Christian Lehmann

Summary

Publications

  1. doi request reprint Microcirculation diagnostics and applied studies in circulatory shock - research from the bench to the bedside
    Christian Lehmann
    Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS, Canada
    Clin Hemorheol Microcirc 52:131-9. 2012
  2. ncbi request reprint Physostigmine reverses disturbances of the intestinal microcirculation during experimental endotoxemia
    Juan Zhou
    Department of Anesthesia, Dalhousie University, Halifax, NS, Canada
    Clin Hemorheol Microcirc 56:273-84. 2014
  3. doi request reprint Inhibition of endocannabinoid degradation in experimental endotoxemia reduces leukocyte adhesion and improves capillary perfusion in the gut
    Mandana Kianian
    Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada
    J Basic Clin Physiol Pharmacol 24:27-33. 2013
  4. pmc Oxidized LDL and LOX-1 in experimental sepsis
    Nadia Al-Banna
    Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University Halifax, Nova Scotia, Canada B3H 2Y9
    Mediators Inflamm 2013:761789. 2013
  5. pmc Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis
    Christian Lehmann
    Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada, B3H 2Y9
    Crit Care 16:R47. 2012
  6. ncbi request reprint Novel approaches to the development of anti-sepsis drugs
    Christian Lehmann
    Dalhousie University, Department of Anaesthesia, 10 West Victoria, 1276 South Park St, Halifax, Nova Scotia, B3H 2Y9, Canada 1 902 473 2331 1 902 423 9454
    Expert Opin Drug Discov 9:523-31. 2014
  7. doi request reprint Activated protein C improves pial microcirculation in experimental endotoxemia in rats
    Juan Zhou
    Department of Anesthesia, Dalhousie University, Halifax, NS, Canada
    Microvasc Res 83:276-80. 2012

Collaborators

  • Dragan Pavlovic
  • Brent Johnston
  • Michael Sander
  • Juan Zhou
  • Orlando Hung
  • Mandana Kianian
  • Nadia Al-Banna
  • Romesh Shukla
  • Sara Whynot
  • Vladimir Cerny
  • Alexander Spassov
  • Stefan Masur
  • Hartmut Kern
  • Johanna Rüb
  • Islam Saleh Abdo
  • Nadia A Al-Banna
  • Melanie E M Kelly
  • Julia Willecke
  • Michael Wendt
  • Claudius Friedel
  • Henry Schroeder

Detail Information

Publications7

  1. doi request reprint Microcirculation diagnostics and applied studies in circulatory shock - research from the bench to the bedside
    Christian Lehmann
    Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University, Halifax, NS, Canada
    Clin Hemorheol Microcirc 52:131-9. 2012
    ..Therefore, microcirculatory targets may represent the most important endpoints to optimize therapy of circulatory shock...
  2. ncbi request reprint Physostigmine reverses disturbances of the intestinal microcirculation during experimental endotoxemia
    Juan Zhou
    Department of Anesthesia, Dalhousie University, Halifax, NS, Canada
    Clin Hemorheol Microcirc 56:273-84. 2014
    ..In conclusion, physostigmine treatment significantly improved the intestinal microcirculation in experimental endotoxemia by reducing leukocyte adhesion and increasing FCD. ..
  3. doi request reprint Inhibition of endocannabinoid degradation in experimental endotoxemia reduces leukocyte adhesion and improves capillary perfusion in the gut
    Mandana Kianian
    Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada
    J Basic Clin Physiol Pharmacol 24:27-33. 2013
    ..Our study aimed to examine intestinal leukocyte adhesion and capillary perfusion following selective inhibition of the endocannabinoid degradation enzyme, fatty acid amide hydrolase (FAAH), in experimental sepsis (endotoxemia)...
  4. pmc Oxidized LDL and LOX-1 in experimental sepsis
    Nadia Al-Banna
    Department of Anesthesia, Pain Management and Perioperative Medicine, Dalhousie University Halifax, Nova Scotia, Canada B3H 2Y9
    Mediators Inflamm 2013:761789. 2013
    ..Modulation of LOX-1 response could be utilized for the treatment of local and systemic inflammation, but the successful use of this target requires further understanding of its broad effects. ..
  5. pmc Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis
    Christian Lehmann
    Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada, B3H 2Y9
    Crit Care 16:R47. 2012
    ..The aim of this study was therefore to investigate the effects of CB2R manipulation on leukocyte activation within the intestinal microcirculation in two acute experimental sepsis models...
  6. ncbi request reprint Novel approaches to the development of anti-sepsis drugs
    Christian Lehmann
    Dalhousie University, Department of Anaesthesia, 10 West Victoria, 1276 South Park St, Halifax, Nova Scotia, B3H 2Y9, Canada 1 902 473 2331 1 902 423 9454
    Expert Opin Drug Discov 9:523-31. 2014
    ..Increasing incidence and high mortality of sepsis require novel approaches for the development of anti-sepsis drugs...
  7. doi request reprint Activated protein C improves pial microcirculation in experimental endotoxemia in rats
    Juan Zhou
    Department of Anesthesia, Dalhousie University, Halifax, NS, Canada
    Microvasc Res 83:276-80. 2012
    ..Our hypothesis is rhAPC protects pial microcirculation in endotoxemia...