R Mahfouz

Summary

Affiliation: American University of Beirut
Country: Lebanon

Publications

  1. Assaf N, El Cheikh J, Bazarbachi A, Salem Z, Farra C, Chakhachiro Z, et al. Molecular profiling of adult acute myeloid and lymphoid leukemia in a major referral center in Lebanon: a 10-year experience report and review of the literature. Mol Biol Rep. 2019;46:2003-2011 pubmed publisher
    ..This study will be a baseline reference for future research and epidemiological data useful for transplant centers and oncologists both in Lebanon and the region. ..
  2. Wex B, Safi R, Antonios G, Zgheib P, Awad D, Kobeissy F, et al. SLC35B4, an Inhibitor of Gluconeogenesis, Responds to Glucose Stimulation and Downregulates Hsp60 among Other Proteins in HepG2 Liver Cell Lines. Molecules. 2018;23: pubmed publisher
    ..The downstream cascade ultimately alters the ability of cultured liver cells to inhibit endogenous glucose production, and this could play a role in the association of the above-listed genes with the pathogenesis of diabetes. ..
  3. El Achi H, Awwad J, Abou Daya S, Halabi S, Damianos S, Mahfouz R. The association between cardiovascular disease gene mutations and recurrent pregnancy loss in the Lebanese population. Mol Biol Rep. 2018;45:911-916 pubmed publisher
    ..Moreover, a protective role of positive APO-E3 isoform was observed. This study is the first in the Lebanese population in associating RPL with a large panel of CVD related genes. ..
  4. request reprint
    Mahfouz R, Rayes R, Mahfoud Z, Bazarbachi A, Zaatari G. Distribution of killer cell immunoglobulin-like receptors genotypes in the Lebanese population. Tissue Antigens. 2006;68:66-71 pubmed
    ..3:1. The frequency of the KIR loci suggests that the Lebanese population shares common general features with the Caucasoid populations studied before, but still has its own unique decreased or increased frequencies of several loci. ..
  5. Mahfouz R, Sabbagh A, Shamseddine W, Bazarbachi A, Ibrahim G, Arayssi T, et al. Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever. Genet Test Mol Biomarkers. 2009;13:91-5 pubmed publisher
    ..This is the first report that describes the KIR genotypic profile in this important clinical disease. ..
  6. Mahfouz R, Halas H, Hoteit R, Saadeh M, Shamseddeen W, Charafeddine K, et al. Study of KIR genes in Lebanese patients with tuberculosis. Int J Tuberc Lung Dis. 2011;15:1688-91 pubmed publisher
    ..This confirms the findings of another unique international study performed in the Mexican population showing a greater repertoire of inhibitory KIR genes among TB patients than controls. ..
  7. Fakhruddin N, Jabbour M, Novy M, Tamim H, Bahmad H, Farhat F, et al. BRAF and NRAS Mutations in Papillary Thyroid Carcinoma and Concordance in BRAF Mutations Between Primary and Corresponding Lymph Node Metastases. Sci Rep. 2017;7:4666 pubmed publisher
    ..BRAF mutation is conserved in metastatic lymph node deposits, thus BRAF is an early mutational pathogenetic driver. Therefore, targeted therapy is potential in recurrent and advanced stage disease. ..