[Epidemiology of stroke in Guadeloupe and role of sickle cell trait]A Lannuzel
Service de Neurologie, Centre Hospitalier Universitaire de Pointe à Pitre, Faculté Antilles Guyane, Guadeloupe
Rev Neurol (Paris) 155:351-6. 1999
..The influence of AS heterozygote on the occurrence of stroke needs to be examined in a longitudinal, prospective study...
Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in GuadeloupeAnnie Lannuzel
Service de Neurologie, Centre Hospitalier Universitaire des Antilles et de la Guyane, Pointe a Pitre, Guadeloupe, France
Mov Disord 17:84-90. 2002
..It is therefore conceivable that repeated consumption could cause the neuronal dysfunction and degeneration underlying the West Indian parkinsonian syndrome...
Risk factors associated with ischaemic stroke in GuadeloupeJ Bangou-Bredent
Laboratoire de Biochimie, Service de Neurologie, Dept d Information Médicale et Santé Publique, CHU de la Guadeloupe, FWI et INSERM U330, Universite de Bordeaux 2, France
West Indian Med J 49:302-6. 2000
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The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolismA Lannuzel
Department of Neurology, CHU Antilles Guyane, BP 465, 97159 Pointe a Pitre, Guadeloupe, France
Neuroscience 121:287-96. 2003
..It also underlines the need to address its possible role in the etiology of some atypical forms of Parkinsonism in Guadeloupe...
Atypical parkinsonism in Guadeloupe: a common risk factor for two closely related phenotypes?Annie Lannuzel
Department of Neurology, Hospital of Pointe a Pitre, Guadeloupe, F W I
Brain 130:816-27. 2007
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Experimental evidence for a toxic etiology of tropical parkinsonismGünter U Höglinger
Mov Disord 20:118-9. 2005
Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in GuadeloupePierre Champy
Experimental Neurology and Therapeutics, INSERM U289, , Paris, France
J Neurochem 88:63-9. 2004
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Guadeloupean parkinsonism: a cluster of progressive supranuclear palsy-like tauopathyDominique Caparros-Lefebvre
Neurologie, Centre Hospitalier Universitaire de la Guadeloupe, Pointe a Pitre, French West Indies
Brain 125:801-11. 2002
..A cluster of cases presenting with atypical parkinsonism is reported. Guadeloupean parkinsonism may prove to be a tauopathy identical or closely related to PSP...
REM sleep behavior disorder in patients with guadeloupean parkinsonism, a tauopathyValerie Cochen De Cock
Service de Neurologie, Hopital Saint Antoine, Paris, France
Sleep 30:1026-32. 2007
..It is possibly caused by the ingestion of sour sop (corossol), a tropical fruit containing acetogenins, which are mitochondrial poisons...
Neurological manifestations of Behçet's disease in a Caribbean population: clinical and imaging findingsAnnie Lannuzel
Department of Neurology, Centre Hospitalier Universitaire des Antilles et de la Guyane, 97159, Pointe A Pitre cedex, Guadeloupe, French West Indies, France
J Neurol 249:410-8. 2002
..This study suggests that the frequency of BD in this Afro-Caribbean population is higher than this reported in Caucasian populations. Meningoencephalitis is associated with a poor prognosis while other patients achieved recovery...
Quantification of acetogenins in Annona muricata linked to atypical parkinsonism in guadeloupePierre Champy
Laboratory of Pharmacognosy, UMR 8076 Centre National de la Recherche Scientifique BioCIS, , , France
Mov Disord 20:1629-33. 2005
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The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathyGünter U Höglinger
INSERM U679, Hopital de la Salpetriere, Paris, France
J Neurochem 95:930-9. 2005
..Our data suggest that chronic respiratory chain dysfunction might trigger a form of neurodegeneration in which accumulation of hyperphosphorylated tau protein predominates over deposits of alpha-synuclein...
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neuronsMyriam Escobar Khondiker
Experimental Neurology, Philipps University, D 35033 Marburg, Germany
J Neurosci 27:7827-37. 2007
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