Julia Laskin

Summary

Publications

  1. doi request reprint Chemical analysis of complex organic mixtures using reactive nanospray desorption electrospray ionization mass spectrometry
    Julia Laskin
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 84:7179-87. 2012
  2. pmc Tissue imaging using nanospray desorption electrospray ionization mass spectrometry
    Julia Laskin
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Anal Chem 84:141-8. 2012
  3. doi request reprint Molecular characterization of organic aerosols using nanospray-desorption/electrospray ionization-mass spectrometry
    Patrick J Roach
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 82:7979-86. 2010
  4. doi request reprint Visualization of high resolution spatial mass spectrometric data during acquisition
    Mathew Thomas
    Pacific Northwest National Laboratory, Richland, WA 99354, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:5545-8. 2012
  5. doi request reprint Molecular characterization of biomass burning aerosols using high-resolution mass spectrometry
    Jeffrey S Smith
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 81:1512-21. 2009
  6. doi request reprint High-resolution desorption electrospray ionization mass spectrometry for chemical characterization of organic aerosols
    Julia Laskin
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 82:2048-58. 2010
  7. pmc High-speed tandem mass spectrometric in situ imaging by nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Physical Sciences Division and Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States
    Anal Chem 85:9596-603. 2013
  8. doi request reprint Imaging nicotine in rat brain tissue by use of nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Anal Chem 85:882-9. 2013
  9. ncbi request reprint Chemical characterization of crude petroleum using nanospray desorption electrospray ionization coupled with high-resolution mass spectrometry
    Peter A Eckert
    William R Wiley Environmental and Molecular Sciences Laboratory, Pacific Northwest National Laboratory, P O Box 999, K8 88, Richland, Washington 99352, USA
    Anal Chem 84:1517-25. 2012
  10. doi request reprint Shotgun approach for quantitative imaging of phospholipids using nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Physical Sciences Division, Pacific Northwest National Laboratory, PO Box 999, K8 88, Richland, Washington 99352, United States
    Anal Chem 86:1872-80. 2014

Collaborators

  • Alexander Laskin
  • Ingela Lanekoff
  • Patrick J Roach
  • Mathew Thomas
  • Peter A Eckert
  • Alexandra L Chang-Graham
  • Jeffrey S Smith
  • Dongsheng Li
  • Ellen Liu
  • Brandi S Heath
  • Andrew P Kuprat
  • James P Carson
  • Katrina Hui
  • Kerstin Kleese van Dam
  • Luisa T M Profeta
  • Robert J Yokelson
  • Timothy J Johnson

Detail Information

Publications16

  1. doi request reprint Chemical analysis of complex organic mixtures using reactive nanospray desorption electrospray ionization mass spectrometry
    Julia Laskin
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 84:7179-87. 2012
    ..Our results indicate that reactive nano-DESI is a valuable approach for examining the presence of specific functional groups and for the quantification of compounds possessing these groups in complex mixtures...
  2. pmc Tissue imaging using nanospray desorption electrospray ionization mass spectrometry
    Julia Laskin
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Anal Chem 84:141-8. 2012
    ....
  3. doi request reprint Molecular characterization of organic aerosols using nanospray-desorption/electrospray ionization-mass spectrometry
    Patrick J Roach
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 82:7979-86. 2010
    ..Furthermore, nano-DESI enables the efficient detection of chemically labile compounds in OA, which is important for understanding chemical aging phenomena...
  4. doi request reprint Visualization of high resolution spatial mass spectrometric data during acquisition
    Mathew Thomas
    Pacific Northwest National Laboratory, Richland, WA 99354, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:5545-8. 2012
    ..This software approach is a significant advance over the previous state-of-the art methods that required the conversion of the RAW data using one software, manual assembly of the data, and visualization in another software...
  5. doi request reprint Molecular characterization of biomass burning aerosols using high-resolution mass spectrometry
    Jeffrey S Smith
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 81:1512-21. 2009
    ..The increase is particularly pronounced for the samples containing a large number of the CH(2)-based homologous series...
  6. doi request reprint High-resolution desorption electrospray ionization mass spectrometry for chemical characterization of organic aerosols
    Julia Laskin
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 82:2048-58. 2010
    ..This study presents an important step toward understanding the formation of light-absorbing OA (brown carbon) in the atmosphere...
  7. pmc High-speed tandem mass spectrometric in situ imaging by nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Physical Sciences Division and Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States
    Anal Chem 85:9596-603. 2013
    ..Furthermore, we identified several metabolites associated with early pregnancy and obtained the first 2D images of these molecules. ..
  8. doi request reprint Imaging nicotine in rat brain tissue by use of nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Anal Chem 85:882-9. 2013
    ..Such sensitivity is necessary for spatially resolved detection of low-abundance molecules in complex matrices...
  9. ncbi request reprint Chemical characterization of crude petroleum using nanospray desorption electrospray ionization coupled with high-resolution mass spectrometry
    Peter A Eckert
    William R Wiley Environmental and Molecular Sciences Laboratory, Pacific Northwest National Laboratory, P O Box 999, K8 88, Richland, Washington 99352, USA
    Anal Chem 84:1517-25. 2012
    ..It also enables rapid characterization of water-soluble components of petroleum samples that is difficult to perform using traditional approaches...
  10. doi request reprint Shotgun approach for quantitative imaging of phospholipids using nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Physical Sciences Division, Pacific Northwest National Laboratory, PO Box 999, K8 88, Richland, Washington 99352, United States
    Anal Chem 86:1872-80. 2014
    ..Furthermore, by combining the quantitative data obtained in the individual pixels, we demonstrate quantification of these PC species in seven different regions of a rat brain tissue section. ..
  11. doi request reprint Automated platform for high-resolution tissue imaging using nanospray desorption electrospray ionization mass spectrometry
    Ingela Lanekoff
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, USA
    Anal Chem 84:8351-6. 2012
    ..The observed distribution is consistent with the literature data obtained using magnetic resonance spectroscopy...
  12. ncbi request reprint Molecular characterization of nitrogen-containing organic compounds in biomass burning aerosols using high-resolution mass spectrometry
    Alexander Laskin
    William R Wiley Environmental Molecular Sciences Laboratory and Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Environ Sci Technol 43:3764-71. 2009
    ..S. areas frequently affected by large scale fires) suggests that N-heterocyclic alkaloids in BBA may play a significant role in dry and wet deposition of fixed nitrogen in this region...
  13. ncbi request reprint Higher-order mass defect analysis for mass spectra of complex organic mixtures
    Patrick J Roach
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, Washington 99352, USA
    Anal Chem 83:4924-9. 2011
    ..Higher-order mass defect analysis is described and demonstrated through third-order analysis of a deisotoped high-resolution mass spectrum of crude oil containing nearly 13,000 peaks...
  14. ncbi request reprint Nanospray desorption electrospray ionization: an ambient method for liquid-extraction surface sampling in mass spectrometry
    Patrick J Roach
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, P O Box 999, MSIN K8 88, Richland, WA 99352, USA
    Analyst 135:2233-6. 2010
    ..We present analytical capabilities of the method and discuss its potential for imaging applications...
  15. doi request reprint Case study of water-soluble metal containing organic constituents of biomass burning aerosol
    Alexandra L Chang-Graham
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA
    Environ Sci Technol 45:1257-63. 2011
    ..Further research into the sources, dispersion, and persistence of metal-containing aerosols, as well as their environmental effects, is needed...
  16. doi request reprint Spatially resolved analysis of glycolipids and metabolites in living Synechococcus sp. PCC 7002 using nanospray desorption electrospray ionization
    Ingela Lanekoff
    Chemical and Materials Sciences Division, Pacific Northwest National Laboratory, PO Box 999, K8 88 Richland, WA 99352, USA
    Analyst 138:1971-8. 2013
    ..The methodology presented in this study will facilitate future studies focused on molecular-level characterization of interactions between bacterial colonies...