Benoit Le Goff

Summary

Publications

  1. doi request reprint Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis
    Benoit Le Goff
    Service de Rhumatologie, Hotel Dieu, 1, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France
    Joint Bone Spine 77:201-5. 2010
  2. ncbi request reprint Ultrasound assessment of the posterior sacroiliac ligaments
    Benoit Le Goff
    Hotel Dieu, Nantes University Hospital, Nantes, France
    Clin Exp Rheumatol 29:1014-7. 2011
  3. ncbi request reprint A comparison between bisphosphonates and other treatments for osteoporosis
    B Le Goff
    INSERM U957, Physiopathologie de la Resorption Osseuse et Therapie des Tumeurs Osseuses Primitives, Nantes, France
    Curr Pharm Des 16:3037-44. 2010
  4. ncbi request reprint Pharmacodynamics of bisphosphonates in arthritis
    Benoit Le Goff
    INSERM UMR S957, Physiopathologie de la Resorption Osseuse et Therapie des Tumeurs Osseuses Primitives, Faculte de Medecine, 1 rue Gaston Veil, 44035 Nantes cedex 1, France
    Expert Rev Clin Pharmacol 4:633-41. 2011
  5. pmc A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis
    Benoit Le Goff
    INSERM UMR S 957, 1 rue Gaston Veil, 44035, Nantes Cedex 1, France
    Arthritis Res Ther 11:R185. 2009
  6. doi request reprint Six-month response to anti-TNF drugs in axial spondylarthropathy according to the fulfillment or not of New-York criteria for ankylosing spondylitis or French recommendations for anti-TNF use. A "real life" retrospective study on 175 patients
    Stephanie Gerard
    Rheumatology Unit, Nantes University Hospital CHU Nantes, Place Alexis Ricordeau, 44093, Nantes Cedex 01, France
    Joint Bone Spine 75:680-7. 2008
  7. doi request reprint Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections
    Anne Blanchais
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Nantes Cedex 1, France
    Joint Bone Spine 77:440-4. 2010
  8. doi request reprint Outcome and safety of TNFα antagonist therapy in 475 consecutive outpatients (with rheumatoid arthritis or spondyloarthropathies) treated by a single physician according to their eligibility for clinical trials
    Jean Marie Berthelot
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, 44093 Nantes Cedex 01, France
    Joint Bone Spine 77:564-9. 2010
  9. doi request reprint Weekly home self-assessment of RAPID-4/3 scores in rheumatoid arthritis: a 6-month study in 26 patients
    Anne Blanchais
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, 44093 Nantes Cedex 01, France
    Joint Bone Spine 77:582-7. 2010
  10. doi request reprint Information on glucocorticoid therapy in the main studies of biological agents
    Vincent André
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Joint Bone Spine 78:478-83. 2011

Collaborators

Detail Information

Publications22

  1. doi request reprint Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis
    Benoit Le Goff
    Service de Rhumatologie, Hotel Dieu, 1, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France
    Joint Bone Spine 77:201-5. 2010
    ..Thus, in patients with RA, blocking IL-6 may be effective both in diminishing the inflammatory manifestations and in preventing the bone complications of the disease...
  2. ncbi request reprint Ultrasound assessment of the posterior sacroiliac ligaments
    Benoit Le Goff
    Hotel Dieu, Nantes University Hospital, Nantes, France
    Clin Exp Rheumatol 29:1014-7. 2011
    ..They are recognised as a potential source of aspecific low back pain or peripartum pelvic pain. The aim of this study was to assess the characteristics of these ligaments using high resolution ultrasonography (HRUS)...
  3. ncbi request reprint A comparison between bisphosphonates and other treatments for osteoporosis
    B Le Goff
    INSERM U957, Physiopathologie de la Resorption Osseuse et Therapie des Tumeurs Osseuses Primitives, Nantes, France
    Curr Pharm Des 16:3037-44. 2010
    ..This review gives an overview of the recent data on the efficacity and tolerance of bisphosphonates in the different forms of osteoporosis and compares them to the other treatments currently available...
  4. ncbi request reprint Pharmacodynamics of bisphosphonates in arthritis
    Benoit Le Goff
    INSERM UMR S957, Physiopathologie de la Resorption Osseuse et Therapie des Tumeurs Osseuses Primitives, Faculte de Medecine, 1 rue Gaston Veil, 44035 Nantes cedex 1, France
    Expert Rev Clin Pharmacol 4:633-41. 2011
    ..If their indication in the prevention of glucocorticoid-induced osteoporosis is clear, any beneficial effects on bone erosions are still controversial but interesting preliminary results warrant further investigations...
  5. pmc A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis
    Benoit Le Goff
    INSERM UMR S 957, 1 rue Gaston Veil, 44035, Nantes Cedex 1, France
    Arthritis Res Ther 11:R185. 2009
    ..We hypothesized that MTX and ZA could have an additive effect to prevent both bone erosion and systemic bone loss...
  6. doi request reprint Six-month response to anti-TNF drugs in axial spondylarthropathy according to the fulfillment or not of New-York criteria for ankylosing spondylitis or French recommendations for anti-TNF use. A "real life" retrospective study on 175 patients
    Stephanie Gerard
    Rheumatology Unit, Nantes University Hospital CHU Nantes, Place Alexis Ricordeau, 44093, Nantes Cedex 01, France
    Joint Bone Spine 75:680-7. 2008
    ....
  7. doi request reprint Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections
    Anne Blanchais
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Nantes Cedex 1, France
    Joint Bone Spine 77:440-4. 2010
    ..To assess the feasibility and safety of caudal epidural glucocorticoid injections performed with ultrasound guidance...
  8. doi request reprint Outcome and safety of TNFα antagonist therapy in 475 consecutive outpatients (with rheumatoid arthritis or spondyloarthropathies) treated by a single physician according to their eligibility for clinical trials
    Jean Marie Berthelot
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, 44093 Nantes Cedex 01, France
    Joint Bone Spine 77:564-9. 2010
    ....
  9. doi request reprint Weekly home self-assessment of RAPID-4/3 scores in rheumatoid arthritis: a 6-month study in 26 patients
    Anne Blanchais
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, 44093 Nantes Cedex 01, France
    Joint Bone Spine 77:582-7. 2010
    ....
  10. doi request reprint Information on glucocorticoid therapy in the main studies of biological agents
    Vincent André
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Joint Bone Spine 78:478-83. 2011
    ..To evaluate reported information on prednisone therapy in the main studies of biological agents used to treat rheumatoid arthritis (RA)...
  11. doi request reprint Osteoclasts in RA: diverse origins and functions
    Benoit Le Goff
    Service de Rhumatologie, Hotel Dieu, 1, Place Alexis Ricordeau, 44093 Nantes Cedex 1, France LUNAM Université, 44000 Nantes, France INSERM, UMR957, Physiopathologie de la Resorption Osseuse et Therapie des Tumeurs Osseuses Primitives, 44035 Nantes, France Université de NANTES, Nantes Atlantique Universites, 44035 Nantes, France Electronic address
    Joint Bone Spine 80:586-91. 2013
    ..Research into these interactions may identify new targets for treatments against the bone abnormalities associated with chronic inflammatory disease. ..
  12. doi request reprint Assessment of calcific tendonitis of rotator cuff by ultrasonography: comparison between symptomatic and asymptomatic shoulders
    Benoit Le Goff
    Rheumatology Unit, Hotel Dieu, Nantes University Hospital, Nantes, France
    Joint Bone Spine 77:258-63. 2010
    ..We looked for differences on ultrasound (US) and power Doppler findings between symptomatic and asymptomatic cases of shoulder calcific tendonitis...
  13. doi request reprint Thymic Hassall's corpuscles, regulatory T-cells, and rheumatoid arthritis
    Jean Marie Berthelot
    Rheumatology Unit, Nantes University Hospital, Nantes, France
    Semin Arthritis Rheum 39:347-55. 2010
    ..To review evidence for the involvement of thymic Hassall's corpuscles (HC) in the pathogenesis of rheumatoid arthritis (RA)...
  14. doi request reprint Ultrasonography for diagnosing atypical gout. Two case reports
    Benoit Le Goff
    CHU de Nantes, Service de Rhumatologie, 1 Place Alexis Ricordeau, 44093 Nantes Cedex 1, France
    Joint Bone Spine 75:610-2. 2008
    ..In addition, ultrasonography was useful for guided aspiration of joint fluid or other material containing monosodium urate crystals. Thus, ultrasonography may contribute to improve the diagnosis and treatment of gout...
  15. doi request reprint Three-dimensional versus two-dimensional ultrasonographic assessment of peripheral enthesitis in spondylarthritis
    Oriane Mérot
    Rheumatology Unit, Hotel Dieu, Nantes University Hospital, 1 Place Alexis Ricordeau, 44095, Nantes, France
    Clin Rheumatol 33:131-5. 2014
    ..001). 3D US showed good intra- and interobserver reliability in the assessment of enthesitis in SpA and shortened the needed time for scanning. It can be performed by a nonexperienced examiner without loss of reliability. ..
  16. doi request reprint Pathogenesis of hyperostosis: a key role for mesenchymatous cells?
    Jean Marie Berthelot
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, 44093, Nantes Cedex 01, France Electronic address
    Joint Bone Spine 80:592-6. 2013
    ..These cells normally exert immunosuppressive effects, which may be subverted in spondyloarthritis, notably by a T-cell population that homes specifically to the entheses. ..
  17. doi request reprint Side effects of corticosteroid injections: what's new?
    Jean Marie Berthelot
    Department of Rheumatology, Hotel Dieu, Place Alexis Ricordeau, Nantes University Hospital Center, 44093 Nantes, France
    Joint Bone Spine 80:363-7. 2013
    ..Dexamethasone-based preparations seem to contain no particles or crystals, and have not induced any neurological accidents in various animal models, even after direct administration into vertebral or carotid arteries...
  18. doi request reprint Evidence supporting a role for dormant bacteria in the pathogenesis of spondylarthritis
    Jean Marie Berthelot
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Joint Bone Spine 80:135-40. 2013
    ..TNFα antagonists rarely reactivate dormant bacteria, with the exception of Mycobacterium tuberculosis, which, together with metastatic cells, is the most extensively studied latency model to date...
  19. doi request reprint Regulatory B cells play a key role in immune system balance
    Jean Marie Berthelot
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Joint Bone Spine 80:18-22. 2013
    ..Research into the interactions between the gut microbiota and Bregs holds considerable promise...
  20. doi request reprint Rheumatoid arthritis and periodontal disease
    Jean Marie Berthelot
    Service de Rhumatologie, Hotel Dieu, CHU de Nantes, Place Alexis Ricordeau, 44093 Nantes Cedex 01, France
    Joint Bone Spine 77:537-41. 2010
    ..g., scaling, root planing and, if needed, dental surgery), particularly as periodontitis is also associated with an increased risk of premature atheroma...
  21. doi request reprint High intraindividual week-to-week variability in BASDAI and BASFI values: are several evaluations needed before starting or stopping TNFalpha antagonist therapy for spondyloarthropathies?
    Jean Marie Berthelot
    Hôtel Dieu Teaching Hospital, Nantes, France
    Joint Bone Spine 75:167-71. 2008
    ..To evaluate intraindividual variability of the BASDAI, BASFI, and HAQ in patients with spondyloarthropathies...
  22. doi request reprint OPG, RANK and RANK ligand expression in thyroid lesions
    Marie Françoise Heymann
    INSERM, ERI 7, Nantes, F 44035, France
    Regul Pept 148:46-53. 2008
    ..Thus OPG/RANK/RANKL molecular triad might play a role during pathogenesis of follicular and parafollicular tumors...