James W Larrick

Summary

Publications

  1. doi request reprint Conference scene: progress with promising human antibodies
    James W Larrick
    Panorama Research Institute, Sunnyvale, CA 94089, USA
    Immunotherapy 4:257-61. 2012
  2. pmc Applied Healthspan engineering
    James W Larrick
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 13:265-80. 2010
  3. ncbi request reprint Trade-offs between anti-aging dietary supplementation and exercise
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California
    Rejuvenation Res 16:419-26. 2013
  4. ncbi request reprint Rejuvenation of aging hearts
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 16:330-2. 2013
  5. doi request reprint Ectopic expression of telomerase safely increases health span and life span
    Andrew R Mendelsohn
    Panorama Research Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 15:435-8. 2012
  6. doi request reprint Dietary restriction: critical co-factors to separate health span from life span benefits
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, CA, USA
    Rejuvenation Res 15:523-9. 2012
  7. doi request reprint Fibroblast growth factor-21 is a promising dietary restriction mimetic
    Andrew R Mendelsohn
    Panorama Research Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 15:624-8. 2012
  8. doi request reprint Dietary modification of the microbiome affects risk for cardiovascular disease
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California, USA
    Rejuvenation Res 16:241-4. 2013
  9. ncbi request reprint The DNA methylome as a biomarker for epigenetic instability and human aging
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California, USA
    Rejuvenation Res 16:74-7. 2013
  10. doi request reprint Dissecting mammalian target of rapamycin to promote longevity
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, 1230 Bordeaux Drive, Sunnyvale, California 94089, USA
    Rejuvenation Res 15:334-7. 2012

Collaborators

Detail Information

Publications15

  1. doi request reprint Conference scene: progress with promising human antibodies
    James W Larrick
    Panorama Research Institute, Sunnyvale, CA 94089, USA
    Immunotherapy 4:257-61. 2012
    ..The conference was sponsored by the international journal Human Antibodies, in association with the Integrative Medical Sciences Association (IMSA). The Program Chairman was Professor Mark Glassy, IMSA, San Diego, CA, USA...
  2. pmc Applied Healthspan engineering
    James W Larrick
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 13:265-80. 2010
    ..AHE supports the study of cell, tissue, and organ homeostatic mechanisms to derive new regenerative and tissue replacement therapies to extend the period of human health...
  3. ncbi request reprint Trade-offs between anti-aging dietary supplementation and exercise
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California
    Rejuvenation Res 16:419-26. 2013
    ..Careful attention to individual and family medical history and personal genomic data may prove essential to make wise dietary and supplement choices to be combined with exercise...
  4. ncbi request reprint Rejuvenation of aging hearts
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 16:330-2. 2013
    ..However, much work remains to be done to evaluate the utility of GDF-11 as a therapeutic rejuvenation factor. Similar rejuvenating factors for diverse tissues may exist as well and will hopefully be identified in the near future...
  5. doi request reprint Ectopic expression of telomerase safely increases health span and life span
    Andrew R Mendelsohn
    Panorama Research Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 15:435-8. 2012
    ..Such a positive feedback loop implies that safety must be carefully considered in the development of drugs that stimulate telomerase activity...
  6. doi request reprint Dietary restriction: critical co-factors to separate health span from life span benefits
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, CA, USA
    Rejuvenation Res 15:523-9. 2012
    ..Optimized health span engineering will require a much deeper understanding of DR...
  7. doi request reprint Fibroblast growth factor-21 is a promising dietary restriction mimetic
    Andrew R Mendelsohn
    Panorama Research Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 15:624-8. 2012
    ..More in-depth studies of the effects of FGF21 and its inducers on longevity and health span are warranted...
  8. doi request reprint Dietary modification of the microbiome affects risk for cardiovascular disease
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California, USA
    Rejuvenation Res 16:241-4. 2013
    ..Development of novel therapeutic approaches to manipulate gut flora may help treat CVD...
  9. ncbi request reprint The DNA methylome as a biomarker for epigenetic instability and human aging
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California, USA
    Rejuvenation Res 16:74-7. 2013
    ..The model may eventually lead to experiments to differentiate the contributions of biomolecular damage and noise/incomplete structural replication during aging...
  10. doi request reprint Dissecting mammalian target of rapamycin to promote longevity
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, 1230 Bordeaux Drive, Sunnyvale, California 94089, USA
    Rejuvenation Res 15:334-7. 2012
    ..The search for inhibitors of the mTORC1 component Raptor may prove a productive approach to create a better mTOR inhibitor...
  11. ncbi request reprint Partial Reversal of Skeletal Muscle Aging by Restoration of Normal NAD(+) Levels
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California
    Rejuvenation Res 17:62-9. 2014
    ..Work to elucidate other biphasic aging mechanisms is strongly encouraged. ..
  12. ncbi request reprint Paradoxical effects of antioxidants on cancer
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California
    Rejuvenation Res 17:306-11. 2014
    ..Personal genomic analysis may provide the means to identify context to avoid these paradoxes and obtain a successful outcome. However, cancer prevention may be more difficult than previously thought. ..
  13. doi request reprint Sleep facilitates clearance of metabolites from the brain: glymphatic function in aging and neurodegenerative diseases
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California
    Rejuvenation Res 16:518-23. 2013
    ..A public health initiative to ensure adequate sleep among middle-aged and older people may prove useful in preventing AD, especially in apolipoprotein E (ApoE) ɛ4 carriers...
  14. doi request reprint Rejuvenation of adult stem cells: is age-associated dysfunction epigenetic?
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, California 94089, USA
    Rejuvenation Res 16:152-7. 2013
    ..If true, rejuvenation of at least some aged cells may be simpler than generally appreciated...
  15. doi request reprint Epigenetic-mediated decline in synaptic plasticity during aging
    Andrew R Mendelsohn
    Panorama Research Institute and Regenerative Sciences Institute, Sunnyvale, CA 94089, USA
    Rejuvenation Res 15:98-101. 2012
    ..Such dysfunctional epigenetic pathways may provide novel targets for cognitive enhancing therapeutics...