Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidiaClaude Lamarre
Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
BMC Genomics 9:417. 2008
..fumigatus genome)...
Testing the efficacy of RNA interference constructs in Aspergillus fumigatusChristine Henry
Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724, Paris Cedex 15, France
Curr Genet 51:277-84. 2007
..These disadvantages of RNAi indicate that classical gene disruption by gene replacement remains the most efficient method for a molecular analysis of gene function in A. fumigatus...
- A novel family of dehydrin-like proteins is involved in stress response in the human fungal pathogen Aspergillus fumigatus
Joanne Wong Sak Hoi
Unite des Aspergillus, Institut Pasteur, 75015 Paris, France
Mol Biol Cell 22:1896-906. 2011
..Accordingly, DprA and DprB were important for peroxisome function. Our findings reveal a novel family of stress-protective proteins in A. fumigatus and, potentially, in filamentous ascomycetes...
Functional analysis of the superoxide dismutase family in Aspergillus fumigatusKarine Lambou
Unite des Aspergillus, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France
Mol Microbiol 75:910-23. 2010
..In spite of these phenotypes, no significant virulence difference was observed between the triple mutant and parental strain in experimental murine aspergillosis models in immunocompromised animals...
- Galactofuranose attenuates cellular adhesion of Aspergillus fumigatus
Claude Lamarre
Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
Cell Microbiol 11:1612-23. 2009
..Removal of the mannan layer from the mutant surface by a mannosidase treatment abolishes mycelial adhesion to surfaces...
- Characterization of glucuronic acid containing glycolipid in Aspergillus fumigatus mycelium
Thierry Fontaine
Institut Pasteur, Paris, France
Carbohydr Res 344:1960-7. 2009
..Gene deletion showed that only UGD1 is essential for the biosynthesis of GlcA-DG. However, no particular phenotype has been observed in the Ugd1Delta mutant. Biological function of this acidic glycolipid remains unknown in A. fumigatus...
- An extracellular matrix glues together the aerial-grown hyphae of Aspergillus fumigatus
Anne Beauvais
Aspergillus Unit, Institut Pasteur, Paris, France
Cell Microbiol 9:1588-600. 2007
..This is the first analysis of the three dimensional structure of a mycelial colony. Knowledge of this multicellular organization will impact our future understanding of the pathobiology of aerial mold pathogens...
- Deletion of GEL2 encoding for a beta(1-3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus
Isabelle Mouyna
Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
Mol Microbiol 56:1675-88. 2005
..These data suggest for the first time that beta(1-3)glucanosyltransferase activity is required for both morphogenesis and virulence in A. fumigatus...
- Characterization of the SKN7 ortholog of Aspergillus fumigatus
Claude Lamarre
Unite des Aspergillus, Institut Pasteur, 25 rue du Docteur Roux, 75724 Cedex 15, France
Fungal Genet Biol 44:682-90. 2007
..This result indicated that an increased sensitivity of A. fumigatus to peroxides in vitro is not correlated with a modification of fungal virulence...
- Gene silencing with RNA interference in the human pathogenic fungus Aspergillus fumigatus
Isabelle Mouyna
Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
FEMS Microbiol Lett 237:317-24. 2004
..Use of RNA interference in Aspergillus will allow easier examination of the phenotypic consequences of reducing expression of a gene of interest, especially for essential genes...
