Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in TaiwanTe Jen Lai
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, Republic of China
BMC Med Genet 6:14. 2005
..This study was designed to investigate sequence variants of the TPH1 gene in Taiwanese and to test whether the TPH1 gene is a susceptibility factor for the BPD...
Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han ChineseYi Mei J Lin
Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan
Behav Brain Funct 4:21. 2008
..abstract:..
- A 64-week, multicenter, open-label study of aripiprazole effectiveness in the management of patients with schizophrenia or schizoaffective disorder in a general psychiatric outpatient setting
Ming Hong Hsieh
Department of Psychiatry, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan
Ann Gen Psychiatry 9:35. 2010
..To evaluate the overall long-term effectiveness of aripiprazole in patients with schizophrenia in a general psychiatric practice setting in Taiwan...
Overcoming the difficulties in laparoscopic management of contracted gallbladders with gallstones: possible role of fundus-down approachShing Moo Huang
Institute and School of Medicine, Chung Shan Medical University, Taichung, Taiwan, Republic of China
Surg Endosc 25:284-91. 2011
..The aim of this study is to compare efficacy and complications between fundus-down and conventional laparoscopic cholecystectomy (LC) in treating contracted gallbladders with gallstones...
- Social support and mobility limitation as modifiable predictors of improvement in depressive symptoms in the elderly: results of a national longitudinal study
Chun Te Lee
Institute of Medicine, Chung Shan Medical University, No 110, Sec 1, Jianguo N Rd, Taichung 402, Taiwan
Arch Gerontol Geriatr 55:530-8. 2012
....
- Leisure activity, mobility limitation and stress as modifiable risk factors for depressive symptoms in the elderly: results of a national longitudinal study
Chun Te Lee
Institute of Medicine, Chung Shan Medical University, No 110, Sec 1, Jianguo N Rd, Taichung, 402, Taiwan
Arch Gerontol Geriatr 54:e221-9. 2012
..These results indicated that interventions to prevent or reduce depression in older adults should include practical strategies aimed at these modifiable risk factors...
- Blockade of metabotropic glutamate receptors inhibits cognition and neurodegeneration in an MPTP-induced Parkinson's disease rat model
Ming Hong Hsieh
Institute of Medicine, Chung Shan Medical University, Taiwan, ROC
Pharmacol Biochem Behav 102:64-71. 2012
..These data provide support for a role of mGluR5s in the pathophysiology of PD and suggest that MPEP is a promising pharmacological tool for the development of new treatments for dementia associated with PD...
- Pathophysiological significance of gallbladder volume changes in gallstone diseases
Shing Moo Huang
Department and Institute of Biomedical Science, Chung Shan Medical University, No 110, Sec 1, Jianguo N Rd, Taichung 40201, Taiwan, China
World J Gastroenterol 16:4341-7. 2010
..To study the pathophysiological significance of gallbladder volume (GBV) and ejection fraction changes in gallstone patients...
- Change in depressive status and mortality in elderly persons: Results of a national longitudinal study
Po Ren Teng
Institute of Medicine, Chung Shan Medical University, Taiwan Department of Psychiatry, Chang Bing Show Chwan Memorial Hospital, Taiwan
Arch Gerontol Geriatr 56:244-9. 2013
..The link between changing depressive status, gender, ethnicity and mortality warrants further investigation...
- Determinants of cognitive impairment over time among the elderly in Taiwan: results of the national longitudinal study
Chi Hua Yen
Institute of Medicine, Chung Shan Medical University, No 110 sec 1, Chien Kuo N Rd, Taichung 402, Taiwan
Arch Gerontol Geriatr 50:S53-7. 2010
..06, 95% CI = 1.38-3.09), and having a history of diabetes (OR = 1.70, 95% CI = 1.06-2.74) or stroke (OR = 2.36, 95% CI = 1.06-5.26) were independent predictors for cognitive impairment in Taiwan...
- Medical costs and vasculometabolic comorbidities among patients with bipolar disorder in Taiwan - A population-based and matched-control study
Ming Hong Hsieh
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan Department of Psychiatry, Chung Shan Medical University Hospital, Taichung, Taiwan
J Affect Disord 141:449-56. 2012
..The aims of this study were to explore the 1-year treatment cost, including total medical and non-psychiatric services, and the prevalence of vasculometabolic comorbidities in individuals with BD...
- Effects of MK-801 on recognition and neurodegeneration in an MPTP-induced Parkinson's rat model
Ming Hong Hsieh
Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan, ROC
Behav Brain Res 229:41-7. 2012
..These results suggest that NMDA receptors are involved in PD-related neuronal and behavioral dysfunction...
An association between BPDE-like DNA adduct levels and P53 gene mutation in pterygiumTe Jen Lai
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Mol Vis 12:1687-91. 2006
..Therefore, BPDE-like DNA adduct, p53 protein expression and p53 gene mutation were examined in this study to provide more molecular evidence to understand the cause of p53 gene mutation in pterygium...
- Modification effects of coping on post-traumatic morbidity among earthquake rescuers
Chia Ming Chang
Department of Psychiatry and Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Psychiatry Res 158:164-71. 2008
..However, coping strategies do not seem to reduce the influence of such exposure on trauma-related morbidities. This suggests that coping strategies can be used to prevent general psychiatric morbidity but not trauma-related morbidities...
- Laparoscopic primary closure of common bile duct combined with percutaneous cholangiographic drainage for treating choledocholithiasis
Shing Moo Huang
Institute of Medicine, Chung Shan Medical University, Taiwan, Republic of China
Am Surg 76:517-21. 2010
..It seems that laparoscopic primary closure of the CBD combined with PTCD can shorten the operation time and postoperative stays as compared with laparoscopic choledocholithotomy with T-tube placement for the treatment of CBD stones...
- Severity of heroin dependence in Taiwan: reliability and validity of the Chinese version of the Severity of Dependence Scale (SDS[Ch])
Vincent Chin Hung Chen
Department of Psychiatry, Chung Shan Medical University Hospital, 1142, Sec 3, Tai Yuan Rd, Taichung, Taiwan
Addict Behav 33:1590-3. 2008
..The findings support the suggestion that the concept of dependence as assessed by the SDS has cross-cultural validity...
- Full and partial PTSD among earthquake survivors in rural Taiwan
Te-Jen Lai
Institute of Medicine, Chung Shan Medical University and Department of Psychiatry, Chung Shan Medical Hospital, Taichung, Taiwan
J Psychiatr Res 38:313-22. 2004
..In conclusion, PTSD and PTSS are commonly observed following earthquake exposure and are associated with similarly high levels of psychosocial impairment...
- Posttraumatic distress and coping strategies among rescue workers after an earthquake
Chia-Ming Chang
Department of Psychiatry and Graduate Institute of Medicine, Chung Shan Medical University, No. 110, Sec 1, Chien Kuo N. Road, Taichung, Taiwan
J Nerv Ment Dis 191:391-8. 2003
..Rescue workers with longer job experience were at the highest risk for developing psychiatric and posttraumatic distress...
- Predictors of posttraumatic outcomes following the 1999 Taiwan earthquake
Chia-Ming Chang
Department of Psychiatry and Institute of Medicine, Chung Shan Medical University, Chien Kuo N. Road, Taichung 402, Taiwan
J Nerv Ment Dis 193:40-6. 2005
..These variables, particularly female gender, current depression, and impaired well-being, should be considered in assessing earthquake survivors who are at increased risk for developing posttraumatic sequelae...
- A cohort study of behavioral problems and intelligence in children with high prenatal polychlorinated biphenyl exposure
Te-Jen Lai
Department of Psychiatry, Chung Shan Medical University, Taichung, Taiwan
Arch Gen Psychiatry 59:1061-6. 2002
..CONCLUSIONS: Prenatal exposure to these compounds produces long-lasting cognitive and behavioral damage, but there is some evidence of recovery...
- Sequence variants and haplotype analysis of serotonin transporter gene and association with bipolar affective disorder in Taiwan
H Sunny Sun
Institute of Molecular Medicine, National Cheng Kung University Medical College, Tainan, Taiwan
Pharmacogenetics 14:173-9. 2004
..This study examined the role of SLC6A4 in etiology of BPD in a Taiwanese population...
- Association of functional polymorphisms of the human tryptophan hydroxylase 2 gene with risk for bipolar disorder in Han Chinese
Yi Mei J Lin
Institute of Basic Medical Sciences, National Cheng Kung University Medical College, Tainan 70101, Taiwan
Arch Gen Psychiatry 64:1015-24. 2007
....
- The endocrine and reproductive function of the female Yucheng adolescents prenatally exposed to PCBs/PCDFs
Chiu-Yueh Yang
Department of Environmental and Occupational Health, National Cheng Kung University Medical College, 61 Shiao Tong Road, Tainan, 70428, Taiwan
Chemosphere 61:355-60. 2005
..CONCLUSIONS: We conclude that prenatal exposure to PCBs/PCDFs resulted in abnormal menstruation and higher estradiol and FSH levels in follicular phase of menstrual cycle in adolescent girls...
- Employment experience in relation to alcohol, tobacco, and betel nut use among youth in Taiwan
Chuan-Yu Chen
Division of Mental Health and Substance Abuse Research, National Health Research Institutes, Taipei, Taiwan
Drug Alcohol Depend 84:273-80. 2006
..Future prevention programs may target this high-risk group to reduce possible drug-related negative consequences in developmental and health domains in Taiwan...
- Symptoms of neurasthenia following earthquake trauma: re-examination of a discarded syndrome
Wei Zhang
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
Psychiatry Res 153:171-7. 2007
..The meaningful number of subjects meeting criteria for our algorithm of neurasthenia suggests that further study of this syndrome employing exact ICD-10 diagnostic criteria is warranted...
- Serum hormones in boys prenatally exposed to polychlorinated biphenyls and dibenzofurans
Ping-Chi Hsu
Department of Safety, Health and Environmental Engineering, National Kaohsiung First University of Science and Technology, Kaohsiung, Taiwan
J Toxicol Environ Health A 68:1447-56. 2005
..Further studies are needed to identify the congeners of PCBs/PCDFs responsible for disruption of the endocrine system, as well as the mechanisms of such disruption...
