Valerio Leoni

Summary

Publications

  1. Leoni V. The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease. Clin Chem Lab Med. 2011;49:375-83 pubmed publisher
    ..In the study of cognitive impaired patients and in their follow-up, biomarkers should be interpreted in consideration of the ApoE genotype in order to better predict the progression of the disease. ..
  2. Leoni V, Nury T, Vejux A, Zarrouk A, Caccia C, Debbabi M, et al. Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with ?-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, . J Steroid Biochem Mol Biol. 2017;169:96-110 pubmed publisher
    ..A better knowledge of mitochondrial associated dysfunctions triggered by 7KC will contribute to bring new information on the demyelination processes which are linked with oxidative stress and lipid peroxidation, especially in MS. ..
  3. Musman J, Paradis S, Panel M, Pons S, Barau C, Caccia C, et al. A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats. Biochem Pharmacol. 2017;142:87-95 pubmed publisher
    ..The inhibition of cholesterol accumulation with TSPO ligands represents an interesting strategy to protect the mitochondria during ischemia-reperfusion in hypercholesterolemic conditions. ..

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Detail Information

Publications3

  1. Leoni V. The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease. Clin Chem Lab Med. 2011;49:375-83 pubmed publisher
    ..In the study of cognitive impaired patients and in their follow-up, biomarkers should be interpreted in consideration of the ApoE genotype in order to better predict the progression of the disease. ..
  2. Leoni V, Nury T, Vejux A, Zarrouk A, Caccia C, Debbabi M, et al. Mitochondrial dysfunctions in 7-ketocholesterol-treated 158N oligodendrocytes without or with ?-tocopherol: Impacts on the cellular profil of tricarboxylic cycle-associated organic acids, long chain saturated and unsaturated fatty acids, oxysterols, . J Steroid Biochem Mol Biol. 2017;169:96-110 pubmed publisher
    ..A better knowledge of mitochondrial associated dysfunctions triggered by 7KC will contribute to bring new information on the demyelination processes which are linked with oxidative stress and lipid peroxidation, especially in MS. ..
  3. Musman J, Paradis S, Panel M, Pons S, Barau C, Caccia C, et al. A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats. Biochem Pharmacol. 2017;142:87-95 pubmed publisher
    ..The inhibition of cholesterol accumulation with TSPO ligands represents an interesting strategy to protect the mitochondria during ischemia-reperfusion in hypercholesterolemic conditions. ..