Juan Lama

Summary

Publications

  1. ncbi Host factors influencing susceptibility to HIV infection and AIDS progression
    Juan Lama
    La Jolla Institute for Molecular Medicine, 4570 Executive Drive, Suite 100, San Diego, California 92121, USA
    Retrovirology 4:52. 2007
  2. ncbi The physiological relevance of CD4 receptor down-modulation during HIV infection
    Juan Lama
    Department of Medicine and UCSD Cancer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0665, USA
    Curr HIV Res 1:167-84. 2003
  3. ncbi Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication
    Enrique R Argañaraz
    Department of Medicine, School of Medicine, University of California, La Jolla, 92093, USA
    J Biol Chem 278:33912-9. 2003

Collaborators

  • F Kirchhoff
  • Enrique R Argañaraz
  • María J Cortes
  • Michael Schindler

Detail Information

Publications3

  1. ncbi Host factors influencing susceptibility to HIV infection and AIDS progression
    Juan Lama
    La Jolla Institute for Molecular Medicine, 4570 Executive Drive, Suite 100, San Diego, California 92121, USA
    Retrovirology 4:52. 2007
    ..In this review we summarize the available literature on the roles of cellular factors and their genetic variation in modulating HIV infection and disease progression...
  2. ncbi The physiological relevance of CD4 receptor down-modulation during HIV infection
    Juan Lama
    Department of Medicine and UCSD Cancer Center, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0665, USA
    Curr HIV Res 1:167-84. 2003
    ..Addressing the reasons why this function is so critical and understanding the interplay between viral and host factors governing surface expression of CD4 may provide clues for the development of new antiviral strategies...
  3. ncbi Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication
    Enrique R Argañaraz
    Department of Medicine, School of Medicine, University of California, La Jolla, 92093, USA
    J Biol Chem 278:33912-9. 2003
    ..These strains efficiently overcome the deleterious effects of CD4 and replicate more aggressively in CD4-positive primary lymphocytes. These results highlight the importance of the virus-induced CD4 down-modulation in HIV-1 pathogenesis...