Lee S, Lee W, Bae J, Ma E. Synthesis and in Vitro and in Vivo Anticoagulant and Antiplatelet Activities of Amidino- and Non-Amidinobenzamides. Molecules. 2016;21: pubmed publisher
..Collectively, 1 and 2 possess some antiplatelet and anticoagulant activities and offer a basis for development of a novel antithrombotic product. ..
Lee S, Lee W, Nguyen T, Um I, Bae J, Ma E. Synthesis and Thrombin, Factor Xa and U46619 Inhibitory Effects of Non-Amidino and Amidino NÂ²-Thiophenecarbonyl- and NÂ²-Tosylanthranilamides. Int J Mol Sci. 2017;18: pubmed publisher
..Among the derivatives evaluated, N-(3'-amidinophenyl)-2-((thiophen-2''-yl)carbonylamino)benzamide (21) was the most active compound. ..