Philipp A Lang
Lang P, Cervantes Barragan L, Verschoor A, Navarini A, Recher M, Pellegrini M, et al
. Hematopoietic cell-derived interferon controls viral replication and virus-induced disease. Blood. 2009;113:1045-52 pubmed publisher
..These data suggest that during systemic viral infection primarily hematopoietic cell-derived IFN-I controls viral replication and viral-induced disease. ..
Lang P, Recher M, Honke N, Scheu S, Borkens S, Gailus N, et al
. Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice. Hepatology. 2010;52:25-32 pubmed publisher
..In the absence of Kupffer cells, hepatocytes were not able to suppress virus replication, even in the presence of IFN-I, leading to prolonged viral replication and severe T cell-dependent immunopathology...