Chemical analysis of complex organic mixtures using reactive nanospray desorption electrospray ionization mass spectrometryJulia Laskin
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
Anal Chem 84:7179-87. 2012
..Our results indicate that reactive nano-DESI is a valuable approach for examining the presence of specific functional groups and for the quantification of compounds possessing these groups in complex mixtures...
Tissue imaging using nanospray desorption electrospray ionization mass spectrometryJulia Laskin
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
Anal Chem 84:141-8. 2012
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- Molecular characterization of organic aerosols using nanospray-desorption/electrospray ionization-mass spectrometry
Patrick J Roach
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
Anal Chem 82:7979-86. 2010
..Furthermore, nano-DESI enables the efficient detection of chemically labile compounds in OA, which is important for understanding chemical aging phenomena...
- Molecular characterization of biomass burning aerosols using high-resolution mass spectrometry
Jeffrey S Smith
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
Anal Chem 81:1512-21. 2009
..The increase is particularly pronounced for the samples containing a large number of the CH(2)-based homologous series...
- High-resolution desorption electrospray ionization mass spectrometry for chemical characterization of organic aerosols
Julia Laskin
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
Anal Chem 82:2048-58. 2010
..This study presents an important step toward understanding the formation of light-absorbing OA (brown carbon) in the atmosphere...
- Visualization of high resolution spatial mass spectrometric data during acquisition
Mathew Thomas
Pacific Northwest National Laboratory, Richland, WA 99354, USA
Conf Proc IEEE Eng Med Biol Soc 2012:5545-8. 2012
..This software approach is a significant advance over the previous state-of-the art methods that required the conversion of the RAW data using one software, manual assembly of the data, and visualization in another software...
- Imaging nicotine in rat brain tissue by use of nanospray desorption electrospray ionization mass spectrometry
Ingela Lanekoff
Chemical and Materials Sciences Division and Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States
Anal Chem 85:882-9. 2013
..Such sensitivity is necessary for spatially resolved detection of low-abundance molecules in complex matrices...
Chemical characterization of crude petroleum using nanospray desorption electrospray ionization coupled with high-resolution mass spectrometryPeter A Eckert
William R Wiley Environmental and Molecular Sciences Laboratory, Pacific Northwest National Laboratory, P O Box 999, K8 88, Richland, Washington 99352, USA
Anal Chem 84:1517-25. 2012
..It also enables rapid characterization of water-soluble components of petroleum samples that is difficult to perform using traditional approaches...
- Automated platform for high-resolution tissue imaging using nanospray desorption electrospray ionization mass spectrometry
Ingela Lanekoff
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
Anal Chem 84:8351-6. 2012
..The observed distribution is consistent with the literature data obtained using magnetic resonance spectroscopy...
- Molecular characterization of nitrogen-containing organic compounds in biomass burning aerosols using high-resolution mass spectrometry
Alexander Laskin
William R Wiley Environmental Molecular Sciences Laboratory and Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
Environ Sci Technol 43:3764-71. 2009
..S. areas frequently affected by large scale fires) suggests that N-heterocyclic alkaloids in BBA may play a significant role in dry and wet deposition of fixed nitrogen in this region...
- Nanospray desorption electrospray ionization: an ambient method for liquid-extraction surface sampling in mass spectrometry
Patrick J Roach
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, WA 99352, USA
Analyst 135:2233-6. 2010
..We present analytical capabilities of the method and discuss its potential for imaging applications...
- Higher-order mass defect analysis for mass spectra of complex organic mixtures
Patrick J Roach
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
Anal Chem 83:4924-9. 2011
..Higher-order mass defect analysis is described and demonstrated through third-order analysis of a deisotoped high-resolution mass spectrum of crude oil containing nearly 13,000 peaks...
- Case study of water-soluble metal containing organic constituents of biomass burning aerosol
Alexandra L Chang-Graham
Chemical and Materials Sciences Division, National Security Division, William R Wiley Environmental and Molecular Sciences Laboratory, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, United States
Environ Sci Technol 45:1257-63. 2011
..Further research into the sources, dispersion, and persistence of metal-containing aerosols, as well as their environmental effects, is needed...
- Spatially resolved analysis of glycolipids and metabolites in living Synechococcus sp. PCC 7002 using nanospray desorption electrospray ionization
Ingela Lanekoff
Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, PO Box 999, K8 88 Richland, WA 99352, USA
Analyst 138:1971-8. 2013
..The methodology presented in this study will facilitate future studies focused on molecular-level characterization of interactions between bacterial colonies...
