Irene V Lambrinoudaki

Summary

Publications

  1. ncbi Mammographic changes associated with raloxifene and tibolone therapy in postmenopausal women: a prospective study
    George E Christodoulakos
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Greece
    Menopause 9:110-6. 2002
  2. ncbi Determinants of serum leptin levels in healthy postmenopausal women
    I Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    J Endocrinol Invest 26:1225-30. 2003
  3. ncbi Breast pain and mammographic density increase as a consequence of raloxifene therapy
    G E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Greece
    J Endocrinol Invest 25:564-6. 2002
  4. ncbi The effect of various regimens of hormone replacement therapy on mammographic breast density
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, Aretaieion Hospital, University of Athens, 3, Neofytou Douka Street, GR 10674, Athens, Greece
    Maturitas 45:109-18. 2003
  5. ncbi Effect of hormone replacement therapy and tibolone on serum leptin levels in postmenopausal women
    Irene V Lambrinoudaki
    Second Department of Obstetrics and Gynecology, Aretaieion Hospital, University of Athens, 3 Neofytou Douka Street, GR-10674, Greece
    Maturitas 48:107-13. 2004
  6. ncbi Genetics in gestational diabetes mellitus: association with incidence, severity, pregnancy outcome and response to treatment
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, Aretaieion University Hospital, Athens University Medical School, GR 11528, Athens, Greece
    Curr Diabetes Rev 6:393-9. 2010
  7. ncbi Endogenous sex hormones and risk factors for atherosclerosis in healthy Greek postmenopausal women
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Greece
    Eur J Endocrinol 154:907-16. 2006
  8. ncbi Bisphosphonates
    Irene Lambrinoudaki
    Second Department of Obstetrics and Gynecology, University of Athens, Artetaieio Hospital, Athens, Greece
    Ann N Y Acad Sci 1092:397-402. 2006
  9. ncbi Circulating leptin and ghrelin are differentially influenced by estrogen/progestin therapy and raloxifene
    Irene V Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, 27 Themistokleous Street, Dionysos, Athens, Greece
    Maturitas 59:62-71. 2008
  10. ncbi Measurable serum markers of oxidative stress response in women with endometriosis
    Irene V Lambrinoudaki
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, Athens, Greece
    Fertil Steril 91:46-50. 2009

Collaborators

  • Demetrios Rizos
  • Theodoros N Sergentanis
  • Areti Augoulea
  • George P Lyritis
  • Nicholas Tentolouris
  • I A Dontas
  • E Deligeoroglou
  • George E Christodoulakos
  • George C Creatsas
  • G Christodoulakos
  • G Creatsas
  • C Panoulis
  • Constantinos P Panoulis
  • Emmanuel V Economou
  • Evangelia E Kouskouni
  • Spyros G Dendrinos
  • Athina D Vourtsi
  • Konstantinos P C Panoulis
  • Maria Karaflou
  • Constantinos Papadias
  • Sofia A Vlachou
  • Kalliopi L Koundi
  • Dimitrios S Botsis
  • Makarios I Eleftheriades
  • Constantinos P C Panoulis
  • G E Christodoulakos
  • A Vourtsi
  • G Kaparos
  • L Aravantinos
  • George Christodoulakos
  • Nikolaos Vitoratos
  • Maria G Creatsa
  • Ioannis M Zervas
  • Andreas P Alexandrou
  • Pavlos N Sakkas
  • Sofia Vlachou
  • Maria Creatsa
  • Constantinos R Soldatos
  • Panagiota Fexi
  • Vasiliki D Papagianni
  • Apostolos V Kountouris
  • Areti Spyropoulou
  • Dimitrios Botsis
  • Andreas Alexandrou
  • Despoina N Perrea
  • G Caramalis
  • V Sioulas
  • Odysseas V Gregoriou
  • Panagiota D Raptou
  • Aristidis G Antoniou
  • D Botsis
  • A Sarandakou
  • C Papadias
  • A Alexandrou
  • Emanuel Economou
  • T Liakakos
  • L Vlachos
  • E Georgiou
  • K P Panoulis
  • A D Vourtsi
  • Dimitrios A Kelekis
  • G C Creatsas

Detail Information

Publications31

  1. ncbi Mammographic changes associated with raloxifene and tibolone therapy in postmenopausal women: a prospective study
    George E Christodoulakos
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Greece
    Menopause 9:110-6. 2002
    ..The aim of this study was to evaluate the effect of two alternative to estrogens drugs, the selective estrogen receptor modulator raloxifene and the tissue-specific tibolone, on the mammographic appearance of the breast...
  2. ncbi Determinants of serum leptin levels in healthy postmenopausal women
    I Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    J Endocrinol Invest 26:1225-30. 2003
    ..Neither endogenous estradiol, nor endogenous testosterone are associated with leptin levels. Further studies are needed to elucidate the role of leptin in determining body weight and composition in postmenopausal women...
  3. ncbi Breast pain and mammographic density increase as a consequence of raloxifene therapy
    G E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Greece
    J Endocrinol Invest 25:564-6. 2002
    ..Therapy was accordingly stopped and mastodynia subsided. The patient's mammogram regressed to pre-treatment status after 6 months off-therapy...
  4. ncbi The effect of various regimens of hormone replacement therapy on mammographic breast density
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, Aretaieion Hospital, University of Athens, 3, Neofytou Douka Street, GR 10674, Athens, Greece
    Maturitas 45:109-18. 2003
    ..To evaluate the effect of three distinct hormone replacement therapy regimens on mammography...
  5. ncbi Effect of hormone replacement therapy and tibolone on serum leptin levels in postmenopausal women
    Irene V Lambrinoudaki
    Second Department of Obstetrics and Gynecology, Aretaieion Hospital, University of Athens, 3 Neofytou Douka Street, GR-10674, Greece
    Maturitas 48:107-13. 2004
    ..Further studies are required to verify the exact role of estrogen and tibolone on leptin production and function in postmenopausal women...
  6. ncbi Genetics in gestational diabetes mellitus: association with incidence, severity, pregnancy outcome and response to treatment
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, Aretaieion University Hospital, Athens University Medical School, GR 11528, Athens, Greece
    Curr Diabetes Rev 6:393-9. 2010
    ..This review focuses on possible gestational diabetes mellitus susceptibility genes and their association with the disease incidence and severity as well as the pregnancy outcome and the response to treatment...
  7. ncbi Endogenous sex hormones and risk factors for atherosclerosis in healthy Greek postmenopausal women
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Greece
    Eur J Endocrinol 154:907-16. 2006
    ..To assess the association between endogenous sex hormones and risk factors for atherosclerosis in healthy postmenopausal women...
  8. ncbi Bisphosphonates
    Irene Lambrinoudaki
    Second Department of Obstetrics and Gynecology, University of Athens, Artetaieio Hospital, Athens, Greece
    Ann N Y Acad Sci 1092:397-402. 2006
    ..v.) infusion once annually...
  9. ncbi Circulating leptin and ghrelin are differentially influenced by estrogen/progestin therapy and raloxifene
    Irene V Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, 27 Themistokleous Street, Dionysos, Athens, Greece
    Maturitas 59:62-71. 2008
    ..Apoptosis may be one pathway through which the actions of these hormones are mediated. Sex hormones are reported to influence the secretion and action of ghrelin and leptin...
  10. ncbi Measurable serum markers of oxidative stress response in women with endometriosis
    Irene V Lambrinoudaki
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, Athens, Greece
    Fertil Steril 91:46-50. 2009
    ..To evaluate the hypothesis of increased systemic oxidative stress in patients with endometriosis...
  11. ncbi CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women
    Irene V Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, Athens, Greece
    Menopause 15:1163-8. 2008
    ....
  12. ncbi Apoptosis in atherosclerosis: a mini-review
    Maria Karaflou
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, 27 Themistokleous Street, Dionysos, Athens, Greece
    Mini Rev Med Chem 8:912-8. 2008
    ..However, once the plaque is formed, apoptosis may lead to plaque rupture and thrombosis...
  13. ncbi Methylenetetrahydrofolate reductase C677T polymorphism is associated with central adiposity and increased androgenicity in healthy postmenopausal women
    Irene Lambrinoudaki
    Second Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, 27, Themistokleous Street, Dionysos, GR 14578 Athens, Greece
    Eur J Endocrinol 159:233-41. 2008
    ..To assess the association of genetic polymorphisms related to cardiovascular disease (CVD) risk with anthropometric parameters and indices of androgenicity in healthy postmenopausal women...
  14. ncbi Once-yearly zoledronic acid in the prevention of osteoporotic bone fractures in postmenopausal women
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Greece
    Clin Interv Aging 3:445-51. 2008
    ..Rare adverse effects include renal dysfunction, hypocalcemia, atrial fibrillation, and osteonecrosis of the jaw...
  15. ncbi Apolipoprotein E and paraoxonase 1 polymorphisms are associated with lower serum thyroid hormones in postmenopausal women
    Irene Lambrinoudaki
    Second Department of Obstetrics and Gynaecology, University of Athens, Aretaieio Hospital, Athens, Greece
    Clin Endocrinol (Oxf) 71:284-90. 2009
    ..Autoimmune thyroiditis and overt or subclinical hypothyroidism have been associated with increased prevalence of cardiovascular disease (CVD)...
  16. ncbi Thyroid function and postpartum mood disturbances in Greek women
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, 27, Themistokleous Street, Dionysos GR 14578, Athens, Greece
    J Affect Disord 121:278-82. 2010
    ..5% among Greek women. This study aimed to investigate whether thyroid function within the normal range affects the incidence of postpartum mood disturbances...
  17. ncbi Endogenous sex steroids and bone mineral density in healthy Greek postmenopausal women
    Irene Lambrinoudaki
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    J Bone Miner Metab 24:65-71. 2006
    ..Thus, endogenous steroids are significant determinants of postmenopausal BMD. Endogenous estradiol may be more important for lumbar spine BMD, whereas endogenous androgens are associated mainly with femoral neck BMD...
  18. ncbi Effect of hormone replacement therapy and tibolone on serum total homocysteine levels in postmenopausal women
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, 3 Neofytou Douka Street, Athens GR 10674, Greece
    Eur J Obstet Gynecol Reprod Biol 112:74-9. 2004
    ..To assess the effect of continuous combined hormone replacement therapy (HRT) or tibolone on serum total homocysteine (tHcy) levels in postmenopausal women...
  19. ncbi The effect of hormone therapy and raloxifene on serum matrix metalloproteinase-2 and -9 in postmenopausal women
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    Menopause 11:299-305. 2004
    ..The aim of the study was to investigate the effect of continuous-combined hormone therapy and raloxifene on the total and active forms of serum matrix metalloproteinase (MMP) -2 and -9...
  20. ncbi Endogenous sex steroids and circulating homocysteine in healthy Greek postmenopausal women
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens University Medical School
    Hormones (Athens) 5:35-41. 2006
    ..CONCLUSIONS: Endogenous estrogens and not androgens are related to serum homocysteine values in postmenopausal women. Whether this association has clinical implications remains to be clarified...
  21. ncbi Circulating chemoattractants RANTES, negatively related to endogenous androgens, and MCP-1 are differentially suppressed by hormone therapy and raloxifene
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, Athens, Greece
    Atherosclerosis 193:142-50. 2007
    ..Furthermore, the conflicting reports on the cardiovascular effects of hormone therapy between observational and clinical trials have triggered interest on the effect of alternative therapies on the cardiovascular system...
  22. ncbi The effect of low dose hormone therapy on mammographic breast density
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, 27, Themistokleous Street, Dionysos, GR-14578 Athens, Greece
    Maturitas 54:78-85. 2006
    ..CONCLUSIONS: Different hormone therapy regimens have a variable impact on breast density probably depending on the steroid used. Low dose hormone therapy associates with significantly lesser increase in breast density...
  23. ncbi A 5-year study on the effect of hormone therapy, tibolone and raloxifene on vaginal bleeding and endometrial thickness
    George E Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, 27 Themistokleous Street, GR-14578 Dionysos, Athens, Greece
    Maturitas 53:413-23. 2006
    ..Tibolone expressed a favorable endometrial profile, as seen in its effect on unscheduled spotting/bleeding and mean endometrial thickness. Raloxifene associated with the lowest incidence in S/B and the lowest drop-out rate.s...
  24. ncbi Differential effect of hormone therapy and tibolone on lipids, lipoproteins, and the atherogenic index of plasma
    George E Christodoulakos
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieio Hospital, Athens, Greece
    J Cardiovasc Pharmacol 47:542-8. 2006
    ..In fact, the concurrent assessment of the therapy effect on both LDL-C and AIP may be more dependable in evaluating the cardiovascular impact of a given regimen...
  25. ncbi Quality of life and psychological symptoms in Greek postmenopausal women: association with hormone therapy
    Kalliopi L Koundi
    Athens University Medical School, Women's Mental Health Clinic, Department of Psychiatry, Eginition Hospital, Athens, Greece
    Gynecol Endocrinol 22:660-8. 2006
    ....
  26. ncbi Effect of oral contraceptive treatment on bone mass acquisition in skeletally immature young female rats
    Makarios I Eleftheriades
    Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, GR-11528 Athens, Greece
    Contraception 71:362-71. 2005
    ..046). Our results suggest that OC administration to skeletally immature female rats allows normal bone accrual and may even improve bone geometry. This effect may be mediated through enhanced inhibition of bone resorption...
  27. ncbi Serum androgen levels and insulin resistance in postmenopausal women: association with hormone therapy, tibolone and raloxifene
    G Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, V. Sofias 76, GR-11528, Athens, Greece
    Maturitas 50:321-30. 2005
    ..CONCLUSIONS: CEE/MPA users had lower free testosterone and improved insulin sensitivity. Tibolone on the other hand associated with higher free testosterone, while raloxifene did not relate to any of these parameters...
  28. ncbi Progestin may modify the effect of low-dose hormone therapy on mammographic breast density
    C Panoulis
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    Climacteric 12:240-7. 2009
    ..To evaluate the effect on breast density of two low-dose hormone therapy regimens identical in their estrogen component but different in the progestin...
  29. ncbi Effect of hormone therapy on the elastic properties of the arteries in healthy postmenopausal women
    N Tentolouris
    Department of Propedeutic Medicine, Laiko Hospital, Athens, Greece
    J Endocrinol Invest 28:305-11. 2005
    ..1 +/- 8.9 vs 34.9 +/- 9.8, p=0.72, respectively). The results of this preliminary report suggest that HT for 1 yr does not have any significant effect on central aortic pressure and wave reflection in healthy postmenopausal women...
  30. ncbi Cardiovascular disease: screening and management of the a-symptomatic high-risk post-menopausal woman
    G Creatsas
    2nd Department of Obstetrics and Gynaecology, University of Athens, School of Medicine, 27, Themistokleous Street, Dionysos, GR-14578 Athens, Greece
    Maturitas 52:S32-7. 2005
    ..Non-pharmacological intervention should be targeted towards smoking cessation, a low-salt, low-fat, high-fibre diet and increased physical activity...
  31. ncbi Effect of hormone therapy, tibolone and raloxifene on circulating vascular endothelial growth factor in Greek postmenopausal women
    G Christodoulakos
    2nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece
    Eur J Endocrinol 151:187-92. 2004
    ..Further research is needed to clarify the clinical relevance of these findings with respect to cardiovascular risk in postmenopausal women...