wake Forest University, School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 14:1105-13. 2007
    ..It is associated with physical and psychological morbidity. The purpose of this study was to monitor health outcomes related to treatment...
  5. ncbi request reprint Optimal timing of systemic therapy in resectable colorectal liver metastases
    Chukwuemeka Ihemelandu
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 79:414-21. 2013
    ..Adjuvant only systemic therapy was associated with an improved survival in resectable CLM. Prospective randomized trials are needed to confirm these findings...
  6. ncbi request reprint Patterns of care analysis among women with ductal carcinoma in situ in North Carolina
    LeRon C Jackson
    Department of Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Am J Surg 195:164-9. 2008
    ..Further study goals included the identification of predictors of breast-conserving surgery (BCS), adjuvant radiation, and/or hormonal therapy, as well as breast reconstruction after mastectomy...
  7. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: experience with 501 procedures
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Am Coll Surg 204:943-53; discussion 953-5. 2007
    ..We have been using aggressive cytoreductive surgery with intraperitoneal hyperthermic chemotherapy (IPHC) to treat PSD. The purpose of this article was to review our experience with IPHC...
  8. ncbi request reprint Pathologic complete response may not represent the optimal surrogate for survival after preoperative therapy for esophageal cancer
    A William Blackstock
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Int J Gastrointest Cancer 37:7-14. 2006
    ..We designed a phase II trial to examine the benefit of preoperative hyperfractionated radiation therapy (XRT) and concurrent chemotherapy for patients with locally advanced esophageal cancer (LAEC)...
  9. pmc Polymorphisms in CYP1B1, GSTM1, GSTT1 and GSTP1, and susceptibility to breast cancer
    Beth O Van Emburgh
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Oncol Rep 19:1311-21. 2008
    ..97; 95% CI=1.27-12.40). These results suggest the importance of estrogen/carcinogen metabolic enzymes in the etiology of breast cancer, especially in women before the age of 60, as well as preventative measures such as smoking cessation...
  10. pmc Survival and quality of life following cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colonic origin
    Adrienne R Hill
    Section of Hematology and Oncology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 18:3673-9. 2011
    ..Cytoreductive surgery (CS) with hyperthermic intraperitoneal chemotherapy (HIPEC) offers patients the prospect of long-term survival with alleviation of symptoms...
  11. doi request reprint Outcomes of immediate breast reconstruction in patients undergoing single-stage sentinel lymph node biopsy and mastectomy
    Benjamin C Wood
    Department of Plastic and Reconstructive Surgery, Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
    Ann Plast Surg 66:564-7. 2011
    ..We advocate that SLNB be performed in a single stage with mastectomy and IBR...
  12. ncbi request reprint Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy with mitomycin C for peritoneal carcinomatosis from nonappendiceal colorectal carcinoma
    Perry Shen
    Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 11:178-86. 2004
    ..We reviewed our experience using this approach for nonappendiceal colorectal cancer (NACC)...
  13. pmc Predictive value of 18-fluoro-deoxy-glucose-positron emission tomography (18F-FDG-PET) in the identification of responders to chemoradiation therapy for the treatment of locally advanced esophageal cancer
    Edward A Levine
    Surgical Oncology Service and the Department of General Surgery, Comprehensive Cancer Center of Wake Forest University, Winston Salem, NC 27157, USA
    Ann Surg 243:472-8. 2006
    ..To evaluate the utility of F-FDG-PET in predicting response to concomitant chemoradiation in locally-advanced esophageal cancer...
  14. doi request reprint Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal carcinomatosis from rectal cancer
    Konstantinos I Votanopoulos
    Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 20:1088-92. 2013
    ..Yet the efficacy of HIPEC in rectal patients is controversial because of the retroperitoneal location of the primary tumor. Therefore, we reviewed our experience in patients with PC from a rectal primary tumor...
  15. ncbi request reprint Impact of sentinel lymph node biopsy on immediate breast reconstruction after mastectomy
    Benjamin C Wood
    Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 75:551-6; discussion 556-7. 2009
    ....
  16. pmc A phase I trial of oxaliplatin for intraperitoneal hyperthermic chemoperfusion for the treatment of peritoneal surface dissemination from colorectal and appendiceal cancers
    John H Stewart
    Department of General Surgery, Surgical Oncology Service, Medical Center Blvd, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Ann Surg Oncol 15:2137-45. 2008
    ..Therefore, we undertook a phase I evaluation of IPHC with oxaliplatin for peritoneal dissemination from colorectal and appendiceal cancers to establish the dose-limiting toxicity (DLT) and the maximum tolerated dose (MTD)...
  17. ncbi request reprint Intraoperative evaluation of sentinel lymph nodes for metastatic melanoma by imprint cytology
    Victoria Soo
    Surgical Oncology Service and Department of Surgery, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, North Carolina 27157, USA
    Ann Surg Oncol 14:1612-7. 2007
    ..There is a paucity of literature on intraoperative imprint cytology (IIC) evaluation of the SLN in melanoma. The purpose of this article is to present an update to our experience with IIC for SLN in melanoma...
  18. doi request reprint Peritoneal surface disease from colorectal cancer: comparison with the hepatic metastases surgical paradigm in optimally resected patients
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Ann Surg Oncol 15:3422-32. 2008
    ..We examined our experience with cytoreductive surgery (CS) and intraperitoneal hyperthermic chemotherapy (IPHC) for peritoneal surface disease (PSD) compared with liver resection for HM...
  19. doi request reprint Outcomes associated with cytoreductive surgery and intraperitoneal hyperthermic chemotherapy in colorectal cancer patients with peritoneal surface disease and hepatic metastases
    Oliver Varban
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Cancer 115:3427-36. 2009
    ..The purpose of the current study was to compare the overall survival of patients with HM to those without and to examine predictive factors...
  20. doi request reprint Cytoreductive surgery with intraperitoneal hyperthermic chemotherapy for malignant peritoneal mesothelioma: mitomycin versus cisplatin
    Aaron U Blackham
    Surgical Oncology Service, Wake Forest University Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 17:2720-7. 2010
    ..The most efficacious chemotherapy regimen is not established. Herein we report clinical outcomes of MPM patients treated with CS and IPHC and contrast results using two chemoperfusates: mitomycin and cisplatin...
  21. doi request reprint Outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal surface dissemination from ovarian neoplasms
    E Nicole Parson
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Surg 202:481-6. 2011
    ..This work represents a review of the authors' institution's experience with HIPEC for PSD from OC...
  22. doi request reprint A comparison of hematologic toxicity profiles after heated intraperitoneal chemotherapy with oxaliplatin and mitomycin C
    Konstantinos Votanopoulos
    Department of General Surgery, Surgical Oncology Section, Wake Forest School of Medicine, Winston Salem, North Carolina
    J Surg Res 179:e133-9. 2013
    ..Our goal in this study is to present a single institution's experience with the hematologic toxicities of the two agents...
  23. doi request reprint Outcomes of repeat cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for the treatment of peritoneal surface malignancy
    Konstantinos I Votanopoulos
    Surgical Oncology Service, Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC 27157, USA
    J Am Coll Surg 215:412-7. 2012
    ..Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has improved the survival of patients with peritoneal surface malignancy. On recurrence, a repeat CRS/HIPEC is a treatment option...
  24. ncbi request reprint Sentinel lymph node mapping for gastric adenocarcinoma
    Robert D Becher
    Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27010, USA
    Am Surg 75:710-4. 2009
    ..Additionally, our study shows no utility in identifying micrometastatic disease with immunohistochemical techniques. Although a promising modality, we do not recommend the clinical use of SLN mapping for gastric cancer...
  25. ncbi request reprint Long-term survivorship and quality of life after cytoreductive surgery plus intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis
    Richard P McQuellon
    Department of Internal Medicine, Section of Hematology and Oncology, The Surgical Oncology Service, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Ann Surg Oncol 10:155-62. 2003
    ..The purpose of this study was to measure the quality of life (QOL) of survivors (>3 years) after treatment...
  26. ncbi request reprint Does shave biopsy accurately predict the final breslow depth of primary cutaneous melanoma?
    Phillip Moore
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am Surg 75:369-73; discussion 374. 2009
    ..SB is a valuable tool for practitioners in the diagnosis of melanoma. Nevertheless, patients diagnosed with melanoma by SB should be counseled about the rare need for additional surgery...
  27. ncbi request reprint Use of FDG-PET imaging for patients with disseminated cancer of the appendix
    Payam Rohani
    Surgical Oncology Service, Department of General Surgery, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Am Surg 76:1338-44. 2010
    ..PET imaging has limited use for patients with PDA. We do not recommend the use of FDG-PET for patients with PDA from cancer of the appendix...
  28. ncbi request reprint Intraoperative imprint cytology for evaluation of sentinel lymph nodes from Merkel cell carcinoma
    S Lindsey Wong
    Department of General Surgery Surgical Oncology Service, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 75:615-9. 2009
    ..SLN mapping has usefulness in patients with MCC. IIC is feasible and accurate in evaluating the SLN. IIC is a practical diagnostic tool when intraoperative analysis of SLN biopsy is desired for MCC...
  29. ncbi request reprint Use of sentinel lymph node biopsy for melanoma of the head and neck
    Lauren A Kilpatrick
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 73:754-8; discussion 758-9. 2007
    ..However, rates of nodal positivity are similar to melanoma of the trunk and extremities. Therefore, despite being more demanding, SLN is useful in diagnosis and treatment of melanomas of the head and neck...
  30. pmc Is intraoperative imprint cytology evaluation still feasible for the evaluation of sentinel lymph nodes for lobular carcinoma of the breast?
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest Baptist Medical Center, Winston Salem, NC, USA
    Ann Surg Oncol 19:929-34. 2012
    ..Intraoperative imprint cytology (IIC) is a rapid, reliable method for evaluating SLNs intraoperatively. We sought to reexamine our experience with this technique in the identification of invasive lobular breast cancer SLN metastases...
  31. ncbi request reprint Appendiceal neoplasms with peritoneal dissemination: outcomes after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy
    John H Stewart
    Department of General Surgery, Surgical Oncology Service, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, North Carolina 27157, USA
    Ann Surg Oncol 13:624-34. 2006
    ..Few data have correlated outcome with appendiceal histology after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy (IPHC). We have reviewed our experience with cytoreductive surgery and IPHC for PD from the appendix...
  32. pmc Patient rated outcomes and survivorship following cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CS + HIPEC)
    Katharine E Duckworth
    Internal Medicine, Wake Forest Baptist Health, Winston Salem, North Carolina 27157, USA
    J Surg Oncol 106:376-80. 2012
    ..The purpose of this study was to record patient rated outcomes and the HRQOL of long-term survivors...
  33. pmc Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes
    Edward A Levine
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, NC 27157, USA
    J Am Coll Surg 214:599-606; discussion 606-7. 2012
    ..This study uses gene expression analysis of peritoneal metastases to better understand these neoplasms...
  34. ncbi request reprint Recurrence after mastectomy for ductal carcinoma in situ
    Laura N Godat
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 75:592-5; discussion 595-7. 2009
    ..We recommend SLN biopsy without intraoperative touch prep analysis. Additional treatment may not be required in patients with microinvasion, positive or close margins because our series shows no local recurrence in these patients...
  35. ncbi request reprint Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from small bowel adenocarcinoma
    Yankai Sun
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Am Surg 79:644-8. 2013
    ..However, even with such advancement in management, treatment for small bowel adenocarcinoma still remains a challenge...
  36. doi request reprint Sentinel lymph node intraoperative imprint cytology in patients with breast cancer-costly or cost effective?
    Jan P Kamiński
    Department of Surgical Oncology, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 17:2920-5. 2010
    ..Thus, a positive IIC can spare the patient a second operation and the charges associated with it. The aim of this study is to assess the cost effectiveness of IIC in breast cancer patients...
  37. ncbi request reprint Pseudomyxoma peritonei of appendiceal origin: a clinicopathologic analysis of 101 patients uniformly treated at a single institution, with literature review
    Robert F Bradley
    Department of Pathology, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Am J Surg Pathol 30:551-9. 2006
    ..Cases that are moderately differentiated to poorly differentiated are classified as mucinous carcinoma peritonei-high grade...
  38. doi request reprint Restorative yoga for women with breast cancer: findings from a randomized pilot study
    Suzanne C Danhauer
    Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157 1082, USA
    Psychooncology 18:360-8. 2009
    ..Study goals were: to determine the feasibility of implementing a RY intervention for women with breast cancer; and to examine group differences in self-reported emotional, health-related quality of life, and symptom outcomes...
  39. pmc Management of peritoneal carcinomatosis from colorectal cancer
    Chukwuemeka U Ihemelandu
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Semin Oncol 38:568-75. 2011
    ..This review will examine recent evidence pertaining to the evolving surgical oncology paradigm for management of colorectal peritoneal carcinomatosis...
  40. ncbi request reprint Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy in peritoneal sarcomatosis
    Reese W Randle
    Surgical Oncology Service in the Department of General Surgery, Wake Forest University, Winston Salem, North Carolina, USA
    Am Surg 79:620-4. 2013
    ..Although a complete cytoreduction is related to improved survival, the role of HIPEC in these patients is unknown. A multi-institutional review will help define the role of CRS-HIPEC in this population...
  41. pmc Polymorphisms in drug metabolism genes, smoking, and p53 mutations in breast cancer
    Beth O Van Emburgh
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Mol Carcinog 47:88-99. 2008
    ....
  42. ncbi request reprint A prospective evaluation of the impact of 18-F-fluoro-deoxy-D-glucose positron emission tomography staging on survival for patients with locally advanced esophageal cancer
    A William Blackstock
    Department of Radiation Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Int J Radiat Oncol Biol Phys 64:455-60. 2006
    ..To determine the impact of 18-F-fluoro-deoxy-D-glucose positron emission tomography (FDG-PET) in the staging and prognosis of patients with locally advanced esophageal cancer (LAEC)...
  43. ncbi request reprint Outcome after mastectomy for ipsilateral breast tumor recurrence after breast conserving surgery
    H Randall Beard
    Surgical Oncology Service of Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 76:829-34. 2010
    ..Mastectomy for IBTR remains effective treatment for most patients, but the risk of PMR remains. Patients with IBTR tumors >2 cm have an increased risk of PMR. Strict follow-up should be routine, especially during the first 24 months...
  44. ncbi request reprint Pleuropulmonary involvement in pseudomyxoma peritonei: morphologic assessment and literature review
    Kim R Geisinger
    Department of Pathology, Wake Forest University School of Medicine and the North Carolina Baptist Hospital, Winston Salem, NC 27157 1072, USA
    Am J Clin Pathol 127:135-43. 2007
    ..The smear backgrounds contained wispy mucin. None of the 5 patients developed thoracic lymph nodal metastases. Although rare, mucinous neoplasms from PP may involve the thorax...
  45. doi request reprint Current status and future directions in appendiceal cancer with peritoneal dissemination
    Konstantinos I Votanopoulos
    Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Surg Oncol Clin N Am 21:599-609. 2012
    ..Finally, future challenges for the use of hyperthermic intraperitoneal perfusion for appendiceal primary tumors are explored...
  46. doi request reprint Metastases of colorectal cancer to the liver and peritoneum: comparison of surgical paradigms
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 8:1797-808. 2008
    ..This review will examine recent evidence regarding these two surgical oncology paradigms and compare patient populations, clinical outcomes and future challenges...
  47. doi request reprint Intraperitoneal hyperthermic chemotherapy: an evolving paradigm for the treatment of peritoneal surface malignancies
    John H Stewart
    Surgical Oncology Service, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 8:1809-18. 2008
    ..The present review will outline the rationale, current practice and future directions of IPHC in the management of peritoneal surface malignancies...
  48. doi request reprint Outcomes of Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients Older Than 70 Years; Survival Benefit at Considerable Morbidity and Mortality
    Konstantinos I Votanopoulos
    Surgical Oncology Service, Department of General Surgery, Wake Forest University, Winston Salem, NC, USA
    Ann Surg Oncol 20:3497-503. 2013
    ..Yet, for elderly patients (older than 70 years of age) CRS/HIPEC is controversial, due to associated morbidity...
  49. doi request reprint Predicting Postoperative Morbidity Following Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CS+HIPEC) with Preoperative FACT-C (Functional Assessment of Cancer Therapy) and Patient-Rated Performance Status
    Chukwuemeka U Ihemelandu
    Section of Surgical Oncology, Department of General Surgery, Wake Forest School of Medicine, Winston Salem, NC, USA
    Ann Surg Oncol 20:3519-26. 2013
    ..One goal of our ongoing patient-reported health-related quality of life (HRQoL) program is to describe the prognostic value of HRQoL measures for predicting postoperative morbidity and mortality following CS+HIPEC...
  50. ncbi request reprint Intraperitoneal hyperthermic chemotherapy using carboplatin: a phase I analysis in ovarian carcinoma
    Samuel S Lentz
    Section on Gynecologic Oncology, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Gynecol Oncol 106:207-10. 2007
    ....
  51. doi request reprint Adenocarcinoma of the appendix is rarely detected by colonoscopy
    Apurva N Trivedi
    Section of Gastroenterology, Wake Forest University Baptist Medical Center, Medical Center Blvd, Winston Salem, NC 27157, USA
    J Gastrointest Surg 13:668-75. 2009
    ..The aim of this study is to determine the diagnostic yield of colonoscopy in detecting appendiceal lesions in patients with appendiceal adenocarcinoma and pseudomyxoma peritonei...
  52. ncbi request reprint Initial institutional experience with thoracoscopic assisted esophagectomy
    Adrian L Lata
    Department of Thoracic, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Am Surg 76:735-40. 2010
    ..8% in TAE vs. 50% in OE group), but the in-hospital mortality was reduced with TAE (7.1% with TAE vs. 16.7% with OE). TAE is feasible with a low conversion rate, acceptable morbidity, and low mortality...
  53. ncbi request reprint Breast cancer reconstruction in the elderly
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest University Baptist Medical Center, Winston Salem, North Carolina 27157, USA
    Am Surg 77:1640-3. 2011
    ..One local skin recurrence was treated with removal of implant and skin resection. Two patients have died from metastatic disease. Age should not be a contraindication for breast reconstruction in elderly women...
  54. ncbi request reprint Intraoperative imprint cytology for evaluation of sentinel lymph nodes from visceral malignancies
    Edward A Levine
    Surgical Oncology Service, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Gastrointest Surg 7:687-91. 2003
    ..If there is a negative result, the technique may miss disease that is present on subsequent permanent sections. We do not recommend routine use of IIC; however, it may be of use in clinical trials...
  55. ncbi request reprint Pathologic correlation study of microwave coagulation therapy for hepatic malignancies using a three-ring probe
    Perry Shen
    Department of General Surgery, Surgical Oncology Section, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA
    J Gastrointest Surg 11:603-11. 2007
    ..The ablation time is significantly shorter than other available ablative techniques. Immediate histologic exam produces some evidence of coagulative necrosis. Further study of this promising technology is warranted...
  56. doi request reprint Outcome analysis of 541 women undergoing breast conservation therapy
    David A Kelly
    Department of Plastic Reconstructive Surgery, Wake Forest Baptist Health, Winston Salem, NC, USA
    Ann Plast Surg 68:435-7. 2012
    ..Integration of oncoplastic techniques in the surgical management of patients undergoing BCT would likely contribute to improvement in aesthetic outcomes and overall patient satisfaction...
  57. ncbi request reprint Positron emission mammography: initial clinical results
    Edward A Levine
    Department of Surgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Ann Surg Oncol 10:86-91. 2003
    ..Functional breast imaging coupled with mammography (positron emission mammography [PEM]) could improve imaging of such lesions. A prospective study was performed using PEM in women scheduled for stereotactic breast biopsy...
  58. ncbi request reprint DNA-repair genetic polymorphisms and breast cancer risk
    Tasha R Smith
    Department of Cancer Biology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Cancer Epidemiol Biomarkers Prev 12:1200-4. 2003
    ..We provide evidence that variants of XRCC1, XRCC3, and ERCC4/XPF genes, particularly in combination, contribute to breast cancer susceptibility...
  59. ncbi request reprint Survival disadvantage among Medicaid-insured breast cancer patients treated with breast conserving surgery without radiation therapy
    Kristie Long Foley
    Division of Public Health Sciences, Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Breast Cancer Res Treat 101:207-14. 2007
    ..It is possible that the prognostic significance of omission of RT in clinical trials underestimates the significance of risk in the community...
  60. ncbi request reprint Sentinel lymph node biopsy during pregnancy: initial clinical experience
    Matthew M Mondi
    Surgical Oncology Services, Wake Forest University, Winston Salem, North Carolina, USA
    Ann Surg Oncol 14:218-21. 2007
    ....
  61. doi request reprint Contralateral prophylactic mastectomy in breast cancer patients who test negative for BRCA mutations
    Marissa Howard-McNatt
    Department of Surgical Oncology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1096, USA
    Am J Surg 202:298-302. 2011
    ..Some women choose contralateral prophylactic mastectomy (CPM) at the time of their breast cancer diagnosis despite testing negative...
  62. doi request reprint Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for patients with peritoneal carcinomatosis secondary to urachal adenocarcinoma
    L Spencer Krane
    Department of Urology, Wake Forest University, Winston Salem, North Carolina, USA
    J Surg Oncol 105:258-60. 2012
    ..We describe our 18-year experience in managing these patients with cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC)...
  63. doi request reprint Role of bacillus Calmette-Guérin in the treatment of advanced melanoma
    John H Stewart
    Department of Surgery, Tumor Immunotherapy Program, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Expert Rev Anticancer Ther 11:1671-6. 2011
    ..The work contained herein will explore the clinical rationale for adjuvant BCG in future trials focused on the treatment of patients with advanced malignant melanoma...
  64. ncbi request reprint Cytomorphologic features of primary peritoneal mesothelioma in effusion, washing, and fine-needle aspiration biopsy specimens: examination of 49 cases at one institution, including post-intraperitoneal hyperthermic chemotherapy findings
    Nilesh P Patel
    The Department of Pathology, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Am J Clin Pathol 128:414-22. 2007
    ..To our knowledge, this is the first large series reporting the cytomorphologic features of PPM in peritoneal effusions, pelvic washing specimens, and infradiaphragmatic fine-needle aspiration biopsy specimens...
  65. ncbi request reprint Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors
    Gira N Raval
    Surgical Oncology and Vascular Surgery Services, Department of General Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Oncogene 22:6194-203. 2003
    ..Downregulation of TM1 in breast tumors may destabilize microfilament architecture and confer resistance to anoikis, which facilitates survival of neoplastic cells outside the normal microenvironment and promote malignant growth...
  66. ncbi request reprint Factors predicting survival after intraperitoneal hyperthermic chemotherapy with mitomycin C after cytoreductive surgery for patients with peritoneal carcinomatosis
    Perry Shen
    Wake Forest University Baptist Medical Center, Department of General Surgery, Winston Salem, NC 27157, USA
    Arch Surg 138:26-33. 2003
    ..Certain clinicopathologic factors predict improved survival after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal carcinomatosis...
  67. ncbi request reprint Participation in surgical oncology clinical trials: gender-, race/ethnicity-, and age-based disparities
    John H Stewart
    Department of General Surgery, Section on Surgical Oncology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Ann Surg Oncol 14:3328-34. 2007
    ..To characterize the representation of racial/ethnic minorities, women, and older persons among participants in surgical trials sponsored by the National Cancer Institute (NCI)...
  68. ncbi request reprint Male breast cancer during treatment with leuprolide for prostate cancer
    Joseph Yacoub
    Department of Radiation Oncology, Wake Forest University, Winston Salem, NC 27157, USA
    Clin Adv Hematol Oncol 5:555-6; discussion 556-7. 2007