Francene J Lemoine

Summary

Publications

  1. pmc Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast
    Francene J Lemoine
    Department of Biological Sciences, Northwestern State University of Louisiana, Natchitoches, LA 71497, USA
    Mol Cell Biol 28:5359-68. 2008
  2. ncbi request reprint Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
    Francene J Lemoine
    Department of Biology and Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Cell 120:587-98. 2005
  3. ncbi request reprint Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    DNA Repair (Amst) 5:1010-20. 2006
  4. ncbi request reprint Damaged DNA and miscounted chromosomes: human T cell leukemia virus type I tax oncoprotein and genetic lesions in transformed cells
    Susan J Marriott
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
    J Biomed Sci 9:292-8. 2002
  5. pmc Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements
    Kelly VanHulle
    Biology Department, Indiana University Purdue University Indiana, 723 West Michigan Street, Indianapolis, IN 46202 5132, USA
    Mol Cell Biol 27:2601-14. 2007

Collaborators

Detail Information

Publications5

  1. pmc Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast
    Francene J Lemoine
    Department of Biological Sciences, Northwestern State University of Louisiana, Natchitoches, LA 71497, USA
    Mol Cell Biol 28:5359-68. 2008
    ..These findings demonstrate that a change in the stoichiometry of replicative DNA polymerases results in recombinogenic DNA lesions, presumably double-strand DNA breaks...
  2. ncbi request reprint Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites
    Francene J Lemoine
    Department of Biology and Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Cell 120:587-98. 2005
    ..We demonstrate that this pair of Ty elements constitutes a preferred site for double-strand DNA breaks when DNA replication is compromised, analogous to the fragile sites observed in mammalian chromosomes...
  3. ncbi request reprint Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae
    Piotr A Mieczkowski
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA
    DNA Repair (Amst) 5:1010-20. 2006
    ..Genome Res. 110 (2005) 70-90; D.J. Garfinkel, Genome evolution mediated by Ty elements in Saccharomyces, Cytogenet. Genome Res. 110 (2005) 63-69] that discuss genomic rearrangements involving Ty elements...
  4. ncbi request reprint Damaged DNA and miscounted chromosomes: human T cell leukemia virus type I tax oncoprotein and genetic lesions in transformed cells
    Susan J Marriott
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
    J Biomed Sci 9:292-8. 2002
    ..The consequences of these effects as well as the evolutionary advantage this may provide to HTLV-I are discussed...
  5. pmc Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements
    Kelly VanHulle
    Biology Department, Indiana University Purdue University Indiana, 723 West Michigan Street, Indianapolis, IN 46202 5132, USA
    Mol Cell Biol 27:2601-14. 2007
    ..This "SSA-GCR" pathway is likely to be important in the repair of isochromatid breaks resulting from collapsed replication forks, certain types of radiation, or telomere aberrations that mimic isochromatid breaks...